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The map label for this gene is mprF [H]

Identifier: 182681755

GI number: 182681755

Start: 1341446

End: 1344037

Strand: Direct

Name: mprF [H]

Synonym: XfasM23_1213

Alternate gene names: 182681755

Gene position: 1341446-1344037 (Clockwise)

Preceding gene: 182681754

Following gene: 182681757

Centisome position: 52.9

GC content: 51.74

Gene sequence:

>2592_bases
ATGACAGATAACAGCAGCACCCACAACATACACCGCCAATCTGGCTGGCGCCGTGCCATACCGGTATTCATCAGTCTGCT
CATTCTCGGCATGGCGTTACATGCGTTGTCTGGCCACTTTACTAATCATGGCTATCACCAGATCCGCTTAGCATTCAAAG
CATTTACCACTTGGCAAATCGTACTGACCCTAGTACTTGGGCTGTGTAGCTACGCTTGCTTGGTAGGCTTCGATTGGATC
GGTTTACAACGTACCGGCAAACGTCCACATCCTGCACGGGTGGCGATTACCGCCTTCCTCGCCCACACAATCGGCCAGAC
ATTGGGCTTTGCCGCACTGACAGGTGGTGCAGTACGGTTACGTGGCTACAGCAAAGTGGGACTGAGCCTCATTGAAATCG
GCCAAATAGTATTGATGAGCACCTTGGGCTTCATATTTGGTGCTTGGGTACTACTGGGCTTGGCATTAGCACTCGAACCC
GCCACAGCGACACCAATACTGCCACTGGACACACTAGGGATCCGCAGCACAGGTATTGCCTTACTCGCCGCATTCCTAGT
GATGTTGTGGCTTGTTAACAGCAACGGTCGAGAGTTCGGCATCGGTCGGCAACGCTTTTGGATACCGGATAGACGCACCG
TGCTAGGCGTCACTGCACTCAGTATCGTCGAGTTAGGTCTAGCTTGCGCCGCATTCTATGTGCTATTGCCATCAGAAGCG
AACACAAGCTTCTTCGGCTTCATCGGCCTATGGCTAGTTGCTGTTGTCGCCGGGTTGATATCCACAGTGCCGGCTGGACT
GGGTGTCTTCGAATGGAGCATGCTCAAACTTCTGCCTCACACTCCGCCTAGCGTAGTACTGGCAGCAGCGTTGGCCTATC
GCATTACCTATTACGTCTTGCCTACCCTCATTGCGCTGACGATGGCTGCAAGTAGCGGTCTGCGCCAACCAATGCGAGTC
AGCGCCGGCACCGCAATTGCAATCTGGAACACCGTACGCCCCTGGATCCCCCAAATCATCGCACTAGCCGTTTTTGCAAT
CGGTACGATACTGCTGGTTGATGGCACCTTACCGACACCAAAATCACGACAAGAGGTCGCCCCCCTCCCCCTCATTGAGA
CTTCACATTTACTAGTCAGTCTCGGTGGCATTGTCCTATTACTCATTGGCCAAGGGCTGCAACGACGTAGCCACTCAGCT
TGGCTGCTAGCCTTAGGCATCTGCATATTACTCCCACCACTGGCGCTGTTACGTGGTAGCCACTACTCGGTTTCACTGTG
GGCTGGCTTGACCGCAGTAACACTTTGGATGGCGCGGCGCGAGTTTTACCGCCAGAGTGCCCTGCTCGACGAAGCTTGGT
CGTGGCGCTGGTTGAGCAATATAGGCATCGTCATAGTAAGCACCTTCTGGCTAGTGTTCTTCGTCTATAGCCACGTTGAG
TACAGCAACGACTTGTGGTGGGAATTTGCAACCTCTGGAAACGCGCCGCGCGCACTACGTGCATTGTTATTGATATGTGT
TTGCCTCATCGTGTTCGGTATGGCGCGTTTACTGCATAACGCCCGGCGACCCTTCACACCAGCCAGTGAAGCTGAGTTGC
AAGCCTTATTGCCGATACTTGCCAATAACAAAGACACAAAAGCCTGTCTGGCCATGACCGGGGATAAGGCGTTACTACAC
GACCCACAGAAACACAGCTTCATAATGATGCAGCGCTACGGCGGTTCACTGATCGCAATGGGTGACCCCATTGGGCCACC
TGAAGCAGCGATCCAACTGATCTGGCGCTTCCGTGAAGTCGCTGACCGGCTTGGATTACGCCCAGTGTTCTATCAAGTCG
GCGACAACTATTGGCAAAATTACTTGGATCTAGGCATGACTATGGTCAAGATTGGAGAAGAAGCAATCATTGACCTTGAA
AAATTCAGCCTCGAAGGATCTGCTAACGCCGAAATGCGGCAAGCATTCAACAAAGGGAAACGACTGGGATTGCGTTTTCG
TATTCTTTCGGAAGAAGAAGTCAGACCACTGATGGATAGGCTCCGTCAGATCTCTGACGAATGGCTGGAAGAAAAGGGCA
GCGAAGAGAAAAGTTTTTCTCTAGGAAATTTCGATCCCATCTACCTATATCGCTTTCCAATCGCGGTAATTGAGCATGAA
GCACAACAGAAAATCATCGCCTTTGCAAACATTTTAAAAGCACAACCAGGCAGCGAGCTATCAATAGACTTGATGCGATA
TAGCCAAGACGCACCTAATGGCACGATGGACTTTTTGTTCGTAACCATGTTCCTGTGGGGAAAAGAGCAAGGTTTCCAAC
GGTTTTCTTTAGGAATGGCACCACTATCAGGCTTAGCGCAACATCATTTAGCGGGGCGCTGGAATCGGTTCGCCAACCTA
ATCGCACGGCATGGCGAACGCTTCTACGGTTTCAGTGGTCTACGTCGCTTCAAAGCCAAATTCTCACCAAATTGGTGTCC
CCGCTACTTAGCGGCACCTGGGGGTATGCACCTTTTTGCAGCATTACTTGATGTCACCAGGCTGATTTCCATCAGCCCCA
AACGCCGCGAGGGCAATTGCGATCAAATTTAA

Upstream 100 bases:

>100_bases
ACTTTGCCCCTCAATCTGTCGCCCTGTCGCCCTTGAGGCGTCGCCTACTGTTAAGTAACAGTCTGGAAATGGATATGTTC
TCTTGAGGAATGACCGACTC

Downstream 100 bases:

>100_bases
AGTGTGCGGTGCACTTAACACCAATACAAACTTTTAGCCTAATCGCTCTGAATACAGATAACAGAGTGGCACACAAACAA
TGAAAAAAGAGCATTTATGC

Product: hypothetical protein

Products: NA

Alternate protein names: Lysylphosphatidylglycerol synthase; LPG synthase [H]

Number of amino acids: Translated: 863; Mature: 862

Protein sequence:

>863_residues
MTDNSSTHNIHRQSGWRRAIPVFISLLILGMALHALSGHFTNHGYHQIRLAFKAFTTWQIVLTLVLGLCSYACLVGFDWI
GLQRTGKRPHPARVAITAFLAHTIGQTLGFAALTGGAVRLRGYSKVGLSLIEIGQIVLMSTLGFIFGAWVLLGLALALEP
ATATPILPLDTLGIRSTGIALLAAFLVMLWLVNSNGREFGIGRQRFWIPDRRTVLGVTALSIVELGLACAAFYVLLPSEA
NTSFFGFIGLWLVAVVAGLISTVPAGLGVFEWSMLKLLPHTPPSVVLAAALAYRITYYVLPTLIALTMAASSGLRQPMRV
SAGTAIAIWNTVRPWIPQIIALAVFAIGTILLVDGTLPTPKSRQEVAPLPLIETSHLLVSLGGIVLLLIGQGLQRRSHSA
WLLALGICILLPPLALLRGSHYSVSLWAGLTAVTLWMARREFYRQSALLDEAWSWRWLSNIGIVIVSTFWLVFFVYSHVE
YSNDLWWEFATSGNAPRALRALLLICVCLIVFGMARLLHNARRPFTPASEAELQALLPILANNKDTKACLAMTGDKALLH
DPQKHSFIMMQRYGGSLIAMGDPIGPPEAAIQLIWRFREVADRLGLRPVFYQVGDNYWQNYLDLGMTMVKIGEEAIIDLE
KFSLEGSANAEMRQAFNKGKRLGLRFRILSEEEVRPLMDRLRQISDEWLEEKGSEEKSFSLGNFDPIYLYRFPIAVIEHE
AQQKIIAFANILKAQPGSELSIDLMRYSQDAPNGTMDFLFVTMFLWGKEQGFQRFSLGMAPLSGLAQHHLAGRWNRFANL
IARHGERFYGFSGLRRFKAKFSPNWCPRYLAAPGGMHLFAALLDVTRLISISPKRREGNCDQI

Sequences:

>Translated_863_residues
MTDNSSTHNIHRQSGWRRAIPVFISLLILGMALHALSGHFTNHGYHQIRLAFKAFTTWQIVLTLVLGLCSYACLVGFDWI
GLQRTGKRPHPARVAITAFLAHTIGQTLGFAALTGGAVRLRGYSKVGLSLIEIGQIVLMSTLGFIFGAWVLLGLALALEP
ATATPILPLDTLGIRSTGIALLAAFLVMLWLVNSNGREFGIGRQRFWIPDRRTVLGVTALSIVELGLACAAFYVLLPSEA
NTSFFGFIGLWLVAVVAGLISTVPAGLGVFEWSMLKLLPHTPPSVVLAAALAYRITYYVLPTLIALTMAASSGLRQPMRV
SAGTAIAIWNTVRPWIPQIIALAVFAIGTILLVDGTLPTPKSRQEVAPLPLIETSHLLVSLGGIVLLLIGQGLQRRSHSA
WLLALGICILLPPLALLRGSHYSVSLWAGLTAVTLWMARREFYRQSALLDEAWSWRWLSNIGIVIVSTFWLVFFVYSHVE
YSNDLWWEFATSGNAPRALRALLLICVCLIVFGMARLLHNARRPFTPASEAELQALLPILANNKDTKACLAMTGDKALLH
DPQKHSFIMMQRYGGSLIAMGDPIGPPEAAIQLIWRFREVADRLGLRPVFYQVGDNYWQNYLDLGMTMVKIGEEAIIDLE
KFSLEGSANAEMRQAFNKGKRLGLRFRILSEEEVRPLMDRLRQISDEWLEEKGSEEKSFSLGNFDPIYLYRFPIAVIEHE
AQQKIIAFANILKAQPGSELSIDLMRYSQDAPNGTMDFLFVTMFLWGKEQGFQRFSLGMAPLSGLAQHHLAGRWNRFANL
IARHGERFYGFSGLRRFKAKFSPNWCPRYLAAPGGMHLFAALLDVTRLISISPKRREGNCDQI
>Mature_862_residues
TDNSSTHNIHRQSGWRRAIPVFISLLILGMALHALSGHFTNHGYHQIRLAFKAFTTWQIVLTLVLGLCSYACLVGFDWIG
LQRTGKRPHPARVAITAFLAHTIGQTLGFAALTGGAVRLRGYSKVGLSLIEIGQIVLMSTLGFIFGAWVLLGLALALEPA
TATPILPLDTLGIRSTGIALLAAFLVMLWLVNSNGREFGIGRQRFWIPDRRTVLGVTALSIVELGLACAAFYVLLPSEAN
TSFFGFIGLWLVAVVAGLISTVPAGLGVFEWSMLKLLPHTPPSVVLAAALAYRITYYVLPTLIALTMAASSGLRQPMRVS
AGTAIAIWNTVRPWIPQIIALAVFAIGTILLVDGTLPTPKSRQEVAPLPLIETSHLLVSLGGIVLLLIGQGLQRRSHSAW
LLALGICILLPPLALLRGSHYSVSLWAGLTAVTLWMARREFYRQSALLDEAWSWRWLSNIGIVIVSTFWLVFFVYSHVEY
SNDLWWEFATSGNAPRALRALLLICVCLIVFGMARLLHNARRPFTPASEAELQALLPILANNKDTKACLAMTGDKALLHD
PQKHSFIMMQRYGGSLIAMGDPIGPPEAAIQLIWRFREVADRLGLRPVFYQVGDNYWQNYLDLGMTMVKIGEEAIIDLEK
FSLEGSANAEMRQAFNKGKRLGLRFRILSEEEVRPLMDRLRQISDEWLEEKGSEEKSFSLGNFDPIYLYRFPIAVIEHEA
QQKIIAFANILKAQPGSELSIDLMRYSQDAPNGTMDFLFVTMFLWGKEQGFQRFSLGMAPLSGLAQHHLAGRWNRFANLI
ARHGERFYGFSGLRRFKAKFSPNWCPRYLAAPGGMHLFAALLDVTRLISISPKRREGNCDQI

Specific function: Catalyzes the transfer of a lysyl group from L-lysyl- tRNA(Lys) to membrane-bound phosphatidylglycerol (PG), which produces lysylphosphatidylglycerol (LPG), one of the components of the bacterial membrane with a positive net charge. LPG synthesis contribu

COG id: COG2898

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the LPG synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787006, Length=241, Percent_Identity=28.2157676348548, Blast_Score=74, Evalue=5e-14,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016181
- InterPro:   IPR022791 [H]

Pfam domain/function: PF03706 UPF0104 [H]

EC number: =2.3.2.3 [H]

Molecular weight: Translated: 95799; Mature: 95668

Theoretical pI: Translated: 9.91; Mature: 9.91

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDNSSTHNIHRQSGWRRAIPVFISLLILGMALHALSGHFTNHGYHQIRLAFKAFTTWQI
CCCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VLTLVLGLCSYACLVGFDWIGLQRTGKRPHPARVAITAFLAHTIGQTLGFAALTGGAVRL
HHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
RGYSKVGLSLIEIGQIVLMSTLGFIFGAWVLLGLALALEPATATPILPLDTLGIRSTGIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
LLAAFLVMLWLVNSNGREFGIGRQRFWIPDRRTVLGVTALSIVELGLACAAFYVLLPSEA
HHHHHHHHHHHHCCCCCEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NTSFFGFIGLWLVAVVAGLISTVPAGLGVFEWSMLKLLPHTPPSVVLAAALAYRITYYVL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
PTLIALTMAASSGLRQPMRVSAGTAIAIWNTVRPWIPQIIALAVFAIGTILLVDGTLPTP
HHHHHHHHHHHHCCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
KSRQEVAPLPLIETSHLLVSLGGIVLLLIGQGLQRRSHSAWLLALGICILLPPLALLRGS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCC
HYSVSLWAGLTAVTLWMARREFYRQSALLDEAWSWRWLSNIGIVIVSTFWLVFFVYSHVE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHH
YSNDLWWEFATSGNAPRALRALLLICVCLIVFGMARLLHNARRPFTPASEAELQALLPIL
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
ANNKDTKACLAMTGDKALLHDPQKHSFIMMQRYGGSLIAMGDPIGPPEAAIQLIWRFREV
CCCCCCCEEEEECCCHHHHCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHH
ADRLGLRPVFYQVGDNYWQNYLDLGMTMVKIGEEAIIDLEKFSLEGSANAEMRQAFNKGK
HHHHCCCHHHHHHCHHHHHHHHHHHHHHHHCCHHHHEEHHHHCCCCCCCHHHHHHHHHCC
RLGLRFRILSEEEVRPLMDRLRQISDEWLEEKGSEEKSFSLGNFDPIYLYRFPIAVIEHE
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHHHH
AQQKIIAFANILKAQPGSELSIDLMRYSQDAPNGTMDFLFVTMFLWGKEQGFQRFSLGMA
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCHH
PLSGLAQHHLAGRWNRFANLIARHGERFYGFSGLRRFKAKFSPNWCPRYLAAPGGMHLFA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHCCCCCCCHHHCCCCHHHHHH
ALLDVTRLISISPKRREGNCDQI
HHHHHHHHHHCCCCCCCCCCCCC
>Mature Secondary Structure 
TDNSSTHNIHRQSGWRRAIPVFISLLILGMALHALSGHFTNHGYHQIRLAFKAFTTWQI
CCCCCCCCCHHHCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHH
VLTLVLGLCSYACLVGFDWIGLQRTGKRPHPARVAITAFLAHTIGQTLGFAALTGGAVRL
HHHHHHHHHHHHHHHCCHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEE
RGYSKVGLSLIEIGQIVLMSTLGFIFGAWVLLGLALALEPATATPILPLDTLGIRSTGIA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHH
LLAAFLVMLWLVNSNGREFGIGRQRFWIPDRRTVLGVTALSIVELGLACAAFYVLLPSEA
HHHHHHHHHHHHCCCCCEECCCCCEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCC
NTSFFGFIGLWLVAVVAGLISTVPAGLGVFEWSMLKLLPHTPPSVVLAAALAYRITYYVL
CCHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHH
PTLIALTMAASSGLRQPMRVSAGTAIAIWNTVRPWIPQIIALAVFAIGTILLVDGTLPTP
HHHHHHHHHHHHCCCCCCEECCCCEEEEHHHHHHHHHHHHHHHHHHHHHHEEECCCCCCC
KSRQEVAPLPLIETSHLLVSLGGIVLLLIGQGLQRRSHSAWLLALGICILLPPLALLRGS
CCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCHHHCCCCHHHHHHHHHHHHHHHHHHCCC
HYSVSLWAGLTAVTLWMARREFYRQSALLDEAWSWRWLSNIGIVIVSTFWLVFFVYSHVE
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHCCHHHHHHHHHHHHHHHHHH
YSNDLWWEFATSGNAPRALRALLLICVCLIVFGMARLLHNARRPFTPASEAELQALLPIL
CCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHH
ANNKDTKACLAMTGDKALLHDPQKHSFIMMQRYGGSLIAMGDPIGPPEAAIQLIWRFREV
CCCCCCCEEEEECCCHHHHCCCCCCCEEEEEECCCEEEECCCCCCCHHHHHHHHHHHHHH
ADRLGLRPVFYQVGDNYWQNYLDLGMTMVKIGEEAIIDLEKFSLEGSANAEMRQAFNKGK
HHHHCCCHHHHHHCHHHHHHHHHHHHHHHHCCHHHHEEHHHHCCCCCCCHHHHHHHHHCC
RLGLRFRILSEEEVRPLMDRLRQISDEWLEEKGSEEKSFSLGNFDPIYLYRFPIAVIEHE
CCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEECHHHHHHHH
AQQKIIAFANILKAQPGSELSIDLMRYSQDAPNGTMDFLFVTMFLWGKEQGFQRFSLGMA
HHHHHHHHHHHHHCCCCCCCCHHHHHHCCCCCCCHHHHHHHHHHHHCCCCCHHHHHCCHH
PLSGLAQHHLAGRWNRFANLIARHGERFYGFSGLRRFKAKFSPNWCPRYLAAPGGMHLFA
HHHHHHHHHHHHHHHHHHHHHHHCCCHHHCHHHHHHHHHHCCCCCCCHHHCCCCHHHHHH
ALLDVTRLISISPKRREGNCDQI
HHHHHHHHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8946165; 9384377 [H]