Click here to switch to the map view.

The map label for this gene is hss [H]

Identifier: 170751426

GI number: 170751426

Start: 5358674

End: 5360119

Strand: Reverse

Name: hss [H]

Synonym: Mrad2831_5045

Alternate gene names: 170751426

Gene position: 5360119-5358674 (Counterclockwise)

Preceding gene: 170751431

Following gene: 170751422

Centisome position: 88.19

GC content: 68.81

Gene sequence:

>1446_bases
ATGACCGATCAGCCGACCCGTCACCCGATCCATGGCCGCATCACCGGCCCCATCGTGATGATCGGCTTCGGCTCGATCGG
CCGGGGCACCCTGCCGCTCATCGAGCGCCATTTCGAGTACGACCGCGCGCGCTTCACGGTGATCGACCCGGTCGACACGC
ATCGGCCTCTCGCCGAGAAGCACGGCCTCCGGTTCGAGAAGGTCGCCCTGACGCCGGAGAACTACCGCGCCGTGCTCACG
CCGCTCCTCACCGAAGGTGGCGGCCAGGGCTTCTGCGTCAACCTGTCGGTCGATACCTCCTCGCGCGCCATCATGGAGCT
CTGCCGCGAGCTCGGCGCCCTCTACATCGACACCGTGGCCGAGCCCTGGCCGGGCTTCTACTTCGACAAGACCAAGAGCC
AGGGCGACCGCACCAACTACGCGCTCCGCGAGAACATCCTCGACGCGCGCGCGCAGAAGCCCGGCGGCACCACCGCGGTC
TCCTGCTGCGGCGCCAATCCCGGCATGGTCTCGTGGTTCGTCAAGCAGGCGCTCCTGAACATCGCCCAGGATACCGGCCT
CCAGCGGCCGGAGCCGAAGACCAAGGCCGAGTGGGCCGCCCTGATGAAGGACCTGGGCGTCAAGGGCGTCCACATCGCCG
AGCGGGACACCCAGCGCGCCAAGACCCCGAAGCCGCGGGGGGTCTTCGTCAACACGTGGTCGGTCGAGGGCTTCGTCTCC
GAGGGCAATCAGCCGGCCGAGCTCGGCTGGGGCACGCACGAGACCTGGAAGCCCGCCAACGCCCGTGAGCAGGAGAAGGG
CTCGCGCTGCGCGATCTACCTGCTGCAGCCGGGGGCCGACACGCGGGTGCGCACCTGGGTGCCGACCGCCGGCTCGCAGT
TCGGCTTCCTCGTGACCCACAACGAGGCGATCTCGATCTCCGACTACTACACGGTGCGCGAGGGCGATAAGCCGGTCTTC
CGGCCCACCTGCCACTACGCCTATCACCCGGCCGACGACGCCGTGCTGTCGCTCCACGAGATGTTCGGCAAGGCGGCCCA
GGTGCAGGAGCAGCACCACATCCTCGACGAGACCGAGATCGTCGACGGCATCGACGAGCTCGGCGTGCTCGTCTACGGCC
ACGAGAAGAACGCCTACTGGTACGGCTCGCAGCTCTCCATCGAGGAGACCCGCCGGGTCGCCCCCTACCAGAACGCCACC
GGCCTGCAGGTGACCTCGGCGGTGCTCGCCGGCATGGTCTGGGCCCTGGAGAACCCGGAGGCCGGCATCGTCGAGGCCGA
CGAGATGGACTTCCGCCGCTGCCTGGAGGTCCAGACCCCGTATCTCGGCCCGGTCGTGGGCGTGTACACGGACTGGACGC
CGCTCACCGACCGTCCGGGCCTGTTCCCGGAGGACATCGACACCAGCGATCCGTGGCAGTTCCGCAACGTGCTGGTGCAC
GGCTGA

Upstream 100 bases:

>100_bases
CGGCGCGGGCCTGTCGCCGCACTGTCACACGCGCGCCATAACCCGCCCGCGAGCCAGATGAGCGGACGCGCCCGGCGCCC
GCCAGACGAGGATGTCCCGC

Downstream 100 bases:

>100_bases
GCCTCCGCGCCGAGCAGGCGCGGGCCGCTGTCGGCGGCGCGGATGTCGGGCAAGTCCGAGATCCGCGCCGGCCTGACCGG
GTCGCCCCTGCCCCGCCGCG

Product: homospermidine synthase

Products: NA

Alternate protein names: HSS [H]

Number of amino acids: Translated: 481; Mature: 480

Protein sequence:

>481_residues
MTDQPTRHPIHGRITGPIVMIGFGSIGRGTLPLIERHFEYDRARFTVIDPVDTHRPLAEKHGLRFEKVALTPENYRAVLT
PLLTEGGGQGFCVNLSVDTSSRAIMELCRELGALYIDTVAEPWPGFYFDKTKSQGDRTNYALRENILDARAQKPGGTTAV
SCCGANPGMVSWFVKQALLNIAQDTGLQRPEPKTKAEWAALMKDLGVKGVHIAERDTQRAKTPKPRGVFVNTWSVEGFVS
EGNQPAELGWGTHETWKPANAREQEKGSRCAIYLLQPGADTRVRTWVPTAGSQFGFLVTHNEAISISDYYTVREGDKPVF
RPTCHYAYHPADDAVLSLHEMFGKAAQVQEQHHILDETEIVDGIDELGVLVYGHEKNAYWYGSQLSIEETRRVAPYQNAT
GLQVTSAVLAGMVWALENPEAGIVEADEMDFRRCLEVQTPYLGPVVGVYTDWTPLTDRPGLFPEDIDTSDPWQFRNVLVH
G

Sequences:

>Translated_481_residues
MTDQPTRHPIHGRITGPIVMIGFGSIGRGTLPLIERHFEYDRARFTVIDPVDTHRPLAEKHGLRFEKVALTPENYRAVLT
PLLTEGGGQGFCVNLSVDTSSRAIMELCRELGALYIDTVAEPWPGFYFDKTKSQGDRTNYALRENILDARAQKPGGTTAV
SCCGANPGMVSWFVKQALLNIAQDTGLQRPEPKTKAEWAALMKDLGVKGVHIAERDTQRAKTPKPRGVFVNTWSVEGFVS
EGNQPAELGWGTHETWKPANAREQEKGSRCAIYLLQPGADTRVRTWVPTAGSQFGFLVTHNEAISISDYYTVREGDKPVF
RPTCHYAYHPADDAVLSLHEMFGKAAQVQEQHHILDETEIVDGIDELGVLVYGHEKNAYWYGSQLSIEETRRVAPYQNAT
GLQVTSAVLAGMVWALENPEAGIVEADEMDFRRCLEVQTPYLGPVVGVYTDWTPLTDRPGLFPEDIDTSDPWQFRNVLVH
G
>Mature_480_residues
TDQPTRHPIHGRITGPIVMIGFGSIGRGTLPLIERHFEYDRARFTVIDPVDTHRPLAEKHGLRFEKVALTPENYRAVLTP
LLTEGGGQGFCVNLSVDTSSRAIMELCRELGALYIDTVAEPWPGFYFDKTKSQGDRTNYALRENILDARAQKPGGTTAVS
CCGANPGMVSWFVKQALLNIAQDTGLQRPEPKTKAEWAALMKDLGVKGVHIAERDTQRAKTPKPRGVFVNTWSVEGFVSE
GNQPAELGWGTHETWKPANAREQEKGSRCAIYLLQPGADTRVRTWVPTAGSQFGFLVTHNEAISISDYYTVREGDKPVFR
PTCHYAYHPADDAVLSLHEMFGKAAQVQEQHHILDETEIVDGIDELGVLVYGHEKNAYWYGSQLSIEETRRVAPYQNATG
LQVTSAVLAGMVWALENPEAGIVEADEMDFRRCLEVQTPYLGPVVGVYTDWTPLTDRPGLFPEDIDTSDPWQFRNVLVHG

Specific function: Involved in the NAD(+)-dependent synthesis of the polyamine homospermidine from putrescine [H]

COG id: COG5310

COG function: function code Q; Homospermidine synthase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: NA

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023181
- InterPro:   IPR016040
- InterPro:   IPR005097 [H]

Pfam domain/function: PF03435 Saccharop_dh [H]

EC number: =2.5.1.44 [H]

Molecular weight: Translated: 53534; Mature: 53403

Theoretical pI: Translated: 5.59; Mature: 5.59

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.5 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
3.1 %Cys+Met (Translated Protein)
1.5 %Cys     (Mature Protein)
1.5 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTDQPTRHPIHGRITGPIVMIGFGSIGRGTLPLIERHFEYDRARFTVIDPVDTHRPLAEK
CCCCCCCCCCCCEECCCEEEEECCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
HGLRFEKVALTPENYRAVLTPLLTEGGGQGFCVNLSVDTSSRAIMELCRELGALYIDTVA
CCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHCCEEEHHHC
EPWPGFYFDKTKSQGDRTNYALRENILDARAQKPGGTTAVSCCGANPGMVSWFVKQALLN
CCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
IAQDTGLQRPEPKTKAEWAALMKDLGVKGVHIAERDTQRAKTPKPRGVFVNTWSVEGFVS
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHCCCCCCCEEEEEEEEEEEHCC
EGNQPAELGWGTHETWKPANAREQEKGSRCAIYLLQPGADTRVRTWVPTAGSQFGFLVTH
CCCCCCCCCCCCCCCCCCCCCCHHCCCCEEEEEEECCCCCCEEEEEECCCCCCEEEEEEC
NEAISISDYYTVREGDKPVFRPTCHYAYHPADDAVLSLHEMFGKAAQVQEQHHILDETEI
CCEEEEECEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCHHHHHHHHHHHCCHHHH
VDGIDELGVLVYGHEKNAYWYGSQLSIEETRRVAPYQNATGLQVTSAVLAGMVWALENPE
HCCHHHCCEEEEEECCCCEEECCEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCC
AGIVEADEMDFRRCLEVQTPYLGPVVGVYTDWTPLTDRPGLFPEDIDTSDPWQFRNVLVH
CCCEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHEHHEEEC
G
C
>Mature Secondary Structure 
TDQPTRHPIHGRITGPIVMIGFGSIGRGTLPLIERHFEYDRARFTVIDPVDTHRPLAEK
CCCCCCCCCCCEECCCEEEEECCCCCCCCHHHHHHHHCCCCCEEEEECCCCCCCCHHHH
HGLRFEKVALTPENYRAVLTPLLTEGGGQGFCVNLSVDTSSRAIMELCRELGALYIDTVA
CCCEEEEEEECCCCCHHHHHHHHHCCCCCEEEEEEEECCCHHHHHHHHHHHCCEEEHHHC
EPWPGFYFDKTKSQGDRTNYALRENILDARAQKPGGTTAVSCCGANPGMVSWFVKQALLN
CCCCCCEECCCCCCCCCCHHHHHHHHHHHHCCCCCCCCEEEECCCCCCHHHHHHHHHHHH
IAQDTGLQRPEPKTKAEWAALMKDLGVKGVHIAERDTQRAKTPKPRGVFVNTWSVEGFVS
HHHHCCCCCCCCCHHHHHHHHHHHCCCCCEEEECCCHHHCCCCCCCEEEEEEEEEEEHCC
EGNQPAELGWGTHETWKPANAREQEKGSRCAIYLLQPGADTRVRTWVPTAGSQFGFLVTH
CCCCCCCCCCCCCCCCCCCCCCHHCCCCEEEEEEECCCCCCEEEEEECCCCCCEEEEEEC
NEAISISDYYTVREGDKPVFRPTCHYAYHPADDAVLSLHEMFGKAAQVQEQHHILDETEI
CCEEEEECEEEEECCCCCCCCCCCCEEECCCHHHHHHHHHHHCHHHHHHHHHHHCCHHHH
VDGIDELGVLVYGHEKNAYWYGSQLSIEETRRVAPYQNATGLQVTSAVLAGMVWALENPE
HCCHHHCCEEEEEECCCCEEECCEECHHHHHCCCCCCCCCCHHHHHHHHHHHHHEECCCC
AGIVEADEMDFRRCLEVQTPYLGPVVGVYTDWTPLTDRPGLFPEDIDTSDPWQFRNVLVH
CCCEECCHHHHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCCHHEHHEEEC
G
C

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8841401 [H]