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The map label for this gene is nadA

Identifier: 170755261

GI number: 170755261

Start: 1612519

End: 1613433

Strand: Reverse

Name: nadA

Synonym: CLD_3101

Alternate gene names: 170755261

Gene position: 1613433-1612519 (Counterclockwise)

Preceding gene: 170755086

Following gene: 170756082

Centisome position: 40.76

GC content: 29.84

Gene sequence:

>915_bases
ATGAAACCAAATTTAAAAGATAAAATAGCTCATTTAAAAAAAGAAAGAAATGCCATAATACTTGCTCACTATTATCAAAG
ACCTGAAATACAAGATATAGCAGATGCAGTAGGTGATTCTTACTACCTAAGTAAAGTAGCAAAGGATTGTAGTGAATCCA
CAATATTGTTTTGTGGGGTAAAATTTATGGCTGAAAGTGCTAAAATTCTTTCTCCTCATAAGACCGTACTTTTGCCTGTA
TTTGATGCTGGATGTCCAATGGCGGATATGATATGTAAAAAAGATGTATTAGACTTAAAGAAAGATCATCCTAATGCAAA
GGTAATATGCTATATAAACTCTTCTGCTGAAGTAAAGTCTGTATCTGATGTTTGTTGTACTTCATCAAATGCAATAAACA
TTATAAGAAACTTACCAGAAAAAAAAATAATCTTTATTCCAGACAAAAATTTAGGAGAATATGTACAATCCCAAGTACAG
GATAAAGAGATAATATTATGGAATGGTTTTTGCATAACCCACCACAAAGTAAGGTTGGGAGAAATAAAAAAAGTTAAGCG
CTTACATACTGATATAAAAGTTTTGTGCCATGGAGAATGTGAAAAAGAAATTCGCCATGCTTCCGATTTTGTAGGAAGTA
CAGGGGATATTATAAAATTTGCAACAGAAAGCAATAATAAAAAATTTTTAATAGTTACTGAAGAAGGGATTCTTCACCAG
TTAAAAATAAAAAATCCAGAAAAACAATTCTATTTCCCTGGAGAAGGAATGACCTGCATAAACATGAAAAAAACTTCTTT
AAAAAATGTCTATGATAGTCTTTTAAATTTAAATTATAAAATAGAATTAGATAAAAATTTAAGATTAAAGGCCTATGATG
CCCTTATAAATATGCATACTTTAGGAGGCAGATAA

Upstream 100 bases:

>100_bases
TATTTATGTATATACTTGATATTAATATTTTAGAATGATATATTTTATATATAAGTGTATATACACATGTAAAATATAGT
GTATACTTCGGGAGGATTAT

Downstream 100 bases:

>100_bases
CCATGAATCTTTATGCTGATGTCTTGATTGCAGGAAGCGGCGTAGCTGGATTATATTCAGCTTTAAATCTAAGAAAAGAC
TTAAAAATAGTATTAATCTC

Product: quinolinate synthetase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 304; Mature: 304

Protein sequence:

>304_residues
MKPNLKDKIAHLKKERNAIILAHYYQRPEIQDIADAVGDSYYLSKVAKDCSESTILFCGVKFMAESAKILSPHKTVLLPV
FDAGCPMADMICKKDVLDLKKDHPNAKVICYINSSAEVKSVSDVCCTSSNAINIIRNLPEKKIIFIPDKNLGEYVQSQVQ
DKEIILWNGFCITHHKVRLGEIKKVKRLHTDIKVLCHGECEKEIRHASDFVGSTGDIIKFATESNNKKFLIVTEEGILHQ
LKIKNPEKQFYFPGEGMTCINMKKTSLKNVYDSLLNLNYKIELDKNLRLKAYDALINMHTLGGR

Sequences:

>Translated_304_residues
MKPNLKDKIAHLKKERNAIILAHYYQRPEIQDIADAVGDSYYLSKVAKDCSESTILFCGVKFMAESAKILSPHKTVLLPV
FDAGCPMADMICKKDVLDLKKDHPNAKVICYINSSAEVKSVSDVCCTSSNAINIIRNLPEKKIIFIPDKNLGEYVQSQVQ
DKEIILWNGFCITHHKVRLGEIKKVKRLHTDIKVLCHGECEKEIRHASDFVGSTGDIIKFATESNNKKFLIVTEEGILHQ
LKIKNPEKQFYFPGEGMTCINMKKTSLKNVYDSLLNLNYKIELDKNLRLKAYDALINMHTLGGR
>Mature_304_residues
MKPNLKDKIAHLKKERNAIILAHYYQRPEIQDIADAVGDSYYLSKVAKDCSESTILFCGVKFMAESAKILSPHKTVLLPV
FDAGCPMADMICKKDVLDLKKDHPNAKVICYINSSAEVKSVSDVCCTSSNAINIIRNLPEKKIIFIPDKNLGEYVQSQVQ
DKEIILWNGFCITHHKVRLGEIKKVKRLHTDIKVLCHGECEKEIRHASDFVGSTGDIIKFATESNNKKFLIVTEEGILHQ
LKIKNPEKQFYFPGEGMTCINMKKTSLKNVYDSLLNLNYKIELDKNLRLKAYDALINMHTLGGR

Specific function: Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate [H]

COG id: COG0379

COG function: function code H; Quinolinate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the quinolinate synthase A family. Type 2 subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786964, Length=311, Percent_Identity=35.048231511254, Blast_Score=186, Evalue=2e-48,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003473
- InterPro:   IPR023066 [H]

Pfam domain/function: PF02445 NadA [H]

EC number: =2.5.1.72 [H]

Molecular weight: Translated: 34457; Mature: 34457

Theoretical pI: Translated: 8.83; Mature: 8.83

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

3.6 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
5.9 %Cys+Met (Translated Protein)
3.6 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
5.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKPNLKDKIAHLKKERNAIILAHYYQRPEIQDIADAVGDSYYLSKVAKDCSESTILFCGV
CCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEH
KFMAESAKILSPHKTVLLPVFDAGCPMADMICKKDVLDLKKDHPNAKVICYINSSAEVKS
HHHHCCHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHH
VSDVCCTSSNAINIIRNLPEKKIIFIPDKNLGEYVQSQVQDKEIILWNGFCITHHKVRLG
HHHHHHCCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECEEEEECCEEHH
EIKKVKRLHTDIKVLCHGECEKEIRHASDFVGSTGDIIKFATESNNKKFLIVTEEGILHQ
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCEEE
LKIKNPEKQFYFPGEGMTCINMKKTSLKNVYDSLLNLNYKIELDKNLRLKAYDALINMHT
EEECCCCCCEEECCCCEEEEECCHHHHHHHHHHHHCCCEEEEECCCCEEEEHHHHHHHCC
LGGR
CCCC
>Mature Secondary Structure
MKPNLKDKIAHLKKERNAIILAHYYQRPEIQDIADAVGDSYYLSKVAKDCSESTILFCGV
CCCCHHHHHHHHHHHCCEEEEEEECCCCCHHHHHHHHCCHHHHHHHHHHCCCCEEEEEEH
KFMAESAKILSPHKTVLLPVFDAGCPMADMICKKDVLDLKKDHPNAKVICYINSSAEVKS
HHHHCCHHHCCCCCEEEEEEECCCCCHHHHHHHHHHHHHHCCCCCCEEEEEECCCCCHHH
VSDVCCTSSNAINIIRNLPEKKIIFIPDKNLGEYVQSQVQDKEIILWNGFCITHHKVRLG
HHHHHHCCCCHHHHHHCCCCCEEEEECCCCHHHHHHHHCCCCEEEEEECEEEEECCEEHH
EIKKVKRLHTDIKVLCHGECEKEIRHASDFVGSTGDIIKFATESNNKKFLIVTEEGILHQ
HHHHHHHHHCCEEEEECCCHHHHHHHHHHHCCCCCCEEEEEECCCCCEEEEEECCCCEEE
LKIKNPEKQFYFPGEGMTCINMKKTSLKNVYDSLLNLNYKIELDKNLRLKAYDALINMHT
EEECCCCCCEEECCCCEEEEECCHHHHHHHHHHHHCCCEEEEECCCCEEEEHHHHHHHCC
LGGR
CCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA