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The map label for this gene is hflC [H]

Identifier: 182682239

GI number: 182682239

Start: 1902316

End: 1903179

Strand: Reverse

Name: hflC [H]

Synonym: XfasM23_1721

Alternate gene names: 182682239

Gene position: 1903179-1902316 (Counterclockwise)

Preceding gene: 182682240

Following gene: 182682238

Centisome position: 75.06

GC content: 49.77

Gene sequence:

>864_bases
ATGAAAAATTATTTGTGGATTGTTGTTACGGCTGTGCTTTTTCTTAGTTTGTTCAGCTCGATCTTTGTAGTGCGCGAGGA
TCAGACTGCGATGGTCATCAATCTTGGTCGTGTGGTGCGTTACGACCTAAAGCCAGGTTTACATTTCAAGATCCCGTTGG
TTGAGTCGGTGCGTCTATTTGATCGTCGTTTCAAGGTGATGGCTACGGAGCCAGCGCGCTACTTTACTGCTGAACAGAAG
GATGTCAGTGTCGATTTTTTTGCAATTGGCTACATTGAAGACGTGCGTTCCTTTTACCGTGCTACCGGTGGCGATGAGTC
TCAAGCTGCCGCCCGTTTGGCGCCTATCATCACTGATTCGCTGCGTAACCAGATTAACTCGCGCACCTTGCAGGAGTTGG
TGTCTGGAGATCGTAGTGAGTTGATTGCTGGTCAATTGAAAAGTATCAATGCTGCGACTAAAGGGTTAGGTGTGCATATT
GTTGATCTTCGAATCAAGCAGATTGAGCTGCCAGTAGACAGCCAGGTGATCAGTGATGTTTACGAACGCATGCGTGCCCA
GCGTAAGCAAGAGGCTGCCAAGTTGCGTGCTGAGGGTGAGGAGCGGTCGTTGAGCATTCGTGCCCAGGCCGATCGCGAGT
CCACTGTGTTAATTGCTGATGCTGAGCGTGATGCCCAGAAATTGCGTGGTGAGGGTGATGCTGAAGCTGCGCGTGTCTAC
GGCAAAGCTGGTGCTAATGACCCCGCGTTCTACGCTTTTTACCGTAGTCTGGAGGCTTACCGAAACGGTATGGCTGATGG
CAATGGTGTCATTGTGCTCGACAAGAACGATCCGTTCTTGAAGTACTTTAAGAGCGATCATTGA

Upstream 100 bases:

>100_bases
AGGATCTATTGATCCCCGAATCGCTTAGCAAGCCATCTAATGAGAATATCCGTAATCCGCAGCGCGTTGTCCGTCCTGCA
GGCCGTGAAGGAGCTCCTCT

Downstream 100 bases:

>100_bases
GCGGTGCTTGTTCTGGTGTTGCAGCGATGCCTTCGCGTATCTGAAAGACAGACTGTCAAGCGATGATAGGTGGTGGTTTC
CTGTCATTTCTGTTTTGTGC

Product: HflC protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 287; Mature: 287

Protein sequence:

>287_residues
MKNYLWIVVTAVLFLSLFSSIFVVREDQTAMVINLGRVVRYDLKPGLHFKIPLVESVRLFDRRFKVMATEPARYFTAEQK
DVSVDFFAIGYIEDVRSFYRATGGDESQAAARLAPIITDSLRNQINSRTLQELVSGDRSELIAGQLKSINAATKGLGVHI
VDLRIKQIELPVDSQVISDVYERMRAQRKQEAAKLRAEGEERSLSIRAQADRESTVLIADAERDAQKLRGEGDAEAARVY
GKAGANDPAFYAFYRSLEAYRNGMADGNGVIVLDKNDPFLKYFKSDH

Sequences:

>Translated_287_residues
MKNYLWIVVTAVLFLSLFSSIFVVREDQTAMVINLGRVVRYDLKPGLHFKIPLVESVRLFDRRFKVMATEPARYFTAEQK
DVSVDFFAIGYIEDVRSFYRATGGDESQAAARLAPIITDSLRNQINSRTLQELVSGDRSELIAGQLKSINAATKGLGVHI
VDLRIKQIELPVDSQVISDVYERMRAQRKQEAAKLRAEGEERSLSIRAQADRESTVLIADAERDAQKLRGEGDAEAARVY
GKAGANDPAFYAFYRSLEAYRNGMADGNGVIVLDKNDPFLKYFKSDH
>Mature_287_residues
MKNYLWIVVTAVLFLSLFSSIFVVREDQTAMVINLGRVVRYDLKPGLHFKIPLVESVRLFDRRFKVMATEPARYFTAEQK
DVSVDFFAIGYIEDVRSFYRATGGDESQAAARLAPIITDSLRNQINSRTLQELVSGDRSELIAGQLKSINAATKGLGVHI
VDLRIKQIELPVDSQVISDVYERMRAQRKQEAAKLRAEGEERSLSIRAQADRESTVLIADAERDAQKLRGEGDAEAARVY
GKAGANDPAFYAFYRSLEAYRNGMADGNGVIVLDKNDPFLKYFKSDH

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=314, Percent_Identity=35.9872611464968, Blast_Score=185, Evalue=4e-48,
Organism=Caenorhabditis elegans, GI32566490, Length=171, Percent_Identity=28.0701754385965, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 32279; Mature: 32279

Theoretical pI: Translated: 8.65; Mature: 8.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNYLWIVVTAVLFLSLFSSIFVVREDQTAMVINLGRVVRYDLKPGLHFKIPLVESVRLF
CCCCHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCEEEEECCCCCEEECCHHHHHHHH
DRRFKVMATEPARYFTAEQKDVSVDFFAIGYIEDVRSFYRATGGDESQAAARLAPIITDS
HHHHHEEEECCHHHEECCCCCCEEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LRNQINSRTLQELVSGDRSELIAGQLKSINAATKGLGVHIVDLRIKQIELPVDSQVISDV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHHHH
YERMRAQRKQEAAKLRAEGEERSLSIRAQADRESTVLIADAERDAQKLRGEGDAEAARVY
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECHHHHHHHCCCCCHHHHHHH
GKAGANDPAFYAFYRSLEAYRNGMADGNGVIVLDKNDPFLKYFKSDH
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHCCCC
>Mature Secondary Structure
MKNYLWIVVTAVLFLSLFSSIFVVREDQTAMVINLGRVVRYDLKPGLHFKIPLVESVRLF
CCCCHHHHHHHHHHHHHHHHHEEEECCCEEEEEECCCEEEEECCCCCEEECCHHHHHHHH
DRRFKVMATEPARYFTAEQKDVSVDFFAIGYIEDVRSFYRATGGDESQAAARLAPIITDS
HHHHHEEEECCHHHEECCCCCCEEEEEEEHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHH
LRNQINSRTLQELVSGDRSELIAGQLKSINAATKGLGVHIVDLRIKQIELPVDSQVISDV
HHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEEEEEECCCCHHHHHHH
YERMRAQRKQEAAKLRAEGEERSLSIRAQADRESTVLIADAERDAQKLRGEGDAEAARVY
HHHHHHHHHHHHHHHHCCCCCCEEEEEEECCCCCEEEEEECHHHHHHHCCCCCHHHHHHH
GKAGANDPAFYAFYRSLEAYRNGMADGNGVIVLDKNDPFLKYFKSDH
CCCCCCCHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 7542800 [H]