Click here to switch to the map view.

The map label for this gene is tldD [H]

Identifier: 182680974

GI number: 182680974

Start: 516116

End: 517573

Strand: Direct

Name: tldD [H]

Synonym: XfasM23_0412

Alternate gene names: 182680974

Gene position: 516116-517573 (Clockwise)

Preceding gene: 182680973

Following gene: 182680976

Centisome position: 20.35

GC content: 55.9

Gene sequence:

>1458_bases
ATGAAAAATACCGCACTCTCTGTCGCCGAATCCCGGCTGTTGTTGCCTGCCGGTCTGGATGACGGCCAAATTGATTCTAT
TTTCGGAACGTTACTCGGACCTGGGGTCGATTTTGGCGACCTGTATTTCCAGCACGCGCGTCGTGAGAGTTGGAGTATAG
AGGACGGTATTGTCAAGGATGGAACGCACTCGATTGAACAGGGTGTCGGGGTGCGTGCTATTTCTGGTGAGAAGACCGGT
TTTGCTTATTCCGATGACATTAACCGGGATGCGTTGCTTGAAGCGGCGTATGCCGCGCGTGCGATTTCGCGTTCACCTGG
GGATGGGGTGCAGGGGACACATGCGGTGTTGCGCCGTCATGGGCGGGAGCTGTGTTTGTATCCGGCATTGGATCCGGTGG
GTGGGATGGATAATGCTGAGAAGATTGCGGTGATGCGGCGTGTCGATCAGTTATTGCGTGTGGCTGATCCGCGTGTCACT
CAGGTGATGGTTAATTTGTCTGGTGGTGTCGATGTGGTGTTGATTGCACGCAGTGATGGTGTGCTCGCTGCGGATGTGCG
CCCGTTGGTGCGATTGAATGTGCAGGTGATCGTTGAGGGTCATGGTCGCCGTGAATCTGGTTATGCCGGTGGTGGCGGGC
GTTATGGATATGCTGAGTTGTTTGCCGATGGCCGCCCGGAGGCTTTTGCACGGGAGGCGCTTCGCCAAGCGTTGGTGAAT
CTTGAGGCGATTCCGGCTCCGGCTGGTGTGATGCCGGTGGTGCTTGGTGCTGGTTGGCCTGGTGTGTTGTTGCACGAGGC
GGTGGGCCATGGTCTTGAGGGTGATTTCAACCGTAAGGCTACCAGTGTTTATGCCGGTCGTATTGGTGAGCGCGTCGCGT
CACCAGGGGTGACGATTGTTGATGATGGGACGCTGGATGGTCGTCGTGGTTCGCTCAATATTGATGACGAAGGGACGCCT
ACGCAATGCACCACATTGATTGAAGACGGTGTGTTGGTTGGTTATATGCAGGATACGTTGAATGCTCGGTTGATGGGAGT
GGCATCGACTGGTAATGGTCGCCGTGAGTCGTTTGCACACTTGACGATGCCACGCATGACCAATACGTATATGCGTGCTG
GTGCACATAGTCGTGAGGAGATGATCCGTTCGGTTAAGAAGGGACTGTATGCGGTTAATTTCGGGGGGGGGCAGGTCGAC
ATTACCAGCGGCAAGTACGTGTTTTCGGCGACTGAAGCTTATTTGATTGAGGATGGCCGGGTGACTGCTCCGATTAAGGG
GGCTACGCTGATTGGCAATGGTCCTGAGACGATGCAGCGGGTGCGCATGATTGGGGATGATTTGGCGTTGGATGCGGGGG
TCGGGGTCTGTGGCAAAGATGGGCAGAGTGTGCCCGTCGGTGTCGGCCAACCGTCGTTACTCATTGATGGGTTGACGGTG
GGGGGGACTCAGGCATGA

Upstream 100 bases:

>100_bases
TGATGATGAAGTGGGTATGTGTGCTGCCTTCGTTTGATTTGATCTTGTTAATTCAGTGGGAGTGCTTGCGTGTTTGTTAA
TCCGCCCGCATTCTTGACTC

Downstream 100 bases:

>100_bases
ATGCGGTTAGGTTAAAAGGTGGTCGAAGGGTTTTTTCTGGTTCTGCTGATTGTTGTTATTGGAGACGCAGCGGGGAGGTG
GCTGTTTCGATTGATGTTCG

Product: peptidase U62 modulator of DNA gyrase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 485; Mature: 485

Protein sequence:

>485_residues
MKNTALSVAESRLLLPAGLDDGQIDSIFGTLLGPGVDFGDLYFQHARRESWSIEDGIVKDGTHSIEQGVGVRAISGEKTG
FAYSDDINRDALLEAAYAARAISRSPGDGVQGTHAVLRRHGRELCLYPALDPVGGMDNAEKIAVMRRVDQLLRVADPRVT
QVMVNLSGGVDVVLIARSDGVLAADVRPLVRLNVQVIVEGHGRRESGYAGGGGRYGYAELFADGRPEAFAREALRQALVN
LEAIPAPAGVMPVVLGAGWPGVLLHEAVGHGLEGDFNRKATSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTP
TQCTTLIEDGVLVGYMQDTLNARLMGVASTGNGRRESFAHLTMPRMTNTYMRAGAHSREEMIRSVKKGLYAVNFGGGQVD
ITSGKYVFSATEAYLIEDGRVTAPIKGATLIGNGPETMQRVRMIGDDLALDAGVGVCGKDGQSVPVGVGQPSLLIDGLTV
GGTQA

Sequences:

>Translated_485_residues
MKNTALSVAESRLLLPAGLDDGQIDSIFGTLLGPGVDFGDLYFQHARRESWSIEDGIVKDGTHSIEQGVGVRAISGEKTG
FAYSDDINRDALLEAAYAARAISRSPGDGVQGTHAVLRRHGRELCLYPALDPVGGMDNAEKIAVMRRVDQLLRVADPRVT
QVMVNLSGGVDVVLIARSDGVLAADVRPLVRLNVQVIVEGHGRRESGYAGGGGRYGYAELFADGRPEAFAREALRQALVN
LEAIPAPAGVMPVVLGAGWPGVLLHEAVGHGLEGDFNRKATSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTP
TQCTTLIEDGVLVGYMQDTLNARLMGVASTGNGRRESFAHLTMPRMTNTYMRAGAHSREEMIRSVKKGLYAVNFGGGQVD
ITSGKYVFSATEAYLIEDGRVTAPIKGATLIGNGPETMQRVRMIGDDLALDAGVGVCGKDGQSVPVGVGQPSLLIDGLTV
GGTQA
>Mature_485_residues
MKNTALSVAESRLLLPAGLDDGQIDSIFGTLLGPGVDFGDLYFQHARRESWSIEDGIVKDGTHSIEQGVGVRAISGEKTG
FAYSDDINRDALLEAAYAARAISRSPGDGVQGTHAVLRRHGRELCLYPALDPVGGMDNAEKIAVMRRVDQLLRVADPRVT
QVMVNLSGGVDVVLIARSDGVLAADVRPLVRLNVQVIVEGHGRRESGYAGGGGRYGYAELFADGRPEAFAREALRQALVN
LEAIPAPAGVMPVVLGAGWPGVLLHEAVGHGLEGDFNRKATSVYAGRIGERVASPGVTIVDDGTLDGRRGSLNIDDEGTP
TQCTTLIEDGVLVGYMQDTLNARLMGVASTGNGRRESFAHLTMPRMTNTYMRAGAHSREEMIRSVKKGLYAVNFGGGQVD
ITSGKYVFSATEAYLIEDGRVTAPIKGATLIGNGPETMQRVRMIGDDLALDAGVGVCGKDGQSVPVGVGQPSLLIDGLTV
GGTQA

Specific function: Suppresses the inhibitory activity of the carbon storage regulator (CsrA) [H]

COG id: COG0312

COG function: function code R; Predicted Zn-dependent proteases and their inactivated homologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase U62 family [H]

Homologues:

Organism=Escherichia coli, GI1789640, Length=484, Percent_Identity=61.3636363636364, Blast_Score=557, Evalue=1e-160,
Organism=Escherichia coli, GI1790682, Length=401, Percent_Identity=24.4389027431421, Blast_Score=69, Evalue=7e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002510 [H]

Pfam domain/function: PF01523 PmbA_TldD [H]

EC number: NA

Molecular weight: Translated: 51148; Mature: 51148

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKNTALSVAESRLLLPAGLDDGQIDSIFGTLLGPGVDFGDLYFQHARRESWSIEDGIVKD
CCCCHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCC
GTHSIEQGVGVRAISGEKTGFAYSDDINRDALLEAAYAARAISRSPGDGVQGTHAVLRRH
CCHHHHHCCCEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
GRELCLYPALDPVGGMDNAEKIAVMRRVDQLLRVADPRVTQVMVNLSGGVDVVLIARSDG
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCC
VLAADVRPLVRLNVQVIVEGHGRRESGYAGGGGRYGYAELFADGRPEAFAREALRQALVN
EEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHC
LEAIPAPAGVMPVVLGAGWPGVLLHEAVGHGLEGDFNRKATSVYAGRIGERVASPGVTIV
CCCCCCCCCCHHHEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
DDGTLDGRRGSLNIDDEGTPTQCTTLIEDGVLVGYMQDTLNARLMGVASTGNGRRESFAH
ECCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEEEHHHCCCEEEEEEEECCCCCHHHHHE
LTMPRMTNTYMRAGAHSREEMIRSVKKGLYAVNFGGGQVDITSGKYVFSATEAYLIEDGR
EECCHHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEEEEECCE
VTAPIKGATLIGNGPETMQRVRMIGDDLALDAGVGVCGKDGQSVPVGVGQPSLLIDGLTV
EECCCCCCEEECCCHHHHHHHHHHCCHHHHCCCCCEECCCCCCCCCCCCCCCEEEECEEC
GGTQA
CCCCC
>Mature Secondary Structure
MKNTALSVAESRLLLPAGLDDGQIDSIFGTLLGPGVDFGDLYFQHARRESWSIEDGIVKD
CCCCHHHHHHCCEEEECCCCCCCHHHHHHHHHCCCCCHHHHHHHHHHCCCCCCCCCCCCC
GTHSIEQGVGVRAISGEKTGFAYSDDINRDALLEAAYAARAISRSPGDGVQGTHAVLRRH
CCHHHHHCCCEEEECCCCCCCEECCCCCHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHC
GRELCLYPALDPVGGMDNAEKIAVMRRVDQLLRVADPRVTQVMVNLSGGVDVVLIARSDG
CCEEEEEECCCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCEEEEEECCCC
VLAADVRPLVRLNVQVIVEGHGRRESGYAGGGGRYGYAELFADGRPEAFAREALRQALVN
EEEECCCCEEEEEEEEEEECCCCCCCCCCCCCCCCCHHHHHCCCCCHHHHHHHHHHHHHC
LEAIPAPAGVMPVVLGAGWPGVLLHEAVGHGLEGDFNRKATSVYAGRIGERVASPGVTIV
CCCCCCCCCCHHHEECCCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCCEEE
DDGTLDGRRGSLNIDDEGTPTQCTTLIEDGVLVGYMQDTLNARLMGVASTGNGRRESFAH
ECCCCCCCCCCCCCCCCCCCHHHHHHHHCCEEEEEHHHCCCEEEEEEEECCCCCHHHHHE
LTMPRMTNTYMRAGAHSREEMIRSVKKGLYAVNFGGGQVDITSGKYVFSATEAYLIEDGR
EECCHHHHHHHHCCCCCHHHHHHHHHCCEEEEEECCCEEEEECCCEEEEECEEEEEECCE
VTAPIKGATLIGNGPETMQRVRMIGDDLALDAGVGVCGKDGQSVPVGVGQPSLLIDGLTV
EECCCCCCEEECCCHHHHHHHHHHCCHHHHCCCCCEECCCCCCCCCCCCCCCEEEECEEC
GGTQA
CCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]