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The map label for this gene is thiL [H]

Identifier: 182682358

GI number: 182682358

Start: 2045074

End: 2046048

Strand: Reverse

Name: thiL [H]

Synonym: XfasM23_1843

Alternate gene names: 182682358

Gene position: 2046048-2045074 (Counterclockwise)

Preceding gene: 182682359

Following gene: 182682357

Centisome position: 80.69

GC content: 55.59

Gene sequence:

>975_bases
ATGCTTGAGTTTGATTTGATTGACCGCTTGCGTGGTCGTATCCGTCCGCGCCAGGACGTGTTGTTAGGTGTGGGCGATGA
TGCTGCACTCTTGCAGCCACCACAGGGTGAACCATTGGTGGTCACCACCGATACGCTGAATGCCGGTGTGCATTTCCCAG
TTGAGACCCATCCTGAGGATCTTGGTTGGAAAACGCTTGCGGTCAGTGTCTCGGATTTGGCGGCGATGGGGGCAACGCCA
CGTTGGTGTACGTTGTCTTTGTCGTTGCTCCAGGTGGATATGGCATGGATTGATGCTTTTGCTGATGGATTTTTCGAGCT
GGCCGATCTACACGGTCTTGTTCTGGTCGGTGGTGACACGACATACGGCCCCTTGGCTACGTCGGTGACCGCGATTGGTT
GCGTGCCACCGGGTATGGCCTTGCGTCGTGATGGTGCTTGTATTGGCGATGATATTTGGGTGACTGGCCGTCCTGGCGAG
GCTGCTGCGGCATTGGCGATGTGGTGTGCTGGGATGCTTGACATTACCAAGTGTGCGCCTGATCCGCGCTGTGAGATATT
GCGCCAGAGGTTGTTACGTCCGACGCCTCGGGTGGAAGTAGGGCTCGCTTTGCGGGGATTGGTGCATGCTGCGGTGGATC
TTTCCGATGGCCTTCTCGCCGATTTGGGGCACATTTGTGCAAGCAGTGGGGTTGGAGCAGTGTTGGAATGTACGTCCTTA
CCGCGTGTTGCAGTGCATGGCGGATGGGATGAGGCGCAGGTTGCTTCTTGGCAATTGGCCGGTGGTGATGATTATGAGCT
TTGTTTTACAGCAGCACCGCAGTGTGGTGCCCCAATACAGGACGTGTGCGCCACTTTGGGTGTTGAGGTGACACGCATTG
GGCGCATTGTGGTTGGTGAGACAGTGCAGGTTCTCAATGCTGCGGGTGTGCCTTGGCAACTTTCGAGAAAAGGTTATCAG
CACTTCATTGATTAA

Upstream 100 bases:

>100_bases
GCTTGGATGAAGTTTGCCGTTCCTTAAGTCGTCGCGTAGCTAGCAGCTGCCAGCAGCGACGGATGTTCGATTTCTTCCGT
ACTGGTATCGCGTCAGGTCA

Downstream 100 bases:

>100_bases
ATGATGGATGTGTGATTGGTATTGGGCCTGTAGCGCTTTTCCCTCCGTTACTTGCAGGTGATGACTCATTTGGCGAAGGG
AGAACGCTATGTTTTTCATC

Product: thiamine monophosphate kinase

Products: NA

Alternate protein names: Thiamine-phosphate kinase [H]

Number of amino acids: Translated: 324; Mature: 324

Protein sequence:

>324_residues
MLEFDLIDRLRGRIRPRQDVLLGVGDDAALLQPPQGEPLVVTTDTLNAGVHFPVETHPEDLGWKTLAVSVSDLAAMGATP
RWCTLSLSLLQVDMAWIDAFADGFFELADLHGLVLVGGDTTYGPLATSVTAIGCVPPGMALRRDGACIGDDIWVTGRPGE
AAAALAMWCAGMLDITKCAPDPRCEILRQRLLRPTPRVEVGLALRGLVHAAVDLSDGLLADLGHICASSGVGAVLECTSL
PRVAVHGGWDEAQVASWQLAGGDDYELCFTAAPQCGAPIQDVCATLGVEVTRIGRIVVGETVQVLNAAGVPWQLSRKGYQ
HFID

Sequences:

>Translated_324_residues
MLEFDLIDRLRGRIRPRQDVLLGVGDDAALLQPPQGEPLVVTTDTLNAGVHFPVETHPEDLGWKTLAVSVSDLAAMGATP
RWCTLSLSLLQVDMAWIDAFADGFFELADLHGLVLVGGDTTYGPLATSVTAIGCVPPGMALRRDGACIGDDIWVTGRPGE
AAAALAMWCAGMLDITKCAPDPRCEILRQRLLRPTPRVEVGLALRGLVHAAVDLSDGLLADLGHICASSGVGAVLECTSL
PRVAVHGGWDEAQVASWQLAGGDDYELCFTAAPQCGAPIQDVCATLGVEVTRIGRIVVGETVQVLNAAGVPWQLSRKGYQ
HFID
>Mature_324_residues
MLEFDLIDRLRGRIRPRQDVLLGVGDDAALLQPPQGEPLVVTTDTLNAGVHFPVETHPEDLGWKTLAVSVSDLAAMGATP
RWCTLSLSLLQVDMAWIDAFADGFFELADLHGLVLVGGDTTYGPLATSVTAIGCVPPGMALRRDGACIGDDIWVTGRPGE
AAAALAMWCAGMLDITKCAPDPRCEILRQRLLRPTPRVEVGLALRGLVHAAVDLSDGLLADLGHICASSGVGAVLECTSL
PRVAVHGGWDEAQVASWQLAGGDDYELCFTAAPQCGAPIQDVCATLGVEVTRIGRIVVGETVQVLNAAGVPWQLSRKGYQ
HFID

Specific function: Thiamine biosynthesis. [C]

COG id: COG0611

COG function: function code H; Thiamine monophosphate kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the thiamine-monophosphate kinase family [H]

Homologues:

Organism=Escherichia coli, GI1786619, Length=322, Percent_Identity=44.7204968944099, Blast_Score=241, Evalue=3e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000728
- InterPro:   IPR010918
- InterPro:   IPR016188
- InterPro:   IPR006283 [H]

Pfam domain/function: PF00586 AIRS; PF02769 AIRS_C [H]

EC number: =2.7.4.16 [H]

Molecular weight: Translated: 34304; Mature: 34304

Theoretical pI: Translated: 4.44; Mature: 4.44

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.4 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
5.2 %Cys+Met (Translated Protein)
3.4 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
5.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLEFDLIDRLRGRIRPRQDVLLGVGDDAALLQPPQGEPLVVTTDTLNAGVHFPVETHPED
CCCHHHHHHHHHCCCCCHHEEEECCCCHHEECCCCCCEEEEEECCCCCCEECCCCCCCCC
LGWKTLAVSVSDLAAMGATPRWCTLSLSLLQVDMAWIDAFADGFFELADLHGLVLVGGDT
CCCEEEEEEHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
TYGPLATSVTAIGCVPPGMALRRDGACIGDDIWVTGRPGEAAAALAMWCAGMLDITKCAP
CCCCHHHHHEEEECCCCCCCEECCCCEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCC
DPRCEILRQRLLRPTPRVEVGLALRGLVHAAVDLSDGLLADLGHICASSGVGAVLECTSL
CHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCC
PRVAVHGGWDEAQVASWQLAGGDDYELCFTAAPQCGAPIQDVCATLGVEVTRIGRIVVGE
CEEEEECCCCCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHCEEEECC
TVQVLNAAGVPWQLSRKGYQHFID
HHHHHHCCCCCEEHHHHHHHHHCC
>Mature Secondary Structure
MLEFDLIDRLRGRIRPRQDVLLGVGDDAALLQPPQGEPLVVTTDTLNAGVHFPVETHPED
CCCHHHHHHHHHCCCCCHHEEEECCCCHHEECCCCCCEEEEEECCCCCCEECCCCCCCCC
LGWKTLAVSVSDLAAMGATPRWCTLSLSLLQVDMAWIDAFADGFFELADLHGLVLVGGDT
CCCEEEEEEHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHCCCEEEEECCCC
TYGPLATSVTAIGCVPPGMALRRDGACIGDDIWVTGRPGEAAAALAMWCAGMLDITKCAP
CCCCHHHHHEEEECCCCCCCEECCCCEECCCEEEECCCCHHHHHHHHHHHHHHHHHHCCC
DPRCEILRQRLLRPTPRVEVGLALRGLVHAAVDLSDGLLADLGHICASSGVGAVLECTSL
CHHHHHHHHHHCCCCCCEEHHHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCC
PRVAVHGGWDEAQVASWQLAGGDDYELCFTAAPQCGAPIQDVCATLGVEVTRIGRIVVGE
CEEEEECCCCCCCEEEEEECCCCCCEEEEECCCCCCCCHHHHHHHHCCCHHHHCEEEECC
TVQVLNAAGVPWQLSRKGYQHFID
HHHHHHCCCCCEEHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11677609 [H]