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The map label for this gene is rppH

Identifier: 182682287

GI number: 182682287

Start: 1959581

End: 1960153

Strand: Reverse

Name: rppH

Synonym: XfasM23_1770

Alternate gene names: 182682287

Gene position: 1960153-1959581 (Counterclockwise)

Preceding gene: 182682288

Following gene: 182682286

Centisome position: 77.3

GC content: 51.31

Gene sequence:

>573_bases
GTGATCGATCCGGACGGTTACCGACCTAACGTTGGTATTGTGTTGATCCGTAGGGATGGGCAGGTGTTCTGGGGACGTCG
CGTCCGCCGTGATGGTTGGCAGTTCCCACAAGGCGGCATGCATTCTGACGAAACTCCAGTTGAAGCTATGTACCGTGAGT
TGAATGAAGAGACTGGATTGTTGCCAGAGCACGTGCAATTAGTTGGTGCTACGCCAGGCTGGCTGCGTTATCGATTGCCG
AGTCAAGCCGTACGCTGCAATCGATCCCAGATGTGTATCGGCCAAAAGCAGGTCTGGTTCCTGCTGCAACTGATAGGTGA
TGAATCGCATGTACAACTCGACCAGAGTGAGAATCCCGAGTTTGATCATTGGCGTTGGGTGAGTTTTTGGTACCCAATTG
AGCATGTCGTCATGTTTAAGCGCAGTGTTTATGCGCGTGCGTTGTGCCAGTTAGCATCACTGGCGCAGCAGGTGGTCGGT
CTTGAGGTAGGGACGATGCCGCAGTACGTACAGGATATTTGTTTGCTTAATGTTGGATACAAGCATTTACCTAATTGGGT
GAGTCGGTATTGA

Upstream 100 bases:

>100_bases
TTTTTGATTCTAGTTCGTCAAGCTGCGTGTGCCGCTACTTGGCAGAACCCTAGAGTCATGGCAGAGTCGACCACAGTAAA
TTTTTTCAGGAGTCCGCATC

Downstream 100 bases:

>100_bases
TGTAAGCGGATAGGATATTAGTAACGATTAATTTTTGTAATTGACATTCATTCTCATCTTGTGGTTGAATGGTTATGTCC
CACTTAGGGATGCCACTACC

Product: dinucleoside polyphosphate hydrolase

Products: NA

Alternate protein names: (Di)nucleoside polyphosphate hydrolase

Number of amino acids: Translated: 190; Mature: 190

Protein sequence:

>190_residues
MIDPDGYRPNVGIVLIRRDGQVFWGRRVRRDGWQFPQGGMHSDETPVEAMYRELNEETGLLPEHVQLVGATPGWLRYRLP
SQAVRCNRSQMCIGQKQVWFLLQLIGDESHVQLDQSENPEFDHWRWVSFWYPIEHVVMFKRSVYARALCQLASLAQQVVG
LEVGTMPQYVQDICLLNVGYKHLPNWVSRY

Sequences:

>Translated_190_residues
MIDPDGYRPNVGIVLIRRDGQVFWGRRVRRDGWQFPQGGMHSDETPVEAMYRELNEETGLLPEHVQLVGATPGWLRYRLP
SQAVRCNRSQMCIGQKQVWFLLQLIGDESHVQLDQSENPEFDHWRWVSFWYPIEHVVMFKRSVYARALCQLASLAQQVVG
LEVGTMPQYVQDICLLNVGYKHLPNWVSRY
>Mature_190_residues
MIDPDGYRPNVGIVLIRRDGQVFWGRRVRRDGWQFPQGGMHSDETPVEAMYRELNEETGLLPEHVQLVGATPGWLRYRLP
SQAVRCNRSQMCIGQKQVWFLLQLIGDESHVQLDQSENPEFDHWRWVSFWYPIEHVVMFKRSVYARALCQLASLAQQVVG
LEVGTMPQYVQDICLLNVGYKHLPNWVSRY

Specific function: Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage

COG id: COG0494

COG function: function code LR; NTP pyrophosphohydrolases including oxidative damage repair enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 nudix hydrolase domain

Homologues:

Organism=Escherichia coli, GI1789194, Length=154, Percent_Identity=53.8961038961039, Blast_Score=182, Evalue=1e-47,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPPH_XYLF2 (B2I897)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830447.1
- ProteinModelPortal:   B2I897
- SMR:   B2I897
- GeneID:   6203024
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1770
- HOGENOM:   HBG302451
- OMA:   GQKQIWY
- ProtClustDB:   PRK00714
- HAMAP:   MF_00298
- InterPro:   IPR020084
- InterPro:   IPR000086
- InterPro:   IPR015797
- InterPro:   IPR022927
- Gene3D:   G3DSA:3.90.79.10

Pfam domain/function: PF00293 NUDIX; SSF55811 NUDIX_hydrolase

EC number: 3.6.1.- [C]

Molecular weight: Translated: 22215; Mature: 22215

Theoretical pI: Translated: 7.11; Mature: 7.11

Prosite motif: PS51462 NUDIX; PS00893 NUDIX_BOX

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIDPDGYRPNVGIVLIRRDGQVFWGRRVRRDGWQFPQGGMHSDETPVEAMYRELNEETGL
CCCCCCCCCCCEEEEEEECCCEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
LPEHVQLVGATPGWLRYRLPSQAVRCNRSQMCIGQKQVWFLLQLIGDESHVQLDQSENPE
CHHHHEEEECCCCCEEECCCHHHHHCCCHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCC
FDHWRWVSFWYPIEHVVMFKRSVYARALCQLASLAQQVVGLEVGTMPQYVQDICLLNVGY
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCH
KHLPNWVSRY
HHCCHHHHCC
>Mature Secondary Structure
MIDPDGYRPNVGIVLIRRDGQVFWGRRVRRDGWQFPQGGMHSDETPVEAMYRELNEETGL
CCCCCCCCCCCEEEEEEECCCEEHHHHHHCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
LPEHVQLVGATPGWLRYRLPSQAVRCNRSQMCIGQKQVWFLLQLIGDESHVQLDQSENPE
CHHHHEEEECCCCCEEECCCHHHHHCCCHHHHCCHHHHHHHHHHHCCCCEEEECCCCCCC
FDHWRWVSFWYPIEHVVMFKRSVYARALCQLASLAQQVVGLEVGTMPQYVQDICLLNVGY
CCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHCCH
KHLPNWVSRY
HHCCHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA