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The map label for this gene is add

Identifier: 170756064

GI number: 170756064

Start: 1096034

End: 1097041

Strand: Reverse

Name: add

Synonym: CLD_3575

Alternate gene names: 170756064

Gene position: 1097041-1096034 (Counterclockwise)

Preceding gene: 170754293

Following gene: 170754218

Centisome position: 27.72

GC content: 29.66

Gene sequence:

>1008_bases
TTGAATTTTAAAAAACTTCCTAAAATAGAGTTACATTGCCATTTAGATGGTTCATTGAGAGTAGACACAATATTAGATAT
AGCTAAAAAAGATAATATCCCTCTTCCTAGCTATAATAAAAAGGAGCTTATAAATTATGTTTCCATAATGGATGACTGTA
ATTCCCTAGATGAATACTTAAATAAGTTTTTTATACCTAACAAAGTTATGCAAACAAAGGAAAATTTAAAAAGAATAGCA
TTTGAGTTATTAGAAGATGTTGCAGCAGATAATGTAAAATATATAGAAGTAAGATTTGCCCCTCTTTTACATGTTGAAAA
AGGATTAAATATTGAAGAAATTATAGAAAGTGTACTGGAAGGGATTAAAGAAGCCGAAAAGCTTTATGATATAAAAGGTA
ATTTAATATTAGGTTGTATGAGAAATATGGATATTCCTTCAGCCTTTGAAGTTGTAAAAAAAGGGGCCAAATTTATTGGA
AAAGGTGTTGTTGCTATAGACCTTTGTGCTGGTGAAGAACCCCATTTCCCAGGAAAATATATAGAAGTTTTAAAACTAGC
TAAAGAATATGGTTATAGAATAACTATCCATGCTGGAGAAGCTGGCGTAGGAGAAAATGTTTTAGAAGCTATAAATCTTT
TAAATGCTGAAAGAATAGGCCATGGAATATATATTAAAGATTGTGCTGAAGCTTATAAGCTTGTAAAAGAAAAAAATATT
CCACTGGAGATGTGTCCAACAAGTAATCTCCATACTAAAGCTTCTGAAAGCTATGAAGCCCATCCTTTTATGGATTTTCT
AAAAGATGGTATTAAGGTTACTATTAATACAGATAATATGACAGTATCTAATACTACCATAACAAAAGAACTAGAAATGC
TTAATAAGTTTTGTGGTTTGTCTATAGAAGATTATAAAATACTATATCTAAATGCAGTAGAGGCATCTTTTGCATCCTCT
GAAACAAAAGAAGTACTTAAATCATATGTTAAGGAAATTACGGCTTAA

Upstream 100 bases:

>100_bases
TTACACAAATTAAATAATAAATTATAATTAAGTTTAACATTTTTAATAGATCTATATTATAAGAAATTACCTTAATCGGT
AATAGCAAGGAGTGACTAAT

Downstream 100 bases:

>100_bases
AAGCTTTTAAATGTTAAGAATTAAAACAAGAAATACTTTTAGTCAATAGATAGCTATAAAAATAAAAAATACTAATATTT
GTGCCTTAATATTTCAGCTA

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 335; Mature: 335

Protein sequence:

>335_residues
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIA
FELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLEGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGAKFIG
KGVVAIDLCAGEEPHFPGKYIEVLKLAKEYGYRITIHAGEAGVGENVLEAINLLNAERIGHGIYIKDCAEAYKLVKEKNI
PLEMCPTSNLHTKASESYEAHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIEDYKILYLNAVEASFASS
ETKEVLKSYVKEITA

Sequences:

>Translated_335_residues
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIA
FELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLEGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGAKFIG
KGVVAIDLCAGEEPHFPGKYIEVLKLAKEYGYRITIHAGEAGVGENVLEAINLLNAERIGHGIYIKDCAEAYKLVKEKNI
PLEMCPTSNLHTKASESYEAHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIEDYKILYLNAVEASFASS
ETKEVLKSYVKEITA
>Mature_335_residues
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYLNKFFIPNKVMQTKENLKRIA
FELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLEGIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGAKFIG
KGVVAIDLCAGEEPHFPGKYIEVLKLAKEYGYRITIHAGEAGVGENVLEAINLLNAERIGHGIYIKDCAEAYKLVKEKNI
PLEMCPTSNLHTKASESYEAHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGLSIEDYKILYLNAVEASFASS
ETKEVLKSYVKEITA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=339, Percent_Identity=32.7433628318584, Blast_Score=174, Evalue=2e-43,
Organism=Homo sapiens, GI226693318, Length=340, Percent_Identity=24.4117647058824, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI61175224, Length=252, Percent_Identity=26.1904761904762, Blast_Score=76, Evalue=5e-14,
Organism=Escherichia coli, GI1787910, Length=327, Percent_Identity=33.0275229357798, Blast_Score=187, Evalue=1e-48,
Organism=Caenorhabditis elegans, GI32565969, Length=346, Percent_Identity=30.3468208092486, Blast_Score=147, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI17538512, Length=346, Percent_Identity=30.3468208092486, Blast_Score=146, Evalue=1e-35,
Organism=Caenorhabditis elegans, GI115537133, Length=326, Percent_Identity=27.3006134969325, Blast_Score=91, Evalue=7e-19,
Organism=Saccharomyces cerevisiae, GI6324188, Length=336, Percent_Identity=24.702380952381, Blast_Score=122, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24645260, Length=338, Percent_Identity=29.2899408284024, Blast_Score=108, Evalue=6e-24,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 37748; Mature: 37748

Theoretical pI: Translated: 5.34; Mature: 5.34

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.7 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYL
CCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NKFFIPNKVMQTKENLKRIAFELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHCCCCHHHHHHHHHH
GIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGAKFIGKGVVAIDLCAGEEPHFPGKY
HHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHH
IEVLKLAKEYGYRITIHAGEAGVGENVLEAINLLNAERIGHGIYIKDCAEAYKLVKEKNI
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCCC
PLEMCPTSNLHTKASESYEAHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGL
CEEECCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHCC
SIEDYKILYLNAVEASFASSETKEVLKSYVKEITA
CCCCEEEEEEEEHHHHHCCHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MNFKKLPKIELHCHLDGSLRVDTILDIAKKDNIPLPSYNKKELINYVSIMDDCNSLDEYL
CCCCCCCCEEEEEECCCCEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHH
NKFFIPNKVMQTKENLKRIAFELLEDVAADNVKYIEVRFAPLLHVEKGLNIEEIIESVLE
HHHCCCHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEEEEHHHHHHHCCCCHHHHHHHHHH
GIKEAEKLYDIKGNLILGCMRNMDIPSAFEVVKKGAKFIGKGVVAIDLCAGEEPHFPGKY
HHHHHHHHHHCCCCEEEEEHHCCCCCHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCHHH
IEVLKLAKEYGYRITIHAGEAGVGENVLEAINLLNAERIGHGIYIKDCAEAYKLVKEKNI
HHHHHHHHHCCCEEEEECCCCCCCHHHHHHHHHHHHHHHCCCEEHHHHHHHHHHHHHCCC
PLEMCPTSNLHTKASESYEAHPFMDFLKDGIKVTINTDNMTVSNTTITKELEMLNKFCGL
CEEECCCCCCCCCCCCCCCCCHHHHHHHCCEEEEEECCCEEECCCHHHHHHHHHHHHHCC
SIEDYKILYLNAVEASFASSETKEVLKSYVKEITA
CCCCEEEEEEEEHHHHHCCHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA