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The map label for this gene is ribD [H]

Identifier: 182682363

GI number: 182682363

Start: 2049424

End: 2050518

Strand: Reverse

Name: ribD [H]

Synonym: XfasM23_1848

Alternate gene names: 182682363

Gene position: 2050518-2049424 (Counterclockwise)

Preceding gene: 182682364

Following gene: 182682362

Centisome position: 80.87

GC content: 59.0

Gene sequence:

>1095_bases
ATGAGCGCATTTTCCGCGGATGATCACCGTCACATGGAACGGGCCTTGTGTTTGGCTGAGCGTGGTGCTTACACGACGCG
TCCTAACCCAATGGTGGGTTGTGTGATTGTGCGTGATGGTGAAGTAGTGGGAGAGGGTTGGCACCAGCGTGCTGGCGATC
CGCATGCTGAGGTATTTGCATTGTGTGCGGCTGGAGACCGCGCACGAGGTGCAACGGCTTACGTCACGTTGGAGCCGTGT
GCGCACTCGGGGCGTACTCCGCCGTGTGCGATGGCGTTGATTGATGCCGGAGTGAGACGGGTGGTGGCGGCGATGGTCGA
TCCATTTCCGTTAGTCAATGGTGGGGGAGTCACTCTGTTACGTGCGGCTGGGGTGACGGTTGAGCATGGTTTGATGGAGG
CGCAGGCGCGCGCACTCAACCGTGGCTTTCTGTCGCGGGTGGAGCGTGGTCGGCCATGGGTGCGGATCAAGCTTGGTAGC
AGTTTGGATGGGCGTACCGCGTTGGCTAGTGGCGAATCCAAGTGGATTACCGGGGAGGCGGCACGTGCTGATGTGCAGCG
TTGGCGCGCGCGCGCTAGCGCGATTTTGACGGGGGCTGGGACGGTGCTTGCCGATGATCCGGCGTTAACGGTGCGCCTGG
GTGGGGAGGAGGGAGCGTTTTTGCCGCCGTTGCGGGTGGTGCTTGATTCTAGCTTGCGTTCACTTAGTTGCGTGAAGGTG
CGTGACGGTACTGCACCAACGTTGTATCTGCATGGTTTTGGGGTCACGTCCCCTGTGTTGCAACACGTCGATTTTTCCGA
GGTTCAGCAACGTGATGCTGGGCTTGATCTGGAGGCTGTGTTACGCCTGTTGGGTGAGCGTGGCATCAATGAGGTGCAGG
TTGAGGCTGGGGCGACGTTATGCGGGGCCTTGCTGCACGCTGGGTTGGTGGATGAGTTGCTGATTTATATTGCACCGTTG
TTGCTGGGTGATACGGCACGGCCATTACTGGCTGGATTGGATATCGGGCGCATGGATCAGTGCATTGGTTTGAAGGTGCT
GGAGGTCGCTCAGGTCGGCAATGATCTGCGATTGTTATTACGTCCGTGTGGTTGA

Upstream 100 bases:

>100_bases
AGTATGTCTTTTACTGTTGTTAGCTTGTCTTGTCCTTGATAAGGCTGCGGTTACCCTGTTTGTCGAGTATGGTGATTCCC
CTGGATAGGGAAGCTGAGCG

Downstream 100 bases:

>100_bases
ATGGCGGTAGAGGTGCCCATTGGCATTTCAGGTCTCCAGGGGGCATGTTGGCGCACGTTTTCCATCGTAGGAGTTGTGGT
GTTGCTGTGGTTGCATGGGG

Product: riboflavin biosynthesis protein RibD

Products: NA

Alternate protein names: Diaminohydroxyphosphoribosylaminopyrimidine deaminase; DRAP deaminase; Riboflavin-specific deaminase; 5-amino-6-(5-phosphoribosylamino)uracil reductase; HTP reductase [H]

Number of amino acids: Translated: 364; Mature: 363

Protein sequence:

>364_residues
MSAFSADDHRHMERALCLAERGAYTTRPNPMVGCVIVRDGEVVGEGWHQRAGDPHAEVFALCAAGDRARGATAYVTLEPC
AHSGRTPPCAMALIDAGVRRVVAAMVDPFPLVNGGGVTLLRAAGVTVEHGLMEAQARALNRGFLSRVERGRPWVRIKLGS
SLDGRTALASGESKWITGEAARADVQRWRARASAILTGAGTVLADDPALTVRLGGEEGAFLPPLRVVLDSSLRSLSCVKV
RDGTAPTLYLHGFGVTSPVLQHVDFSEVQQRDAGLDLEAVLRLLGERGINEVQVEAGATLCGALLHAGLVDELLIYIAPL
LLGDTARPLLAGLDIGRMDQCIGLKVLEVAQVGNDLRLLLRPCG

Sequences:

>Translated_364_residues
MSAFSADDHRHMERALCLAERGAYTTRPNPMVGCVIVRDGEVVGEGWHQRAGDPHAEVFALCAAGDRARGATAYVTLEPC
AHSGRTPPCAMALIDAGVRRVVAAMVDPFPLVNGGGVTLLRAAGVTVEHGLMEAQARALNRGFLSRVERGRPWVRIKLGS
SLDGRTALASGESKWITGEAARADVQRWRARASAILTGAGTVLADDPALTVRLGGEEGAFLPPLRVVLDSSLRSLSCVKV
RDGTAPTLYLHGFGVTSPVLQHVDFSEVQQRDAGLDLEAVLRLLGERGINEVQVEAGATLCGALLHAGLVDELLIYIAPL
LLGDTARPLLAGLDIGRMDQCIGLKVLEVAQVGNDLRLLLRPCG
>Mature_363_residues
SAFSADDHRHMERALCLAERGAYTTRPNPMVGCVIVRDGEVVGEGWHQRAGDPHAEVFALCAAGDRARGATAYVTLEPCA
HSGRTPPCAMALIDAGVRRVVAAMVDPFPLVNGGGVTLLRAAGVTVEHGLMEAQARALNRGFLSRVERGRPWVRIKLGSS
LDGRTALASGESKWITGEAARADVQRWRARASAILTGAGTVLADDPALTVRLGGEEGAFLPPLRVVLDSSLRSLSCVKVR
DGTAPTLYLHGFGVTSPVLQHVDFSEVQQRDAGLDLEAVLRLLGERGINEVQVEAGATLCGALLHAGLVDELLIYIAPLL
LGDTARPLLAGLDIGRMDQCIGLKVLEVAQVGNDLRLLLRPCG

Specific function: Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'-phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)- pyrimidinedione 5'-phosphate [H]

COG id: COG1985

COG function: function code H; Pyrimidine reductase, riboflavin biosynthesis

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the HTP reductase family [H]

Homologues:

Organism=Escherichia coli, GI1786616, Length=363, Percent_Identity=51.5151515151515, Blast_Score=338, Evalue=2e-94,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016192
- InterPro:   IPR002125
- InterPro:   IPR016193
- InterPro:   IPR004794
- InterPro:   IPR011549
- InterPro:   IPR002734 [H]

Pfam domain/function: PF00383 dCMP_cyt_deam_1; PF01872 RibD_C [H]

EC number: =3.5.4.26; =1.1.1.193 [H]

Molecular weight: Translated: 38575; Mature: 38444

Theoretical pI: Translated: 6.78; Mature: 6.78

Prosite motif: PS00903 CYT_DCMP_DEAMINASES

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.5 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.5 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAFSADDHRHMERALCLAERGAYTTRPNPMVGCVIVRDGEVVGEGWHQRAGDPHAEVFA
CCCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEECCCHHHCCCCCHHHHEE
LCAAGDRARGATAYVTLEPCAHSGRTPPCAMALIDAGVRRVVAAMVDPFPLVNGGGVTLL
EECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEE
RAAGVTVEHGLMEAQARALNRGFLSRVERGRPWVRIKLGSSLDGRTALASGESKWITGEA
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCEEECHH
ARADVQRWRARASAILTGAGTVLADDPALTVRLGGEEGAFLPPLRVVLDSSLRSLSCVKV
HHHHHHHHHHHHHHEEECCCEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEE
RDGTAPTLYLHGFGVTSPVLQHVDFSEVQQRDAGLDLEAVLRLLGERGINEVQVEAGATL
ECCCCCEEEEECCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCHHH
CGALLHAGLVDELLIYIAPLLLGDTARPLLAGLDIGRMDQCIGLKVLEVAQVGNDLRLLL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
RPCG
ECCC
>Mature Secondary Structure 
SAFSADDHRHMERALCLAERGAYTTRPNPMVGCVIVRDGEVVGEGWHQRAGDPHAEVFA
CCCCCCHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCEECCCHHHCCCCCHHHHEE
LCAAGDRARGATAYVTLEPCAHSGRTPPCAMALIDAGVRRVVAAMVDPFPLVNGGGVTLL
EECCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCEECCCCEEEE
RAAGVTVEHGLMEAQARALNRGFLSRVERGRPWVRIKLGSSLDGRTALASGESKWITGEA
EECCCCHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCEEECCCCCCEEECHH
ARADVQRWRARASAILTGAGTVLADDPALTVRLGGEEGAFLPPLRVVLDSSLRSLSCVKV
HHHHHHHHHHHHHHEEECCCEEEECCCEEEEEECCCCCCCCCHHHHHHHHHHCCEEEEEE
RDGTAPTLYLHGFGVTSPVLQHVDFSEVQQRDAGLDLEAVLRLLGERGINEVQVEAGATL
ECCCCCEEEEECCCCHHHHHHHCCHHHHHHHHCCCCHHHHHHHHHHCCCCEEEECCCHHH
CGALLHAGLVDELLIYIAPLLLGDTARPLLAGLDIGRMDQCIGLKVLEVAQVGNDLRLLL
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHCCCCCCHHHHHHHHHHHHHHCCCCEEEEE
RPCG
ECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1406588; 9278503; 9068650 [H]