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The map label for this gene is ykvY [H]

Identifier: 170757630

GI number: 170757630

Start: 424416

End: 425498

Strand: Direct

Name: ykvY [H]

Synonym: CLD_0408

Alternate gene names: 170757630

Gene position: 424416-425498 (Clockwise)

Preceding gene: 170754476

Following gene: 170756566

Centisome position: 10.72

GC content: 30.66

Gene sequence:

>1083_bases
ATGAACCAAGAAAGACTTAATAAAGTTTTAGAGGGAATGAAAGAAAGAGAAATTCCTCAAATGTTGATTTCAGATGCACC
AGCTATATTTTATTTAACAGGAAAATGGATTCATACAGGAGAAAGGCTAATAGCTCTTTACCTTAATGAAAATGGGAACC
ATAAATTATTTATAAATGAATTATTTCCAGTAACTGAAGACTTAGGAGTAGAAAAAGTTTGGTTTAATGATAACCAAGAT
GGAGTAGAAATAATTTCTAAATATGTTGAAAAAGATAAAGTAATGGGTGTAGATAAAAACTGGCCAGCACGTTTTTTATT
AAGACTTATGGAATTACAAGGCGGAAGCAAATTTGTTAATGATTCAATAATAATAGATAGAGCAAGAATGTTCAAAGATG
AAAAAGAAAAAGAATTAATGAGAGCTTCATCAAAAGCAAATGACGCTGCTATGGAAAAATTATATAACTTATTTAAAGAA
AATCAAGATTTATCAGAAAAAGAAGTTGGTGAAAGACTTGCAAAAATTTATAGTGACTTAGGTGCAGAAAGATTCTCATT
TGATCCAATAGTAGGATATGGAGCAAATGCAGCAGATCCACATCATGAAAATGATGGTTCTAAACTTAAAGAAGGAGATT
GCATAGTTTTAGATATAGGTTGTGTAAAAGATTCTTATTGTTCAGATATGACTAGAGTTTTCTTCTATAAAAGTGTTCCA
GAACATTCAAAAAAAGTTTATGATACAGTAGTAGCTGCTAATATGGCAGGTATAGCTGCTGTTAAACCAGGAGTAAGATT
CTGTGATATAGATAAAGCTTCTAGAGATGTTATAGAAAAAGCTGGATACGGAAAATACTTTACTCATAGAACAGGACACT
CAATTGGTATAGAAGATCACGATTTAGGAGACGTTTCAGCAGTTAACACTGAAGAAATAAAACCAGGAATGATATTCTCA
ATAGAACCAGGTATATACTTACCAGGTGAAGTTGGTGTTAGAATAGAAGACTTAGTTTTAGTAACAGAAGACGGTTGTGA
AGTTTTAAATAAATATAGTAAAGAGTTAACTATAATAGAATAA

Upstream 100 bases:

>100_bases
GGCTATCTAAAAGGTAGTCTTTTTCACAAATAGATATTGATTTTGTTTCTCTTTTATATAGAGAATAAAAAAATAAATAT
AAATTTAGGAGTGGATTTTT

Downstream 100 bases:

>100_bases
ATTTTTTATATAAGTATCCTATAAACAGACTTCTTGGCTTTAGAGGGAGCTTTTACTCCCACTAAAGCTTAGAAATCGTT
ATCCAGGGACATAGCCGCTC

Product: M24 family metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 360; Mature: 360

Protein sequence:

>360_residues
MNQERLNKVLEGMKEREIPQMLISDAPAIFYLTGKWIHTGERLIALYLNENGNHKLFINELFPVTEDLGVEKVWFNDNQD
GVEIISKYVEKDKVMGVDKNWPARFLLRLMELQGGSKFVNDSIIIDRARMFKDEKEKELMRASSKANDAAMEKLYNLFKE
NQDLSEKEVGERLAKIYSDLGAERFSFDPIVGYGANAADPHHENDGSKLKEGDCIVLDIGCVKDSYCSDMTRVFFYKSVP
EHSKKVYDTVVAANMAGIAAVKPGVRFCDIDKASRDVIEKAGYGKYFTHRTGHSIGIEDHDLGDVSAVNTEEIKPGMIFS
IEPGIYLPGEVGVRIEDLVLVTEDGCEVLNKYSKELTIIE

Sequences:

>Translated_360_residues
MNQERLNKVLEGMKEREIPQMLISDAPAIFYLTGKWIHTGERLIALYLNENGNHKLFINELFPVTEDLGVEKVWFNDNQD
GVEIISKYVEKDKVMGVDKNWPARFLLRLMELQGGSKFVNDSIIIDRARMFKDEKEKELMRASSKANDAAMEKLYNLFKE
NQDLSEKEVGERLAKIYSDLGAERFSFDPIVGYGANAADPHHENDGSKLKEGDCIVLDIGCVKDSYCSDMTRVFFYKSVP
EHSKKVYDTVVAANMAGIAAVKPGVRFCDIDKASRDVIEKAGYGKYFTHRTGHSIGIEDHDLGDVSAVNTEEIKPGMIFS
IEPGIYLPGEVGVRIEDLVLVTEDGCEVLNKYSKELTIIE
>Mature_360_residues
MNQERLNKVLEGMKEREIPQMLISDAPAIFYLTGKWIHTGERLIALYLNENGNHKLFINELFPVTEDLGVEKVWFNDNQD
GVEIISKYVEKDKVMGVDKNWPARFLLRLMELQGGSKFVNDSIIIDRARMFKDEKEKELMRASSKANDAAMEKLYNLFKE
NQDLSEKEVGERLAKIYSDLGAERFSFDPIVGYGANAADPHHENDGSKLKEGDCIVLDIGCVKDSYCSDMTRVFFYKSVP
EHSKKVYDTVVAANMAGIAAVKPGVRFCDIDKASRDVIEKAGYGKYFTHRTGHSIGIEDHDLGDVSAVNTEEIKPGMIFS
IEPGIYLPGEVGVRIEDLVLVTEDGCEVLNKYSKELTIIE

Specific function: Unknown

COG id: COG0006

COG function: function code E; Xaa-Pro aminopeptidase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the peptidase M24B family [H]

Homologues:

Organism=Homo sapiens, GI11559925, Length=268, Percent_Identity=26.1194029850746, Blast_Score=90, Evalue=3e-18,
Organism=Homo sapiens, GI149589008, Length=323, Percent_Identity=27.2445820433437, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI260593665, Length=323, Percent_Identity=27.2445820433437, Blast_Score=83, Evalue=4e-16,
Organism=Homo sapiens, GI260593663, Length=267, Percent_Identity=26.5917602996255, Blast_Score=73, Evalue=5e-13,
Organism=Escherichia coli, GI1788728, Length=238, Percent_Identity=40.3361344537815, Blast_Score=176, Evalue=3e-45,
Organism=Escherichia coli, GI1789275, Length=267, Percent_Identity=22.8464419475655, Blast_Score=92, Evalue=5e-20,
Organism=Caenorhabditis elegans, GI17508215, Length=374, Percent_Identity=26.7379679144385, Blast_Score=76, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI17509539, Length=234, Percent_Identity=27.7777777777778, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17507601, Length=256, Percent_Identity=28.125, Blast_Score=65, Evalue=4e-11,
Organism=Saccharomyces cerevisiae, GI6320922, Length=245, Percent_Identity=23.265306122449, Blast_Score=67, Evalue=5e-12,
Organism=Drosophila melanogaster, GI19920384, Length=268, Percent_Identity=26.1194029850746, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000587
- InterPro:   IPR001714
- InterPro:   IPR000994
- InterPro:   IPR001131 [H]

Pfam domain/function: PF01321 Creatinase_N; PF00557 Peptidase_M24 [H]

EC number: 3.4.-.- [C]

Molecular weight: Translated: 40609; Mature: 40609

Theoretical pI: Translated: 4.79; Mature: 4.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
3.1 %Met     (Mature Protein)
4.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNQERLNKVLEGMKEREIPQMLISDAPAIFYLTGKWIHTGERLIALYLNENGNHKLFINE
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEECCCEEEEEEEECCCCEEEEECC
LFPVTEDLGVEKVWFNDNQDGVEIISKYVEKDKVMGVDKNWPARFLLRLMELQGGSKFVN
CCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCEECC
DSIIIDRARMFKDEKEKELMRASSKANDAAMEKLYNLFKENQDLSEKEVGERLAKIYSDL
CCEEEHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GAERFSFDPIVGYGANAADPHHENDGSKLKEGDCIVLDIGCVKDSYCSDMTRVFFYKSVP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
EHSKKVYDTVVAANMAGIAAVKPGVRFCDIDKASRDVIEKAGYGKYFTHRTGHSIGIEDH
HHHHHHHHHHHHHHHCCHHHCCCCCEEECCCHHHHHHHHHCCCCCCEECCCCCCCCCCCC
DLGDVSAVNTEEIKPGMIFSIEPGIYLPGEVGVRIEDLVLVTEDGCEVLNKYSKELTIIE
CCCCCCCCCHHHCCCCEEEEECCCEECCCCCCCEEEEEEEEECCHHHHHHHHCCCEEEEC
>Mature Secondary Structure
MNQERLNKVLEGMKEREIPQMLISDAPAIFYLTGKWIHTGERLIALYLNENGNHKLFINE
CCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCEEECCCEEEEEEEECCCCEEEEECC
LFPVTEDLGVEKVWFNDNQDGVEIISKYVEKDKVMGVDKNWPARFLLRLMELQGGSKFVN
CCCCHHHCCCEEEEECCCCCHHHHHHHHHHHHHEECCCCCCHHHHHHHHHHHCCCCEECC
DSIIIDRARMFKDEKEKELMRASSKANDAAMEKLYNLFKENQDLSEKEVGERLAKIYSDL
CCEEEHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHH
GAERFSFDPIVGYGANAADPHHENDGSKLKEGDCIVLDIGCVKDSYCSDMTRVFFYKSVP
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHHCCC
EHSKKVYDTVVAANMAGIAAVKPGVRFCDIDKASRDVIEKAGYGKYFTHRTGHSIGIEDH
HHHHHHHHHHHHHHHCCHHHCCCCCEEECCCHHHHHHHHHCCCCCCEECCCCCCCCCCCC
DLGDVSAVNTEEIKPGMIFSIEPGIYLPGEVGVRIEDLVLVTEDGCEVLNKYSKELTIIE
CCCCCCCCCHHHCCCCEEEEECCCEECCCCCCCEEEEEEEEECCHHHHHHHHCCCEEEEC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]