Click here to switch to the map view.

The map label for this gene is groES

Identifier: 170754876

GI number: 170754876

Start: 3570614

End: 3570901

Strand: Reverse

Name: groES

Synonym: CLD_1224

Alternate gene names: 170754876

Gene position: 3570901-3570614 (Counterclockwise)

Preceding gene: 170755654

Following gene: 170756380

Centisome position: 90.21

GC content: 36.46

Gene sequence:

>288_bases
ATGAACATTAGACCACTTGGAGATAGAGTAGTAATTAAAAGAGTAGAAGCAGAGGAGACTACAAAAAGCGGAATAGTATT
ACCAGGAGCTGCAAAAGAAAAACCACAGGTTGCAGAAGTAATAGCTGTAGGACCTGGTGGATTGGTTGATGGAAAAGAAG
TTAAGATGGAATTAAAAGTAGGGGATAAGGTATTATTCTCAAAATATGCCGGTAATGAAGTGAAAATTGAGGGCGAAGAA
GTAACTATATTAAAGCAAGATGACATATTAGCAGTAGTTGAAGGTTAA

Upstream 100 bases:

>100_bases
TATTATAATAATTGTATTAGCACTCAATATTAATGAGTGCTAACAAATAAAAGGTAGTAATTATTTAAAATATAAAAAAA
TATTTTAAGGAGGGGTTTAA

Downstream 100 bases:

>100_bases
TTATATATTTTATTTAGGAGGTATGAGAAATGGCAAAAAGTTTATTGTTTGGGGAACAAGCTAGAAGATCAATGGAAGCT
GGTGTTGATAAGTTAGCTGA

Product: co-chaperonin GroES

Products: NA

Alternate protein names: GroES protein; Protein Cpn10

Number of amino acids: Translated: 95; Mature: 95

Protein sequence:

>95_residues
MNIRPLGDRVVIKRVEAEETTKSGIVLPGAAKEKPQVAEVIAVGPGGLVDGKEVKMELKVGDKVLFSKYAGNEVKIEGEE
VTILKQDDILAVVEG

Sequences:

>Translated_95_residues
MNIRPLGDRVVIKRVEAEETTKSGIVLPGAAKEKPQVAEVIAVGPGGLVDGKEVKMELKVGDKVLFSKYAGNEVKIEGEE
VTILKQDDILAVVEG
>Mature_95_residues
MNIRPLGDRVVIKRVEAEETTKSGIVLPGAAKEKPQVAEVIAVGPGGLVDGKEVKMELKVGDKVLFSKYAGNEVKIEGEE
VTILKQDDILAVVEG

Specific function: Binds to Cpn60 in the presence of Mg-ATP and suppresses the ATPase activity of the latter

COG id: COG0234

COG function: function code O; Co-chaperonin GroES (HSP10)

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GroES chaperonin family

Homologues:

Organism=Escherichia coli, GI1790585, Length=96, Percent_Identity=50, Blast_Score=82, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17555568, Length=94, Percent_Identity=38.2978723404255, Blast_Score=64, Evalue=2e-11,
Organism=Saccharomyces cerevisiae, GI6324594, Length=92, Percent_Identity=41.304347826087, Blast_Score=66, Evalue=8e-13,
Organism=Drosophila melanogaster, GI21356029, Length=96, Percent_Identity=40.625, Blast_Score=62, Evalue=6e-11,

Paralogues:

None

Copy number: 980 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). 5720 Molecules/Cell In: Early Stationary Phase, Rich Media (Based on E. coli). 1274 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): CH10_CLOB1 (A7FYP4)

Other databases:

- EMBL:   CP000726
- RefSeq:   YP_001385617.1
- ProteinModelPortal:   A7FYP4
- SMR:   A7FYP4
- STRING:   A7FYP4
- GeneID:   5397941
- GenomeReviews:   CP000726_GR
- KEGG:   cba:CLB_3355
- eggNOG:   COG0234
- HOGENOM:   HBG703377
- OMA:   QDRIIVK
- ProtClustDB:   PRK00364
- BioCyc:   CBOT441770:CLB_3355-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00580
- InterPro:   IPR020818
- InterPro:   IPR018369
- InterPro:   IPR011032
- Gene3D:   G3DSA:2.30.33.40
- PANTHER:   PTHR10772
- PRINTS:   PR00297
- SMART:   SM00883

Pfam domain/function: PF00166 Cpn10; SSF50129 GroES_like

EC number: NA

Molecular weight: Translated: 10141; Mature: 10141

Theoretical pI: Translated: 4.73; Mature: 4.73

Prosite motif: PS00681 CHAPERONINS_CPN10

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNIRPLGDRVVIKRVEAEETTKSGIVLPGAAKEKPQVAEVIAVGPGGLVDGKEVKMELKV
CCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEE
GDKVLFSKYAGNEVKIEGEEVTILKQDDILAVVEG
CCEEEEEECCCCEEEEECCEEEEEECCCEEEEEEC
>Mature Secondary Structure
MNIRPLGDRVVIKRVEAEETTKSGIVLPGAAKEKPQVAEVIAVGPGGLVDGKEVKMELKV
CCCCCCCCEEEEEEECCCCCCCCCEEECCCCCCCCCEEEEEEECCCCCCCCCEEEEEEEE
GDKVLFSKYAGNEVKIEGEEVTILKQDDILAVVEG
CCEEEEEECCCCEEEEECCEEEEEECCCEEEEEEC

PDB accession: NA

Resolution: NA

Structure class: Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA