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The map label for this gene is serC [H]

Identifier: 182681968

GI number: 182681968

Start: 1593683

End: 1594765

Strand: Reverse

Name: serC [H]

Synonym: XfasM23_1443

Alternate gene names: 182681968

Gene position: 1594765-1593683 (Counterclockwise)

Preceding gene: 182681970

Following gene: 182681967

Centisome position: 62.89

GC content: 51.15

Gene sequence:

>1083_bases
ATGCGTATTTTTAATTTCAGCCCCGGTCCAGCGACCTTACCTGAACCAGTTTTGCGCCAAGCGCAGGCTGAAATGCTTGA
ATGGAATGCAGTGGGGGCTTCTGTGATGGAAATTAGTCACCGAAGTGCTGAATTTATAGCGCTGGCTAAAGGTATTGAGA
GCGACCTGCGTTGTTTGCTTGGAGTACCAGATGACTATGCAGTATTGTTCTTGTCCGGTGGTGCGACAACTCAGCAAGCG
TTGTTACCGCTTAATTTTGCCGCCCCAGGACAGACTGCTGATTATGTGGTCACCGGGCATTGGAGTAAGACCGCACTGAA
GCAAGCCAGCCCCTATGTGAATATTAACGTGGTGGCCGATGGGGAACGTGATGGTTTTCAGGATATTCCAAACCGTGCTG
GCTGGCGTTTGTCTAAAGATGCGGCGTATGTGCACATGACTGCGAACGAGACGATTCACGGCGTCGAGTTCCGCCAGACG
CCGGACGTTGGCGATGTGCCGTTGTTTGCCGACTTTAGCTCCTCGATTGCTGCTGATCTGATCGACGTATCCAAATACGA
TTTAATCTATGCTGGTGCGCAAAAGAACCTTGGTCCTGTCGGAATTTGCGTGGTGATCGTACGCCGTACTCTGCTTGAAC
GTACCGGTCAGCCGCGTGCTGATATTTTTACTTACGCCTCGCATGCCGAACGTGATTCGATGCTCAATACCCCGCCAACC
TTCAATTGGTACCTGCTTGGTCTTACCGTCAAGTGGATGCTTGCTGAGGGGGGAGTGCAGGAATTCGCGCGTCGTAATCA
GGCCAAGGCGCAATTGGTTTATCAGACGATTGATCAATCTGGCGGTTTTTATCGTAATGGAGTTGCTGCGGCAGTGCGTT
CGCGTATGAATATTCCGTTCTTTTTGCCGAATGTTGAGCAAGATGCTCGTTTCGCCGCCGAGGCTAAGGCCGCTGGTTTA
TTATCCTTGAAGGGGCATAAAGCGGTTGGTGGCATCCGTGCTTCCCTCTATAACGCCATGCCACTGGCTGGTGTGCAGGC
ATTAGTGGCATTTATGCATGATTTTCAACAGCGCTATGGTTGA

Upstream 100 bases:

>100_bases
CGAAAGAATGGATGCCGGTATTTTTAAGCATGTTATGTTGCTATCGAGCTGCTGCATACTGATTCAATAAAAATAAATTC
TTTCTAAAAGGTGGATGACG

Downstream 100 bases:

>100_bases
TTCTGGCGCCCATACCACACCGTTTGAGCGGTGATGACGATGAGGCATTTTTGCTCGTGACTACCAAGCTGGTTTCCAAA
TGACTAAGCCGGTTAATACT

Product: phosphoserine aminotransferase

Products: NA

Alternate protein names: Phosphohydroxythreonine aminotransferase; PSAT [H]

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MRIFNFSPGPATLPEPVLRQAQAEMLEWNAVGASVMEISHRSAEFIALAKGIESDLRCLLGVPDDYAVLFLSGGATTQQA
LLPLNFAAPGQTADYVVTGHWSKTALKQASPYVNINVVADGERDGFQDIPNRAGWRLSKDAAYVHMTANETIHGVEFRQT
PDVGDVPLFADFSSSIAADLIDVSKYDLIYAGAQKNLGPVGICVVIVRRTLLERTGQPRADIFTYASHAERDSMLNTPPT
FNWYLLGLTVKWMLAEGGVQEFARRNQAKAQLVYQTIDQSGGFYRNGVAAAVRSRMNIPFFLPNVEQDARFAAEAKAAGL
LSLKGHKAVGGIRASLYNAMPLAGVQALVAFMHDFQQRYG

Sequences:

>Translated_360_residues
MRIFNFSPGPATLPEPVLRQAQAEMLEWNAVGASVMEISHRSAEFIALAKGIESDLRCLLGVPDDYAVLFLSGGATTQQA
LLPLNFAAPGQTADYVVTGHWSKTALKQASPYVNINVVADGERDGFQDIPNRAGWRLSKDAAYVHMTANETIHGVEFRQT
PDVGDVPLFADFSSSIAADLIDVSKYDLIYAGAQKNLGPVGICVVIVRRTLLERTGQPRADIFTYASHAERDSMLNTPPT
FNWYLLGLTVKWMLAEGGVQEFARRNQAKAQLVYQTIDQSGGFYRNGVAAAVRSRMNIPFFLPNVEQDARFAAEAKAAGL
LSLKGHKAVGGIRASLYNAMPLAGVQALVAFMHDFQQRYG
>Mature_360_residues
MRIFNFSPGPATLPEPVLRQAQAEMLEWNAVGASVMEISHRSAEFIALAKGIESDLRCLLGVPDDYAVLFLSGGATTQQA
LLPLNFAAPGQTADYVVTGHWSKTALKQASPYVNINVVADGERDGFQDIPNRAGWRLSKDAAYVHMTANETIHGVEFRQT
PDVGDVPLFADFSSSIAADLIDVSKYDLIYAGAQKNLGPVGICVVIVRRTLLERTGQPRADIFTYASHAERDSMLNTPPT
FNWYLLGLTVKWMLAEGGVQEFARRNQAKAQLVYQTIDQSGGFYRNGVAAAVRSRMNIPFFLPNVEQDARFAAEAKAAGL
LSLKGHKAVGGIRASLYNAMPLAGVQALVAFMHDFQQRYG

Specific function: Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine [H]

COG id: COG1932

COG function: function code HE; Phosphoserine aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily [H]

Homologues:

Organism=Homo sapiens, GI17402893, Length=364, Percent_Identity=43.6813186813187, Blast_Score=305, Evalue=3e-83,
Organism=Homo sapiens, GI10863955, Length=360, Percent_Identity=38.8888888888889, Blast_Score=257, Evalue=1e-68,
Organism=Escherichia coli, GI1787136, Length=361, Percent_Identity=52.0775623268698, Blast_Score=360, Evalue=1e-101,
Organism=Caenorhabditis elegans, GI17506897, Length=363, Percent_Identity=40.495867768595, Blast_Score=284, Evalue=6e-77,
Organism=Saccharomyces cerevisiae, GI6324758, Length=384, Percent_Identity=35.4166666666667, Blast_Score=225, Evalue=9e-60,
Organism=Drosophila melanogaster, GI21356589, Length=361, Percent_Identity=44.0443213296399, Blast_Score=305, Evalue=3e-83,

Paralogues:

None

Copy number: 2500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000192
- InterPro:   IPR022278
- InterPro:   IPR003248
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00266 Aminotran_5 [H]

EC number: =2.6.1.52 [H]

Molecular weight: Translated: 39270; Mature: 39270

Theoretical pI: Translated: 6.89; Mature: 6.89

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIFNFSPGPATLPEPVLRQAQAEMLEWNAVGASVMEISHRSAEFIALAKGIESDLRCLL
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHHEEE
GVPDDYAVLFLSGGATTQQALLPLNFAAPGQTADYVVTGHWSKTALKQASPYVNINVVAD
CCCCCEEEEEEECCCCCCHHEEEEECCCCCCCCCEEEECCCCHHHHHHCCCEEEEEEEEC
GERDGFQDIPNRAGWRLSKDAAYVHMTANETIHGVEFRQTPDVGDVPLFADFSSSIAADL
CCCCCHHHCCCCCCCEEECCCEEEEEECCCEEECEEECCCCCCCCCCEEECCHHHHHHHH
IDVSKYDLIYAGAQKNLGPVGICVVIVRRTLLERTGQPRADIFTYASHAERDSMLNTPPT
HHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
FNWYLLGLTVKWMLAEGGVQEFARRNQAKAQLVYQTIDQSGGFYRNGVAAAVRSRMNIPF
CEEEEEEEEEEEHHHCCCHHHHHHHCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCE
FLPNVEQDARFAAEAKAAGLLSLKGHKAVGGIRASLYNAMPLAGVQALVAFMHDFQQRYG
EECCCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRIFNFSPGPATLPEPVLRQAQAEMLEWNAVGASVMEISHRSAEFIALAKGIESDLRCLL
CEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCHHHHHHHCCCHHHHHHHHCCCHHHHEEE
GVPDDYAVLFLSGGATTQQALLPLNFAAPGQTADYVVTGHWSKTALKQASPYVNINVVAD
CCCCCEEEEEEECCCCCCHHEEEEECCCCCCCCCEEEECCCCHHHHHHCCCEEEEEEEEC
GERDGFQDIPNRAGWRLSKDAAYVHMTANETIHGVEFRQTPDVGDVPLFADFSSSIAADL
CCCCCHHHCCCCCCCEEECCCEEEEEECCCEEECEEECCCCCCCCCCEEECCHHHHHHHH
IDVSKYDLIYAGAQKNLGPVGICVVIVRRTLLERTGQPRADIFTYASHAERDSMLNTPPT
HHCCCCEEEEECCCCCCCHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCCCCCCC
FNWYLLGLTVKWMLAEGGVQEFARRNQAKAQLVYQTIDQSGGFYRNGVAAAVRSRMNIPF
CEEEEEEEEEEEHHHCCCHHHHHHHCHHHHHHHHHHHHCCCCEEHHHHHHHHHHHCCCCE
FLPNVEQDARFAAEAKAAGLLSLKGHKAVGGIRASLYNAMPLAGVQALVAFMHDFQQRYG
EECCCCHHHHHHHHHHHCCEEEECCCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]