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The map label for this gene is dhaKL

Identifier: 170757123

GI number: 170757123

Start: 1083603

End: 1085363

Strand: Reverse

Name: dhaKL

Synonym: CLD_3590

Alternate gene names: 170757123

Gene position: 1085363-1083603 (Counterclockwise)

Preceding gene: 170756058

Following gene: 170754965

Centisome position: 27.42

GC content: 33.28

Gene sequence:

>1761_bases
ATGAAAAAGATAATAAATAGACCTGAAACTGTAGTTATGGAGATGTGTAATGGAATAGCTATGGCACATCCTGAACTAGA
GTTTGTTAGAAAATATAAAGTAATGAAAAAAAAGAATATAAACAAAAATAAAGTTAGCTTAATTAGTGGTGGTGGAAGTG
GTCACGAACCAGCTCATGCCGGATTTATTGGAAAGGGAATGTTAGATGCAGCAGTATGCGGAGATATATTCGCTTCTCCC
TCTCAAATTCAAGTATATAAAGCTATAAAAGCTACAGCTAGCGAAAAAGGAACATTATTAATTATAAAAAACTATAGTGG
AGATATAATGAATTTTAAAAATGCTGCCCATTTAGCAAGTGAGGATGGTATTAAAGTTGACTATGTTAAAGTTGATGACG
ATATAGCTGTTGAAGATAGCTTATATACTGTAGGACGTAGAGGAGTTGCAGGTACTGTACTAGTTCATAAAATAGCAGGT
GCAGCTGCAGAATTAGGCTTTTCATTAGAAAAAGTTAAATCAATTGCCCAAAAAGCTGTTTCTAATGTTAGAAGCTTAGG
TTTTGCTTTCTCTTCTTGTACAGTTCCAGCTAAAAGAACTCCAACTTTTCAATTAGCAGAGGATGAAATGGAATTTGGTG
TTGGAATCCATGGCGAACCTGGAATAGTAAGAGAAAAGATTGCTACAGCAGATGAATTAGCTAAAAAAATTGTTGATTCC
ATATTAAAAGACATGAAAATAGATGGATCAAATAATGAAGAAGTAGCGTTATTAATTAATGGTTTTGGTGCTACCCCTCT
ACAAGAATTATATCTATTTAATAATTCAGTTACTGCTGAGCTAGCAAAGAAAAATATAAAAATAAATAGAACATTTGTAG
GAAACTATATGACTAGTATAGATATGGAGGGCGCTTCAGTATCTATCATGAAATTAGATGATGAGCTCAAAGAATTACTA
TCAAAAGAAAGTGATACTCCTGCATTTAAAGTTTCAGGACCAGTTGAATCAGTTGAATATATCAGCTTAGAAGATAATAA
TGATATTGAAAATGAAGTTAGTTTTGATTTGGAAACTTGTGATTGTCATAGCGAAATAAAAGATAAAAAAATCACTTTAG
ATAATATGATTTATATTATAGATAAGATGAGTGAAGTAATAATAGCAAATGAAGTTCACTTCTGTGAATTAGATTCTCAT
GCTGGTGATGGTGATTTTGGTATGAGTGTAGCAAAAGGCTTCAAACAATTAAAAAGAGACTGGAAACATATTCTTAAAGA
AGATAATATGAATATTGGTAAATTCTTAAACGAATGCTCTTTAATAATTATGGAACATTGTGGTGGAGCATCAGGCCCAA
TATGGGGATCAGCATTTAGATCCGCTGGAAAACAAGTTGGAGATAAAAAAGAATTATCAGTTTCAGATTTTGCTGAAATG
ATGCAAGCAGCTGTAAAAGGAATTCAAGCTACAGGAGAGCGTTCTTTTGGAAGAGGAGCAGTAGTTGGAGATAAAACTTT
AATTGACGCATTAGTTCCTTGTGCTGATTTGTGGAGTGAAAGTGCTAATAACAATACTTCTATACATGAAGCCTTCCAAA
AAGGTGCCGCTGCAGCAGTTAAAGGTGCAAAAATGACTGAAGAAATAGTAGCTCGTATGGGTAGAGCAGGTACAGTTGGT
GAAAGAAGCATTGGTTACCCAGATGCAGGCGCTTATGGATTAGGAGTTATATTTACAGAAATATCAAATTCATTAAAATA
A

Upstream 100 bases:

>100_bases
TCTATGCCATTTAAGGTAACTCCAGAAGCAGTAGCAGCAGCAATAATAACAGCAGATACTTTAGGTAAAGAATATAAATC
AAATAAATAGAGGTGTAAAC

Downstream 100 bases:

>100_bases
GCCTTCTAATATTATAATAGCTCATACAATATTATAATTTAAAATTTAACCTAAAAACTCCAGTAAACATCTTATTTTTT
ACTGGGGTTTTTATTTTTAC

Product: dihydroxyacetone kinase

Products: ADP; glycerone phosphate

Alternate protein names: NA

Number of amino acids: Translated: 586; Mature: 586

Protein sequence:

>586_residues
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHAGFIGKGMLDAAVCGDIFASP
SQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLASEDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAG
AAAELGFSLEKVKSIAQKAVSNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKIATADELAKKIVDS
ILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSIDMEGASVSIMKLDDELKELL
SKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETCDCHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSH
AGDGDFGMSVAKGFKQLKRDWKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAEM
MQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAVKGAKMTEEIVARMGRAGTVG
ERSIGYPDAGAYGLGVIFTEISNSLK

Sequences:

>Translated_586_residues
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHAGFIGKGMLDAAVCGDIFASP
SQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLASEDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAG
AAAELGFSLEKVKSIAQKAVSNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKIATADELAKKIVDS
ILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSIDMEGASVSIMKLDDELKELL
SKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETCDCHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSH
AGDGDFGMSVAKGFKQLKRDWKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAEM
MQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAVKGAKMTEEIVARMGRAGTVG
ERSIGYPDAGAYGLGVIFTEISNSLK
>Mature_586_residues
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHAGFIGKGMLDAAVCGDIFASP
SQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLASEDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAG
AAAELGFSLEKVKSIAQKAVSNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKIATADELAKKIVDS
ILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSIDMEGASVSIMKLDDELKELL
SKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETCDCHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSH
AGDGDFGMSVAKGFKQLKRDWKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAEM
MQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAVKGAKMTEEIVARMGRAGTVG
ERSIGYPDAGAYGLGVIFTEISNSLK

Specific function: Dihydroxyacetone binding subunit of the dihydroxyacetone kinase, which is responsible for phosphorylating dihydroxyacetone [H]

COG id: COG2376

COG function: function code G; Dihydroxyacetone kinase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 DhaK domain [H]

Homologues:

Organism=Homo sapiens, GI20149621, Length=578, Percent_Identity=30.9688581314879, Blast_Score=278, Evalue=8e-75,
Organism=Escherichia coli, GI87081857, Length=352, Percent_Identity=43.1818181818182, Blast_Score=284, Evalue=9e-78,
Organism=Escherichia coli, GI1787449, Length=179, Percent_Identity=30.7262569832402, Blast_Score=87, Evalue=2e-18,
Organism=Caenorhabditis elegans, GI17565018, Length=583, Percent_Identity=31.5608919382504, Blast_Score=278, Evalue=8e-75,
Organism=Saccharomyces cerevisiae, GI6321055, Length=600, Percent_Identity=32.5, Blast_Score=236, Evalue=6e-63,
Organism=Saccharomyces cerevisiae, GI6323570, Length=593, Percent_Identity=33.0522765598651, Blast_Score=234, Evalue=3e-62,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004006
- InterPro:   IPR012736 [H]

Pfam domain/function: PF02733 Dak1 [H]

EC number: 2.7.1.29

Molecular weight: Translated: 63283; Mature: 63283

Theoretical pI: Translated: 5.45; Mature: 5.45

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
GFIGKGMLDAAVCGDIFASPSQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLAS
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHCC
EDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAGAAAELGFSLEKVKSIAQKAV
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKIATADELAKKIVDS
HHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSI
HHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHCCCEEEEEEECCHHEEE
DMEGASVSIMKLDDELKELLSKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETC
ECCCCEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCCCCCHHEECEECC
DCHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSHAGDGDFGMSVAKGFKQLKRD
CCHHHHCCCEEEHHHHHHHHHHHHHHHEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
WKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAEM
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHH
MQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAV
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHH
KGAKMTEEIVARMGRAGTVGERSIGYPDAGAYGLGVIFTEISNSLK
HCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKKIINRPETVVMEMCNGIAMAHPELEFVRKYKVMKKKNINKNKVSLISGGGSGHEPAHA
CCCCCCCHHHHHHHHHCCCEECCCHHHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCCC
GFIGKGMLDAAVCGDIFASPSQIQVYKAIKATASEKGTLLIIKNYSGDIMNFKNAAHLAS
CCCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHCC
EDGIKVDYVKVDDDIAVEDSLYTVGRRGVAGTVLVHKIAGAAAELGFSLEKVKSIAQKAV
CCCCEEEEEEECCCCEECCHHHHHCCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHH
SNVRSLGFAFSSCTVPAKRTPTFQLAEDEMEFGVGIHGEPGIVREKIATADELAKKIVDS
HHHHHHHHHHHCCCCCCCCCCCEEECCHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHH
ILKDMKIDGSNNEEVALLINGFGATPLQELYLFNNSVTAELAKKNIKINRTFVGNYMTSI
HHHHCCCCCCCCCEEEEEEECCCCCHHHHHHHHCCCHHHHHHHCCCEEEEEEECCHHEEE
DMEGASVSIMKLDDELKELLSKESDTPAFKVSGPVESVEYISLEDNNDIENEVSFDLETC
ECCCCEEEEEECCHHHHHHHHCCCCCCEEEECCCCCCEEEEEECCCCCCCCHHEECEECC
DCHSEIKDKKITLDNMIYIIDKMSEVIIANEVHFCELDSHAGDGDFGMSVAKGFKQLKRD
CCHHHHCCCEEEHHHHHHHHHHHHHHHEECCEEEEEECCCCCCCCCHHHHHHHHHHHHHH
WKHILKEDNMNIGKFLNECSLIIMEHCGGASGPIWGSAFRSAGKQVGDKKELSVSDFAEM
HHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCCCCCHHHHHHH
MQAAVKGIQATGERSFGRGAVVGDKTLIDALVPCADLWSESANNNTSIHEAFQKGAAAAV
HHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHCHHHHH
KGAKMTEEIVARMGRAGTVGERSIGYPDAGAYGLGVIFTEISNSLK
HCHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; glycerone

Specific reaction: ATP + glycerone = ADP + glycerone phosphate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11337471 [H]