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The map label for this gene is pgi

Identifier: 170755564

GI number: 170755564

Start: 3545017

End: 3546369

Strand: Reverse

Name: pgi

Synonym: CLD_1244

Alternate gene names: 170755564

Gene position: 3546369-3545017 (Counterclockwise)

Preceding gene: 170755000

Following gene: 170756161

Centisome position: 89.59

GC content: 30.16

Gene sequence:

>1353_bases
ATGGAAAATTCTTTAAGTCTCGATTTGACAAAAACTAAACCTTATGTTGAGGAGCATGAAATACAATATTTAGAATCAAT
AATAAGAGAAATGGATAATACTCTTGGCAAAAAAACAGGTCCAGGAAATAAGTTTCTAGGTTGGATGGATTTACCTATAA
ATTATAATAAAGAAGAGTTTGCAAGAATAAAAAAGGCAGCAGAAAAAATAAAAAATACTTGTGATGTGTTTATTGTTATA
GGCATAGGAGGATCTTATCTAGGATCAAGAGCTGCTATAGAAATGATATCAAATACATTTTATAATAATTTAGATAAAAA
CCAAAGAACAGTGCCACAAATATATTTTGCAGGTAATAATATAAGTTCTACTTATATGGCTGATTTATTAGAATTAGTTA
AAGATAAAGATATATGTGTAAATGTAATATCTAAATCAGGTACAACTACAGAGCCAGCTATAGCTTTTAGAATATTTAAA
GAATTATTAGAAAAGAAGTATGGAAAAGAAGGAGCAAAAGAAAGAATATTTGCGACTACAGATGCAGCTAAAGGTGCTTT
AAGAACTTTAGCTGATTTAGAAGGCTATGAAACTTTTGTAATACCAGATGATGTAGGTGGAAGATTTTCAGTTCTAACTC
CAGTAGGATTATTACCTATAGCTGTATCTGGAATAGATGTAGATGAAATTATGAAAGGTGCAGCAGATGCTAGACAAGAA
TATTCTTCAGATAATATAGAAAAAAATCATGTGTATAGATATGTAGCAGTAAGAAATGCTTTGTATAGAAAAGGAAAGAC
CACAGAAATGTTAGTTAATTTTGAACCATGTCTACATTATTTTGGAGAATGGTGGAAACAACTATATGGAGAAAGTGAAG
GTAAAGATGGAAAGGGAATATTCCCAGCAGCAGCAGACTTTTCAACAGATTTACATTCCATGGGACAATATATACAAGAA
GGTTTAAGAAATATATTTGAAACATTTATAAATGTAGAAAATCCTAGAAAGTCAATTATAATAAAAGAAGATAAAGAGAA
TTTAGATGGACTTAACTTTTTAGCAGAGAAAGACATGGATTATGTAAATCATCAAGCGTTAAGAGGTACTGTTTTAGCAC
ACAATGATGGTGGTGTTCCAGCTATAGTATTAAATGTTCCAGAACTTTCAGCTTATTATTTTGGACAATTAGTATATTTC
TTTGAAAAAGCTTGTGGAATAAGTGGATATTTACAAGGAGTTAATCCCTTTGATCAACCAGGAGTAGAAGCATATAAAAA
GAATATGTTTGCTCTTTTAGGAAAACCAGGCTATGAAGATATGAAAGCTACATTAGAAGAAAGATTGAAGTAA

Upstream 100 bases:

>100_bases
GAGGATTCAGAAGATAATAGAATAATGAAAAAATGGCTGTTGAATTACTTCAACAGCTTTTTATATTAAAATGTAAATAA
TTACATTGGAGGTATTAAAC

Downstream 100 bases:

>100_bases
TAGAATTTTTATGAGAATATTAGTAGATGCAGATGCTTGCCCAGGAAGAAATATAATAGAACAAGTAGCTAAAAAATATA
AAATAGATGTTATGATGTTT

Product: glucose-6-phosphate isomerase

Products: NA

Alternate protein names: GPI; Phosphoglucose isomerase; PGI; Phosphohexose isomerase; PHI [H]

Number of amino acids: Translated: 450; Mature: 450

Protein sequence:

>450_residues
MENSLSLDLTKTKPYVEEHEIQYLESIIREMDNTLGKKTGPGNKFLGWMDLPINYNKEEFARIKKAAEKIKNTCDVFIVI
GIGGSYLGSRAAIEMISNTFYNNLDKNQRTVPQIYFAGNNISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFK
ELLEKKYGKEGAKERIFATTDAAKGALRTLADLEGYETFVIPDDVGGRFSVLTPVGLLPIAVSGIDVDEIMKGAADARQE
YSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGIFPAAADFSTDLHSMGQYIQE
GLRNIFETFINVENPRKSIIIKEDKENLDGLNFLAEKDMDYVNHQALRGTVLAHNDGGVPAIVLNVPELSAYYFGQLVYF
FEKACGISGYLQGVNPFDQPGVEAYKKNMFALLGKPGYEDMKATLEERLK

Sequences:

>Translated_450_residues
MENSLSLDLTKTKPYVEEHEIQYLESIIREMDNTLGKKTGPGNKFLGWMDLPINYNKEEFARIKKAAEKIKNTCDVFIVI
GIGGSYLGSRAAIEMISNTFYNNLDKNQRTVPQIYFAGNNISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFK
ELLEKKYGKEGAKERIFATTDAAKGALRTLADLEGYETFVIPDDVGGRFSVLTPVGLLPIAVSGIDVDEIMKGAADARQE
YSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGIFPAAADFSTDLHSMGQYIQE
GLRNIFETFINVENPRKSIIIKEDKENLDGLNFLAEKDMDYVNHQALRGTVLAHNDGGVPAIVLNVPELSAYYFGQLVYF
FEKACGISGYLQGVNPFDQPGVEAYKKNMFALLGKPGYEDMKATLEERLK
>Mature_450_residues
MENSLSLDLTKTKPYVEEHEIQYLESIIREMDNTLGKKTGPGNKFLGWMDLPINYNKEEFARIKKAAEKIKNTCDVFIVI
GIGGSYLGSRAAIEMISNTFYNNLDKNQRTVPQIYFAGNNISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFK
ELLEKKYGKEGAKERIFATTDAAKGALRTLADLEGYETFVIPDDVGGRFSVLTPVGLLPIAVSGIDVDEIMKGAADARQE
YSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGIFPAAADFSTDLHSMGQYIQE
GLRNIFETFINVENPRKSIIIKEDKENLDGLNFLAEKDMDYVNHQALRGTVLAHNDGGVPAIVLNVPELSAYYFGQLVYF
FEKACGISGYLQGVNPFDQPGVEAYKKNMFALLGKPGYEDMKATLEERLK

Specific function: Involved in glycolysis and in gluconeogenesis. [C]

COG id: COG0166

COG function: function code G; Glucose-6-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GPI family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71996708, Length=396, Percent_Identity=25, Blast_Score=77, Evalue=3e-14,
Organism=Caenorhabditis elegans, GI71996703, Length=396, Percent_Identity=25, Blast_Score=76, Evalue=3e-14,
Organism=Saccharomyces cerevisiae, GI6319673, Length=383, Percent_Identity=25.8485639686684, Blast_Score=80, Evalue=7e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001672
- InterPro:   IPR018189 [H]

Pfam domain/function: PF00342 PGI [H]

EC number: =5.3.1.9 [H]

Molecular weight: Translated: 50522; Mature: 50522

Theoretical pI: Translated: 5.08; Mature: 5.08

Prosite motif: PS00765 P_GLUCOSE_ISOMERASE_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.3 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MENSLSLDLTKTKPYVEEHEIQYLESIIREMDNTLGKKTGPGNKFLGWMDLPINYNKEEF
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHH
ARIKKAAEKIKNTCDVFIVIGIGGSYLGSRAAIEMISNTFYNNLDKNQRTVPQIYFAGNN
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
ISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFKELLEKKYGKEGAKERIFATT
CCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCEEEEC
DAAKGALRTLADLEGYETFVIPDDVGGRFSVLTPVGLLPIAVSGIDVDEIMKGAADARQE
HHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCCHHHHEECCCCHHHHHHHHHHHHHH
YSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGI
HCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCC
FPAAADFSTDLHSMGQYIQEGLRNIFETFINVENPRKSIIIKEDKENLDGLNFLAEKDMD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHCHH
YVNHQALRGTVLAHNDGGVPAIVLNVPELSAYYFGQLVYFFEKACGISGYLQGVNPFDQP
HHHHHHHHCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCC
GVEAYKKNMFALLGKPGYEDMKATLEERLK
CHHHHHHHHHHHHCCCCHHHHHHHHHHHCC
>Mature Secondary Structure
MENSLSLDLTKTKPYVEEHEIQYLESIIREMDNTLGKKTGPGNKFLGWMDLPINYNKEEF
CCCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCEEEEEECCCCCCHHHH
ARIKKAAEKIKNTCDVFIVIGIGGSYLGSRAAIEMISNTFYNNLDKNQRTVPQIYFAGNN
HHHHHHHHHHCCCCEEEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEECCC
ISSTYMADLLELVKDKDICVNVISKSGTTTEPAIAFRIFKELLEKKYGKEGAKERIFATT
CCHHHHHHHHHHHCCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCCCCHHCEEEEC
DAAKGALRTLADLEGYETFVIPDDVGGRFSVLTPVGLLPIAVSGIDVDEIMKGAADARQE
HHHHHHHHHHHHCCCCEEEEEECCCCCCEEECCCCCHHHHEECCCCHHHHHHHHHHHHHH
YSSDNIEKNHVYRYVAVRNALYRKGKTTEMLVNFEPCLHYFGEWWKQLYGESEGKDGKGI
HCCCCCCHHHHHHHHHHHHHHHHCCCCCEEEEEHHHHHHHHHHHHHHHCCCCCCCCCCCC
FPAAADFSTDLHSMGQYIQEGLRNIFETFINVENPRKSIIIKEDKENLDGLNFLAEKDMD
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHHHHHHHCHH
YVNHQALRGTVLAHNDGGVPAIVLNVPELSAYYFGQLVYFFEKACGISGYLQGVNPFDQP
HHHHHHHHCEEEEECCCCCCEEEEECCHHHHHHHHHHHHHHHHHCCHHHHHCCCCCCCCC
GVEAYKKNMFALLGKPGYEDMKATLEERLK
CHHHHHHHHHHHHCCCCHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA