Click here to switch to the map view.

The map label for this gene is argG [H]

Identifier: 182680848

GI number: 182680848

Start: 367842

End: 369047

Strand: Direct

Name: argG [H]

Synonym: XfasM23_0285

Alternate gene names: 182680848

Gene position: 367842-369047 (Clockwise)

Preceding gene: 182680847

Following gene: 182680849

Centisome position: 14.51

GC content: 54.81

Gene sequence:

>1206_bases
ATGAGTAATAAAAACATTGTCTTGGCCTTCTCCGGTGGACTCGACACCAGCTTTTGCATCCCCTACCTGAAAGAACAGGG
CTATGCCGTACACACCGTATTTGCCGACACCGGCGGTGTTGACGAAGATGAGCGCGACTTCATTGAAAAACGTGCTGCCG
AATTAGGCGTAGCTAGCCACCTCACCGTGGATGGCGGCCCTGCCATCTGGGATGGTTTCGTAAAACAGCTTGTCTGGGCT
GGCGAAGCCTACCAAGGCCAGTACCCCTTACTTGTTTCTGATCGCTATTTAATTGTGGATGCCGTACTACAGCGTGCCGA
TGCACTGGGCACCTGCGCCGTTGCCCATGGGTGTACTGGCATGGGCAACGACCAAGTCCGCTTCGACCTGGCGATCAAAG
CACAGGGCGACTACACCATCATTGCCCCGATTCGGGAAATCCAGAAAGAGCACACCCAGACCCGTCTGTACGAACAAAAA
TACTTAGAAGAACGCGGCTTTGGCGTCCGTGCCAAACAGAAAAACTACACCATCAATGAAAACCTCCTGGGCATCACCCT
GTCTGGTGGCGAGATCGACAAATGGGAAGCCCCGGGAGAAGGTGCCCGTGGCTGGTGCGCCCCGCGCAGCGCCTGGCCCA
CCGACCCCCTCACGGTGGCTATCAAATTTGTTGAAGGCGAAGCCGTCGCCGTAGATGGAAAACCCCTTTCCGGCCCTCAG
ATTCTGATGAAACTCAACAAACTCTTCGCCTCCTATGGCGTGGGGCGCGGTATTTACACCGGCGATACCGTCATTGGCCT
AAAAGGCCGCATCGTATACGAAGCCCCTGGACTCACCGCACTGCTGACCGCCCACCGTGCCCTGGAAGACGCCGTGTTGA
CCAAACAACAGAACCGCTTCAAACCCCACATAGCCCGTAAATGGGTTGAACTGGTGTACGAAGGATTTTTCCATGACCCC
TTGAAGACCGACCTAGAGACCTTCTTAAAATCCTCCCAAGCCAACGTGAATGGTGAAATCGTCCTTGAAACCCGAGGTGG
TCGAGTCGATGCCGTCGCAGTACGCTCACCGCACATCCTCACTAGCAAAGGCGTCACCTACGCCCAAACCGCTGACTGGG
GTATTGAAGAAGCCGAAGGATTTATCAAACTCTTTGGCATGAGCTCCACCCTATACGCTCATGTAAATCGTTCCCTGCGC
TCATGA

Upstream 100 bases:

>100_bases
TGCCATCCATGAAGCTGGTAACCGCCTGCATGTACAAAAGGCCATCATGGCCGCACTTGCTTCCCAATAATTCACGCTAT
ATTTTTTTGGAACTTCCCCC

Downstream 100 bases:

>100_bases
CCGTCATTGTCTTTTCAAACCACGCCCTCCCACTGCGCCCATTGCCACACATCATGATGAAGGTTGACGCATGAGCGCGT
TGCTCGACTCCACCCTGGAT

Product: argininosuccinate synthase

Products: NA

Alternate protein names: Citrulline--aspartate ligase [H]

Number of amino acids: Translated: 401; Mature: 400

Protein sequence:

>401_residues
MSNKNIVLAFSGGLDTSFCIPYLKEQGYAVHTVFADTGGVDEDERDFIEKRAAELGVASHLTVDGGPAIWDGFVKQLVWA
GEAYQGQYPLLVSDRYLIVDAVLQRADALGTCAVAHGCTGMGNDQVRFDLAIKAQGDYTIIAPIREIQKEHTQTRLYEQK
YLEERGFGVRAKQKNYTINENLLGITLSGGEIDKWEAPGEGARGWCAPRSAWPTDPLTVAIKFVEGEAVAVDGKPLSGPQ
ILMKLNKLFASYGVGRGIYTGDTVIGLKGRIVYEAPGLTALLTAHRALEDAVLTKQQNRFKPHIARKWVELVYEGFFHDP
LKTDLETFLKSSQANVNGEIVLETRGGRVDAVAVRSPHILTSKGVTYAQTADWGIEEAEGFIKLFGMSSTLYAHVNRSLR
S

Sequences:

>Translated_401_residues
MSNKNIVLAFSGGLDTSFCIPYLKEQGYAVHTVFADTGGVDEDERDFIEKRAAELGVASHLTVDGGPAIWDGFVKQLVWA
GEAYQGQYPLLVSDRYLIVDAVLQRADALGTCAVAHGCTGMGNDQVRFDLAIKAQGDYTIIAPIREIQKEHTQTRLYEQK
YLEERGFGVRAKQKNYTINENLLGITLSGGEIDKWEAPGEGARGWCAPRSAWPTDPLTVAIKFVEGEAVAVDGKPLSGPQ
ILMKLNKLFASYGVGRGIYTGDTVIGLKGRIVYEAPGLTALLTAHRALEDAVLTKQQNRFKPHIARKWVELVYEGFFHDP
LKTDLETFLKSSQANVNGEIVLETRGGRVDAVAVRSPHILTSKGVTYAQTADWGIEEAEGFIKLFGMSSTLYAHVNRSLR
S
>Mature_400_residues
SNKNIVLAFSGGLDTSFCIPYLKEQGYAVHTVFADTGGVDEDERDFIEKRAAELGVASHLTVDGGPAIWDGFVKQLVWAG
EAYQGQYPLLVSDRYLIVDAVLQRADALGTCAVAHGCTGMGNDQVRFDLAIKAQGDYTIIAPIREIQKEHTQTRLYEQKY
LEERGFGVRAKQKNYTINENLLGITLSGGEIDKWEAPGEGARGWCAPRSAWPTDPLTVAIKFVEGEAVAVDGKPLSGPQI
LMKLNKLFASYGVGRGIYTGDTVIGLKGRIVYEAPGLTALLTAHRALEDAVLTKQQNRFKPHIARKWVELVYEGFFHDPL
KTDLETFLKSSQANVNGEIVLETRGGRVDAVAVRSPHILTSKGVTYAQTADWGIEEAEGFIKLFGMSSTLYAHVNRSLRS

Specific function: Arginine biosynthesis; seventh step. [C]

COG id: COG0137

COG function: function code E; Argininosuccinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the argininosuccinate synthase family. Type 1 subfamily [H]

Homologues:

Organism=Homo sapiens, GI53759107, Length=405, Percent_Identity=30.6172839506173, Blast_Score=136, Evalue=3e-32,
Organism=Homo sapiens, GI16950633, Length=405, Percent_Identity=30.6172839506173, Blast_Score=136, Evalue=3e-32,
Organism=Escherichia coli, GI1789563, Length=372, Percent_Identity=25.5376344086022, Blast_Score=84, Evalue=1e-17,
Organism=Saccharomyces cerevisiae, GI6324514, Length=372, Percent_Identity=29.8387096774194, Blast_Score=122, Evalue=1e-28,
Organism=Drosophila melanogaster, GI21358151, Length=369, Percent_Identity=31.7073170731707, Blast_Score=148, Evalue=8e-36,

Paralogues:

None

Copy number: 380 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001518
- InterPro:   IPR018223
- InterPro:   IPR014729 [H]

Pfam domain/function: PF00764 Arginosuc_synth [H]

EC number: =6.3.4.5 [H]

Molecular weight: Translated: 43970; Mature: 43839

Theoretical pI: Translated: 6.25; Mature: 6.25

Prosite motif: PS00564 ARGININOSUCCIN_SYN_1 ; PS00565 ARGININOSUCCIN_SYN_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
2.0 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSNKNIVLAFSGGLDTSFCIPYLKEQGYAVHTVFADTGGVDEDERDFIEKRAAELGVASH
CCCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
LTVDGGPAIWDGFVKQLVWAGEAYQGQYPLLVSDRYLIVDAVLQRADALGTCAVAHGCTG
EEECCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
MGNDQVRFDLAIKAQGDYTIIAPIREIQKEHTQTRLYEQKYLEERGFGVRAKQKNYTINE
CCCCEEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEECC
NLLGITLSGGEIDKWEAPGEGARGWCAPRSAWPTDPLTVAIKFVEGEAVAVDGKPLSGPQ
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCHH
ILMKLNKLFASYGVGRGIYTGDTVIGLKGRIVYEAPGLTALLTAHRALEDAVLTKQQNRF
HHHHHHHHHHHHCCCCCEECCCEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
KPHIARKWVELVYEGFFHDPLKTDLETFLKSSQANVNGEIVLETRGGRVDAVAVRSPHIL
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCEE
TSKGVTYAQTADWGIEEAEGFIKLFGMSSTLYAHVNRSLRS
ECCCCEEEECCCCCHHHHCCEEEEECCCHHHHHHHHHHHCC
>Mature Secondary Structure 
SNKNIVLAFSGGLDTSFCIPYLKEQGYAVHTVFADTGGVDEDERDFIEKRAAELGVASH
CCCCEEEEEECCCCCHHHHHHHHCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCEE
LTVDGGPAIWDGFVKQLVWAGEAYQGQYPLLVSDRYLIVDAVLQRADALGTCAVAHGCTG
EEECCCHHHHHHHHHHHHHCCCCCCCCCCEEECCCHHHHHHHHHHHHHHHHHHHHHCCCC
MGNDQVRFDLAIKAQGDYTIIAPIREIQKEHTQTRLYEQKYLEERGFGVRAKQKNYTINE
CCCCEEEEEEEEEECCCEEEEHHHHHHHHHHHHHHHHHHHHHHHCCCCEEECCCCCEECC
NLLGITLSGGEIDKWEAPGEGARGWCAPRSAWPTDPLTVAIKFVEGEAVAVDGKPLSGPQ
CEEEEEEECCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEEEECCCEEEECCCCCCCHH
ILMKLNKLFASYGVGRGIYTGDTVIGLKGRIVYEAPGLTALLTAHRALEDAVLTKQQNRF
HHHHHHHHHHHHCCCCCEECCCEEEEECCEEEEECCCHHHHHHHHHHHHHHHHHHHHHCC
KPHIARKWVELVYEGFFHDPLKTDLETFLKSSQANVNGEIVLETRGGRVDAVAVRSPHIL
CHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCCCCCEEEEEECCCEEEEEEECCCCEE
TSKGVTYAQTADWGIEEAEGFIKLFGMSSTLYAHVNRSLRS
ECCCCEEEECCCCCHHHHCCEEEEECCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10910347 [H]