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The map label for this gene is lpxB [H]

Identifier: 170748580

GI number: 170748580

Start: 2304382

End: 2304714

Strand: Reverse

Name: lpxB [H]

Synonym: Mrad2831_2162

Alternate gene names: 170748580

Gene position: 2304714-2304382 (Counterclockwise)

Preceding gene: 170748581

Following gene: 170748579

Centisome position: 37.92

GC content: 66.37

Gene sequence:

>333_bases
ATGCTGATCCAGCTCGCCCACGATCTGCCGGCCTATTTCTACGACGTGTTCGTCACCCGGCTCGACTTCTGGCTGGTGTT
CGGCATCGTCGCGCAGGTGGTGTTCGGCTCGCGCTTCATCCTGCAATGGATCGCCAGCGAGCGGGCCGGGCGGAGCGTGA
TGCCGCTGTCGTTCTGGTTCCTGTCGATCCTCGGCGGGATGATGACGCTGGTCTACGGGTTCGTCCGCCGCGAGCCGGTG
ATCATCATCGGCCAGGGCCTCTCCACCGGCATCTACCTGCGCAACCTCGCGCTGATCTTCCGCGAGCGGCGGCGGAAGCG
GGGCGCCGCGTGA

Upstream 100 bases:

>100_bases
ATCTCGCCGGCGTCTGGTGGCTGATCCGGCGCAAGCGCGCGGATCCGCGGCCCGAGGAGATCGCCGGCCCGGCCGGCCAA
ACCGCGGACCAGGACGTCGG

Downstream 100 bases:

>100_bases
GCCGCACGCCGCTGCCCGCCTTCTACGACGACCTGGACGCCACCTTCGCCGAACTGTGGCGCCTGCTGGCGGACGGCGCC
GCCCATGGCCGGAGCGGTTT

Product: lipid A biosynthesis domain-containing protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 110; Mature: 110

Protein sequence:

>110_residues
MLIQLAHDLPAYFYDVFVTRLDFWLVFGIVAQVVFGSRFILQWIASERAGRSVMPLSFWFLSILGGMMTLVYGFVRREPV
IIIGQGLSTGIYLRNLALIFRERRRKRGAA

Sequences:

>Translated_110_residues
MLIQLAHDLPAYFYDVFVTRLDFWLVFGIVAQVVFGSRFILQWIASERAGRSVMPLSFWFLSILGGMMTLVYGFVRREPV
IIIGQGLSTGIYLRNLALIFRERRRKRGAA
>Mature_110_residues
MLIQLAHDLPAYFYDVFVTRLDFWLVFGIVAQVVFGSRFILQWIASERAGRSVMPLSFWFLSILGGMMTLVYGFVRREPV
IIIGQGLSTGIYLRNLALIFRERRRKRGAA

Specific function: Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell [H]

COG id: COG3952

COG function: function code S; Predicted membrane protein

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: In the C-terminal section; belongs to the lpxB family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003835
- InterPro:   IPR011499
- ProDom:   PD339292 [H]

Pfam domain/function: PF07578 LAB_N; PF02684 LpxB [H]

EC number: =2.4.1.182 [H]

Molecular weight: Translated: 12688; Mature: 12688

Theoretical pI: Translated: 11.57; Mature: 11.57

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.6 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLIQLAHDLPAYFYDVFVTRLDFWLVFGIVAQVVFGSRFILQWIASERAGRSVMPLSFWF
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LSILGGMMTLVYGFVRREPVIIIGQGLSTGIYLRNLALIFRERRRKRGAA
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MLIQLAHDLPAYFYDVFVTRLDFWLVFGIVAQVVFGSRFILQWIASERAGRSVMPLSFWF
CEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHH
LSILGGMMTLVYGFVRREPVIIIGQGLSTGIYLRNLALIFRERRRKRGAA
HHHHHHHHHHHHHHHHCCCEEEEECCCCHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA