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The map label for this gene is feaR [H]

Identifier: 170751258

GI number: 170751258

Start: 5208471

End: 5209430

Strand: Reverse

Name: feaR [H]

Synonym: Mrad2831_4875

Alternate gene names: 170751258

Gene position: 5209430-5208471 (Counterclockwise)

Preceding gene: 170751259

Following gene: 170751255

Centisome position: 85.71

GC content: 74.9

Gene sequence:

>960_bases
GTGTCTAGCCCGGAGCTCGTCCCGAGCCTCGTCGAGACGACCAGCCACGTCGACCCCAAACGGGCCTTCGAGTTCTGGCG
CTGCACGGCCCTGGCCAGGTTCGGCGATATCGGCCGGCGGCACCCCCGGGAGCGGTTCTCGGCCAAGCGCCTGAGCGTGG
CCTCGGCCGGCTGGTCGCTGACCCACACGGTGAGCAGCCCGGTCGAGCTGGAGTTCCGGTCCCGCCACGTCGACCGCAAC
GCCCGCGCCATGGTGGTGATCGGCCTCGGGCTCGACGGCGTCGGCTATCACGAGCAGCACGGACGGGGCGCCCAGCTGAA
CCCGGGCGACATCAGCTTCCTGACGCGGAACCGGCCCTTCGTGGCCGGCACCCAGAGCGCCTACGAAGAGATCCGCCTCG
CCGTCCCGCGCGAGATGTTCGAGGCCTGGATCGGCGCCGCCGACGCCTTCGCGGGCCGCAGCCTCGGCCCGCAGCCGGCC
GGGGCGGAGGTCCGGGCGCGGCTGCGCGGCGTGGCCGGCTCGATCGCCTGGATGTCCGCGGACGAGGCGCAGGCGGCCGT
CGAGGGCGTGCTCCATCTCCTCGGCCACCTCGTCGACGGCGCCGCCCGGCGCGGCGACCCGGAGGCGGTCTCGCAGGCGG
CCGTCGTCTCCCTCGCCCGCGCCCATATCGCGCGGCGGATGCACGATCCCGACCTGAACCCGCAGGACATCCAGCGCGCG
CTGGGCCTCTCCCGGACCAGCCTGTACCGCGCCTTCGCGGAGACCGGCGGCATCGCGGCGGCGATCCGCGACGCGCGCCT
CGACCTCGCGCGCCGGCGCCTCGAGGCCCGCCGCGACGACAAGGTCCGGATCGCCTCGATCGCCTACGCGTGCGGCTTCA
CCGACGTGCCGACCTTCAACCGCGGCTTCCGCAAGCGCTTCGGCCTGGCCCCGGGCGACCTCCGGCCCACGCTCCCCTAG

Upstream 100 bases:

>100_bases
GCAGGCGGGACCGGGGCGGATGGCGCCGGTTGCCGATCCGGCACGATTCACACGATAGGGTCGCGCAGGCGGCCGAAAGG
GCGCGCCGGGAGTGCCGCAC

Downstream 100 bases:

>100_bases
GCGCGGCGCGTCAGCCGGCGGCGGCGAGATCCGCCCGGCCCCGGACCTCGGCGGGGAAATCGAACACCGCGTCCGCGTGC
GCGATCGTCGCCGGGCGATG

Product: AraC family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 319; Mature: 318

Protein sequence:

>319_residues
MSSPELVPSLVETTSHVDPKRAFEFWRCTALARFGDIGRRHPRERFSAKRLSVASAGWSLTHTVSSPVELEFRSRHVDRN
ARAMVVIGLGLDGVGYHEQHGRGAQLNPGDISFLTRNRPFVAGTQSAYEEIRLAVPREMFEAWIGAADAFAGRSLGPQPA
GAEVRARLRGVAGSIAWMSADEAQAAVEGVLHLLGHLVDGAARRGDPEAVSQAAVVSLARAHIARRMHDPDLNPQDIQRA
LGLSRTSLYRAFAETGGIAAAIRDARLDLARRRLEARRDDKVRIASIAYACGFTDVPTFNRGFRKRFGLAPGDLRPTLP

Sequences:

>Translated_319_residues
MSSPELVPSLVETTSHVDPKRAFEFWRCTALARFGDIGRRHPRERFSAKRLSVASAGWSLTHTVSSPVELEFRSRHVDRN
ARAMVVIGLGLDGVGYHEQHGRGAQLNPGDISFLTRNRPFVAGTQSAYEEIRLAVPREMFEAWIGAADAFAGRSLGPQPA
GAEVRARLRGVAGSIAWMSADEAQAAVEGVLHLLGHLVDGAARRGDPEAVSQAAVVSLARAHIARRMHDPDLNPQDIQRA
LGLSRTSLYRAFAETGGIAAAIRDARLDLARRRLEARRDDKVRIASIAYACGFTDVPTFNRGFRKRFGLAPGDLRPTLP
>Mature_318_residues
SSPELVPSLVETTSHVDPKRAFEFWRCTALARFGDIGRRHPRERFSAKRLSVASAGWSLTHTVSSPVELEFRSRHVDRNA
RAMVVIGLGLDGVGYHEQHGRGAQLNPGDISFLTRNRPFVAGTQSAYEEIRLAVPREMFEAWIGAADAFAGRSLGPQPAG
AEVRARLRGVAGSIAWMSADEAQAAVEGVLHLLGHLVDGAARRGDPEAVSQAAVVSLARAHIARRMHDPDLNPQDIQRAL
GLSRTSLYRAFAETGGIAAAIRDARLDLARRRLEARRDDKVRIASIAYACGFTDVPTFNRGFRKRFGLAPGDLRPTLP

Specific function: Positive regulator of tynA/maoA and feaB/padA, the genes for 2-phenylethylamine catabolism [H]

COG id: COG2207

COG function: function code K; AraC-type DNA-binding domain-containing proteins

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH araC/xylS-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787649, Length=294, Percent_Identity=26.1904761904762, Blast_Score=91, Evalue=1e-19,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009057
- InterPro:   IPR012287
- InterPro:   IPR020449
- InterPro:   IPR018060 [H]

Pfam domain/function: PF00165 HTH_AraC [H]

EC number: NA

Molecular weight: Translated: 34827; Mature: 34696

Theoretical pI: Translated: 10.96; Mature: 10.96

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS01124 HTH_ARAC_FAMILY_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
2.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSSPELVPSLVETTSHVDPKRAFEFWRCTALARFGDIGRRHPRERFSAKRLSVASAGWSL
CCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEE
THTVSSPVELEFRSRHVDRNARAMVVIGLGLDGVGYHEQHGRGAQLNPGDISFLTRNRPF
EECCCCCEEEHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
VAGTQSAYEEIRLAVPREMFEAWIGAADAFAGRSLGPQPAGAEVRARLRGVAGSIAWMSA
EECCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DEAQAAVEGVLHLLGHLVDGAARRGDPEAVSQAAVVSLARAHIARRMHDPDLNPQDIQRA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LGLSRTSLYRAFAETGGIAAAIRDARLDLARRRLEARRDDKVRIASIAYACGFTDVPTFN
HCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCH
RGFRKRFGLAPGDLRPTLP
HHHHHHHCCCCCCCCCCCC
>Mature Secondary Structure 
SSPELVPSLVETTSHVDPKRAFEFWRCTALARFGDIGRRHPRERFSAKRLSVASAGWSL
CCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCEE
THTVSSPVELEFRSRHVDRNARAMVVIGLGLDGVGYHEQHGRGAQLNPGDISFLTRNRPF
EECCCCCEEEHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEEEECCCCC
VAGTQSAYEEIRLAVPREMFEAWIGAADAFAGRSLGPQPAGAEVRARLRGVAGSIAWMSA
EECCHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCC
DEAQAAVEGVLHLLGHLVDGAARRGDPEAVSQAAVVSLARAHIARRMHDPDLNPQDIQRA
HHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHH
LGLSRTSLYRAFAETGGIAAAIRDARLDLARRRLEARRDDKVRIASIAYACGFTDVPTFN
HCCHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCCEEEHHHHHHCCCCCCCCCH
RGFRKRFGLAPGDLRPTLP
HHHHHHHCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8631685; 9043126; 9278503; 9109378 [H]