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The map label for this gene is yrkP [H]

Identifier: 170751882

GI number: 170751882

Start: 5830601

End: 5831518

Strand: Direct

Name: yrkP [H]

Synonym: Mrad2831_5514

Alternate gene names: 170751882

Gene position: 5830601-5831518 (Clockwise)

Preceding gene: 170751881

Following gene: 170751883

Centisome position: 95.93

GC content: 72.98

Gene sequence:

>918_bases
ATGGCTGAGGCGCCGACGGTTCAGCCGCACCGGGACATCGTCCTTGTGATCGACGATTCGCCCGACACGCTGAGCTTCCT
CACCGAGGCGATCGAGCGGTCCGGCGCCACCGTGCTGGTCGCGGTCGGCGGCGATCTCGCCCTGACCCTGGTGGACGAGA
TCACGCCGGACGTGATCCTGCTCGACGCGGTGATGCCGGGCCTCGACGGGTTCGAGACCTGCCGGCGGCTCAAGGCCAAG
CCGCAGCTCGCCGGCGTGCCGGTGATCTTCATGACCGGGCTGAGCGAGACCGAGCACATCGTGAAGGGGCTTTCCGCCGG
CGGGGTCGACTACGTCACGAAGCCCATCGCCCCGGACGAGATCCTGGCCCGGATCCGCGTGCATCTGGCGAGCGCCCGCG
CCGCGCAGAGCGCCCGGGCCGCCCTCGACACCGCCGGGAGGACGCTGTTCGCGGTCGCCGAGGACGGCACGGTCCTGTGG
TCGACGCCGCAGGCCGGGCGTCTGCTCGCCGGACTCGGCGCGGATCCGTCCGGCACCCGCGCGCTGCCCGCCGGCGCCCG
TGACTGGCTGCGTGGCTGCCTCGCCGGCGCCGCCCAGCCGCTCGCGCTGACCGATCGCGACGGCGTCGCCTACGCCCTGA
GCTTCATCGGCCGCACCCCGGACGAGATCCTGCTCCGCCTGTCGCGCGACGCGCTGTCGGCGGGGGTCGAGCGGCTGCGG
GCGCGCCTGCCGGTCACCGGGCGCGAGGCGGAGGTTCTCCTCTGGCTGTCCCGGGGCAAGTCGAGCCGCGACATCGGCGA
GATCCTCGGGCTCAGCCACCGGACCGTGACGAAGCACCTCGAGGGCATCTACGCGAAGCTCGGTGTGGAGAACCGCACGG
CCGCCTCGATCATCGCGGCGCGGCACCTGCAGGATTGA

Upstream 100 bases:

>100_bases
GATGCGACCGTGCCGCCCGCCTTCGTCGCCCGCATGCGCGGACTGGTCGAGGGGTACGACCTGCGCCGCTACCTCTCGGT
CCTGCAGGAGCTCGCCCGCC

Downstream 100 bases:

>100_bases
GCCCGCTCGCGAACCGGTCGGCAGGGTTGCGGTGGCCGCGGATCCCCAAGCTTGTCCACAGGCCTGGGTGCTCGGGGAAA
CGCCTTGGTAAGCCCCGCCG

Product: two component LuxR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 305; Mature: 304

Protein sequence:

>305_residues
MAEAPTVQPHRDIVLVIDDSPDTLSFLTEAIERSGATVLVAVGGDLALTLVDEITPDVILLDAVMPGLDGFETCRRLKAK
PQLAGVPVIFMTGLSETEHIVKGLSAGGVDYVTKPIAPDEILARIRVHLASARAAQSARAALDTAGRTLFAVAEDGTVLW
STPQAGRLLAGLGADPSGTRALPAGARDWLRGCLAGAAQPLALTDRDGVAYALSFIGRTPDEILLRLSRDALSAGVERLR
ARLPVTGREAEVLLWLSRGKSSRDIGEILGLSHRTVTKHLEGIYAKLGVENRTAASIIAARHLQD

Sequences:

>Translated_305_residues
MAEAPTVQPHRDIVLVIDDSPDTLSFLTEAIERSGATVLVAVGGDLALTLVDEITPDVILLDAVMPGLDGFETCRRLKAK
PQLAGVPVIFMTGLSETEHIVKGLSAGGVDYVTKPIAPDEILARIRVHLASARAAQSARAALDTAGRTLFAVAEDGTVLW
STPQAGRLLAGLGADPSGTRALPAGARDWLRGCLAGAAQPLALTDRDGVAYALSFIGRTPDEILLRLSRDALSAGVERLR
ARLPVTGREAEVLLWLSRGKSSRDIGEILGLSHRTVTKHLEGIYAKLGVENRTAASIIAARHLQD
>Mature_304_residues
AEAPTVQPHRDIVLVIDDSPDTLSFLTEAIERSGATVLVAVGGDLALTLVDEITPDVILLDAVMPGLDGFETCRRLKAKP
QLAGVPVIFMTGLSETEHIVKGLSAGGVDYVTKPIAPDEILARIRVHLASARAAQSARAALDTAGRTLFAVAEDGTVLWS
TPQAGRLLAGLGADPSGTRALPAGARDWLRGCLAGAAQPLALTDRDGVAYALSFIGRTPDEILLRLSRDALSAGVERLRA
RLPVTGREAEVLLWLSRGKSSRDIGEILGLSHRTVTKHLEGIYAKLGVENRTAASIIAARHLQD

Specific function: Member of the two-component regulatory system yrkQ/yrkP [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786599, Length=113, Percent_Identity=34.5132743362832, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1788394, Length=169, Percent_Identity=29.585798816568, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1788550, Length=150, Percent_Identity=30, Blast_Score=73, Evalue=3e-14,
Organism=Escherichia coli, GI1786784, Length=116, Percent_Identity=34.4827586206897, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1790860, Length=125, Percent_Identity=35.2, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082012, Length=126, Percent_Identity=33.3333333333333, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1790299, Length=130, Percent_Identity=31.5384615384615, Blast_Score=65, Evalue=5e-12,
Organism=Escherichia coli, GI1789809, Length=113, Percent_Identity=32.7433628318584, Blast_Score=64, Evalue=9e-12,
Organism=Escherichia coli, GI1786911, Length=166, Percent_Identity=32.5301204819277, Blast_Score=63, Evalue=3e-11,
Organism=Escherichia coli, GI1790437, Length=127, Percent_Identity=33.0708661417323, Blast_Score=61, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 32219; Mature: 32088

Theoretical pI: Translated: 6.26; Mature: 6.26

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50043 HTH_LUXR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.6 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAEAPTVQPHRDIVLVIDDSPDTLSFLTEAIERSGATVLVAVGGDLALTLVDEITPDVIL
CCCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCEEEEEHHHCCCCEEE
LDAVMPGLDGFETCRRLKAKPQLAGVPVIFMTGLSETEHIVKGLSAGGVDYVTKPIAPDE
EEHHCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHCCCCHHHHCCCCCHHH
ILARIRVHLASARAAQSARAALDTAGRTLFAVAEDGTVLWSTPQAGRLLAGLGADPSGTR
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCEEEECCCCCCCCC
ALPAGARDWLRGCLAGAAQPLALTDRDGVAYALSFIGRTPDEILLRLSRDALSAGVERLR
CCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ARLPVTGREAEVLLWLSRGKSSRDIGEILGLSHRTVTKHLEGIYAKLGVENRTAASIIAA
HHCCCCCCCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RHLQD
HHCCC
>Mature Secondary Structure 
AEAPTVQPHRDIVLVIDDSPDTLSFLTEAIERSGATVLVAVGGDLALTLVDEITPDVIL
CCCCCCCCCCCEEEEECCCCCHHHHHHHHHHHCCCEEEEEECCCEEEEEHHHCCCCEEE
LDAVMPGLDGFETCRRLKAKPQLAGVPVIFMTGLSETEHIVKGLSAGGVDYVTKPIAPDE
EEHHCCCCCHHHHHHHHHCCCCCCCCCEEEEECCCHHHHHHHHHCCCCHHHHCCCCCHHH
ILARIRVHLASARAAQSARAALDTAGRTLFAVAEDGTVLWSTPQAGRLLAGLGADPSGTR
HHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEECCCEEEECCCCCCCEEEECCCCCCCCC
ALPAGARDWLRGCLAGAAQPLALTDRDGVAYALSFIGRTPDEILLRLSRDALSAGVERLR
CCCCCHHHHHHHHHHCCCCCCEEECCCCHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHH
ARLPVTGREAEVLLWLSRGKSSRDIGEILGLSHRTVTKHLEGIYAKLGVENRTAASIIAA
HHCCCCCCCCEEEEEEECCCCCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHH
RHLQD
HHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969508; 9384377 [H]