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The map label for this gene is ccmE [H]

Identifier: 182682086

GI number: 182682086

Start: 1736623

End: 1737051

Strand: Direct

Name: ccmE [H]

Synonym: XfasM23_1564

Alternate gene names: 182682086

Gene position: 1736623-1737051 (Clockwise)

Preceding gene: 182682085

Following gene: 182682087

Centisome position: 68.49

GC content: 55.24

Gene sequence:

>429_bases
ATGCTGATACTGGCCGTCGGAACCGCAGCCACCCTCACTATCATGGCGTTGCGACACAACCTCACATACCTATACATGCC
CTCAGAAGTACTACGTGGCGACACGGCACAGCAAACACATTTCAGACTCGGCGGCATCGTAGAAAAAGGATCATTCCAAC
GCACCTCCGGCACCCTGAACACCCGCTTCATCGTCACCGATGGCAACGCACGCCTCCAAGTACGCTATGCCCGCATCCTC
CCAGACCTGTTCCGCGAAGGCCAAGCAATCGTCGCAACCGGACAGATGCAACATGGCACCTTCATTGCAGAAAACATCTT
GGCACGGCACAACGAAACCTATACACCGCGGCAACTGGCCAACAAAATGCAACCCACACCTACGCAACACACCCACCTAG
ATACCCCCATCGCCGAAACAACACCTTGA

Upstream 100 bases:

>100_bases
CACAGCGACTTGCACAGCATTTACACAAATGCCGCAACACACCTGCCATCAACAACACACCGACACAATGAATGCACGCC
GCCGCCTTTGGAGTGTCCTG

Downstream 100 bases:

>100_bases
GCAGTTCCGCACCACCACACCGGTATCAGATGATGCCTCCCCAGCCCCTGGAACCACACCCTGCACCCCTGCTCCTCCCA
TGAAGCCCCCCCGCCGCATC

Product: cytochrome c-type biogenesis protein CcmE

Products: NA

Alternate protein names: Cytochrome c maturation protein E; Heme chaperone CcmE [H]

Number of amino acids: Translated: 142; Mature: 142

Protein sequence:

>142_residues
MLILAVGTAATLTIMALRHNLTYLYMPSEVLRGDTAQQTHFRLGGIVEKGSFQRTSGTLNTRFIVTDGNARLQVRYARIL
PDLFREGQAIVATGQMQHGTFIAENILARHNETYTPRQLANKMQPTPTQHTHLDTPIAETTP

Sequences:

>Translated_142_residues
MLILAVGTAATLTIMALRHNLTYLYMPSEVLRGDTAQQTHFRLGGIVEKGSFQRTSGTLNTRFIVTDGNARLQVRYARIL
PDLFREGQAIVATGQMQHGTFIAENILARHNETYTPRQLANKMQPTPTQHTHLDTPIAETTP
>Mature_142_residues
MLILAVGTAATLTIMALRHNLTYLYMPSEVLRGDTAQQTHFRLGGIVEKGSFQRTSGTLNTRFIVTDGNARLQVRYARIL
PDLFREGQAIVATGQMQHGTFIAENILARHNETYTPRQLANKMQPTPTQHTHLDTPIAETTP

Specific function: Heme chaperone required for the biogenesis of c-type cytochromes. Transiently binds heme delivered by CcmC and transfers the heme to apo-cytochromes in a process facilitated by CcmF and CcmH [H]

COG id: COG2332

COG function: function code O; Cytochrome c-type biogenesis protein CcmE

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein; Periplasmic side (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CcmE/CycJ family [H]

Homologues:

Organism=Escherichia coli, GI1788525, Length=120, Percent_Identity=39.1666666666667, Blast_Score=94, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004329
- InterPro:   IPR012340 [H]

Pfam domain/function: PF03100 CcmE [H]

EC number: NA

Molecular weight: Translated: 15829; Mature: 15829

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLILAVGTAATLTIMALRHNLTYLYMPSEVLRGDTAQQTHFRLGGIVEKGSFQRTSGTLN
CEEEEECCHHHHHHHHHHHCCEEEEECHHHHCCCCCCCHHEEECCEEECCCCCCCCCCCE
TRFIVTDGNARLQVRYARILPDLFREGQAIVATGQMQHGTFIAENILARHNETYTPRQLA
EEEEEECCCCEEEEEHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHH
NKMQPTPTQHTHLDTPIAETTP
HCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLILAVGTAATLTIMALRHNLTYLYMPSEVLRGDTAQQTHFRLGGIVEKGSFQRTSGTLN
CEEEEECCHHHHHHHHHHHCCEEEEECHHHHCCCCCCCHHEEECCEEECCCCCCCCCCCE
TRFIVTDGNARLQVRYARILPDLFREGQAIVATGQMQHGTFIAENILARHNETYTPRQLA
EEEEEECCCCEEEEEHHHHHHHHHHCCCEEEEECCCCCCHHHHHHHHHHCCCCCCHHHHH
NKMQPTPTQHTHLDTPIAETTP
HCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]