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The map label for this gene is hicB [H]

Identifier: 170752084

GI number: 170752084

Start: 6037894

End: 6038313

Strand: Direct

Name: hicB [H]

Synonym: Mrad2831_5716

Alternate gene names: 170752084

Gene position: 6037894-6038313 (Clockwise)

Preceding gene: 170752083

Following gene: 170752096

Centisome position: 99.34

GC content: 70.0

Gene sequence:

>420_bases
ATGCTCAGATACCCCGTGGTGCTGACCCCCGATGACGACGGCAGCCTGCTGGTGACCTGCCCGGACCTGCCGGAGGTCAC
CAGCTTCGGCGACGATGAGGCCGAGGCACTCATTCACGGTGCGGACGCGGTTGCGACGGCCCTCAAGGGCCGGATCACGG
CGCGCCAGCCCATTCCGGAGCCCAGCCCGATCACCGACCGCTCGGTCGCCCTGTCGTCGCTGATCGCCCTGAAGCTCGAA
CTCTATCGGGCGATGGCCGAGACGAACGTCCGGAAGGCCGATCTCGTCCGCCGGCTCCAGGTCCACCCGCCGCAGGTCGA
CCGGCTGCTCGACCTCGACCACGATTCCCGCCTGGATCAGCTCGAGGCGGCTCTCACGGCGTGCGGCCGCGAGATCGTCG
TGGCGACCCGGGCCGCGTGA

Upstream 100 bases:

>100_bases
GCCGGATGTCGGTGCTTCCGCAGCATGGCGGCTCGAAGGAGCTGGGCACAGGGCTCTGGAAGAAGATCCTCAAGGATCTG
GAGATCAAGGAGTAGGACGG

Downstream 100 bases:

>100_bases
AGCTGCGCTCGCCGGGGCCATCAGCGAGCCTGCCGTACTCGGCCTATGACGGAGGTGAGCTCGTCGATCAGGGTTTCTCT
CTCGGTGCAAGCTGGGCATC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 139; Mature: 139

Protein sequence:

>139_residues
MLRYPVVLTPDDDGSLLVTCPDLPEVTSFGDDEAEALIHGADAVATALKGRITARQPIPEPSPITDRSVALSSLIALKLE
LYRAMAETNVRKADLVRRLQVHPPQVDRLLDLDHDSRLDQLEAALTACGREIVVATRAA

Sequences:

>Translated_139_residues
MLRYPVVLTPDDDGSLLVTCPDLPEVTSFGDDEAEALIHGADAVATALKGRITARQPIPEPSPITDRSVALSSLIALKLE
LYRAMAETNVRKADLVRRLQVHPPQVDRLLDLDHDSRLDQLEAALTACGREIVVATRAA
>Mature_139_residues
MLRYPVVLTPDDDGSLLVTCPDLPEVTSFGDDEAEALIHGADAVATALKGRITARQPIPEPSPITDRSVALSSLIALKLE
LYRAMAETNVRKADLVRRLQVHPPQVDRLLDLDHDSRLDQLEAALTACGREIVVATRAA

Specific function: Part of a toxin-antitoxin (TA) module. Functions as an mRNA interferase antitoxin preventing effects of the HicA toxin [H]

COG id: COG1598

COG function: function code S; Uncharacterized conserved protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HicB antitoxin family [H]

Homologues:

Organism=Escherichia coli, GI145693129, Length=133, Percent_Identity=31.5789473684211, Blast_Score=76, Evalue=7e-16,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012287
- InterPro:   IPR005357 [H]

Pfam domain/function: PF03681 UPF0150 [H]

EC number: NA

Molecular weight: Translated: 15088; Mature: 15088

Theoretical pI: Translated: 4.64; Mature: 4.64

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
1.4 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLRYPVVLTPDDDGSLLVTCPDLPEVTSFGDDEAEALIHGADAVATALKGRITARQPIPE
CCCCCEEEECCCCCCEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSPITDRSVALSSLIALKLELYRAMAETNVRKADLVRRLQVHPPQVDRLLDLDHDSRLDQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCCCCHHHH
LEAALTACGREIVVATRAA
HHHHHHHCCCEEEEEECCC
>Mature Secondary Structure
MLRYPVVLTPDDDGSLLVTCPDLPEVTSFGDDEAEALIHGADAVATALKGRITARQPIPE
CCCCCEEEECCCCCCEEEECCCCCCHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCC
PSPITDRSVALSSLIALKLELYRAMAETNVRKADLVRRLQVHPPQVDRLLDLDHDSRLDQ
CCCCCHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCCCHHHHCCCCCCCHHHH
LEAALTACGREIVVATRAA
HHHHHHHCCCEEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA