Click here to switch to the map view.

The map label for this gene is atpA [H]

Identifier: 182680987

GI number: 182680987

Start: 530917

End: 532464

Strand: Reverse

Name: atpA [H]

Synonym: XfasM23_0426

Alternate gene names: 182680987

Gene position: 532464-530917 (Counterclockwise)

Preceding gene: 182680988

Following gene: 182680986

Centisome position: 21.0

GC content: 50.39

Gene sequence:

>1548_bases
ATGGCAACCACCCTCAACCCTTCCGAAATAAGCGAATTGATTAAGACTCGCATCGAACAGGTCAAACTATCCGCAGAATC
CCGTAACGAAGGCACCGTGACCAGCGTTTCCGATGGCATTGTGCGCATTTTTGGCTTAGCAGATGCGATGCAAGGAGAAA
TGATCGAATTGCCTAACAAAACCTATGCACTAGCACTGAATTTGGAGCGTGATTCAGTTGGTGCCGTGGTACTGGGTGAT
TACGAACATTTACGTGAAGGAGACGTCGCTAAAACAACCGGACGCATCCTTGAAGTGCCGGTTGGCAAATCCCTGTTGGG
CCGCGTTGTCAATGCTTTAGGTGAACCAATCGATGGCAAAGGTACACTAGGACCCACTCAAACTGCACCAGTGGAGCGCG
TTGCTCCTGGTGTCATCTGGCGTAAATCAGTCGATCAACCAGTACAGACCGGTTATAAGTCAGTTGATGCGATGATCCCT
ATCGGCCGCGGCCAACGCGAACTCATCATCGGAGACCGCCAAACTGGGAAAACCGCAATGGCAATCGATACAGTGATCAG
CCAGAAACACACCGGTATCAAATGCGTTTATGTAGCGATAGGCCAAAAATCTTCTACTATCGCCAATATCGTTCGAAAAC
TCGAAGAGAATGATGCGCTGGACCACACTATCGTCGTAGCCGCAACCGCATCTGAATCAGCCGCACTTCAGTACATCAGT
GCCTACGCTGGCTGCACCATGGGCGAATACTTCATGGACCGTGGCGAGGACGCACTCATCATCTATGACGATTTGTCGAA
ACAAGCCGTTGCCTATCGCCAAATCTCGCTACTCTTAAAACGTCCCCCTGGTCGAGAAGCTTACCCGGGCGACGTATTCT
ACCTGCACTCGCGTCTGCTGGAGCGTGCCGCTCGTGTGTCTGAAGAATATGTCGAAAAATTCACCCAAGGTGAGGTGAAA
GGAAAAACAGGATCCTTAACTGCATTACCAATCATCGAAACACAAGCTGGCGACGTGTCCGCCTTTGTACCAACCAACGT
AATTTCAATTACTGATGGCCAGATCTTCCTGGAAACTGATCTTTTCAATGCTGGTATACGTCCAGCTGTCAACGCCGGCA
TCTCCGTATCGCGCGTCGGTGGCTCGGCACAGACTAAAATTATCAAGAAACTGTCAGGGGGCATCCGCATCTCACTGGCA
CAATACCGTGAGCTGGCAGCATTCGCGCAGTTTGCATCTGACCTAGATGAAACAACCCGCAAGCAACTCGAGCGCGGCCA
ACGTGTCACTGAACTGATGAAGCAGAAACAGTACACCTCAATGTCCGTCGCCAACCAAGCGTTATCAATCTACGCAGTCA
GCGAAGGCTACCTTGACGACATACCAGTGCACAAAGTACTCACCTTCGAAGAAGGCCTACACGCCCATTTTTCCAACACT
CAAGGCGCGCTAATCGACAAGATCAATAACTCCGGCGACTGGGACAACAACATTGAAGCTGCTTTCAAGCAGCACATTGA
AGAATTTAAGACCACGGGCAGCTGGTAA

Upstream 100 bases:

>100_bases
GGCTCTATCAAAAGCAAGCTCACACGCTTACAGGCCTCGCTGACCCACTGAAACTCACAAACTGTCAGCTCCCCCAGGCC
GACGCAATTAGGACTCAACG

Downstream 100 bases:

>100_bases
CAGTAGCGGCTGCGGGCGGGCCTCAGGCTAGCTACTGTAAAGGCTTGAATGGGCTTCATCTCACCCCCCCTATGAATCAA
ACGAGTAAGCAATGGCAAGC

Product: F0F1 ATP synthase subunit alpha

Products: NA

Alternate protein names: ATP synthase F1 sector subunit alpha; F-ATPase subunit alpha [H]

Number of amino acids: Translated: 515; Mature: 514

Protein sequence:

>515_residues
MATTLNPSEISELIKTRIEQVKLSAESRNEGTVTSVSDGIVRIFGLADAMQGEMIELPNKTYALALNLERDSVGAVVLGD
YEHLREGDVAKTTGRILEVPVGKSLLGRVVNALGEPIDGKGTLGPTQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIP
IGRGQRELIIGDRQTGKTAMAIDTVISQKHTGIKCVYVAIGQKSSTIANIVRKLEENDALDHTIVVAATASESAALQYIS
AYAGCTMGEYFMDRGEDALIIYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTQGEVK
GKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGSAQTKIIKKLSGGIRISLA
QYRELAAFAQFASDLDETTRKQLERGQRVTELMKQKQYTSMSVANQALSIYAVSEGYLDDIPVHKVLTFEEGLHAHFSNT
QGALIDKINNSGDWDNNIEAAFKQHIEEFKTTGSW

Sequences:

>Translated_515_residues
MATTLNPSEISELIKTRIEQVKLSAESRNEGTVTSVSDGIVRIFGLADAMQGEMIELPNKTYALALNLERDSVGAVVLGD
YEHLREGDVAKTTGRILEVPVGKSLLGRVVNALGEPIDGKGTLGPTQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIP
IGRGQRELIIGDRQTGKTAMAIDTVISQKHTGIKCVYVAIGQKSSTIANIVRKLEENDALDHTIVVAATASESAALQYIS
AYAGCTMGEYFMDRGEDALIIYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTQGEVK
GKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGSAQTKIIKKLSGGIRISLA
QYRELAAFAQFASDLDETTRKQLERGQRVTELMKQKQYTSMSVANQALSIYAVSEGYLDDIPVHKVLTFEEGLHAHFSNT
QGALIDKINNSGDWDNNIEAAFKQHIEEFKTTGSW
>Mature_514_residues
ATTLNPSEISELIKTRIEQVKLSAESRNEGTVTSVSDGIVRIFGLADAMQGEMIELPNKTYALALNLERDSVGAVVLGDY
EHLREGDVAKTTGRILEVPVGKSLLGRVVNALGEPIDGKGTLGPTQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIPI
GRGQRELIIGDRQTGKTAMAIDTVISQKHTGIKCVYVAIGQKSSTIANIVRKLEENDALDHTIVVAATASESAALQYISA
YAGCTMGEYFMDRGEDALIIYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLLERAARVSEEYVEKFTQGEVKG
KTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETDLFNAGIRPAVNAGISVSRVGGSAQTKIIKKLSGGIRISLAQ
YRELAAFAQFASDLDETTRKQLERGQRVTELMKQKQYTSMSVANQALSIYAVSEGYLDDIPVHKVLTFEEGLHAHFSNTQ
GALIDKINNSGDWDNNIEAAFKQHIEEFKTTGSW

Specific function: Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit [H]

COG id: COG0056

COG function: function code C; F0F1-type ATP synthase, alpha subunit

Gene ontology:

Cell location: Cell inner membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ATPase alpha/beta chains family [H]

Homologues:

Organism=Homo sapiens, GI50345984, Length=510, Percent_Identity=54.3137254901961, Blast_Score=556, Evalue=1e-158,
Organism=Homo sapiens, GI4757810, Length=510, Percent_Identity=54.3137254901961, Blast_Score=556, Evalue=1e-158,
Organism=Homo sapiens, GI19913428, Length=317, Percent_Identity=28.391167192429, Blast_Score=110, Evalue=3e-24,
Organism=Homo sapiens, GI19913426, Length=384, Percent_Identity=27.34375, Blast_Score=104, Evalue=2e-22,
Organism=Homo sapiens, GI32189394, Length=389, Percent_Identity=24.6786632390745, Blast_Score=99, Evalue=1e-20,
Organism=Homo sapiens, GI19913424, Length=336, Percent_Identity=26.7857142857143, Blast_Score=80, Evalue=4e-15,
Organism=Escherichia coli, GI1790172, Length=511, Percent_Identity=72.9941291585127, Blast_Score=767, Evalue=0.0,
Organism=Escherichia coli, GI1790170, Length=431, Percent_Identity=24.5939675174014, Blast_Score=125, Evalue=6e-30,
Organism=Escherichia coli, GI1788251, Length=364, Percent_Identity=25.5494505494505, Blast_Score=112, Evalue=6e-26,
Organism=Caenorhabditis elegans, GI71988063, Length=513, Percent_Identity=53.9961013645224, Blast_Score=556, Evalue=1e-159,
Organism=Caenorhabditis elegans, GI71988080, Length=513, Percent_Identity=53.9961013645224, Blast_Score=555, Evalue=1e-158,
Organism=Caenorhabditis elegans, GI71988074, Length=513, Percent_Identity=50.0974658869396, Blast_Score=499, Evalue=1e-141,
Organism=Caenorhabditis elegans, GI17570191, Length=318, Percent_Identity=26.4150943396226, Blast_Score=107, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17510931, Length=373, Percent_Identity=25.7372654155496, Blast_Score=106, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI25144756, Length=331, Percent_Identity=23.8670694864048, Blast_Score=92, Evalue=9e-19,
Organism=Caenorhabditis elegans, GI17565854, Length=265, Percent_Identity=27.9245283018868, Blast_Score=75, Evalue=6e-14,
Organism=Caenorhabditis elegans, GI17509265, Length=50, Percent_Identity=58, Blast_Score=72, Evalue=8e-13,
Organism=Saccharomyces cerevisiae, GI6319370, Length=519, Percent_Identity=51.8304431599229, Blast_Score=546, Evalue=1e-156,
Organism=Saccharomyces cerevisiae, GI6319603, Length=326, Percent_Identity=29.4478527607362, Blast_Score=112, Evalue=1e-25,
Organism=Saccharomyces cerevisiae, GI6322581, Length=426, Percent_Identity=24.4131455399061, Blast_Score=107, Evalue=5e-24,
Organism=Drosophila melanogaster, GI24658560, Length=520, Percent_Identity=53.8461538461538, Blast_Score=559, Evalue=1e-159,
Organism=Drosophila melanogaster, GI281361666, Length=321, Percent_Identity=27.7258566978193, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24646341, Length=321, Percent_Identity=27.7258566978193, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI17136796, Length=321, Percent_Identity=27.7258566978193, Blast_Score=114, Evalue=2e-25,
Organism=Drosophila melanogaster, GI24638766, Length=393, Percent_Identity=23.6641221374046, Blast_Score=99, Evalue=7e-21,
Organism=Drosophila melanogaster, GI28574560, Length=341, Percent_Identity=24.633431085044, Blast_Score=89, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24583988, Length=266, Percent_Identity=27.8195488721804, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583986, Length=266, Percent_Identity=27.8195488721804, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583984, Length=266, Percent_Identity=27.8195488721804, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24583992, Length=266, Percent_Identity=27.8195488721804, Blast_Score=78, Evalue=2e-14,
Organism=Drosophila melanogaster, GI20129479, Length=336, Percent_Identity=26.7857142857143, Blast_Score=72, Evalue=8e-13,

Paralogues:

None

Copy number: 9,000 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020003
- InterPro:   IPR000194
- InterPro:   IPR005294
- InterPro:   IPR017458
- InterPro:   IPR018118
- InterPro:   IPR000793
- InterPro:   IPR004100 [H]

Pfam domain/function: PF00006 ATP-synt_ab; PF00306 ATP-synt_ab_C; PF02874 ATP-synt_ab_N [H]

EC number: =3.6.3.14 [H]

Molecular weight: Translated: 55984; Mature: 55853

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: PS00152 ATPASE_ALPHA_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MATTLNPSEISELIKTRIEQVKLSAESRNEGTVTSVSDGIVRIFGLADAMQGEMIELPNK
CCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEHHHHHHHCCCEEECCCC
TYALALNLERDSVGAVVLGDYEHLREGDVAKTTGRILEVPVGKSLLGRVVNALGEPIDGK
EEEEEEEECCCCCCEEEECCHHHHCCCCCHHCCCCEEEECCCHHHHHHHHHHHCCCCCCC
GTLGPTQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTAM
CCCCCCCCCCHHHHCCCHHHHHCCCCHHHHHHHHHHHEEECCCCCEEEEEECCCCCCHHH
AIDTVISQKHTGIKCVYVAIGQKSSTIANIVRKLEENDALDHTIVVAATASESAALQYIS
HHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHH
AYAGCTMGEYFMDRGEDALIIYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLL
HHHCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ERAARVSEEYVEKFTQGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETD
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEC
LFNAGIRPAVNAGISVSRVGGSAQTKIIKKLSGGIRISLAQYRELAAFAQFASDLDETTR
CCCCCCCHHHHCCEEEEECCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
KQLERGQRVTELMKQKQYTSMSVANQALSIYAVSEGYLDDIPVHKVLTFEEGLHAHFSNT
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHEEEHHCCCHHHCCCC
QGALIDKINNSGDWDNNIEAAFKQHIEEFKTTGSW
CCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
ATTLNPSEISELIKTRIEQVKLSAESRNEGTVTSVSDGIVRIFGLADAMQGEMIELPNK
CCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCEEEHHHHHHHCCCEEECCCC
TYALALNLERDSVGAVVLGDYEHLREGDVAKTTGRILEVPVGKSLLGRVVNALGEPIDGK
EEEEEEEECCCCCCEEEECCHHHHCCCCCHHCCCCEEEECCCHHHHHHHHHHHCCCCCCC
GTLGPTQTAPVERVAPGVIWRKSVDQPVQTGYKSVDAMIPIGRGQRELIIGDRQTGKTAM
CCCCCCCCCCHHHHCCCHHHHHCCCCHHHHHHHHHHHEEECCCCCEEEEEECCCCCCHHH
AIDTVISQKHTGIKCVYVAIGQKSSTIANIVRKLEENDALDHTIVVAATASESAALQYIS
HHHHHHHCCCCCEEEEEEEECCCCHHHHHHHHHHHCCCCCCEEEEEEEECCCHHHHHHHH
AYAGCTMGEYFMDRGEDALIIYDDLSKQAVAYRQISLLLKRPPGREAYPGDVFYLHSRLL
HHHCCCHHHHHHCCCCCEEEEEECCCHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHH
ERAARVSEEYVEKFTQGEVKGKTGSLTALPIIETQAGDVSAFVPTNVISITDGQIFLETD
HHHHHHHHHHHHHHHCCCCCCCCCCEEEEEEEECCCCCEEEECCCCEEEEECCEEEEEEC
LFNAGIRPAVNAGISVSRVGGSAQTKIIKKLSGGIRISLAQYRELAAFAQFASDLDETTR
CCCCCCCHHHHCCEEEEECCCCHHHHHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHH
KQLERGQRVTELMKQKQYTSMSVANQALSIYAVSEGYLDDIPVHKVLTFEEGLHAHFSNT
HHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEEECCCCCCCCCCHHEEEHHCCCHHHCCCC
QGALIDKINNSGDWDNNIEAAFKQHIEEFKTTGSW
CCHHHCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA