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The map label for this gene is yjcC [H]

Identifier: 182682227

GI number: 182682227

Start: 1886719

End: 1888311

Strand: Reverse

Name: yjcC [H]

Synonym: XfasM23_1709

Alternate gene names: 182682227

Gene position: 1888311-1886719 (Counterclockwise)

Preceding gene: 182682229

Following gene: 182682226

Centisome position: 74.47

GC content: 51.6

Gene sequence:

>1593_bases
TTGTTCTCATTTCGTGACTCCCGCTTGAAACGTTGTTGGACTCTTATCGTCGGTGCCACGCTTTGCATAGCGTGTCTTTC
TGTTTCAATTGCATTGACTGATGGCTACGTTTGGGTGACGACGCAGCGTCACGAACAACAGCGCCTGCGCGACTTGGCGC
AGCAAATGGGTCAACGGGTGGATCGCGCCGTTTCCGAATCATTGCTGCTCCTGTCAGACATGGATCATGCGCACTTGGCC
CCGTGTTCTCCAGAACACATCGCACGGATGCGTGCATTGGTGCTGGCTACCCGCTACATCACAGAACTTGACTATGCCCC
GACTCAGAAACTGAGCTGTACATCGTGGGGGCCGTTTGATGGTGCATTCAAGCAGACGTTGACCAGCGATACCAGAAACG
ATGGCCTTGAATTGGTGAAGCGGGTGTCTTTACCGCTGAACCCTGAGCAGCGCCTGCTGGGCTTGCATCATGGTGACTAC
CATGCACTGATGAAGCTCAGCACCTTTATGGATTTTCCAATTCCACCCGGTGTGGAATTGGCACTGGCCACTATGGATGG
GGTACTGTTGCTGAGCACTGGTTCTCATGTGAAAGAACTGTTTAGTAACCCTGTGAATCAATCAGCGAGTGATCCTTCGC
ATGATGTGGTCGCAGCCCGCATTCAAAACCCTCATCATGATTGGCAGATCGCTGTCATTGAACCAATCCAACAGCTTGTG
GGTGCGGTACATCGCAAAGAGTGGCTGGCCATCCCGGTTGCCTTATTGGTTTCATTGAGTGTCAGCGGCTTAGCCATCCT
GTATTTGCGCCGGCGGCGCGCTCCGTTGGCCCGGTTGCGTCAGGCCATCCAGCGATGTGAATTCTTTGTCTGCTATCAGC
CGATTGTTTCACTGAGTGATGGGCGTTGCGTCGGTGCAGAAGCATTGGTGCGTTGGCGCCAGCAAGACGGCACATTGATC
TTGCCGGACCAATTCATTCCACTGGCCGAGCGGAGTGGTTTAATTCTTCCCATTACCGATCAAGTCATCGCAGCGTCCAT
GCGTGAATTAGGACCATTACTGGTGGCTGATCGTTCGTTGCACATTGCGATTAATGTTTCAGTGAAGGACATTGAATCAG
GACGCTTACTGGATGTATTGGCGCTTGCTTTACAAGACACTGGCCTATACAGAAAACAACTGTGGATCGAGGCGACTGAG
CGCAGTTTCATGGATGCACGTGCCGCACGCGAGCATATCGTGCGGCTACGAGAGGCTGGATATGCTGTAGTGATTGATGA
TTTTGGGACTGGTTATTCAAATTTGCAGTATTTGCAGCAACTGCCATTAGACGCTTTGAAGATTGATAAATCCTTCATTG
ATACGGTTGGTCGCGATGTCACTAACACAGCGGTTGCTTCGCACATCATCGACATTGCTAAGGAATTGGGCATGCGTACC
ATTGCTGAAGGTGTGGAGCGTGAGGAACAACTCGTCTATCTACGTGCCCGTGGTGTGGATATGGCTCAAGGCTGGTTGTT
CTCATCTCCGTTAAGCGTCGCTGAGTTCGTTGACTATCTTTCCCACAATCGCAGTATGCATCCCGATGACTGA

Upstream 100 bases:

>100_bases
GGGCCTCGGCAATCAGCCCAGGTGATTCCGTTGTTGTGATGCCAAGTAGAAAGAACATGGAAAATAGTGTTGATCAATAT
TTCGAGTCTTTGGACTCCCA

Downstream 100 bases:

>100_bases
GGTATTTTGTGCTTGTGGCATGGCTCCTTGGACGAGGTGTGCGACTTTTTGAAGTTGCTGTATGGATGGTACGGAGCAGC
GTTGGTGTGGTGGCGATAGC

Product: EAL domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 530; Mature: 530

Protein sequence:

>530_residues
MFSFRDSRLKRCWTLIVGATLCIACLSVSIALTDGYVWVTTQRHEQQRLRDLAQQMGQRVDRAVSESLLLLSDMDHAHLA
PCSPEHIARMRALVLATRYITELDYAPTQKLSCTSWGPFDGAFKQTLTSDTRNDGLELVKRVSLPLNPEQRLLGLHHGDY
HALMKLSTFMDFPIPPGVELALATMDGVLLLSTGSHVKELFSNPVNQSASDPSHDVVAARIQNPHHDWQIAVIEPIQQLV
GAVHRKEWLAIPVALLVSLSVSGLAILYLRRRRAPLARLRQAIQRCEFFVCYQPIVSLSDGRCVGAEALVRWRQQDGTLI
LPDQFIPLAERSGLILPITDQVIAASMRELGPLLVADRSLHIAINVSVKDIESGRLLDVLALALQDTGLYRKQLWIEATE
RSFMDARAAREHIVRLREAGYAVVIDDFGTGYSNLQYLQQLPLDALKIDKSFIDTVGRDVTNTAVASHIIDIAKELGMRT
IAEGVEREEQLVYLRARGVDMAQGWLFSSPLSVAEFVDYLSHNRSMHPDD

Sequences:

>Translated_530_residues
MFSFRDSRLKRCWTLIVGATLCIACLSVSIALTDGYVWVTTQRHEQQRLRDLAQQMGQRVDRAVSESLLLLSDMDHAHLA
PCSPEHIARMRALVLATRYITELDYAPTQKLSCTSWGPFDGAFKQTLTSDTRNDGLELVKRVSLPLNPEQRLLGLHHGDY
HALMKLSTFMDFPIPPGVELALATMDGVLLLSTGSHVKELFSNPVNQSASDPSHDVVAARIQNPHHDWQIAVIEPIQQLV
GAVHRKEWLAIPVALLVSLSVSGLAILYLRRRRAPLARLRQAIQRCEFFVCYQPIVSLSDGRCVGAEALVRWRQQDGTLI
LPDQFIPLAERSGLILPITDQVIAASMRELGPLLVADRSLHIAINVSVKDIESGRLLDVLALALQDTGLYRKQLWIEATE
RSFMDARAAREHIVRLREAGYAVVIDDFGTGYSNLQYLQQLPLDALKIDKSFIDTVGRDVTNTAVASHIIDIAKELGMRT
IAEGVEREEQLVYLRARGVDMAQGWLFSSPLSVAEFVDYLSHNRSMHPDD
>Mature_530_residues
MFSFRDSRLKRCWTLIVGATLCIACLSVSIALTDGYVWVTTQRHEQQRLRDLAQQMGQRVDRAVSESLLLLSDMDHAHLA
PCSPEHIARMRALVLATRYITELDYAPTQKLSCTSWGPFDGAFKQTLTSDTRNDGLELVKRVSLPLNPEQRLLGLHHGDY
HALMKLSTFMDFPIPPGVELALATMDGVLLLSTGSHVKELFSNPVNQSASDPSHDVVAARIQNPHHDWQIAVIEPIQQLV
GAVHRKEWLAIPVALLVSLSVSGLAILYLRRRRAPLARLRQAIQRCEFFVCYQPIVSLSDGRCVGAEALVRWRQQDGTLI
LPDQFIPLAERSGLILPITDQVIAASMRELGPLLVADRSLHIAINVSVKDIESGRLLDVLALALQDTGLYRKQLWIEATE
RSFMDARAAREHIVRLREAGYAVVIDDFGTGYSNLQYLQQLPLDALKIDKSFIDTVGRDVTNTAVASHIIDIAKELGMRT
IAEGVEREEQLVYLRARGVDMAQGWLFSSPLSVAEFVDYLSHNRSMHPDD

Specific function: Overexpression reduces biofilm formation [H]

COG id: COG4943

COG function: function code T; Predicted signal transduction protein containing sensor and EAL domains

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 EAL domain [H]

Homologues:

Organism=Escherichia coli, GI1790496, Length=519, Percent_Identity=28.9017341040462, Blast_Score=223, Evalue=2e-59,
Organism=Escherichia coli, GI87081743, Length=523, Percent_Identity=28.8718929254302, Blast_Score=223, Evalue=3e-59,
Organism=Escherichia coli, GI87081845, Length=266, Percent_Identity=35.7142857142857, Blast_Score=163, Evalue=3e-41,
Organism=Escherichia coli, GI1788502, Length=267, Percent_Identity=35.2059925093633, Blast_Score=156, Evalue=4e-39,
Organism=Escherichia coli, GI87081980, Length=244, Percent_Identity=36.0655737704918, Blast_Score=145, Evalue=4e-36,
Organism=Escherichia coli, GI1786507, Length=240, Percent_Identity=36.25, Blast_Score=141, Evalue=1e-34,
Organism=Escherichia coli, GI87081921, Length=249, Percent_Identity=34.5381526104418, Blast_Score=129, Evalue=6e-31,
Organism=Escherichia coli, GI1787541, Length=239, Percent_Identity=31.3807531380753, Blast_Score=129, Evalue=7e-31,
Organism=Escherichia coli, GI226510982, Length=243, Percent_Identity=36.2139917695473, Blast_Score=122, Evalue=4e-29,
Organism=Escherichia coli, GI1787055, Length=244, Percent_Identity=33.6065573770492, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1788849, Length=243, Percent_Identity=30.4526748971193, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI87082096, Length=241, Percent_Identity=25.3112033195021, Blast_Score=91, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001633 [H]

Pfam domain/function: PF00563 EAL [H]

EC number: NA

Molecular weight: Translated: 59258; Mature: 59258

Theoretical pI: Translated: 6.66; Mature: 6.66

Prosite motif: PS50883 EAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFSFRDSRLKRCWTLIVGATLCIACLSVSIALTDGYVWVTTQRHEQQRLRDLAQQMGQRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEECCHHHHHHHHHHHHHHHHHH
DRAVSESLLLLSDMDHAHLAPCSPEHIARMRALVLATRYITELDYAPTQKLSCTSWGPFD
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GAFKQTLTSDTRNDGLELVKRVSLPLNPEQRLLGLHHGDYHALMKLSTFMDFPIPPGVEL
HHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEE
ALATMDGVLLLSTGSHVKELFSNPVNQSASDPSHDVVAARIQNPHHDWQIAVIEPIQQLV
EEEECCCEEEEECCHHHHHHHCCCCCCCCCCCCHHHEEEEECCCCCCEEEHHHHHHHHHH
GAVHRKEWLAIPVALLVSLSVSGLAILYLRRRRAPLARLRQAIQRCEFFVCYQPIVSLSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEHHHHCCCC
GRCVGAEALVRWRQQDGTLILPDQFIPLAERSGLILPITDQVIAASMRELGPLLVADRSL
CCEECHHHHHHHHHCCCCEECCCCCCCHHCCCCEEEEEHHHHHHHHHHHCCCEEEECCEE
HIAINVSVKDIESGRLLDVLALALQDTGLYRKQLWIEATERSFMDARAAREHIVRLREAG
EEEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YAVVIDDFGTGYSNLQYLQQLPLDALKIDKSFIDTVGRDVTNTAVASHIIDIAKELGMRT
CEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHH
IAEGVEREEQLVYLRARGVDMAQGWLFSSPLSVAEFVDYLSHNRSMHPDD
HHHHHCHHHHEEEEEECCCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCCC
>Mature Secondary Structure
MFSFRDSRLKRCWTLIVGATLCIACLSVSIALTDGYVWVTTQRHEQQRLRDLAQQMGQRV
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEEECCEEEEECCHHHHHHHHHHHHHHHHHH
DRAVSESLLLLSDMDHAHLAPCSPEHIARMRALVLATRYITELDYAPTQKLSCTSWGPFD
HHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCC
GAFKQTLTSDTRNDGLELVKRVSLPLNPEQRLLGLHHGDYHALMKLSTFMDFPIPPGVEL
HHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHCCCCCCHHHHHHHHHHHCCCCCCCCEE
ALATMDGVLLLSTGSHVKELFSNPVNQSASDPSHDVVAARIQNPHHDWQIAVIEPIQQLV
EEEECCCEEEEECCHHHHHHHCCCCCCCCCCCCHHHEEEEECCCCCCEEEHHHHHHHHHH
GAVHRKEWLAIPVALLVSLSVSGLAILYLRRRRAPLARLRQAIQRCEFFVCYQPIVSLSD
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCEEEEEHHHHCCCC
GRCVGAEALVRWRQQDGTLILPDQFIPLAERSGLILPITDQVIAASMRELGPLLVADRSL
CCEECHHHHHHHHHCCCCEECCCCCCCHHCCCCEEEEEHHHHHHHHHHHCCCEEEECCEE
HIAINVSVKDIESGRLLDVLALALQDTGLYRKQLWIEATERSFMDARAAREHIVRLREAG
EEEEEEEEEECCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
YAVVIDDFGTGYSNLQYLQQLPLDALKIDKSFIDTVGRDVTNTAVASHIIDIAKELGMRT
CEEEEECCCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCHHH
IAEGVEREEQLVYLRARGVDMAQGWLFSSPLSVAEFVDYLSHNRSMHPDD
HHHHHCHHHHEEEEEECCCCHHCCCCCCCCCHHHHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8265357; 9278503 [H]