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The map label for this gene is btuC [C]

Identifier: 170757839

GI number: 170757839

Start: 383960

End: 385078

Strand: Direct

Name: btuC [C]

Synonym: CLD_0448

Alternate gene names: 170757839

Gene position: 383960-385078 (Clockwise)

Preceding gene: 170756589

Following gene: 170755860

Centisome position: 9.7

GC content: 34.76

Gene sequence:

>1119_bases
ATGTTACAAACAGGAAAAGTAGGAGTAGCAGAATCCAATACAGGGAATTATGGGTGTACTTTTAAAAAACATTCTCTGTT
TACTACAATAATTATTGGTTTAGTTACTATCCTTATATTATCTATCATAATTTCAGTATCAATAGGACAAGTATCTATTC
CATTCAGCCAATCTTATAGAATATTAATCTATAAATTAACTGGATTACAAACTGGTAATTTAGATCAATTTATGAATGGA
ATGTTTGAGGAGATTATTTGGCAAATTCGTTTTCCTAGAGTGTTATTGGCTATGATTGCAGGAATTGGGCTTACATTATG
CGGTGTAGTTATGCAGGCTTCTGTGCAAAATCCTTTAGCTGATCCTTATATATTAGGAATTTCTTCTGGTGCTTCATTAG
GAGCAACATTTTCAATTATGATTGGATTTGGTGTTGCAGGTACTTTAAGTGAACTTGGAGTTGCTTTTTGGGCATTTATT
GGCGCATTTGGTGCTGGGGCTTTAGTTATGGGGCTTGCCAGTATTGGTGGAAAAATGTCCTCTGTAAAATTAGTACTTGC
TGGAACTGTTATCAATGCTTTATGCAATGCAATTTCAAGTTTTATTGTTTATTTTGCTAAGGATGCAGAAGGAATTCGTT
CTGTAACATTTTGGACTATGGGAAGTCTAACCTCTGCACAGTGGGGAAAGCTTCCTATTATTACTACCATTGTAATGTTA
GCTGTGGTGCTATTTTTATCTCAGGCAAGAATAATGAATACTATGATGATGGGAGAAGAGACGGCGGTTACTTTGGGAAT
AAACCTTAATTTTTATAGGAGACTTTATATGGTGATTTCAGTTGCGGTAACGGGTGTTATAGTAGCAACTTGTGGGATTA
TAGGATTTGTGGGATTAATTGTTCCTCATATTGTTAGAAGCATTGTTGGCTCGGATAACAAACGACTTTTACCAACAAGT
ATCCTATTTAGTGCAATATTTTTAATTTGGGCAGATATTTTTGCTAGAACAATTATTCCAAATGGAGAACTACCAATTGG
CATTATTACATCTCTTCTTGGAGCACCTGTGTTTATGTACATGCTAGTAAAGAGAAGTTATGGATTTGGAGGTAAGTAA

Upstream 100 bases:

>100_bases
TAGACTACACCAATGCAATACGTGGAAGCCTTGAACTTTCAGATTTGTATGAAGATGTTGCAAAATTTATTCATCCTGAA
CTATTTGGAGGAAATTAGTT

Downstream 100 bases:

>100_bases
ATTGAATTTAAAAGTAGACAATATATTTGTTACTTTATCAGGAAGAAAAGTTGTAAAGGATATTTCTCTACAGGTTGATG
ATGGAAAATTTGTTGGGATT

Product: iron chelate ABC transporter permease protein

Products: ADP; phosphate; cob(I)alamin [Cytoplasm] [C]

Alternate protein names: NA

Number of amino acids: Translated: 372; Mature: 372

Protein sequence:

>372_residues
MLQTGKVGVAESNTGNYGCTFKKHSLFTTIIIGLVTILILSIIISVSIGQVSIPFSQSYRILIYKLTGLQTGNLDQFMNG
MFEEIIWQIRFPRVLLAMIAGIGLTLCGVVMQASVQNPLADPYILGISSGASLGATFSIMIGFGVAGTLSELGVAFWAFI
GAFGAGALVMGLASIGGKMSSVKLVLAGTVINALCNAISSFIVYFAKDAEGIRSVTFWTMGSLTSAQWGKLPIITTIVML
AVVLFLSQARIMNTMMMGEETAVTLGINLNFYRRLYMVISVAVTGVIVATCGIIGFVGLIVPHIVRSIVGSDNKRLLPTS
ILFSAIFLIWADIFARTIIPNGELPIGIITSLLGAPVFMYMLVKRSYGFGGK

Sequences:

>Translated_372_residues
MLQTGKVGVAESNTGNYGCTFKKHSLFTTIIIGLVTILILSIIISVSIGQVSIPFSQSYRILIYKLTGLQTGNLDQFMNG
MFEEIIWQIRFPRVLLAMIAGIGLTLCGVVMQASVQNPLADPYILGISSGASLGATFSIMIGFGVAGTLSELGVAFWAFI
GAFGAGALVMGLASIGGKMSSVKLVLAGTVINALCNAISSFIVYFAKDAEGIRSVTFWTMGSLTSAQWGKLPIITTIVML
AVVLFLSQARIMNTMMMGEETAVTLGINLNFYRRLYMVISVAVTGVIVATCGIIGFVGLIVPHIVRSIVGSDNKRLLPTS
ILFSAIFLIWADIFARTIIPNGELPIGIITSLLGAPVFMYMLVKRSYGFGGK
>Mature_372_residues
MLQTGKVGVAESNTGNYGCTFKKHSLFTTIIIGLVTILILSIIISVSIGQVSIPFSQSYRILIYKLTGLQTGNLDQFMNG
MFEEIIWQIRFPRVLLAMIAGIGLTLCGVVMQASVQNPLADPYILGISSGASLGATFSIMIGFGVAGTLSELGVAFWAFI
GAFGAGALVMGLASIGGKMSSVKLVLAGTVINALCNAISSFIVYFAKDAEGIRSVTFWTMGSLTSAQWGKLPIITTIVML
AVVLFLSQARIMNTMMMGEETAVTLGINLNFYRRLYMVISVAVTGVIVATCGIIGFVGLIVPHIVRSIVGSDNKRLLPTS
ILFSAIFLIWADIFARTIIPNGELPIGIITSLLGAPVFMYMLVKRSYGFGGK

Specific function: Probably part of a binding-protein-dependent transport system. Probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0609

COG function: function code P; ABC-type Fe3+-siderophore transport system, permease component

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1788004, Length=286, Percent_Identity=36.013986013986, Blast_Score=155, Evalue=3e-39,
Organism=Escherichia coli, GI1790740, Length=322, Percent_Identity=32.6086956521739, Blast_Score=151, Evalue=5e-38,
Organism=Escherichia coli, GI1790741, Length=290, Percent_Identity=31.7241379310345, Blast_Score=135, Evalue=6e-33,
Organism=Escherichia coli, GI1786805, Length=293, Percent_Identity=32.7645051194539, Blast_Score=128, Evalue=6e-31,
Organism=Escherichia coli, GI1786347, Length=236, Percent_Identity=32.6271186440678, Blast_Score=96, Evalue=5e-21,
Organism=Escherichia coli, GI1786804, Length=279, Percent_Identity=28.3154121863799, Blast_Score=90, Evalue=2e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000522 [H]

Pfam domain/function: PF01032 FecCD [H]

EC number: NA

Molecular weight: Translated: 39659; Mature: 39659

Theoretical pI: Translated: 9.83; Mature: 9.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.6 %Met     (Translated Protein)
5.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.6 %Met     (Mature Protein)
5.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLQTGKVGVAESNTGNYGCTFKKHSLFTTIIIGLVTILILSIIISVSIGQVSIPFSQSYR
CCCCCCCCCEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCE
ILIYKLTGLQTGNLDQFMNGMFEEIIWQIRFPRVLLAMIAGIGLTLCGVVMQASVQNPLA
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPYILGISSGASLGATFSIMIGFGVAGTLSELGVAFWAFIGAFGAGALVMGLASIGGKMS
CCEEEEECCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SVKLVLAGTVINALCNAISSFIVYFAKDAEGIRSVTFWTMGSLTSAQWGKLPIITTIVML
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
AVVLFLSQARIMNTMMMGEETAVTLGINLNFYRRLYMVISVAVTGVIVATCGIIGFVGLI
HHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPHIVRSIVGSDNKRLLPTSILFSAIFLIWADIFARTIIPNGELPIGIITSLLGAPVFMY
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
MLVKRSYGFGGK
HHHHHCCCCCCC
>Mature Secondary Structure
MLQTGKVGVAESNTGNYGCTFKKHSLFTTIIIGLVTILILSIIISVSIGQVSIPFSQSYR
CCCCCCCCCEECCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCE
ILIYKLTGLQTGNLDQFMNGMFEEIIWQIRFPRVLLAMIAGIGLTLCGVVMQASVQNPLA
EEEEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
DPYILGISSGASLGATFSIMIGFGVAGTLSELGVAFWAFIGAFGAGALVMGLASIGGKMS
CCEEEEECCCCCCCHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHH
SVKLVLAGTVINALCNAISSFIVYFAKDAEGIRSVTFWTMGSLTSAQWGKLPIITTIVML
HHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHCCCCCCCCCCCCCHHHHHHHHH
AVVLFLSQARIMNTMMMGEETAVTLGINLNFYRRLYMVISVAVTGVIVATCGIIGFVGLI
HHHHHHHHHHHHHHHHCCCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VPHIVRSIVGSDNKRLLPTSILFSAIFLIWADIFARTIIPNGELPIGIITSLLGAPVFMY
HHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHH
MLVKRSYGFGGK
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; cob(I)alamin [Periplasm]; H2O [C]

Specific reaction: ATP + cob(I)alamin [Periplasm] + H2O = ADP + phosphate + cob(I)alamin [Cytoplasm] [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 8688087 [H]