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The map label for this gene is fabF [H]

Identifier: 182681757

GI number: 182681757

Start: 1348101

End: 1349327

Strand: Direct

Name: fabF [H]

Synonym: XfasM23_1215

Alternate gene names: 182681757

Gene position: 1348101-1349327 (Clockwise)

Preceding gene: 182681755

Following gene: 182681758

Centisome position: 53.17

GC content: 55.26

Gene sequence:

>1227_bases
ATGAGTTCATTGCAAACTTCAGCACGTATGCCTCCTATCGCTATCACCGCCTTCACCGCTACCACTGCGGTAGGTCATGG
GCAAGCCGCACTGAATGAAGCACTACGCACACGTCGTAGTGGGCTACGCCGCAATGATTTTGGCGTACATCCACTTAAGT
GCTGGATCGGGGACGTGGGGGAGTTGGAAACCATGACCCTCCCTCAAGCATTGCATCCCTGGGAGTGCCGCAACAACCGG
CTGGCTTGGCTGGCACTGCAGCAAGATAACTTTTCCGAAGCAGTTGCAAACGCACGAACACGGCATGGAAAAACACAGAT
GGCGGTGATCATGGGCACCTCAACATCCAGCATCGGCGCAAGTGAAGAGGCGTATACCCGACTGGAATACGATGCCGAGG
GCGCACGCTTCCCAGACGATCTGCAAAGAGCCGTCATCCACTCTCCGCATTCACTAGGCAACTTTGTACAACACGCCACG
GACCTGTGCGGTCCCTGCGTTACCGTAGCGACCGCCTGCTCCTCTAGCGCCAAAGTATTCGCACAAGCAGCACGCCTAAT
TACCTCAGGCGTAGTGAGCGCCGCCCTAGTTGGTGGTGTGGACACCCTATGTGGCAGTGTGCTGTTTGGCTTCAACGCAC
TTCAATTAGTTTCACCAGAACCATGCCGTCCGTTTGATGTACATCGGGCCGGTCTGTCACTCGGTGAAGCAGGAGGCTTT
GCACTACTGGAAAGACTCGACCTAGCACCCGATGCGGATCTGTTGCTGTGTGGTTACGGCGAATCCAGCGATGCCCACCA
TATGTCCGCACCACACCCTGAAGGATTAGGAGCCCGCATGGCCATGCAAGAAGCACTGGCCAGAGCCAACGTAGATGCCA
GTGAAGTTGGCTATCTGAATTTGCATGGCACCGCCAGTCCTGCCAACGACAGCATTGAAGCTGTGGCAATAGCCGCACTG
TTCCCACCGACATTGCATGCCAGTTCGACCAAAGCCTGGACCGGCCACACCCTCGGTGCTTCTGGCATCGTTGAATCGAC
CATTGCACTCTTGGCTTTGCGAGGGAACATCCTGCCAGGCACCATGAATAGCGAACAGCTTGACCCAGTATGCGGACCGC
AGATCCGTTGCGAAAACGCACACACACCAATCCTGTACGCGATGAATAACTCTTTCGGTTTCGGAGGTAATAATTGCGCG
TTGTTATTCAAAAGAGCGGACGCATGA

Upstream 100 bases:

>100_bases
ATCCCAGAAGTACCACGCCTTAATATTGCAACCAACTGACAGTCTGGCTTGATAGCATCAATATACTAATTAAATATTCA
CGCCCAACGAATCTGTTCGA

Downstream 100 bases:

>100_bases
GCGTGCTAAGCGCCACTGTCGAAGGGATCGGCTTTTGGTACAACAGACTCCCCAGCTGGGCAGCCGCATGCCGCTTTGTT
GCTGGTGCTGCACCGCAGTC

Product: 3-oxoacyl-(acyl carrier protein) synthase I

Products: NA

Alternate protein names: 3-oxoacyl-[acyl-carrier-protein] synthase II; Beta-ketoacyl-ACP synthase II; KAS II [H]

Number of amino acids: Translated: 408; Mature: 407

Protein sequence:

>408_residues
MSSLQTSARMPPIAITAFTATTAVGHGQAALNEALRTRRSGLRRNDFGVHPLKCWIGDVGELETMTLPQALHPWECRNNR
LAWLALQQDNFSEAVANARTRHGKTQMAVIMGTSTSSIGASEEAYTRLEYDAEGARFPDDLQRAVIHSPHSLGNFVQHAT
DLCGPCVTVATACSSSAKVFAQAARLITSGVVSAALVGGVDTLCGSVLFGFNALQLVSPEPCRPFDVHRAGLSLGEAGGF
ALLERLDLAPDADLLLCGYGESSDAHHMSAPHPEGLGARMAMQEALARANVDASEVGYLNLHGTASPANDSIEAVAIAAL
FPPTLHASSTKAWTGHTLGASGIVESTIALLALRGNILPGTMNSEQLDPVCGPQIRCENAHTPILYAMNNSFGFGGNNCA
LLFKRADA

Sequences:

>Translated_408_residues
MSSLQTSARMPPIAITAFTATTAVGHGQAALNEALRTRRSGLRRNDFGVHPLKCWIGDVGELETMTLPQALHPWECRNNR
LAWLALQQDNFSEAVANARTRHGKTQMAVIMGTSTSSIGASEEAYTRLEYDAEGARFPDDLQRAVIHSPHSLGNFVQHAT
DLCGPCVTVATACSSSAKVFAQAARLITSGVVSAALVGGVDTLCGSVLFGFNALQLVSPEPCRPFDVHRAGLSLGEAGGF
ALLERLDLAPDADLLLCGYGESSDAHHMSAPHPEGLGARMAMQEALARANVDASEVGYLNLHGTASPANDSIEAVAIAAL
FPPTLHASSTKAWTGHTLGASGIVESTIALLALRGNILPGTMNSEQLDPVCGPQIRCENAHTPILYAMNNSFGFGGNNCA
LLFKRADA
>Mature_407_residues
SSLQTSARMPPIAITAFTATTAVGHGQAALNEALRTRRSGLRRNDFGVHPLKCWIGDVGELETMTLPQALHPWECRNNRL
AWLALQQDNFSEAVANARTRHGKTQMAVIMGTSTSSIGASEEAYTRLEYDAEGARFPDDLQRAVIHSPHSLGNFVQHATD
LCGPCVTVATACSSSAKVFAQAARLITSGVVSAALVGGVDTLCGSVLFGFNALQLVSPEPCRPFDVHRAGLSLGEAGGFA
LLERLDLAPDADLLLCGYGESSDAHHMSAPHPEGLGARMAMQEALARANVDASEVGYLNLHGTASPANDSIEAVAIAALF
PPTLHASSTKAWTGHTLGASGIVESTIALLALRGNILPGTMNSEQLDPVCGPQIRCENAHTPILYAMNNSFGFGGNNCAL
LFKRADA

Specific function: Catalyzes the condensation reaction of fatty acid synthesis by the addition to an acyl acceptor of two carbons from malonyl-ACP [H]

COG id: COG0304

COG function: function code IQ; 3-oxoacyl-(acyl-carrier-protein) synthase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the beta-ketoacyl-ACP synthases family [H]

Homologues:

Organism=Homo sapiens, GI8923559, Length=260, Percent_Identity=36.1538461538462, Blast_Score=125, Evalue=9e-29,
Organism=Homo sapiens, GI223972627, Length=145, Percent_Identity=40.6896551724138, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI41872631, Length=266, Percent_Identity=27.0676691729323, Blast_Score=67, Evalue=2e-11,
Organism=Escherichia coli, GI1787337, Length=261, Percent_Identity=37.1647509578544, Blast_Score=145, Evalue=5e-36,
Organism=Escherichia coli, GI1788663, Length=422, Percent_Identity=29.1469194312796, Blast_Score=124, Evalue=1e-29,
Organism=Caenorhabditis elegans, GI71983541, Length=412, Percent_Identity=28.8834951456311, Blast_Score=144, Evalue=7e-35,
Organism=Caenorhabditis elegans, GI71983535, Length=258, Percent_Identity=33.7209302325581, Blast_Score=140, Evalue=1e-33,
Organism=Caenorhabditis elegans, GI212642053, Length=270, Percent_Identity=27.7777777777778, Blast_Score=81, Evalue=8e-16,
Organism=Caenorhabditis elegans, GI17550940, Length=286, Percent_Identity=26.5734265734266, Blast_Score=78, Evalue=8e-15,
Organism=Saccharomyces cerevisiae, GI6320904, Length=317, Percent_Identity=33.7539432176656, Blast_Score=127, Evalue=4e-30,
Organism=Drosophila melanogaster, GI24644341, Length=260, Percent_Identity=36.5384615384615, Blast_Score=132, Evalue=6e-31,
Organism=Drosophila melanogaster, GI221330659, Length=266, Percent_Identity=24.812030075188, Blast_Score=77, Evalue=2e-14,
Organism=Drosophila melanogaster, GI19920632, Length=266, Percent_Identity=24.812030075188, Blast_Score=77, Evalue=3e-14,
Organism=Drosophila melanogaster, GI24581345, Length=267, Percent_Identity=24.7191011235955, Blast_Score=75, Evalue=9e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017568
- InterPro:   IPR000794
- InterPro:   IPR018201
- InterPro:   IPR014031
- InterPro:   IPR014030
- InterPro:   IPR016039
- InterPro:   IPR016038 [H]

Pfam domain/function: PF00109 ketoacyl-synt; PF02801 Ketoacyl-synt_C [H]

EC number: =2.3.1.179 [H]

Molecular weight: Translated: 42951; Mature: 42820

Theoretical pI: Translated: 6.22; Mature: 6.22

Prosite motif: PS00606 B_KETOACYL_SYNTHASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.7 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
2.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSLQTSARMPPIAITAFTATTAVGHGQAALNEALRTRRSGLRRNDFGVHPLKCWIGDVG
CCCCCCCCCCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCC
ELETMTLPQALHPWECRNNRLAWLALQQDNFSEAVANARTRHGKTQMAVIMGTSTSSIGA
CCEEEECCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCC
SEEAYTRLEYDAEGARFPDDLQRAVIHSPHSLGNFVQHATDLCGPCVTVATACSSSAKVF
CHHHHEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AQAARLITSGVVSAALVGGVDTLCGSVLFGFNALQLVSPEPCRPFDVHRAGLSLGEAGGF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHCCCCCCCCCH
ALLERLDLAPDADLLLCGYGESSDAHHMSAPHPEGLGARMAMQEALARANVDASEVGYLN
HHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCEEE
LHGTASPANDSIEAVAIAALFPPTLHASSTKAWTGHTLGASGIVESTIALLALRGNILPG
ECCCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TMNSEQLDPVCGPQIRCENAHTPILYAMNNSFGFGGNNCALLFKRADA
CCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCEEEEEEECCC
>Mature Secondary Structure 
SSLQTSARMPPIAITAFTATTAVGHGQAALNEALRTRRSGLRRNDFGVHPLKCWIGDVG
CCCCCCCCCCCEEEEEEEHHHHCCCCHHHHHHHHHHHHHCCCCCCCCCCHHHHHCCCCC
ELETMTLPQALHPWECRNNRLAWLALQQDNFSEAVANARTRHGKTQMAVIMGTSTSSIGA
CCEEEECCCCCCCCCCCCCEEEEEEEECCCHHHHHHHHHHHCCCEEEEEEEECCCCCCCC
SEEAYTRLEYDAEGARFPDDLQRAVIHSPHSLGNFVQHATDLCGPCVTVATACSSSAKVF
CHHHHEEEEECCCCCCCHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHH
AQAARLITSGVVSAALVGGVDTLCGSVLFGFNALQLVSPEPCRPFDVHRAGLSLGEAGGF
HHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCCEEECCCCCCCCCHHHHHCCCCCCCCCH
ALLERLDLAPDADLLLCGYGESSDAHHMSAPHPEGLGARMAMQEALARANVDASEVGYLN
HHHHHHCCCCCCCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCHHHCCEEE
LHGTASPANDSIEAVAIAALFPPTLHASSTKAWTGHTLGASGIVESTIALLALRGNILPG
ECCCCCCCCCCHHHEEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCCCC
TMNSEQLDPVCGPQIRCENAHTPILYAMNNSFGFGGNNCALLFKRADA
CCCCCCCCCCCCCCEEECCCCCCEEEEECCCCCCCCCCEEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]