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The map label for this gene is yajO [H]

Identifier: 170751239

GI number: 170751239

Start: 5184640

End: 5185671

Strand: Reverse

Name: yajO [H]

Synonym: Mrad2831_4856

Alternate gene names: 170751239

Gene position: 5185671-5184640 (Counterclockwise)

Preceding gene: 170751240

Following gene: 170751238

Centisome position: 85.32

GC content: 69.77

Gene sequence:

>1032_bases
ATGGACTACAGGCAGTTCGGACGCTCCGGCCTCACCGTGCCGGTGCTCAGCTTCGGCACCGGCACCTTCGGCGGCACGAA
CGAATTCTTCCAGCGCTGGGGGCAGACGGACGTCGCCGAGGCGACCCGCATGGTCGATCTCTGCCTCGATTCCGGGGTCA
ACTTCTTCGACACGGCCGACATCTACTCCGGCGGCGCCTCGGAGGAGATCCTGGGCCAGGCCCTGAAGGGCAAGCGCGGC
CGGGCACTGATCTCCACCAAGGCGACCTTCCGGTTCAACGACGACCTGAACCAGGTCGGCTCCTCGCGCTACCACCTGAT
CCGCGCCTGCGAGGCCAGCCTGAAGCGGCTCGGCACCGACCATATCGACGTCTACTTCATGCACGGCTTCGACGCGCTCA
CGCCCGTGGACGAGACGCTGCGGGCGCTGGACGACCTCACCCGCGCGGGCAAGATCGGCTATATCGGCGCCTCGAACTTC
TCGGGCTGGCAGCTCATGAAGGCGCTCGCCACGTCCGAGCGCCACGGGCTCGCCCGCTACGTCGCCTACCAGGGCTACTA
CTCGCTGATCGGCCGGCACTACGAGTGGGAGCTGATGCCGCTCGGCCTCGACCAGGGCGTCGGCCTGATGGTCTGGAGCC
CCCTGGGCTGGGGCCGCCTCACCGGCAAGATCCGCCGCGGACAGGCCAACCAGAGCGGTCGCATCGCCGCCGGCGGCGCC
GAGGGCGGGCCGCCCGTCTCCGACGACTACCTGTTCGGCGTGGTCGACGCCCTCGACGCCGTGGCGGCCGAGACCGGCAA
GACGGTGGCGCAGGTGGCGCTCAACTGGCTGCTGACCCGGCCGACCGTCTGCAACATCGTGGTCGGCGCCCGCAACGAGG
AGCAGCTGAAGCAGAACCTCGGCGCCCTGGGCTGGACCCTGACGGCCGAGCAGGTCGCCCGCCTCGACGCGGCGAGCCAG
GAGACGCCGATCTACCCGTACTGGCACCAGCGCGGCTTCGACGAGCGCAACCCCAAGCCGACTCCCTGGTAG

Upstream 100 bases:

>100_bases
CCCGCGTCGGGCCGCACCGTCCGGGAAAGCCGGGGCGTCTCGCCGCGTTAGACCGGCAGGCGCGCCGACGCGCGGCGCCC
GCGATCGCGACGAGGATCCG

Downstream 100 bases:

>100_bases
ACCGCCGCCTCGGCCGGGACGATCAGGCGTCGCTCGGAAACGATGCGTTTCGATCGTTTCTGTTTCAACTCACTCGGTCC
CGGTCCAGGATGCCTGCGGA

Product: aldo/keto reductase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 343; Mature: 343

Protein sequence:

>343_residues
MDYRQFGRSGLTVPVLSFGTGTFGGTNEFFQRWGQTDVAEATRMVDLCLDSGVNFFDTADIYSGGASEEILGQALKGKRG
RALISTKATFRFNDDLNQVGSSRYHLIRACEASLKRLGTDHIDVYFMHGFDALTPVDETLRALDDLTRAGKIGYIGASNF
SGWQLMKALATSERHGLARYVAYQGYYSLIGRHYEWELMPLGLDQGVGLMVWSPLGWGRLTGKIRRGQANQSGRIAAGGA
EGGPPVSDDYLFGVVDALDAVAAETGKTVAQVALNWLLTRPTVCNIVVGARNEEQLKQNLGALGWTLTAEQVARLDAASQ
ETPIYPYWHQRGFDERNPKPTPW

Sequences:

>Translated_343_residues
MDYRQFGRSGLTVPVLSFGTGTFGGTNEFFQRWGQTDVAEATRMVDLCLDSGVNFFDTADIYSGGASEEILGQALKGKRG
RALISTKATFRFNDDLNQVGSSRYHLIRACEASLKRLGTDHIDVYFMHGFDALTPVDETLRALDDLTRAGKIGYIGASNF
SGWQLMKALATSERHGLARYVAYQGYYSLIGRHYEWELMPLGLDQGVGLMVWSPLGWGRLTGKIRRGQANQSGRIAAGGA
EGGPPVSDDYLFGVVDALDAVAAETGKTVAQVALNWLLTRPTVCNIVVGARNEEQLKQNLGALGWTLTAEQVARLDAASQ
ETPIYPYWHQRGFDERNPKPTPW
>Mature_343_residues
MDYRQFGRSGLTVPVLSFGTGTFGGTNEFFQRWGQTDVAEATRMVDLCLDSGVNFFDTADIYSGGASEEILGQALKGKRG
RALISTKATFRFNDDLNQVGSSRYHLIRACEASLKRLGTDHIDVYFMHGFDALTPVDETLRALDDLTRAGKIGYIGASNF
SGWQLMKALATSERHGLARYVAYQGYYSLIGRHYEWELMPLGLDQGVGLMVWSPLGWGRLTGKIRRGQANQSGRIAAGGA
EGGPPVSDDYLFGVVDALDAVAAETGKTVAQVALNWLLTRPTVCNIVVGARNEEQLKQNLGALGWTLTAEQVARLDAASQ
ETPIYPYWHQRGFDERNPKPTPW

Specific function: Unknown

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the aldo/keto reductase 2 family [H]

Homologues:

Organism=Homo sapiens, GI27436969, Length=314, Percent_Identity=33.1210191082803, Blast_Score=151, Evalue=9e-37,
Organism=Homo sapiens, GI4504825, Length=312, Percent_Identity=33.0128205128205, Blast_Score=150, Evalue=2e-36,
Organism=Homo sapiens, GI27436964, Length=333, Percent_Identity=32.1321321321321, Blast_Score=145, Evalue=4e-35,
Organism=Homo sapiens, GI27436962, Length=333, Percent_Identity=32.1321321321321, Blast_Score=145, Evalue=6e-35,
Organism=Homo sapiens, GI27436966, Length=333, Percent_Identity=31.8318318318318, Blast_Score=143, Evalue=2e-34,
Organism=Homo sapiens, GI27436971, Length=327, Percent_Identity=31.8042813455657, Blast_Score=126, Evalue=2e-29,
Organism=Homo sapiens, GI41152114, Length=301, Percent_Identity=30.2325581395349, Blast_Score=102, Evalue=4e-22,
Organism=Homo sapiens, GI223718702, Length=301, Percent_Identity=29.5681063122924, Blast_Score=102, Evalue=6e-22,
Organism=Homo sapiens, GI41327764, Length=273, Percent_Identity=30.4029304029304, Blast_Score=94, Evalue=1e-19,
Organism=Homo sapiens, GI223718708, Length=166, Percent_Identity=33.1325301204819, Blast_Score=73, Evalue=4e-13,
Organism=Escherichia coli, GI87081735, Length=333, Percent_Identity=38.7387387387387, Blast_Score=211, Evalue=4e-56,
Organism=Escherichia coli, GI1789375, Length=327, Percent_Identity=29.9694189602446, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1789199, Length=357, Percent_Identity=30.812324929972, Blast_Score=126, Evalue=3e-30,
Organism=Escherichia coli, GI1788070, Length=330, Percent_Identity=30.3030303030303, Blast_Score=119, Evalue=2e-28,
Organism=Escherichia coli, GI1788081, Length=312, Percent_Identity=27.5641025641026, Blast_Score=88, Evalue=8e-19,
Organism=Escherichia coli, GI48994888, Length=283, Percent_Identity=30.0353356890459, Blast_Score=85, Evalue=6e-18,
Organism=Escherichia coli, GI1787674, Length=282, Percent_Identity=26.241134751773, Blast_Score=69, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI212645785, Length=313, Percent_Identity=24.9201277955272, Blast_Score=70, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6325169, Length=349, Percent_Identity=28.9398280802292, Blast_Score=152, Evalue=9e-38,
Organism=Saccharomyces cerevisiae, GI6319958, Length=297, Percent_Identity=27.6094276094276, Blast_Score=124, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6323998, Length=322, Percent_Identity=27.0186335403727, Blast_Score=123, Evalue=3e-29,
Organism=Saccharomyces cerevisiae, GI6322615, Length=250, Percent_Identity=28, Blast_Score=105, Evalue=1e-23,
Organism=Saccharomyces cerevisiae, GI6319951, Length=322, Percent_Identity=24.5341614906832, Blast_Score=105, Evalue=1e-23,
Organism=Drosophila melanogaster, GI24640980, Length=348, Percent_Identity=26.1494252873563, Blast_Score=96, Evalue=4e-20,
Organism=Drosophila melanogaster, GI45549126, Length=348, Percent_Identity=26.1494252873563, Blast_Score=94, Evalue=1e-19,
Organism=Drosophila melanogaster, GI24646155, Length=323, Percent_Identity=27.2445820433437, Blast_Score=88, Evalue=7e-18,
Organism=Drosophila melanogaster, GI24646159, Length=170, Percent_Identity=35.8823529411765, Blast_Score=79, Evalue=6e-15,
Organism=Drosophila melanogaster, GI24644950, Length=361, Percent_Identity=24.9307479224377, Blast_Score=78, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001395
- InterPro:   IPR020471
- InterPro:   IPR023210 [H]

Pfam domain/function: PF00248 Aldo_ket_red [H]

EC number: 1.-.-.- [C]

Molecular weight: Translated: 37670; Mature: 37670

Theoretical pI: Translated: 6.52; Mature: 6.52

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDYRQFGRSGLTVPVLSFGTGTFGGTNEFFQRWGQTDVAEATRMVDLCLDSGVNFFDTAD
CCHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEECHH
IYSGGASEEILGQALKGKRGRALISTKATFRFNDDLNQVGSSRYHLIRACEASLKRLGTD
HHCCCCCHHHHHHHHCCCCCCEEEEECEEEEECCCHHHHCCHHHHHHHHHHHHHHHCCCC
HIDVYFMHGFDALTPVDETLRALDDLTRAGKIGYIGASNFSGWQLMKALATSERHGLARY
CEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VAYQGYYSLIGRHYEWELMPLGLDQGVGLMVWSPLGWGRLTGKIRRGQANQSGRIAAGGA
HHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCCCCCHHHCHHCCCCCCCCCCEEECCC
EGGPPVSDDYLFGVVDALDAVAAETGKTVAQVALNWLLTRPTVCNIVVGARNEEQLKQNL
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
GALGWTLTAEQVARLDAASQETPIYPYWHQRGFDERNPKPTPW
CCCCEEECHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCC
>Mature Secondary Structure
MDYRQFGRSGLTVPVLSFGTGTFGGTNEFFQRWGQTDVAEATRMVDLCLDSGVNFFDTAD
CCHHHHCCCCCEEEEEECCCCCCCCCHHHHHHCCCCHHHHHHHHHHHHHHCCCCCEECHH
IYSGGASEEILGQALKGKRGRALISTKATFRFNDDLNQVGSSRYHLIRACEASLKRLGTD
HHCCCCCHHHHHHHHCCCCCCEEEEECEEEEECCCHHHHCCHHHHHHHHHHHHHHHCCCC
HIDVYFMHGFDALTPVDETLRALDDLTRAGKIGYIGASNFSGWQLMKALATSERHGLARY
CEEEEEEECCCCCCCHHHHHHHHHHHHHCCCEEEEECCCCCHHHHHHHHHHHHHHHHHHH
VAYQGYYSLIGRHYEWELMPLGLDQGVGLMVWSPLGWGRLTGKIRRGQANQSGRIAAGGA
HHHHHHHHHHCCCCEEEEEEECCCCCCCEEEECCCCCCHHHCHHCCCCCCCCCCEEECCC
EGGPPVSDDYLFGVVDALDAVAAETGKTVAQVALNWLLTRPTVCNIVVGARNEEQLKQNL
CCCCCCCCCHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCEEEEEECCCCHHHHHHHH
GALGWTLTAEQVARLDAASQETPIYPYWHQRGFDERNPKPTPW
CCCCEEECHHHHHHHHCCCCCCCCCCCHHHCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]