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The map label for this gene is aroE

Identifier: 182682139

GI number: 182682139

Start: 1791575

End: 1792423

Strand: Reverse

Name: aroE

Synonym: XfasM23_1617

Alternate gene names: 182682139

Gene position: 1792423-1791575 (Counterclockwise)

Preceding gene: 182682140

Following gene: 182682133

Centisome position: 70.69

GC content: 54.06

Gene sequence:

>849_bases
ATGCCTGTATCCCGTTTTGCTGTGTTTGGTCATCCCATTGCTCACTCGCTATCACCGCGCATCCATACCGAGTTTGGCCG
TCAGATGGGTGTCGTGCTGGACTATCTTGCATTTGATGTTGCGCCAGATGCGTTTCGTGTTTCGCTGGAGCATTTTGTTG
CCGAGGGTGGATGTGGTGCAAACGTGACTTTGCCTCTTAAGGAGGCTGCATTTGAGGTGTGCACAACTTTAAGTGCACGT
GCACGCCGTGCCGGTGCGGTCAATACGCTATCTCGCGTTGACGGTGTTTGGCATGGTGAGAATACCGATGGGACAGGTTT
AGTACGTAACTTGACGGAGCGGCATGGTTTGGATTTGCGTGGTCGCCGCGCTTTGCTGCTTGGCGCTGGTGGCGCTGCAC
GTGGTGTGGCTCCTGCATTGCTAGATGCCGGCATTACTGAGATGGTGATCGTTAACCGCTCCCCTGAGCGTGCCGATATG
CTGTGCGATGCGCTTGGTGAACCTGGCAAAGTCAGTGCACGCTACTGGGGTGACTTGGGTGATCTTGGAAATTTTGAGTT
AATCATTAACGCGACTTCGATCGGAAACACATCCGATATGCGCACTTTCTCTCTGCCGCGTTCGTTGTTGGACAGTATGA
CTGCGGCGGTAGACCTGAATTACGGTAGTGCAGCAGTCCCCTTCCTGGCCTGGGCGCATGCGGTTGAGACCCGCTATGCG
ATCGACGGGTTAGGTATGTTGGTTGAGCAAGCGGCTGAAAGTTTCTCTCTCTGGCACGGTCGGCGTCCGGATACTGATCC
AGTGTATACGGTATTACATTCAGAGTATGGCGTTCCTGGTCGGTCATGA

Upstream 100 bases:

>100_bases
GGAGTACACTCGTTTCTAGCGTCAGTCGGGGACATTGGATTCGCATTTTTCATGGGTCCTCATAGATTGGTGAATCATTT
AATTAGATTGGGAGCGTTGT

Downstream 100 bases:

>100_bases
CTGAAAAATAGGCGTGCTTTTTAGTACGGTGTACGGTCCTTTCTGTCCGTTACTGAGGTCGTTGCTGAGTAAGCCAACAT
GGTGTCTCAATGGAGTGGGT

Product: shikimate 5-dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 282; Mature: 281

Protein sequence:

>282_residues
MPVSRFAVFGHPIAHSLSPRIHTEFGRQMGVVLDYLAFDVAPDAFRVSLEHFVAEGGCGANVTLPLKEAAFEVCTTLSAR
ARRAGAVNTLSRVDGVWHGENTDGTGLVRNLTERHGLDLRGRRALLLGAGGAARGVAPALLDAGITEMVIVNRSPERADM
LCDALGEPGKVSARYWGDLGDLGNFELIINATSIGNTSDMRTFSLPRSLLDSMTAAVDLNYGSAAVPFLAWAHAVETRYA
IDGLGMLVEQAAESFSLWHGRRPDTDPVYTVLHSEYGVPGRS

Sequences:

>Translated_282_residues
MPVSRFAVFGHPIAHSLSPRIHTEFGRQMGVVLDYLAFDVAPDAFRVSLEHFVAEGGCGANVTLPLKEAAFEVCTTLSAR
ARRAGAVNTLSRVDGVWHGENTDGTGLVRNLTERHGLDLRGRRALLLGAGGAARGVAPALLDAGITEMVIVNRSPERADM
LCDALGEPGKVSARYWGDLGDLGNFELIINATSIGNTSDMRTFSLPRSLLDSMTAAVDLNYGSAAVPFLAWAHAVETRYA
IDGLGMLVEQAAESFSLWHGRRPDTDPVYTVLHSEYGVPGRS
>Mature_281_residues
PVSRFAVFGHPIAHSLSPRIHTEFGRQMGVVLDYLAFDVAPDAFRVSLEHFVAEGGCGANVTLPLKEAAFEVCTTLSARA
RRAGAVNTLSRVDGVWHGENTDGTGLVRNLTERHGLDLRGRRALLLGAGGAARGVAPALLDAGITEMVIVNRSPERADML
CDALGEPGKVSARYWGDLGDLGNFELIINATSIGNTSDMRTFSLPRSLLDSMTAAVDLNYGSAAVPFLAWAHAVETRYAI
DGLGMLVEQAAESFSLWHGRRPDTDPVYTVLHSEYGVPGRS

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; fourth step. [C]

COG id: COG0169

COG function: function code E; Shikimate 5-dehydrogenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the shikimate dehydrogenase family

Homologues:

Organism=Escherichia coli, GI1789675, Length=273, Percent_Identity=43.956043956044, Blast_Score=187, Evalue=6e-49,
Organism=Escherichia coli, GI1787983, Length=268, Percent_Identity=32.089552238806, Blast_Score=114, Evalue=5e-27,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): AROE_XYLF2 (B2I7C8)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001830299.1
- ProteinModelPortal:   B2I7C8
- SMR:   B2I7C8
- GeneID:   6202738
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_1617
- HOGENOM:   HBG553408
- OMA:   DQYVVFG
- ProtClustDB:   PRK00258
- GO:   GO:0005737
- HAMAP:   MF_00222
- InterPro:   IPR016040
- InterPro:   IPR011342
- InterPro:   IPR013708
- InterPro:   IPR022893
- InterPro:   IPR006151
- Gene3D:   G3DSA:3.40.50.720
- TIGRFAMs:   TIGR00507

Pfam domain/function: PF01488 Shikimate_DH; PF08501 Shikimate_dh_N

EC number: =1.1.1.25

Molecular weight: Translated: 30217; Mature: 30085

Theoretical pI: Translated: 6.03; Mature: 6.03

Prosite motif: NA

Important sites: ACT_SITE 67-67

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVSRFAVFGHPIAHSLSPRIHTEFGRQMGVVLDYLAFDVAPDAFRVSLEHFVAEGGCGA
CCCCHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
NVTLPLKEAAFEVCTTLSARARRAGAVNTLSRVDGVWHGENTDGTGLVRNLTERHGLDLR
CEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCC
GRRALLLGAGGAARGVAPALLDAGITEMVIVNRSPERADMLCDALGEPGKVSARYWGDLG
CCEEEEEECCCCHHCHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCCCCCHHCCCCCC
DLGNFELIINATSIGNTSDMRTFSLPRSLLDSMTAAVDLNYGSAAVPFLAWAHAVETRYA
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHH
IDGLGMLVEQAAESFSLWHGRRPDTDPVYTVLHSEYGVPGRS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEHHCCCCCCCC
>Mature Secondary Structure 
PVSRFAVFGHPIAHSLSPRIHTEFGRQMGVVLDYLAFDVAPDAFRVSLEHFVAEGGCGA
CCCHHHHHCCCHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCC
NVTLPLKEAAFEVCTTLSARARRAGAVNTLSRVDGVWHGENTDGTGLVRNLTERHGLDLR
CEEECHHHHHHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCCCCCCHHHHHHHHHCCCCCC
GRRALLLGAGGAARGVAPALLDAGITEMVIVNRSPERADMLCDALGEPGKVSARYWGDLG
CCEEEEEECCCCHHCHHHHHHHCCCEEEEEEECCCHHHHHHHHHCCCCCCCCHHCCCCCC
DLGNFELIINATSIGNTSDMRTFSLPRSLLDSMTAAVDLNYGSAAVPFLAWAHAVETRYA
CCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHH
IDGLGMLVEQAAESFSLWHGRRPDTDPVYTVLHSEYGVPGRS
HHHHHHHHHHHHHHHHHHCCCCCCCCHHHHEEHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA