Click here to switch to the map view.

The map label for this gene is mraY

Identifier: 170754316

GI number: 170754316

Start: 994770

End: 995723

Strand: Reverse

Name: mraY

Synonym: CLD_3682

Alternate gene names: 170754316

Gene position: 995723-994770 (Counterclockwise)

Preceding gene: 170756933

Following gene: 170756360

Centisome position: 25.16

GC content: 27.15

Gene sequence:

>954_bases
ATGAGTACTGTTATATATGCTGTACTATTCAGTTTTTTATTATCTACAATTACTAGCTTGTTGCTCATCCCATTATTTAA
AAAATTAAATTTAGGACAAAGCATTAAAAATGGAATTCCGATAAGCCATAAAAAGAAGGCTGGAACTCTTACATTTGGTG
GTATTATTTTCATTTTTTCATCAATAATAACAATGTTATTTATGATAAAAAATTATAATAAAGAACTCTTGCTTATAATA
TCTTCACTTATTGCTTTTGGACTTATAGGTTTCATTGATGATACTTTAAAGAAAATACATAAAAAAAATGAAGGATTAAC
TTCAAAAGGAAAAATGATTTTATTACTTTTTGTATCAAGTATTTTTGCCATTTATTCATACTATGATCCTTCAATTGGTT
CAATAATTATGTTTCCATTTACTAAAAAACTATTTGACTTAAGAATTTTATACATACCCTTTATTATTTTTTATTACGTA
TCAACAACTAATGCATTAAACTTAACAGACGGTTTAGACGGACTTGCTACTTCTATAACACTACTTGTAGTAACATTTTT
TACTTTTCTATCTTTTGGAATGGGGCATTATACATTATCAATTAGTTGCGGTTGTATAGCAGGGGCTTTATTGGGATTCT
TACGATATAATTGTTATCCTGCTAAAATAATTATGGGGGATACTGGTTCTTTAGCCCTTGGTGGTGCTATTGCAACAATA
GCTATGATACTCAAAAACCCATTTATTGTTATTATTGTCGGAGGAATTTATGTTATTGAAGCATTATCATCATTAATTCA
AATAGTATTTTTTAAACTATTTAGTAAACGTATTTTTAAAATGGCTCCTATTCATCACTCATTTGAGTTACATGGCTGGC
ATGAAACCAAAATAGTTTCAGTATTTTCTATAATAACAACAATTTTATGTCTCATTGGATTTCTATCTATGTAA

Upstream 100 bases:

>100_bases
AAAAATCAACGTTAGCTAAAACAAATCCAATTTTAAAGATTCCATATTGATAGGAGGGTTATTGACGGAAATAAAATATT
AAGTTTAGAAAGGATTTATT

Downstream 100 bases:

>100_bases
TTAACAGTATTACTTTTGAACCCAGCAAGCTTACTCCACTGATTAAAGCCTGAAAGTTGTAGATACTATCACAATAATAA
GTTATACTTACTATAGAAAA

Product: phospho-N-acetylmuramoyl-pentapeptide- transferase

Products: NA

Alternate protein names: UDP-MurNAc-pentapeptide phosphotransferase [H]

Number of amino acids: Translated: 317; Mature: 316

Protein sequence:

>317_residues
MSTVIYAVLFSFLLSTITSLLLIPLFKKLNLGQSIKNGIPISHKKKAGTLTFGGIIFIFSSIITMLFMIKNYNKELLLII
SSLIAFGLIGFIDDTLKKIHKKNEGLTSKGKMILLLFVSSIFAIYSYYDPSIGSIIMFPFTKKLFDLRILYIPFIIFYYV
STTNALNLTDGLDGLATSITLLVVTFFTFLSFGMGHYTLSISCGCIAGALLGFLRYNCYPAKIIMGDTGSLALGGAIATI
AMILKNPFIVIIVGGIYVIEALSSLIQIVFFKLFSKRIFKMAPIHHSFELHGWHETKIVSVFSIITTILCLIGFLSM

Sequences:

>Translated_317_residues
MSTVIYAVLFSFLLSTITSLLLIPLFKKLNLGQSIKNGIPISHKKKAGTLTFGGIIFIFSSIITMLFMIKNYNKELLLII
SSLIAFGLIGFIDDTLKKIHKKNEGLTSKGKMILLLFVSSIFAIYSYYDPSIGSIIMFPFTKKLFDLRILYIPFIIFYYV
STTNALNLTDGLDGLATSITLLVVTFFTFLSFGMGHYTLSISCGCIAGALLGFLRYNCYPAKIIMGDTGSLALGGAIATI
AMILKNPFIVIIVGGIYVIEALSSLIQIVFFKLFSKRIFKMAPIHHSFELHGWHETKIVSVFSIITTILCLIGFLSM
>Mature_316_residues
STVIYAVLFSFLLSTITSLLLIPLFKKLNLGQSIKNGIPISHKKKAGTLTFGGIIFIFSSIITMLFMIKNYNKELLLIIS
SLIAFGLIGFIDDTLKKIHKKNEGLTSKGKMILLLFVSSIFAIYSYYDPSIGSIIMFPFTKKLFDLRILYIPFIIFYYVS
TTNALNLTDGLDGLATSITLLVVTFFTFLSFGMGHYTLSISCGCIAGALLGFLRYNCYPAKIIMGDTGSLALGGAIATIA
MILKNPFIVIIVGGIYVIEALSSLIQIVFFKLFSKRIFKMAPIHHSFELHGWHETKIVSVFSIITTILCLIGFLSM

Specific function: First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan [H]

COG id: COG0472

COG function: function code M; UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 4 family. MraY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1786275, Length=331, Percent_Identity=37.1601208459215, Blast_Score=206, Evalue=2e-54,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000715
- InterPro:   IPR003524
- InterPro:   IPR018480 [H]

Pfam domain/function: PF00953 Glycos_transf_4; PF10555 MraY_sig1 [H]

EC number: =2.7.8.13 [H]

Molecular weight: Translated: 35097; Mature: 34966

Theoretical pI: Translated: 9.99; Mature: 9.99

Prosite motif: PS01348 MRAY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSTVIYAVLFSFLLSTITSLLLIPLFKKLNLGQSIKNGIPISHKKKAGTLTFGGIIFIFS
CHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHH
SIITMLFMIKNYNKELLLIISSLIAFGLIGFIDDTLKKIHKKNEGLTSKGKMILLLFVSS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IFAIYSYYDPSIGSIIMFPFTKKLFDLRILYIPFIIFYYVSTTNALNLTDGLDGLATSIT
HHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHH
LLVVTFFTFLSFGMGHYTLSISCGCIAGALLGFLRYNCYPAKIIMGDTGSLALGGAIATI
HHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHH
AMILKNPFIVIIVGGIYVIEALSSLIQIVFFKLFSKRIFKMAPIHHSFELHGWHETKIVS
HHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHH
VFSIITTILCLIGFLSM
HHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
STVIYAVLFSFLLSTITSLLLIPLFKKLNLGQSIKNGIPISHKKKAGTLTFGGIIFIFS
HHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHCCCCCCCCCCCCCCHHHHHHHHHH
SIITMLFMIKNYNKELLLIISSLIAFGLIGFIDDTLKKIHKKNEGLTSKGKMILLLFVSS
HHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHH
IFAIYSYYDPSIGSIIMFPFTKKLFDLRILYIPFIIFYYVSTTNALNLTDGLDGLATSIT
HHHHHHHCCCCCCCEEEHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCCHHHHHHHHH
LLVVTFFTFLSFGMGHYTLSISCGCIAGALLGFLRYNCYPAKIIMGDTGSLALGGAIATI
HHHHHHHHHHHHCCCCEEEEEEHHHHHHHHHHHHHHCCEEEEEEECCCCCCHHHHHHHHH
AMILKNPFIVIIVGGIYVIEALSSLIQIVFFKLFSKRIFKMAPIHHSFELHGWHETKIVS
HHHHCCCEEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEECCCCHHHHHH
VFSIITTILCLIGFLSM
HHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA