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The map label for this gene is trpR

Identifier: 182681472

GI number: 182681472

Start: 1093371

End: 1093649

Strand: Direct

Name: trpR

Synonym: XfasM23_0924

Alternate gene names: 182681472

Gene position: 1093371-1093649 (Clockwise)

Preceding gene: 182681467

Following gene: 182681477

Centisome position: 43.12

GC content: 34.77

Gene sequence:

>279_bases
ATGTCACGTGAACAAGCATTTGAAATGCTGATTAAAATTTTGTGTAAGACAGATTCTACTGACGATATGAAACTCATTTT
GGAGTGCATTCTAACTAGGAGCGAAATGGAGGACCTCATTGACCGTATTCGTATCTATAATGAGCTTCTAAACACTAGCA
ACTCACAACGTGAAGTTGCCAGTAAACTAGGAGTAAGCATTACAAAGATAACAAGAGGAGCAGCCAATCTTCAGGATAAT
AATATAAAAGATTTTCTTAGAAAAAAAATAAGCTACTAA

Upstream 100 bases:

>100_bases
ACGATATGATTATAATATCTTTAGAATAATTAGCTTTATCTATTTTTTTAAAGCTATTAAAAAATAGATTTTTATATTTA
TATCTCAGAAGGTGTCGATT

Downstream 100 bases:

>100_bases
CTTATCGGTTTGAGGTGATACAACATTGGTAAGTTAATGACGATACGTGATGCTGCTCATGAGTTTTTAAGATAATTTAT
CTTAAGTCTATAAATAAAGA

Product: Trp operon repressor

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 92; Mature: 91

Protein sequence:

>92_residues
MSREQAFEMLIKILCKTDSTDDMKLILECILTRSEMEDLIDRIRIYNELLNTSNSQREVASKLGVSITKITRGAANLQDN
NIKDFLRKKISY

Sequences:

>Translated_92_residues
MSREQAFEMLIKILCKTDSTDDMKLILECILTRSEMEDLIDRIRIYNELLNTSNSQREVASKLGVSITKITRGAANLQDN
NIKDFLRKKISY
>Mature_91_residues
SREQAFEMLIKILCKTDSTDDMKLILECILTRSEMEDLIDRIRIYNELLNTSNSQREVASKLGVSITKITRGAANLQDNN
IKDFLRKKISY

Specific function: This protein is an aporepressor. When complexed with L- tryptophan it binds the operator region of the trp operon and prevents the initiation of transcription

COG id: COG2973

COG function: function code K; Trp operon repressor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the trpR family

Homologues:

None

Paralogues:

None

Copy number: 250-750 50-300 [C]

Swissprot (AC and ID): TRPR_XYLF2 (B2I4R3)

Other databases:

- EMBL:   CP001011
- RefSeq:   YP_001829632.1
- ProteinModelPortal:   B2I4R3
- SMR:   B2I4R3
- GeneID:   6203834
- GenomeReviews:   CP001011_GR
- KEGG:   xfn:XfasM23_0924
- HOGENOM:   HBG270551
- OMA:   RILLTKE
- ProtClustDB:   CLSK236488
- GO:   GO:0005737
- HAMAP:   MF_00475
- InterPro:   IPR000831
- InterPro:   IPR013335
- InterPro:   IPR010921
- Gene3D:   G3DSA:1.10.1270.10
- PIRSF:   PIRSF003196
- ProDom:   PD012582
- TIGRFAMs:   TIGR01321

Pfam domain/function: PF01371 Trp_repressor; SSF48295 Trp_repress_rep

EC number: NA

Molecular weight: Translated: 10657; Mature: 10525

Theoretical pI: Translated: 8.20; Mature: 8.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.2 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
6.5 %Cys+Met (Translated Protein)
2.2 %Cys     (Mature Protein)
3.3 %Met     (Mature Protein)
5.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSREQAFEMLIKILCKTDSTDDMKLILECILTRSEMEDLIDRIRIYNELLNTSNSQREVA
CCHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SKLGVSITKITRGAANLQDNNIKDFLRKKISY
HHHCCHHHHHHHHHCCCCCCCHHHHHHHHHCC
>Mature Secondary Structure 
SREQAFEMLIKILCKTDSTDDMKLILECILTRSEMEDLIDRIRIYNELLNTSNSQREVA
CHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
SKLGVSITKITRGAANLQDNNIKDFLRKKISY
HHHCCHHHHHHHHHCCCCCCCHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA