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The map label for this gene is yjjL [H]

Identifier: 170751840

GI number: 170751840

Start: 5785655

End: 5786968

Strand: Direct

Name: yjjL [H]

Synonym: Mrad2831_5472

Alternate gene names: 170751840

Gene position: 5785655-5786968 (Clockwise)

Preceding gene: 170751838

Following gene: 170751845

Centisome position: 95.19

GC content: 70.78

Gene sequence:

>1314_bases
ATGGCCCTGGCCGCAACGCCGCGCGTGCGCCGCATCCAGACGATCTCGCTCGCCCTGCTCGTCACGGCGGGCGTCGTCAA
CTACGTCGACCGGGCCACCCTGGCGGTGGCCAACCCGCTGATCCGCGAGGATCTCGGCCTCTCGATCCCCGACATGGGAT
TGCTGCTCTCGGCCTTCCTCTGGGCATACGCCTTCGCGCAGCTCCCGGCCGGGGCGCTCGCCGACCGGCTCGGCCCGCGC
CTGACGCTGACGCTCGGCCTGACCTGCTGGTCGTTCGGCCAGATGCTCGGCGGCGCGGTGACGTCGTTCTGGCAGTTCGT
GAGCGCGCGGATCGTGCTCGGTGTCGGCGAGGCGCCGCATTTTCCGACCTGCGCCCGGGTCTCCCGGGACTGGTTCAACA
TCCGCCAGCGCGGCACCGCCACGGGAATCTGGAACTGCGCCTCCTCACTCGGGACCTTCCTGGCCCTGCCGCTGCTCACC
TTCCTCATGGTGAGCTTCGGCTGGCGGGCGATGTTCGTCATCATGGGCGCGGCCGGCCTCGTGCTCGCCGCGATCGTCTA
CCTGGTCTTCCGCAACCCGCGCGAGACCGACCTGACGCCGGGGGAGCGCGCCTTCCTGGAAGAGGGCGACGCCCCGAACG
CGAGCCGCGCGGTCACCTGGAGCGCGTGGCGACGGCTCTTCGGGTTCCGCACCAGCTGGGGGATGATCGTCGGCTATTTC
GGCTGCATCTACATGACGTGGCTCTACACCGCGTGGCTGCCGAGCTACCTCGAGATCGAGCGACACTTCACCCTGCAGAA
GACCGGCCTCGTCGGCTCGATCCCCTTCGCCTTCGGCGTGCTGGGCGGGATCCTGGGCGGCCGCGTCGTCGATGTCCTCG
TCCGCCGCGGCGTCGACCCGATCCGCAGCCGCAAGATCCCGATGGTCGGCTCCCTGGTGGCGACTGCCGCCTTCACGGTG
GTGGCGGCGCTGACGCCGAGCGACACCCTCGCCATCGCCTGCATCTCGGCCTCGCTGTTCCTGGTCTACATGAGCTCGTC
GTCGGCCTGGGCGATGGCCTCCGTGGCGGCGCCGGCGAGCTGCACGGCGTCGCTCGGCGCCATGCAGAATTTCGGCGGCT
ACATCGGCGGCGCCCTGGCGCCGACCGTGACGGGCTTCATCGTCGGCGGCACGGGCCACTTCTCCATGGCCTTCATCACC
GGGGCCGCGATCGCCCTGGTGGCGGCCCTGGGCTACTGGACGCTGATCCAGGATCCCATCGCCGACGAGGGACCGGAGAG
CCCGATCGTCGGCGCGCTCGGGGCCGCGCGCTAG

Upstream 100 bases:

>100_bases
CGGCGGCATTCGGTGCAGAATGGTCCCGGGCCGCCGCGAGTCGCGAAGGACCGGCCGGCCACGGAGACCCCCAAGGGGCC
CGTCATACCGGGAGGACACG

Downstream 100 bases:

>100_bases
GCGGGCCGACCGCGCTTCCTTGGCGTCAGCCCCTCGCGTCACCCCCGCAGGTTCGGCGCGGCGAGGATCAGGTCGCGGAG
GTGCGTGCGGGCCGTGAAGC

Product: major facilitator transporter

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 437; Mature: 436

Protein sequence:

>437_residues
MALAATPRVRRIQTISLALLVTAGVVNYVDRATLAVANPLIREDLGLSIPDMGLLLSAFLWAYAFAQLPAGALADRLGPR
LTLTLGLTCWSFGQMLGGAVTSFWQFVSARIVLGVGEAPHFPTCARVSRDWFNIRQRGTATGIWNCASSLGTFLALPLLT
FLMVSFGWRAMFVIMGAAGLVLAAIVYLVFRNPRETDLTPGERAFLEEGDAPNASRAVTWSAWRRLFGFRTSWGMIVGYF
GCIYMTWLYTAWLPSYLEIERHFTLQKTGLVGSIPFAFGVLGGILGGRVVDVLVRRGVDPIRSRKIPMVGSLVATAAFTV
VAALTPSDTLAIACISASLFLVYMSSSSAWAMASVAAPASCTASLGAMQNFGGYIGGALAPTVTGFIVGGTGHFSMAFIT
GAAIALVAALGYWTLIQDPIADEGPESPIVGALGAAR

Sequences:

>Translated_437_residues
MALAATPRVRRIQTISLALLVTAGVVNYVDRATLAVANPLIREDLGLSIPDMGLLLSAFLWAYAFAQLPAGALADRLGPR
LTLTLGLTCWSFGQMLGGAVTSFWQFVSARIVLGVGEAPHFPTCARVSRDWFNIRQRGTATGIWNCASSLGTFLALPLLT
FLMVSFGWRAMFVIMGAAGLVLAAIVYLVFRNPRETDLTPGERAFLEEGDAPNASRAVTWSAWRRLFGFRTSWGMIVGYF
GCIYMTWLYTAWLPSYLEIERHFTLQKTGLVGSIPFAFGVLGGILGGRVVDVLVRRGVDPIRSRKIPMVGSLVATAAFTV
VAALTPSDTLAIACISASLFLVYMSSSSAWAMASVAAPASCTASLGAMQNFGGYIGGALAPTVTGFIVGGTGHFSMAFIT
GAAIALVAALGYWTLIQDPIADEGPESPIVGALGAAR
>Mature_436_residues
ALAATPRVRRIQTISLALLVTAGVVNYVDRATLAVANPLIREDLGLSIPDMGLLLSAFLWAYAFAQLPAGALADRLGPRL
TLTLGLTCWSFGQMLGGAVTSFWQFVSARIVLGVGEAPHFPTCARVSRDWFNIRQRGTATGIWNCASSLGTFLALPLLTF
LMVSFGWRAMFVIMGAAGLVLAAIVYLVFRNPRETDLTPGERAFLEEGDAPNASRAVTWSAWRRLFGFRTSWGMIVGYFG
CIYMTWLYTAWLPSYLEIERHFTLQKTGLVGSIPFAFGVLGGILGGRVVDVLVRRGVDPIRSRKIPMVGSLVATAAFTVV
AALTPSDTLAIACISASLFLVYMSSSSAWAMASVAAPASCTASLGAMQNFGGYIGGALAPTVTGFIVGGTGHFSMAFITG
AAIALVAALGYWTLIQDPIADEGPESPIVGALGAAR

Specific function: Responsible for the transport of L-galactonate from the periplasm across the inner membrane (Probable). Is essential for growth on L-galactonate as the sole carbon source [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the major facilitator superfamily. Phthalate permease family [H]

Homologues:

Organism=Homo sapiens, GI154350196, Length=396, Percent_Identity=23.4848484848485, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI9966811, Length=396, Percent_Identity=24.7474747474747, Blast_Score=89, Evalue=7e-18,
Organism=Homo sapiens, GI9945322, Length=390, Percent_Identity=23.8461538461538, Blast_Score=81, Evalue=2e-15,
Organism=Homo sapiens, GI6912666, Length=378, Percent_Identity=23.015873015873, Blast_Score=76, Evalue=6e-14,
Organism=Homo sapiens, GI21322234, Length=395, Percent_Identity=23.7974683544304, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI4885441, Length=389, Percent_Identity=22.3650385604113, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI148743791, Length=331, Percent_Identity=22.3564954682779, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI256219598, Length=379, Percent_Identity=24.2744063324538, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4503847, Length=379, Percent_Identity=24.2744063324538, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI256219483, Length=379, Percent_Identity=24.2744063324538, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI256219543, Length=196, Percent_Identity=27.5510204081633, Blast_Score=66, Evalue=6e-11,
Organism=Escherichia coli, GI2367379, Length=415, Percent_Identity=42.8915662650602, Blast_Score=349, Evalue=2e-97,
Organism=Escherichia coli, GI87082320, Length=426, Percent_Identity=31.924882629108, Blast_Score=212, Evalue=3e-56,
Organism=Escherichia coli, GI1789515, Length=431, Percent_Identity=32.2505800464037, Blast_Score=194, Evalue=7e-51,
Organism=Escherichia coli, GI1789152, Length=425, Percent_Identity=30.8235294117647, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI2367193, Length=429, Percent_Identity=24.7086247086247, Blast_Score=108, Evalue=5e-25,
Organism=Escherichia coli, GI1788573, Length=428, Percent_Identity=25.2336448598131, Blast_Score=86, Evalue=6e-18,
Organism=Escherichia coli, GI87082310, Length=164, Percent_Identity=28.0487804878049, Blast_Score=66, Evalue=5e-12,
Organism=Caenorhabditis elegans, GI71997452, Length=307, Percent_Identity=25.0814332247557, Blast_Score=84, Evalue=2e-16,
Organism=Caenorhabditis elegans, GI25141316, Length=403, Percent_Identity=23.3250620347395, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI25141318, Length=372, Percent_Identity=22.5806451612903, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17535049, Length=421, Percent_Identity=23.2779097387173, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533556, Length=296, Percent_Identity=23.6486486486486, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI115533554, Length=296, Percent_Identity=23.6486486486486, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI86561091, Length=362, Percent_Identity=23.2044198895028, Blast_Score=73, Evalue=4e-13,
Organism=Caenorhabditis elegans, GI25141341, Length=336, Percent_Identity=23.2142857142857, Blast_Score=70, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI17561094, Length=273, Percent_Identity=26.7399267399267, Blast_Score=69, Evalue=4e-12,
Organism=Caenorhabditis elegans, GI17554962, Length=301, Percent_Identity=23.5880398671096, Blast_Score=68, Evalue=8e-12,
Organism=Caenorhabditis elegans, GI17552542, Length=281, Percent_Identity=23.8434163701068, Blast_Score=67, Evalue=1e-11,
Organism=Caenorhabditis elegans, GI193208223, Length=249, Percent_Identity=23.6947791164659, Blast_Score=66, Evalue=3e-11,
Organism=Caenorhabditis elegans, GI17563054, Length=222, Percent_Identity=22.972972972973, Blast_Score=65, Evalue=6e-11,
Organism=Caenorhabditis elegans, GI17554148, Length=283, Percent_Identity=21.9081272084806, Blast_Score=65, Evalue=8e-11,
Organism=Drosophila melanogaster, GI24648416, Length=437, Percent_Identity=24.7139588100687, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI21356189, Length=437, Percent_Identity=24.7139588100687, Blast_Score=90, Evalue=3e-18,
Organism=Drosophila melanogaster, GI24583789, Length=390, Percent_Identity=24.3589743589744, Blast_Score=88, Evalue=1e-17,
Organism=Drosophila melanogaster, GI24584153, Length=399, Percent_Identity=24.5614035087719, Blast_Score=86, Evalue=4e-17,
Organism=Drosophila melanogaster, GI19920686, Length=408, Percent_Identity=22.7941176470588, Blast_Score=82, Evalue=8e-16,
Organism=Drosophila melanogaster, GI28573299, Length=316, Percent_Identity=25.9493670886076, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI20130167, Length=444, Percent_Identity=23.1981981981982, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI20130135, Length=291, Percent_Identity=26.8041237113402, Blast_Score=70, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24655271, Length=291, Percent_Identity=26.8041237113402, Blast_Score=69, Evalue=5e-12,
Organism=Drosophila melanogaster, GI24653727, Length=423, Percent_Identity=22.2222222222222, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24656866, Length=160, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI45550478, Length=160, Percent_Identity=30, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI28573708, Length=265, Percent_Identity=23.7735849056604, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI28573707, Length=265, Percent_Identity=23.7735849056604, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI24656861, Length=160, Percent_Identity=30, Blast_Score=67, Evalue=3e-11,
Organism=Drosophila melanogaster, GI45550460, Length=316, Percent_Identity=25.3164556962025, Blast_Score=66, Evalue=6e-11,
Organism=Drosophila melanogaster, GI24641682, Length=407, Percent_Identity=21.6216216216216, Blast_Score=65, Evalue=7e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020846
- InterPro:   IPR011701
- InterPro:   IPR016196 [H]

Pfam domain/function: PF07690 MFS_1 [H]

EC number: NA

Molecular weight: Translated: 46369; Mature: 46238

Theoretical pI: Translated: 9.21; Mature: 9.21

Prosite motif: PS50850 MFS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MALAATPRVRRIQTISLALLVTAGVVNYVDRATLAVANPLIREDLGLSIPDMGLLLSAFL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
WAYAFAQLPAGALADRLGPRLTLTLGLTCWSFGQMLGGAVTSFWQFVSARIVLGVGEAPH
HHHHHHHCCHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
FPTCARVSRDWFNIRQRGTATGIWNCASSLGTFLALPLLTFLMVSFGWRAMFVIMGAAGL
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAAIVYLVFRNPRETDLTPGERAFLEEGDAPNASRAVTWSAWRRLFGFRTSWGMIVGYF
HHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCEEEHHHHHHHHCCCCHHHHHHHHH
GCIYMTWLYTAWLPSYLEIERHFTLQKTGLVGSIPFAFGVLGGILGGRVVDVLVRRGVDP
HHHHHHHHHHHHCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
IRSRKIPMVGSLVATAAFTVVAALTPSDTLAIACISASLFLVYMSSSSAWAMASVAAPAS
HHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEECCCCCHHHHHHCCCCH
CTASLGAMQNFGGYIGGALAPTVTGFIVGGTGHFSMAFITGAAIALVAALGYWTLIQDPI
HHHHHHHHHHCCHHHCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
ADEGPESPIVGALGAAR
CCCCCCCCCCCCCCCCC
>Mature Secondary Structure 
ALAATPRVRRIQTISLALLVTAGVVNYVDRATLAVANPLIREDLGLSIPDMGLLLSAFL
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHHHHHHH
WAYAFAQLPAGALADRLGPRLTLTLGLTCWSFGQMLGGAVTSFWQFVSARIVLGVGEAPH
HHHHHHHCCHHHHHHHCCCEEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHEEECCCCCC
FPTCARVSRDWFNIRQRGTATGIWNCASSLGTFLALPLLTFLMVSFGWRAMFVIMGAAGL
CCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
VLAAIVYLVFRNPRETDLTPGERAFLEEGDAPNASRAVTWSAWRRLFGFRTSWGMIVGYF
HHHHHHHHHHCCCCCCCCCCCCHHHHCCCCCCCCCCEEEHHHHHHHHCCCCHHHHHHHHH
GCIYMTWLYTAWLPSYLEIERHFTLQKTGLVGSIPFAFGVLGGILGGRVVDVLVRRGVDP
HHHHHHHHHHHHCHHHHHHHHHHEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCH
IRSRKIPMVGSLVATAAFTVVAALTPSDTLAIACISASLFLVYMSSSSAWAMASVAAPAS
HHHCCCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHEEEEECCCCCHHHHHHCCCCH
CTASLGAMQNFGGYIGGALAPTVTGFIVGGTGHFSMAFITGAAIALVAALGYWTLIQDPI
HHHHHHHHHHCCHHHCHHHHHHHHEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCC
ADEGPESPIVGALGAAR
CCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503 [H]