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The map label for this gene is mlaC [H]

Identifier: 182682269

GI number: 182682269

Start: 1939642

End: 1940298

Strand: Direct

Name: mlaC [H]

Synonym: XfasM23_1751

Alternate gene names: 182682269

Gene position: 1939642-1940298 (Clockwise)

Preceding gene: 182682268

Following gene: 182682270

Centisome position: 76.49

GC content: 50.99

Gene sequence:

>657_bases
ATGAAGACCACACTGTTCTACATCATGTTCGCTTACGCTCTGTCAACCGCATTTCCATCCATGATGCTGGCTCAGGCATC
ATCAATCGCCGAGGTCAACCAAGGCCAAGCCTCTAAGATGGTGATTGACTCGAGTGCGCGCGTCCTATCCACGCTAGAAC
AGCAGCGTGCCCAATTTCGCCAGGACCCCAAAGCGCTGCGTCAGTTCATGGAGACTGAATTCACTACTATTTTTGATCGT
GATTACGCTGCACGTTTGGTACTAGGGAAATACGCTCGTAACGCATCAGACACCGATGTAAAGCTGTTCGCCGACGCAAT
CGGCGAAAATCTCATGCAACGTTACGGCAATGCGCTGCTGACCTTTGAGGGTAAACCCAGTTTCCGCGCCAAGTCCGAGA
GCCGCCTACCAGGCAATCGTAATGTCAGAGTTTCGACAGAATTGATCCGTTCTGGAGCTGACCCTATTGCAGTTGACTAC
CTGCTACGTAATGTTAACGGCCAATGGAAAATCTTCGATGTCATGATCGAAGGCATTTCTTACGTACAAACTTTCAGAAA
TCAGTTCGACGCACCGCTGCGCCAAAAGGGGATCGCTCAGGTTGCCGCAGAGCTGCGCAGTGATAACCTGCAAGTCGGGA
AGAGCAATGGGAAGTGA

Upstream 100 bases:

>100_bases
ACATGTTCAGTGGCGGCAGCGATAAATCCACATCCAGCAACACCACCAGCACAACCGATCACGCTGCCTCCTCTCACACA
GACACTCAAGAAACTCACCA

Downstream 100 bases:

>100_bases
GACTAAGCTACATCGCGACGGTAACTCACTGGTGTTAAGCGGCCCTCTTAATCGCGATGCAGCCATCGGATTATGGTCTG
AAATCCAAGCGCAAAGTAAA

Product: toluene tolerance family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 218; Mature: 218

Protein sequence:

>218_residues
MKTTLFYIMFAYALSTAFPSMMLAQASSIAEVNQGQASKMVIDSSARVLSTLEQQRAQFRQDPKALRQFMETEFTTIFDR
DYAARLVLGKYARNASDTDVKLFADAIGENLMQRYGNALLTFEGKPSFRAKSESRLPGNRNVRVSTELIRSGADPIAVDY
LLRNVNGQWKIFDVMIEGISYVQTFRNQFDAPLRQKGIAQVAAELRSDNLQVGKSNGK

Sequences:

>Translated_218_residues
MKTTLFYIMFAYALSTAFPSMMLAQASSIAEVNQGQASKMVIDSSARVLSTLEQQRAQFRQDPKALRQFMETEFTTIFDR
DYAARLVLGKYARNASDTDVKLFADAIGENLMQRYGNALLTFEGKPSFRAKSESRLPGNRNVRVSTELIRSGADPIAVDY
LLRNVNGQWKIFDVMIEGISYVQTFRNQFDAPLRQKGIAQVAAELRSDNLQVGKSNGK
>Mature_218_residues
MKTTLFYIMFAYALSTAFPSMMLAQASSIAEVNQGQASKMVIDSSARVLSTLEQQRAQFRQDPKALRQFMETEFTTIFDR
DYAARLVLGKYARNASDTDVKLFADAIGENLMQRYGNALLTFEGKPSFRAKSESRLPGNRNVRVSTELIRSGADPIAVDY
LLRNVNGQWKIFDVMIEGISYVQTFRNQFDAPLRQKGIAQVAAELRSDNLQVGKSNGK

Specific function: Actively prevents phospholipid accumulation at the cell surface. Probably maintains lipid asymmetry in the outer membrane by retrograde trafficking of phospholipids from the outer membrane to the inner membrane. May transfer phospholipid across the peripl

COG id: COG2854

COG function: function code Q; ABC-type transport system involved in resistance to organic solvents, auxiliary component

Gene ontology:

Cell location: Periplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the mlaC/ttg2D family [H]

Homologues:

Organism=Escherichia coli, GI1789583, Length=190, Percent_Identity=27.3684210526316, Blast_Score=85, Evalue=3e-18,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023094
- InterPro:   IPR008869 [H]

Pfam domain/function: PF05494 Tol_Tol_Ttg2 [H]

EC number: NA

Molecular weight: Translated: 24473; Mature: 24473

Theoretical pI: Translated: 10.05; Mature: 10.05

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKTTLFYIMFAYALSTAFPSMMLAQASSIAEVNQGQASKMVIDSSARVLSTLEQQRAQFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCHHHHHHHHHHHHHHHH
QDPKALRQFMETEFTTIFDRDYAARLVLGKYARNASDTDVKLFADAIGENLMQRYGNALL
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEE
TFEGKPSFRAKSESRLPGNRNVRVSTELIRSGADPIAVDYLLRNVNGQWKIFDVMIEGIS
EECCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCHHHHHHHHHCCCCCEEHHHHHHHHHH
YVQTFRNQFDAPLRQKGIAQVAAELRSDNLQVGKSNGK
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCEECCCCCCC
>Mature Secondary Structure
MKTTLFYIMFAYALSTAFPSMMLAQASSIAEVNQGQASKMVIDSSARVLSTLEQQRAQFR
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHEEECCHHHHHHHHHHHHHHHH
QDPKALRQFMETEFTTIFDRDYAARLVLGKYARNASDTDVKLFADAIGENLMQRYGNALL
CCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHCCEEE
TFEGKPSFRAKSESRLPGNRNVRVSTELIRSGADPIAVDYLLRNVNGQWKIFDVMIEGIS
EECCCCCCCCCCCCCCCCCCCEEEHHHHHHCCCCHHHHHHHHHCCCCCEEHHHHHHHHHH
YVQTFRNQFDAPLRQKGIAQVAAELRSDNLQVGKSNGK
HHHHHHHHHCCCHHHHHHHHHHHHHHCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]