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The map label for this gene is lipA [H]

Identifier: 182681023

GI number: 182681023

Start: 555536

End: 556669

Strand: Direct

Name: lipA [H]

Synonym: XfasM23_0462

Alternate gene names: 182681023

Gene position: 555536-556669 (Clockwise)

Preceding gene: 182681022

Following gene: 182681024

Centisome position: 21.91

GC content: 42.86

Gene sequence:

>1134_bases
GTGAGAATCATCTCCTTAGCATTTTCTGATCTAAATTTTTCGGGGTGGGTTGAATTGATTAATTTTATTTATTATGAGTT
AATGAAGAAAATGCTTGCGTGCGTGATGAGCACAGTTTTTTTCGTTAATACGATTGCTTTAGTAATGCTGACGGGTATGG
GGGTTGCGTCGGCTGCATCCAAAGACAGTTATGCGGCGACAAAATATCCGATCATTTTCGAACCTGGTTTCGGGGGAGTC
GATAAGCTATTTGTTTTTATTGATTATTTTTACAGGATTCCCGAGGATTTGCGAGCACATGGTGCAAATGTCTATCTGTC
CACTTCATCTGCTTTTCAGAGACCAGATGGCCCAAATGGTCGTGGTGAGCAATTACTCGCATACGTTAAGGCAGTCCTTG
CTATTACCGGGGCGGAGAAAGTTAATTTGATTGGCTATAGTCAGGGTGGATTGACTGTCCGTTACGTAGCGGCTGTTGCT
CCCGATCTTGTTGCTTCGTTGACGACTATTGGTACGCCTCATCATGGTTCGGAATTGGCAGATTACTTTGAGGAGCTGTT
GAATAAGAATCCAATTAGGCCGTTGTCAACGGCGCTGGGTGGCCTCAGTAATGCGTTTGCTTCGATAACAACCGCTAATC
TGAATCAGGATATGTTTGCTGCGTTAAAGAGTCTAACGACATCGCAAGTAGTGATATTTAACGAGAATTATCCAAGTGCT
GGCCTTGATAAACTTGCTTCATGTAAGGGAGGAGCAGAATTTGAAACCTTCGGAAGTCATCGTCAATACCTATACTCATG
GGGTGGTGCAGCGATTAAGGAAAAAGAATCACTCTTCGGTACCAATGTTATCGATACAAGTGTGATTCCTTTTATTGATC
TTGCAAATTTTGTCGATCCAACTACAAAAGCGTTGTATCGATTTGGGAGAGTGATGATCAATCGCGGCTCTGGTAGCAAT
GATGGCATGGTCTCTACCTGTAGCTCCATGTTCGGTAAGGTAATAAGCAATAACTTTAATTGGAACCATTTTGATGAAAT
AAACCAAGTTCTTGGTATCCGCGGTGCGTATGCGGAGGATCCTTTAGCAGTAATACGCACTCATGTGAATCGTCTGAAAA
TGCAGGGTCTTTGA

Upstream 100 bases:

>100_bases
TTTGAGGTTGCGAAATAGAGAAATAGCTTTCTAAGTCTTAATGATAGTAATTGCTTATTTTTTTATTATTTAATTCTATT
TGAAATGGATTTTCTAAGGT

Downstream 100 bases:

>100_bases
GTGATAAAAAAATATTCGTTTGTGAATCATCGTATTGTGCTTTATTTGATATTGGGCTGCGTGGTCGTATGTGGTGTTTG
GTATTCGTTCGATGTACGGC

Product: alpha/beta hydrolase fold protein

Products: NA

Alternate protein names: Triacylglycerol lipase [H]

Number of amino acids: Translated: 377; Mature: 377

Protein sequence:

>377_residues
MRIISLAFSDLNFSGWVELINFIYYELMKKMLACVMSTVFFVNTIALVMLTGMGVASAASKDSYAATKYPIIFEPGFGGV
DKLFVFIDYFYRIPEDLRAHGANVYLSTSSAFQRPDGPNGRGEQLLAYVKAVLAITGAEKVNLIGYSQGGLTVRYVAAVA
PDLVASLTTIGTPHHGSELADYFEELLNKNPIRPLSTALGGLSNAFASITTANLNQDMFAALKSLTTSQVVIFNENYPSA
GLDKLASCKGGAEFETFGSHRQYLYSWGGAAIKEKESLFGTNVIDTSVIPFIDLANFVDPTTKALYRFGRVMINRGSGSN
DGMVSTCSSMFGKVISNNFNWNHFDEINQVLGIRGAYAEDPLAVIRTHVNRLKMQGL

Sequences:

>Translated_377_residues
MRIISLAFSDLNFSGWVELINFIYYELMKKMLACVMSTVFFVNTIALVMLTGMGVASAASKDSYAATKYPIIFEPGFGGV
DKLFVFIDYFYRIPEDLRAHGANVYLSTSSAFQRPDGPNGRGEQLLAYVKAVLAITGAEKVNLIGYSQGGLTVRYVAAVA
PDLVASLTTIGTPHHGSELADYFEELLNKNPIRPLSTALGGLSNAFASITTANLNQDMFAALKSLTTSQVVIFNENYPSA
GLDKLASCKGGAEFETFGSHRQYLYSWGGAAIKEKESLFGTNVIDTSVIPFIDLANFVDPTTKALYRFGRVMINRGSGSN
DGMVSTCSSMFGKVISNNFNWNHFDEINQVLGIRGAYAEDPLAVIRTHVNRLKMQGL
>Mature_377_residues
MRIISLAFSDLNFSGWVELINFIYYELMKKMLACVMSTVFFVNTIALVMLTGMGVASAASKDSYAATKYPIIFEPGFGGV
DKLFVFIDYFYRIPEDLRAHGANVYLSTSSAFQRPDGPNGRGEQLLAYVKAVLAITGAEKVNLIGYSQGGLTVRYVAAVA
PDLVASLTTIGTPHHGSELADYFEELLNKNPIRPLSTALGGLSNAFASITTANLNQDMFAALKSLTTSQVVIFNENYPSA
GLDKLASCKGGAEFETFGSHRQYLYSWGGAAIKEKESLFGTNVIDTSVIPFIDLANFVDPTTKALYRFGRVMINRGSGSN
DGMVSTCSSMFGKVISNNFNWNHFDEINQVLGIRGAYAEDPLAVIRTHVNRLKMQGL

Specific function: Catalyzes the hydrolysis of triglycerides [H]

COG id: COG1075

COG function: function code R; Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the AB hydrolase superfamily. Pseudomonas lipase family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000073 [H]

Pfam domain/function: PF00561 Abhydrolase_1 [H]

EC number: =3.1.1.3 [H]

Molecular weight: Translated: 41096; Mature: 41096

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: PS00120 LIPASE_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRIISLAFSDLNFSGWVELINFIYYELMKKMLACVMSTVFFVNTIALVMLTGMGVASAAS
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
KDSYAATKYPIIFEPGFGGVDKLFVFIDYFYRIPEDLRAHGANVYLSTSSAFQRPDGPNG
CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHCCCEEEEECCHHHCCCCCCCC
RGEQLLAYVKAVLAITGAEKVNLIGYSQGGLTVRYVAAVAPDLVASLTTIGTPHHGSELA
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCCCCHHHH
DYFEELLNKNPIRPLSTALGGLSNAFASITTANLNQDMFAALKSLTTSQVVIFNENYPSA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCEEEEEECCCCCH
GLDKLASCKGGAEFETFGSHRQYLYSWGGAAIKEKESLFGTNVIDTSVIPFIDLANFVDP
HHHHHHHCCCCCCHHHHCCHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCH
TTKALYRFGRVMINRGSGSNDGMVSTCSSMFGKVISNNFNWNHFDEINQVLGIRGAYAED
HHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCC
PLAVIRTHVNRLKMQGL
HHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRIISLAFSDLNFSGWVELINFIYYELMKKMLACVMSTVFFVNTIALVMLTGMGVASAAS
CEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHCC
KDSYAATKYPIIFEPGFGGVDKLFVFIDYFYRIPEDLRAHGANVYLSTSSAFQRPDGPNG
CCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHCCHHHHHCCCEEEEECCHHHCCCCCCCC
RGEQLLAYVKAVLAITGAEKVNLIGYSQGGLTVRYVAAVAPDLVASLTTIGTPHHGSELA
HHHHHHHHHHHHHHHCCCCEEEEEEECCCCCEEEHHHHHHHHHHHHHHHCCCCCCCHHHH
DYFEELLNKNPIRPLSTALGGLSNAFASITTANLNQDMFAALKSLTTSQVVIFNENYPSA
HHHHHHHCCCCCCHHHHHHHHHHHHHHHHEECCCCHHHHHHHHHCCCCEEEEEECCCCCH
GLDKLASCKGGAEFETFGSHRQYLYSWGGAAIKEKESLFGTNVIDTSVIPFIDLANFVDP
HHHHHHHCCCCCCHHHHCCHHHHHHHCCCCHHHHHHHHCCCCCHHHHHHHHHHHHHHCCH
TTKALYRFGRVMINRGSGSNDGMVSTCSSMFGKVISNNFNWNHFDEINQVLGIRGAYAED
HHHHHHHHHHHEEECCCCCCCCHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHCCCCCCCC
PLAVIRTHVNRLKMQGL
HHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1987151; 9032073; 9032074 [H]