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The map label for this gene is yfjR [H]

Identifier: 170748573

GI number: 170748573

Start: 2297135

End: 2298004

Strand: Reverse

Name: yfjR [H]

Synonym: Mrad2831_2155

Alternate gene names: 170748573

Gene position: 2298004-2297135 (Counterclockwise)

Preceding gene: 170748575

Following gene: 170748572

Centisome position: 37.81

GC content: 73.22

Gene sequence:

>870_bases
ATGGACGTCGGATTCATCGGAATGGGGCGGATGGGTCGCGCCATGGCGGCCAACCTCGCGCGGGCCGGCCACACGGTCCG
CGCCTGGAACCGCTCGCCGGAGGCCGCGCGCGGCCTCGACGGCGTCACCCCGGTGGCGAGCGCCGCCGAGGCCTTCGCGG
GGGACGCCGTGGTCACCATGCTGGCCGACGACGCGGCCCTCGAGACCGTGATCGTCGCCGGCGGCCTCCTCGACCAGCCT
GAGCGGCCCGGCCTGCATATCGGGATGAGCACGATCTCGGTGGCCCTGGCGAAGCAGCTCGCCGCCGTGCACGCGCGGGC
GGGCGTTCCCTACATCTCGGCGCCGGTCTTCGGGCGGCCGGACGTGGCAGAGGCCGGCAAGCTCAACATCGTGGCGGCCG
GGGCGGCGGCTCTGATCGACCGCGCGGGGCCGCTCCTCGACGCCATGGGCGCCAAGACCTGGCGCTTCGGCGACGACCCG
ACGCGGGCCAATGCCGTCAAGCTCGCCGGCAACTTCATGCTGATCTCGGCCATCGAGGCCATGGCCGAGGCCTGCGCCCT
CACGGAGGGCCACGGGGTCGCGGGCGCCGACTTCCTGGACCTGATGACCAACACGCTGTTCGCCTCGCCGGTCTACAAGG
GCTACGGCGCCTCGATCGCGCAGAACCGCTACGAGCCGCCGGGCTTCATCCTCAAGCTCGGGGCCAAGGACGTGCGGCTC
GCCCTCCAGGCGGCCGAGGGTGCCGGGGTGCCGATGCCGTTCGCGAGCGTGCTGCGGGACGGTCTCATCGAGGCGATCAG
CCACGGCGACGGCGAGAAGGACCTCGCGGCGCTGGCCCGCGTCTCTGCCCGTCGTGCAGGGCAGGGTTGA

Upstream 100 bases:

>100_bases
TTGCCACGGCGGCCCATCGGCGCAAATCCGGCCGGGGCCGTTGACCGCCGGCCGGGGTTACCCAGGTTGGCAGACGGCGA
AGCGCGTCGAGGAGCACGGC

Downstream 100 bases:

>100_bases
GATCGACGACGACGTCTCGCCTTTCTGGCGAGTCTTAACCCGTCGTTTCAACTTCACAAACGAGTGTTCGTGCCGGCTAT
AGGCACGGATACCAATAGAT

Product: NAD-binding 6-phosphogluconate dehydrogenase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 289; Mature: 289

Protein sequence:

>289_residues
MDVGFIGMGRMGRAMAANLARAGHTVRAWNRSPEAARGLDGVTPVASAAEAFAGDAVVTMLADDAALETVIVAGGLLDQP
ERPGLHIGMSTISVALAKQLAAVHARAGVPYISAPVFGRPDVAEAGKLNIVAAGAAALIDRAGPLLDAMGAKTWRFGDDP
TRANAVKLAGNFMLISAIEAMAEACALTEGHGVAGADFLDLMTNTLFASPVYKGYGASIAQNRYEPPGFILKLGAKDVRL
ALQAAEGAGVPMPFASVLRDGLIEAISHGDGEKDLAALARVSARRAGQG

Sequences:

>Translated_289_residues
MDVGFIGMGRMGRAMAANLARAGHTVRAWNRSPEAARGLDGVTPVASAAEAFAGDAVVTMLADDAALETVIVAGGLLDQP
ERPGLHIGMSTISVALAKQLAAVHARAGVPYISAPVFGRPDVAEAGKLNIVAAGAAALIDRAGPLLDAMGAKTWRFGDDP
TRANAVKLAGNFMLISAIEAMAEACALTEGHGVAGADFLDLMTNTLFASPVYKGYGASIAQNRYEPPGFILKLGAKDVRL
ALQAAEGAGVPMPFASVLRDGLIEAISHGDGEKDLAALARVSARRAGQG
>Mature_289_residues
MDVGFIGMGRMGRAMAANLARAGHTVRAWNRSPEAARGLDGVTPVASAAEAFAGDAVVTMLADDAALETVIVAGGLLDQP
ERPGLHIGMSTISVALAKQLAAVHARAGVPYISAPVFGRPDVAEAGKLNIVAAGAAALIDRAGPLLDAMGAKTWRFGDDP
TRANAVKLAGNFMLISAIEAMAEACALTEGHGVAGADFLDLMTNTLFASPVYKGYGASIAQNRYEPPGFILKLGAKDVRL
ALQAAEGAGVPMPFASVLRDGLIEAISHGDGEKDLAALARVSARRAGQG

Specific function: Unknown

COG id: COG2084

COG function: function code I; 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-hydroxyisobutyrate dehydrogenase family [H]

Homologues:

Organism=Homo sapiens, GI40556376, Length=284, Percent_Identity=28.169014084507, Blast_Score=98, Evalue=7e-21,
Organism=Homo sapiens, GI23308751, Length=287, Percent_Identity=28.9198606271777, Blast_Score=79, Evalue=3e-15,
Organism=Escherichia coli, GI1790315, Length=293, Percent_Identity=32.0819112627986, Blast_Score=102, Evalue=3e-23,
Organism=Escherichia coli, GI145693186, Length=283, Percent_Identity=29.6819787985866, Blast_Score=92, Evalue=3e-20,
Organism=Escherichia coli, GI1786719, Length=283, Percent_Identity=28.2685512367491, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1789092, Length=284, Percent_Identity=26.7605633802817, Blast_Score=73, Evalue=2e-14,
Organism=Drosophila melanogaster, GI24655230, Length=289, Percent_Identity=30.1038062283737, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI19922568, Length=289, Percent_Identity=30.1038062283737, Blast_Score=92, Evalue=3e-19,
Organism=Drosophila melanogaster, GI28574115, Length=286, Percent_Identity=24.1258741258741, Blast_Score=72, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR015815
- InterPro:   IPR008927
- InterPro:   IPR006115
- InterPro:   IPR013328
- InterPro:   IPR016040 [H]

Pfam domain/function: PF03446 NAD_binding_2 [H]

EC number: 1.1.-.- [C]

Molecular weight: Translated: 29523; Mature: 29523

Theoretical pI: Translated: 6.36; Mature: 6.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
3.8 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
3.8 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDVGFIGMGRMGRAMAANLARAGHTVRAWNRSPEAARGLDGVTPVASAAEAFAGDAVVTM
CCCCEECCCCHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEE
LADDAALETVIVAGGLLDQPERPGLHIGMSTISVALAKQLAAVHARAGVPYISAPVFGRP
HHCHHHHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
DVAEAGKLNIVAAGAAALIDRAGPLLDAMGAKTWRFGDDPTRANAVKLAGNFMLISAIEA
CCCCCCCEEEEECHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
MAEACALTEGHGVAGADFLDLMTNTLFASPVYKGYGASIAQNRYEPPGFILKLGAKDVRL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHCCCCCHHHHCCCCCCCEEEEECCHHHHH
ALQAAEGAGVPMPFASVLRDGLIEAISHGDGEKDLAALARVSARRAGQG
HEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MDVGFIGMGRMGRAMAANLARAGHTVRAWNRSPEAARGLDGVTPVASAAEAFAGDAVVTM
CCCCEECCCCHHHHHHHHHHHCCCEEEECCCCCHHHHCCCCCCHHHHHHHHHCCCCEEEE
LADDAALETVIVAGGLLDQPERPGLHIGMSTISVALAKQLAAVHARAGVPYISAPVFGRP
HHCHHHHHHHHHCCCCCCCCCCCCEEECHHHHHHHHHHHHHHHHHHCCCCEECCCCCCCC
DVAEAGKLNIVAAGAAALIDRAGPLLDAMGAKTWRFGDDPTRANAVKLAGNFMLISAIEA
CCCCCCCEEEEECHHHHHHHHCCHHHHHHCCCCCCCCCCCCCCCEEEECCCCHHHHHHHH
MAEACALTEGHGVAGADFLDLMTNTLFASPVYKGYGASIAQNRYEPPGFILKLGAKDVRL
HHHHHHHCCCCCCCCHHHHHHHHHHHHHCCHHCCCCCHHHHCCCCCCCEEEEECCHHHHH
ALQAAEGAGVPMPFASVLRDGLIEAISHGDGEKDLAALARVSARRAGQG
HEECCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8969503; 9384377 [H]