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The map label for this gene is atpB [H]

Identifier: 182680991

GI number: 182680991

Start: 534004

End: 534801

Strand: Reverse

Name: atpB [H]

Synonym: XfasM23_0430

Alternate gene names: 182680991

Gene position: 534801-534004 (Counterclockwise)

Preceding gene: 182680992

Following gene: 182680990

Centisome position: 21.09

GC content: 46.24

Gene sequence:

>798_bases
ATGGCAGGCGAGGAAGCAACTCCCACCTCATACATTCAACACCACCTGCACAATCTGACTTTTCAAATGCAGGACGGCAG
CAAATTTTGGGTACTGCATCTTGACACGCTGATAATGGCTGTCTTGATGGGGTTGGTAATGGTATTGGCATTTTGGAGCG
GCACATGCAAGGCCACTTCAGGGATACCTGGGAAATGGCAAGCATTCGTCGAGGTTTGCTTGGAATTTGTCGACCGCCAA
GTCAAAGATACCTACCACGGTCCGAGTAAGTTGGTCACACCAATCGCAATAACTCTGTTCTTTTGGATATTTTTGATGAA
CCTCATAAAGGTGATCCCTGCTGACTTCATCGCTATCCCATTTAGCTGGGCAGGTGTACATGCTTGGAAACCAGTTCCAA
CGGCTGACGTCAATGCAACGCTTGGGATGTCAATCAGTGTCTTTTTCTTGATGCTCTTCTTCTCATTTCGTGCAAAGGGT
ATAAGCGGCTTCATCAAAGAATTTATTACAACACCTTTCGGCAAATGGATGATGCCGTTCAACATTGTCCTCAACATTGT
AGAATGGCTAAGTAAACCGATTTCACTAGCGATGCGGCTCTTCGGAAACATGTTTGGTGGCGAGATCGTTTTCTTATTGA
TTTGGGTACTTGGTGGTGCAGGCATTTCGGGCATGCTTGCCAGCAGTACGTTTGGCCTAGCCTGGATGCTGTTTCACTTA
CTGGTGATTCCACTCCAAGCATTTATTTTCATGATGCTCTCGATCGTATACCTGAGCCTGTCAGAAGACTCTCATTGA

Upstream 100 bases:

>100_bases
TAGGGCTTCTAAGTGGCATTACAATTGGCTTGTTTTTTCAAGCCTTAACTATGACCAGACAACAATCATAAAGATTTTTC
AGACTTAAGGTCCCAGACAC

Downstream 100 bases:

>100_bases
GTTGTTCCCCATCATCTTAAGTTTGCTTCCTCACCCTCAATTATTTCATTACCGGAGAAAATCATGTCCCTAGATGTCCT
GACCAATTTCGCTCAAATCC

Product: F0F1 ATP synthase subunit A

Products: ADP; phosphate; H+

Alternate protein names: ATP synthase F0 sector subunit a; F-ATPase subunit 6 [H]

Number of amino acids: Translated: 265; Mature: 264

Protein sequence:

>265_residues
MAGEEATPTSYIQHHLHNLTFQMQDGSKFWVLHLDTLIMAVLMGLVMVLAFWSGTCKATSGIPGKWQAFVEVCLEFVDRQ
VKDTYHGPSKLVTPIAITLFFWIFLMNLIKVIPADFIAIPFSWAGVHAWKPVPTADVNATLGMSISVFFLMLFFSFRAKG
ISGFIKEFITTPFGKWMMPFNIVLNIVEWLSKPISLAMRLFGNMFGGEIVFLLIWVLGGAGISGMLASSTFGLAWMLFHL
LVIPLQAFIFMMLSIVYLSLSEDSH

Sequences:

>Translated_265_residues
MAGEEATPTSYIQHHLHNLTFQMQDGSKFWVLHLDTLIMAVLMGLVMVLAFWSGTCKATSGIPGKWQAFVEVCLEFVDRQ
VKDTYHGPSKLVTPIAITLFFWIFLMNLIKVIPADFIAIPFSWAGVHAWKPVPTADVNATLGMSISVFFLMLFFSFRAKG
ISGFIKEFITTPFGKWMMPFNIVLNIVEWLSKPISLAMRLFGNMFGGEIVFLLIWVLGGAGISGMLASSTFGLAWMLFHL
LVIPLQAFIFMMLSIVYLSLSEDSH
>Mature_264_residues
AGEEATPTSYIQHHLHNLTFQMQDGSKFWVLHLDTLIMAVLMGLVMVLAFWSGTCKATSGIPGKWQAFVEVCLEFVDRQV
KDTYHGPSKLVTPIAITLFFWIFLMNLIKVIPADFIAIPFSWAGVHAWKPVPTADVNATLGMSISVFFLMLFFSFRAKGI
SGFIKEFITTPFGKWMMPFNIVLNIVEWLSKPISLAMRLFGNMFGGEIVFLLIWVLGGAGISGMLASSTFGLAWMLFHLL
VIPLQAFIFMMLSIVYLSLSEDSH

Specific function: Key component of the proton channel; it plays a direct role in the translocation of protons across the membrane [H]

COG id: COG0356

COG function: function code C; F0F1-type ATP synthase, subunit a

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase A chain family [H]

Homologues:

Organism=Escherichia coli, GI1790176, Length=276, Percent_Identity=45.6521739130435, Blast_Score=227, Evalue=7e-61,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000568
- InterPro:   IPR023011 [H]

Pfam domain/function: PF00119 ATP-synt_A [H]

EC number: 3.6.3.14

Molecular weight: Translated: 29703; Mature: 29572

Theoretical pI: Translated: 7.27; Mature: 7.27

Prosite motif: PS00449 ATPASE_A

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.8 %Cys     (Translated Protein)
6.0 %Met     (Translated Protein)
6.8 %Cys+Met (Translated Protein)
0.8 %Cys     (Mature Protein)
5.7 %Met     (Mature Protein)
6.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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HHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
AGEEATPTSYIQHHLHNLTFQMQDGSKFWVLHLDTLIMAVLMGLVMVLAFWSGTCKATS
CCCCCCCHHHHHHHHHHCEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
GIPGKWQAFVEVCLEFVDRQVKDTYHGPSKLVTPIAITLFFWIFLMNLIKVIPADFIAIP
CCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHCHHHHEEC
FSWAGVHAWKPVPTADVNATLGMSISVFFLMLFFSFRAKGISGFIKEFITTPFGKWMMPF
CCCCCCCCCCCCCCCCCCCHHCHHHHHHHHHHHHHHHHCCHHHHHHHHHHCCCHHHHHHH
NIVLNIVEWLSKPISLAMRLFGNMFGGEIVFLLIWVLGGAGISGMLASSTFGLAWMLFHL
HHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
LVIPLQAFIFMMLSIVYLSLSEDSH
HHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: Borate; diphosphate; HCO3- [C]

Metal ions: Co2+; Fe2+; Mn2+; Zn2+ [C]

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; H2O; H+

Specific reaction: ATP + H2O + H+(in) = ADP + phosphate + H+(out)

General reaction: Phosphorous acid anhydride hydrolysis [C]

Inhibitor: Ca2+; CN-; Efrapeptin; Ethidiumbromide; Guanidines analogs; Oligomycin; Quercetin; Trialkyl tin derivatives; Venturicidin [C]

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12700255 [H]