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The map label for this gene is hlyD [H]

Identifier: 182682024

GI number: 182682024

Start: 1661987

End: 1663408

Strand: Direct

Name: hlyD [H]

Synonym: XfasM23_1500

Alternate gene names: 182682024

Gene position: 1661987-1663408 (Clockwise)

Preceding gene: 182682023

Following gene: 182682025

Centisome position: 65.54

GC content: 54.29

Gene sequence:

>1422_bases
ATGAAACACATGCTCCAAGGATGGCGCGACTTTCTTTCGCGTTACCTCCACGTCTTCCGTGCCGCCTGGTCGATTCGCGC
CCAACTAGAACCACCTCACCGCACCACCGATGAGCGCACCTTCCTACCCGCCCATCTAGAACTGACCGAAACCCCGGTCT
CCCCTACCGCATGCTGGAGCATGCGGATCATTATTGCCTGCTTCATCGTGACCCTACTGTGGGCCTGCTTCGGCAAAATT
GAAATTGTTGCCGTCGCCCCGGGGAAAATCGTCGTCGACTCACGCACCAAAGTACTCCAACCACTAGAGACCGCCGTAGT
ACGCCGTATCCTGGTCCGTGATGGCGAAAAAGTGAAAGCACACCAAGCACTGATCGAACTTGATGCCACCGCCACCGGCG
CCGAATACGCACAAGCTGAAGATGCCTTACTCAATGCCACATTGACCGCATTGCGCCTGCGCGCACTCTCCACCGCACTA
GAACGTGGCCAAACACCGCAACTCACCCATTCAGCAACCATCCCCGCTGATCGCATCGCCGCCGAACAAGCACTGACACT
GAGCCAATTCAATGCATACCAAGCCAAACGCCACAACCTACAAGCAACCATTGCCCAACGCCGCGCCGAACTACGGACAG
CCCAAGACACCATCGAACCATTGACCGAATCCGCACGCATCTCCAAAATGCGCTCCGCCGATTACGCCATACTCCTCAAA
GACAAATACGTCGGCCGTCACGACTACCTACTGCGTGAACAAGAACGCATCACCGCCGAACGCGACTTAGCAACCCAACG
CAACCGCATCCAAGAAATCCGCTCCGCCCTGAGCGCAGCCCAAGAAGAACTCAGCGTATTACAAGCCGACTTCCGCCAAC
AAACCCTGGATGACCTACGGAAAGCCGACGAACAGATCGGCCAATTGACACCACAACTGGCAAAAGCCAAACAACGTAAT
CGACTCATGACACTACGCTCCCCCGTTGAAGGCATCGTCCAGCAACTAGCCATCCACACCGTTGGTGGCGTCGTGACCCC
CGCACAACAACTCCTAGCCGTGGTCCCAGTACAAGAAACATTAGAAGTGGAAGCCACCGTCCTCAACAAAGACATCGGAT
TTTTACGTCCCGAACAACGCGTCACCGTCAAAATTGAAAGCTTCCCCTACACCCGCTACGGATACCTCACCGGCAAAATC
ATCAGCATCTCCCATGACGCCGCACAAGACGAAAAACTAGGCTTAGTCTTTCCCGTACGCATCCGTTTAGACAACACCAC
ACTCACTATTGATGGAACACAAATCAGAATGAGCGCAGGCATGGCATTAAGCGCCGAAATCAAAACAGGCAAACGCACCG
TTATTGATTACTTACTGAGCCCCCTAGAACAATATACCGACGAAGCATTGCGGGAACGATAA

Upstream 100 bases:

>100_bases
TTGATAAAGGGAAAATCGTAGAAAGCGGCTCCCACGAAACACTCCTCAACCGCAACAACGGTCATTACGCCCACCTCTAC
CGACTCCAACAAGGGACCAC

Downstream 100 bases:

>100_bases
ACCCCGCCATCAACATTGGCACTCCAATGCGCCTCCATCCCTTCCCCCAATGCCAATAACACCACCACCACATCACGCAA
ACACCTGCCAACGCACCTGC

Product: HlyD family type I secretion membrane fusion protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 473; Mature: 473

Protein sequence:

>473_residues
MKHMLQGWRDFLSRYLHVFRAAWSIRAQLEPPHRTTDERTFLPAHLELTETPVSPTACWSMRIIIACFIVTLLWACFGKI
EIVAVAPGKIVVDSRTKVLQPLETAVVRRILVRDGEKVKAHQALIELDATATGAEYAQAEDALLNATLTALRLRALSTAL
ERGQTPQLTHSATIPADRIAAEQALTLSQFNAYQAKRHNLQATIAQRRAELRTAQDTIEPLTESARISKMRSADYAILLK
DKYVGRHDYLLREQERITAERDLATQRNRIQEIRSALSAAQEELSVLQADFRQQTLDDLRKADEQIGQLTPQLAKAKQRN
RLMTLRSPVEGIVQQLAIHTVGGVVTPAQQLLAVVPVQETLEVEATVLNKDIGFLRPEQRVTVKIESFPYTRYGYLTGKI
ISISHDAAQDEKLGLVFPVRIRLDNTTLTIDGTQIRMSAGMALSAEIKTGKRTVIDYLLSPLEQYTDEALRER

Sequences:

>Translated_473_residues
MKHMLQGWRDFLSRYLHVFRAAWSIRAQLEPPHRTTDERTFLPAHLELTETPVSPTACWSMRIIIACFIVTLLWACFGKI
EIVAVAPGKIVVDSRTKVLQPLETAVVRRILVRDGEKVKAHQALIELDATATGAEYAQAEDALLNATLTALRLRALSTAL
ERGQTPQLTHSATIPADRIAAEQALTLSQFNAYQAKRHNLQATIAQRRAELRTAQDTIEPLTESARISKMRSADYAILLK
DKYVGRHDYLLREQERITAERDLATQRNRIQEIRSALSAAQEELSVLQADFRQQTLDDLRKADEQIGQLTPQLAKAKQRN
RLMTLRSPVEGIVQQLAIHTVGGVVTPAQQLLAVVPVQETLEVEATVLNKDIGFLRPEQRVTVKIESFPYTRYGYLTGKI
ISISHDAAQDEKLGLVFPVRIRLDNTTLTIDGTQIRMSAGMALSAEIKTGKRTVIDYLLSPLEQYTDEALRER
>Mature_473_residues
MKHMLQGWRDFLSRYLHVFRAAWSIRAQLEPPHRTTDERTFLPAHLELTETPVSPTACWSMRIIIACFIVTLLWACFGKI
EIVAVAPGKIVVDSRTKVLQPLETAVVRRILVRDGEKVKAHQALIELDATATGAEYAQAEDALLNATLTALRLRALSTAL
ERGQTPQLTHSATIPADRIAAEQALTLSQFNAYQAKRHNLQATIAQRRAELRTAQDTIEPLTESARISKMRSADYAILLK
DKYVGRHDYLLREQERITAERDLATQRNRIQEIRSALSAAQEELSVLQADFRQQTLDDLRKADEQIGQLTPQLAKAKQRN
RLMTLRSPVEGIVQQLAIHTVGGVVTPAQQLLAVVPVQETLEVEATVLNKDIGFLRPEQRVTVKIESFPYTRYGYLTGKI
ISISHDAAQDEKLGLVFPVRIRLDNTTLTIDGTQIRMSAGMALSAEIKTGKRTVIDYLLSPLEQYTDEALRER

Specific function: Involved in the transport of hemolysin A [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Single-pass type II membrane protein [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003997
- InterPro:   IPR006143
- InterPro:   IPR006144
- InterPro:   IPR010129 [H]

Pfam domain/function: PF00529 HlyD [H]

EC number: NA

Molecular weight: Translated: 53164; Mature: 53164

Theoretical pI: Translated: 9.20; Mature: 9.20

Prosite motif: PS00543 HLYD_FAMILY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.5 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKHMLQGWRDFLSRYLHVFRAAWSIRAQLEPPHRTTDERTFLPAHLELTETPVSPTACWS
CCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEECCCEEEEECCCCCCHHHHH
MRIIIACFIVTLLWACFGKIEIVAVAPGKIVVDSRTKVLQPLETAVVRRILVRDGEKVKA
HHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHH
HQALIELDATATGAEYAQAEDALLNATLTALRLRALSTALERGQTPQLTHSATIPADRIA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
AEQALTLSQFNAYQAKRHNLQATIAQRRAELRTAQDTIEPLTESARISKMRSADYAILLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DKYVGRHDYLLREQERITAERDLATQRNRIQEIRSALSAAQEELSVLQADFRQQTLDDLR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KADEQIGQLTPQLAKAKQRNRLMTLRSPVEGIVQQLAIHTVGGVVTPAQQLLAVVPVQET
HHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHH
LEVEATVLNKDIGFLRPEQRVTVKIESFPYTRYGYLTGKIISISHDAAQDEKLGLVFPVR
HHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEEEEECCCCCCCCCCEEEEEE
IRLDNTTLTIDGTQIRMSAGMALSAEIKTGKRTVIDYLLSPLEQYTDEALRER
EEECCEEEEEECCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKHMLQGWRDFLSRYLHVFRAAWSIRAQLEPPHRTTDERTFLPAHLELTETPVSPTACWS
CCHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCCCCCCEECCCEEEEECCCCCCHHHHH
MRIIIACFIVTLLWACFGKIEIVAVAPGKIVVDSRTKVLQPLETAVVRRILVRDGEKVKA
HHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCHHHHHHHHHHHHHHHHHCCCCHHHH
HQALIELDATATGAEYAQAEDALLNATLTALRLRALSTALERGQTPQLTHSATIPADRIA
HHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHH
AEQALTLSQFNAYQAKRHNLQATIAQRRAELRTAQDTIEPLTESARISKMRSADYAILLK
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEE
DKYVGRHDYLLREQERITAERDLATQRNRIQEIRSALSAAQEELSVLQADFRQQTLDDLR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
KADEQIGQLTPQLAKAKQRNRLMTLRSPVEGIVQQLAIHTVGGVVTPAQQLLAVVPVQET
HHHHHHHHCCHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHCCCHHH
LEVEATVLNKDIGFLRPEQRVTVKIESFPYTRYGYLTGKIISISHDAAQDEKLGLVFPVR
HHHHHHHHHCCCCCCCCCCEEEEEEECCCCEEEEEEEEEEEEEECCCCCCCCCCEEEEEE
IRLDNTTLTIDGTQIRMSAGMALSAEIKTGKRTVIDYLLSPLEQYTDEALRER
EEECCEEEEEECCEEEEECCCEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 3891743; 1495479 [H]