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The map label for this gene is pncB [H]

Identifier: 182680947

GI number: 182680947

Start: 476441

End: 477625

Strand: Direct

Name: pncB [H]

Synonym: XfasM23_0385

Alternate gene names: 182680947

Gene position: 476441-477625 (Clockwise)

Preceding gene: 182680944

Following gene: 182680949

Centisome position: 18.79

GC content: 50.21

Gene sequence:

>1185_bases
ATGGAATTTATTATAAAGTCGCTCCTCGACACTGATTTATATAAATTCACGATGATGCAGGCGGTGTTGCATCAATACCC
TGGGGCACAGGTGGAGTACAGGTTTAAATGCCGTACGCCTGGTGTGGATCTGGCGCGTTTCATCAACGAAATCTCTCATG
AGATTGATGGGCTATGTGGGCTGTGTTTTTCTAAGGAGGAACTGGATTATTTGCGCGGCTTGCGCTTCATGAAGCCAGAT
TTCGTTGATTTCCTTGGACTGTTTCATTTAGACCGTAAATACCTGCAATTGCGTGCCTCGTCCCAGGTGCCGGGCGAGAT
TGAATTGGATATTCGTGGCCCATGGTTACATACGATTCTGTTCGAGGTGCCGTTGTTGGCGATTATCAATGAGGTTTGGT
TCCGCAATACAAGCGTGTTGAATCTTGATGTGGGTCGTGACCGATTGGATGCCAAGGTACGTTTACTTAAAGACGAGAGT
GGTTATGAGGAGTGCAGCATTGCTGACTATGGCACCCGCCGCCGTTACTCGCGGCAGTGGCATGCCGAATTATTGCCGTT
GTTGGCGCAAGGTTTAGGGTCGAACTTCGTTGGTACCAGTAACGTTTATTTCGCCAAGCAGTATGGCTATACCCCATTGG
GGACGATGGCACACGAGTATCTACAGGCATTTCAGGCATTGGGACCGCGCCTGCGTGATTCCCAGGTGGCAGGGTTGGAA
GCCTGGGCGCGTGAGTACCGCGGCGATTTAGGAATTGCGTTGTCGGATGTTGTTGGGTTGGATGCGTTTTTGGGTGACTT
TGACTTGTATTTTTGCAAGTTGTTTGACGGAATGCGCCACGACTCCGGAGATCCATTTAAATGGGGGGAGCGCATCATTA
TGCATCTGGAGTCGCATCGTATCGATCCACGTACCAAGGTGCTGGTATTCAGTGATGGACTTGATATGAATAAGGTCATG
CGGTTGTACCAGCACTTCCGTGGCCGTTGTCGCTTGGCGTTTGGCGTAGGGACGAGTTTGACGAATGATCTCGGGCCGAC
GCCATTGCAGATCGTGATTAAAATGGTCCGTTGCAATGGTCAGCCAGTGGCGAAGCTCAGTGATTCTCCGGGTAAAAGCA
TGTGCGATGATCCAGGGTACCTGCATTACTTGCGTCAGGTGTTTGGGGTATCTGCCGATGTTTGA

Upstream 100 bases:

>100_bases
GCGTGCCATTGATTGGAGTGGATGTGAAGTTACATGCAGAGTATCCTGCAACGCTTGCCTGGGGGCGCTGAGATTCGGTG
AATGTTGTGATGAGTAATAT

Downstream 100 bases:

>100_bases
TTTTTATAGCGGCCGCTGCTTGTGGTTTTAGATCGGATACTGCACTCAATGCTTGATTGACGATCATTGTTTTTTGGCTA
CGCCGTTGTTGTGGCTGAGT

Product: nicotinate phosphoribosyltransferase

Products: NA

Alternate protein names: NAPRTase [H]

Number of amino acids: Translated: 394; Mature: 394

Protein sequence:

>394_residues
MEFIIKSLLDTDLYKFTMMQAVLHQYPGAQVEYRFKCRTPGVDLARFINEISHEIDGLCGLCFSKEELDYLRGLRFMKPD
FVDFLGLFHLDRKYLQLRASSQVPGEIELDIRGPWLHTILFEVPLLAIINEVWFRNTSVLNLDVGRDRLDAKVRLLKDES
GYEECSIADYGTRRRYSRQWHAELLPLLAQGLGSNFVGTSNVYFAKQYGYTPLGTMAHEYLQAFQALGPRLRDSQVAGLE
AWAREYRGDLGIALSDVVGLDAFLGDFDLYFCKLFDGMRHDSGDPFKWGERIIMHLESHRIDPRTKVLVFSDGLDMNKVM
RLYQHFRGRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDPGYLHYLRQVFGVSADV

Sequences:

>Translated_394_residues
MEFIIKSLLDTDLYKFTMMQAVLHQYPGAQVEYRFKCRTPGVDLARFINEISHEIDGLCGLCFSKEELDYLRGLRFMKPD
FVDFLGLFHLDRKYLQLRASSQVPGEIELDIRGPWLHTILFEVPLLAIINEVWFRNTSVLNLDVGRDRLDAKVRLLKDES
GYEECSIADYGTRRRYSRQWHAELLPLLAQGLGSNFVGTSNVYFAKQYGYTPLGTMAHEYLQAFQALGPRLRDSQVAGLE
AWAREYRGDLGIALSDVVGLDAFLGDFDLYFCKLFDGMRHDSGDPFKWGERIIMHLESHRIDPRTKVLVFSDGLDMNKVM
RLYQHFRGRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDPGYLHYLRQVFGVSADV
>Mature_394_residues
MEFIIKSLLDTDLYKFTMMQAVLHQYPGAQVEYRFKCRTPGVDLARFINEISHEIDGLCGLCFSKEELDYLRGLRFMKPD
FVDFLGLFHLDRKYLQLRASSQVPGEIELDIRGPWLHTILFEVPLLAIINEVWFRNTSVLNLDVGRDRLDAKVRLLKDES
GYEECSIADYGTRRRYSRQWHAELLPLLAQGLGSNFVGTSNVYFAKQYGYTPLGTMAHEYLQAFQALGPRLRDSQVAGLE
AWAREYRGDLGIALSDVVGLDAFLGDFDLYFCKLFDGMRHDSGDPFKWGERIIMHLESHRIDPRTKVLVFSDGLDMNKVM
RLYQHFRGRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNGQPVAKLSDSPGKSMCDDPGYLHYLRQVFGVSADV

Specific function: NAD biosynthesis; nicotinamide to NaMN; second step. [C]

COG id: COG1488

COG function: function code H; Nicotinic acid phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the NAPRTase family [H]

Homologues:

Organism=Escherichia coli, GI1787162, Length=391, Percent_Identity=42.9667519181586, Blast_Score=308, Evalue=5e-85,
Organism=Saccharomyces cerevisiae, GI6324783, Length=418, Percent_Identity=28.4688995215311, Blast_Score=186, Evalue=5e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006406
- InterPro:   IPR015977
- InterPro:   IPR007229
- InterPro:   IPR002638 [H]

Pfam domain/function: PF04095 NAPRTase [H]

EC number: =2.4.2.11 [H]

Molecular weight: Translated: 45007; Mature: 45007

Theoretical pI: Translated: 6.73; Mature: 6.73

Prosite motif: PS00213 LIPOCALIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEFIIKSLLDTDLYKFTMMQAVLHQYPGAQVEYRFKCRTPGVDLARFINEISHEIDGLCG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LCFSKEELDYLRGLRFMKPDFVDFLGLFHLDRKYLQLRASSQVPGEIELDIRGPWLHTIL
HHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHH
FEVPLLAIINEVWFRNTSVLNLDVGRDRLDAKVRLLKDESGYEECSIADYGTRRRYSRQW
HHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHH
HAELLPLLAQGLGSNFVGTSNVYFAKQYGYTPLGTMAHEYLQAFQALGPRLRDSQVAGLE
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AWAREYRGDLGIALSDVVGLDAFLGDFDLYFCKLFDGMRHDSGDPFKWGERIIMHLESHR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
IDPRTKVLVFSDGLDMNKVMRLYQHFRGRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNG
CCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCHHCCCCCCCHHHHHHHHHHCCC
QPVAKLSDSPGKSMCDDPGYLHYLRQVFGVSADV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
>Mature Secondary Structure
MEFIIKSLLDTDLYKFTMMQAVLHQYPGAQVEYRFKCRTPGVDLARFINEISHEIDGLCG
CHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHHHHH
LCFSKEELDYLRGLRFMKPDFVDFLGLFHLDRKYLQLRASSQVPGEIELDIRGPWLHTIL
HHCCHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCCHHHHHH
FEVPLLAIINEVWFRNTSVLNLDVGRDRLDAKVRLLKDESGYEECSIADYGTRRRYSRQW
HHHHHHHHHHHHHHCCCCEEEEECCCHHHHHHHEEEECCCCCCCCCCCCCHHHHHHHHHH
HAELLPLLAQGLGSNFVGTSNVYFAKQYGYTPLGTMAHEYLQAFQALGPRLRDSQVAGLE
HHHHHHHHHHHCCCCCCCCCCEEEECCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHH
AWAREYRGDLGIALSDVVGLDAFLGDFDLYFCKLFDGMRHDSGDPFKWGERIIMHLESHR
HHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHCC
IDPRTKVLVFSDGLDMNKVMRLYQHFRGRCRLAFGVGTSLTNDLGPTPLQIVIKMVRCNG
CCCCCEEEEEECCCCHHHHHHHHHHHCCCEEEEEECCCHHCCCCCCCHHHHHHHHHHCCC
QPVAKLSDSPGKSMCDDPGYLHYLRQVFGVSADV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]