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The map label for this gene is mcpA [H]

Identifier: 170748572

GI number: 170748572

Start: 2295318

End: 2297036

Strand: Reverse

Name: mcpA [H]

Synonym: Mrad2831_2154

Alternate gene names: 170748572

Gene position: 2297036-2295318 (Counterclockwise)

Preceding gene: 170748573

Following gene: 170748570

Centisome position: 37.79

GC content: 74.81

Gene sequence:

>1719_bases
ATGCGCACACATTCCTATTCGCTGCGCAGGATGACTCTGTCTACGAAAGTCATCCTGCTGGCGATGCTCGCCGTGACAGT
CACCGCCGGCGCCATCTGGATCACGGTCTCGCGGCAGACCTGGTCGCAGATGGAGGCGCGTCAGCGCACCAACGGCGAGC
GCAACCTGAGAACTCTGGCGCTCGTCCTGGCGGCGCGGGTCGAGGGTGCGGCGGCGGACCTCGACGGCGCGCGCGTCGCC
CGGGTGTCGACGCCGAGCCTGTCCGGCTTCGCCGATGCCGGCGTCGTGGACGACGCCGTCGCCTATTCGGGCGGCCTGGC
GACGGTGTTCAGCTACGAGCCCGCCTCCGACAGCTTCGTGCGGCGCCAGACCACGGTGCGCCGGGAGGACGGGACCCGCG
CGGTCGGCACGGCGCTCGCCGCCGACAGCCCGGCCCAGGCCGCGATCCGCGCCGGTCGGACCTACGAGGGGCCGGCCGCC
CTGTTCGGGCGGCGCTACTACACAGTGTACCACCCGACGGTCGACACCACCGGCAAGGTGAACGGCATCCTGTTCGTCGG
GCTGCCGATCGAGATGTACTTCGACGCCCACGCCCAGACGATGACGAGCCTCAGCGTCGCCGCCCTGGTCATCGCGGTGC
TGGCCTGCGCCCTCGTCGGGCTGGCGGCGGCGCGGCTGTTCCGGCCCTTCGCGACGATCGCGGCGCGGATCGAGGCCCTC
GCGGCCGGCGACTTGGACTCGGCGATCCCCCACGCGGGGCGCGGCGACGAGATCGGCACCGTGGCGCGCGCCCTCGAGGT
GCTGCGCGTCGCCGGGCTGCGGACCCGGGAGCTCGAGAGCCTGCAGAGCGCGGGCGCGGCCGACGAGACGCGGCGGCGGG
CCGCCCTCGACCGGGCCATCGAGGCGTTCCGGGGGCAGGTCGTTCGCCTGAAGGACGCGCTGACCGCCAGCACCGGCGCG
ATGCGGGCCCGGGCCGGCGAGATGGCGGCCAGCTCCGCCGAGGCGGAGGTCGCCGTCGCCGAGACCGAGCGCGGCTCGCA
CGAGACCTCGGCCAGCGTCCAGACCGTGGCGAGCGCCGCCGAGGAGCTCTCCGCCTCGATCGCCGAGATCGGGACCCAGC
TCGACCAGGCCGAGGCCCTGGTGGCCACCACCGCCGCGGAGTCGGACGCGATGAACGCCGAGATCGGCGAACTCGCCGAG
GCCGCCGGGCGCATCGGCGCCGTGGTCGGGCTGATCCGCCAGATCGCCGAGCAGACCAATCTGCTGGCGCTCAACGCCAC
GATCGAGTCCGCCCGGGCCGGCGCCGCCGGCAAGGGCTTCGCCGTGGTGGCCGCGGAGGTGAAGGCCCTGGCGTCGCAGA
CCGCGAAGGCCACCGAGGAGATCGGCAGCCAGATCGCCGGCGTGCAGGCCTCGACGACGGCGGCCGTGGCGGCGATCGGC
CGGATGGGCGAGCGGATGCGGGCGGTCAGCGCCACCACGGGCGGGATCGCGTCGGCGGTCTCGGCCCAGGGCGCGGCCAC
GGCCGAGATCTCCCGCAACGTCGCCGACACGGCCGGCGCCACCGAGGCCATCGCGGGGGGCCTCACTACGGTCGCCGGCG
CGGCCCGGCGCTCGGCCCGCATGGCCGCCACCGTCACCGACGCGGCTCAGACCGTCGACACGGTCGCGGCCGACCTCGAG
GCCGAGATCGAGCGCTTCCTCGGCCAGGTCGCGGCCTGA

Upstream 100 bases:

>100_bases
GAGATCGACGACGACGTCTCGCCTTTCTGGCGAGTCTTAACCCGTCGTTTCAACTTCACAAACGAGTGTTCGTGCCGGCT
ATAGGCACGGATACCAATAG

Downstream 100 bases:

>100_bases
CGCCTCAGAGCCCGTAGCGGGCGAAGGCCGCGCGCTCCGCGAACGCGGCCATCGCCCCCTCGGCCAGGTCGATCCCGCCC
GGCGCGCCGCCGCGGCGCAG

Product: methyl-accepting chemotaxis sensory transducer

Products: NA

Alternate protein names: Methyl-accepting chemotaxis protein [H]

Number of amino acids: Translated: 572; Mature: 572

Protein sequence:

>572_residues
MRTHSYSLRRMTLSTKVILLAMLAVTVTAGAIWITVSRQTWSQMEARQRTNGERNLRTLALVLAARVEGAAADLDGARVA
RVSTPSLSGFADAGVVDDAVAYSGGLATVFSYEPASDSFVRRQTTVRREDGTRAVGTALAADSPAQAAIRAGRTYEGPAA
LFGRRYYTVYHPTVDTTGKVNGILFVGLPIEMYFDAHAQTMTSLSVAALVIAVLACALVGLAAARLFRPFATIAARIEAL
AAGDLDSAIPHAGRGDEIGTVARALEVLRVAGLRTRELESLQSAGAADETRRRAALDRAIEAFRGQVVRLKDALTASTGA
MRARAGEMAASSAEAEVAVAETERGSHETSASVQTVASAAEELSASIAEIGTQLDQAEALVATTAAESDAMNAEIGELAE
AAGRIGAVVGLIRQIAEQTNLLALNATIESARAGAAGKGFAVVAAEVKALASQTAKATEEIGSQIAGVQASTTAAVAAIG
RMGERMRAVSATTGGIASAVSAQGAATAEISRNVADTAGATEAIAGGLTTVAGAARRSARMAATVTDAAQTVDTVAADLE
AEIERFLGQVAA

Sequences:

>Translated_572_residues
MRTHSYSLRRMTLSTKVILLAMLAVTVTAGAIWITVSRQTWSQMEARQRTNGERNLRTLALVLAARVEGAAADLDGARVA
RVSTPSLSGFADAGVVDDAVAYSGGLATVFSYEPASDSFVRRQTTVRREDGTRAVGTALAADSPAQAAIRAGRTYEGPAA
LFGRRYYTVYHPTVDTTGKVNGILFVGLPIEMYFDAHAQTMTSLSVAALVIAVLACALVGLAAARLFRPFATIAARIEAL
AAGDLDSAIPHAGRGDEIGTVARALEVLRVAGLRTRELESLQSAGAADETRRRAALDRAIEAFRGQVVRLKDALTASTGA
MRARAGEMAASSAEAEVAVAETERGSHETSASVQTVASAAEELSASIAEIGTQLDQAEALVATTAAESDAMNAEIGELAE
AAGRIGAVVGLIRQIAEQTNLLALNATIESARAGAAGKGFAVVAAEVKALASQTAKATEEIGSQIAGVQASTTAAVAAIG
RMGERMRAVSATTGGIASAVSAQGAATAEISRNVADTAGATEAIAGGLTTVAGAARRSARMAATVTDAAQTVDTVAADLE
AEIERFLGQVAA
>Mature_572_residues
MRTHSYSLRRMTLSTKVILLAMLAVTVTAGAIWITVSRQTWSQMEARQRTNGERNLRTLALVLAARVEGAAADLDGARVA
RVSTPSLSGFADAGVVDDAVAYSGGLATVFSYEPASDSFVRRQTTVRREDGTRAVGTALAADSPAQAAIRAGRTYEGPAA
LFGRRYYTVYHPTVDTTGKVNGILFVGLPIEMYFDAHAQTMTSLSVAALVIAVLACALVGLAAARLFRPFATIAARIEAL
AAGDLDSAIPHAGRGDEIGTVARALEVLRVAGLRTRELESLQSAGAADETRRRAALDRAIEAFRGQVVRLKDALTASTGA
MRARAGEMAASSAEAEVAVAETERGSHETSASVQTVASAAEELSASIAEIGTQLDQAEALVATTAAESDAMNAEIGELAE
AAGRIGAVVGLIRQIAEQTNLLALNATIESARAGAAGKGFAVVAAEVKALASQTAKATEEIGSQIAGVQASTTAAVAAIG
RMGERMRAVSATTGGIASAVSAQGAATAEISRNVADTAGATEAIAGGLTTVAGAARRSARMAATVTDAAQTVDTVAADLE
AEIERFLGQVAA

Specific function: Chemotactic-signal transducers respond to changes in the concentration of attractants and repellents in the environment, transduce a signal from the outside to the inside of the cell, and facilitate sensory adaptation through the variation of the level of

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein. Note=Localized at the flagellum-bearing pole of the swarmer cell [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 methyl-accepting transducer domain [H]

Homologues:

Organism=Escherichia coli, GI1789453, Length=342, Percent_Identity=29.8245614035088, Blast_Score=105, Evalue=1e-23,
Organism=Escherichia coli, GI1787690, Length=264, Percent_Identity=27.6515151515151, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1788194, Length=287, Percent_Identity=29.2682926829268, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI2367378, Length=406, Percent_Identity=27.0935960591133, Blast_Score=80, Evalue=5e-16,
Organism=Escherichia coli, GI1788195, Length=295, Percent_Identity=27.7966101694915, Blast_Score=75, Evalue=9e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004090
- InterPro:   IPR004089
- InterPro:   IPR003660 [H]

Pfam domain/function: PF00672 HAMP; PF00015 MCPsignal [H]

EC number: NA

Molecular weight: Translated: 58573; Mature: 58573

Theoretical pI: Translated: 5.43; Mature: 5.43

Prosite motif: PS50885 HAMP ; PS50111 CHEMOTAXIS_TRANSDUC_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTHSYSLRRMTLSTKVILLAMLAVTVTAGAIWITVSRQTWSQMEARQRTNGERNLRTLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHCCCHHHHHHHH
LVLAARVEGAAADLDGARVARVSTPSLSGFADAGVVDDAVAYSGGLATVFSYEPASDSFV
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHH
RRQTTVRREDGTRAVGTALAADSPAQAAIRAGRTYEGPAALFGRRYYTVYHPTVDTTGKV
HHHHHHHHCCCCHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHCCEEEEEECCCCCCCCCC
NGILFVGLPIEMYFDAHAQTMTSLSVAALVIAVLACALVGLAAARLFRPFATIAARIEAL
CEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGDLDSAIPHAGRGDEIGTVARALEVLRVAGLRTRELESLQSAGAADETRRRAALDRAI
HCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
EAFRGQVVRLKDALTASTGAMRARAGEMAASSAEAEVAVAETERGSHETSASVQTVASAA
HHHCCCEEEEHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
EELSASIAEIGTQLDQAEALVATTAAESDAMNAEIGELAEAAGRIGAVVGLIRQIAEQTN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLALNATIESARAGAAGKGFAVVAAEVKALASQTAKATEEIGSQIAGVQASTTAAVAAIG
EEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RMGERMRAVSATTGGIASAVSAQGAATAEISRNVADTAGATEAIAGGLTTVAGAARRSAR
HHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHH
MAATVTDAAQTVDTVAADLEAEIERFLGQVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MRTHSYSLRRMTLSTKVILLAMLAVTVTAGAIWITVSRQTWSQMEARQRTNGERNLRTLA
CCCCCCHHHHHHHHHHHHHHHHHHHHHHCCEEEEEEEHHHHHHHHHHHHCCCHHHHHHHH
LVLAARVEGAAADLDGARVARVSTPSLSGFADAGVVDDAVAYSGGLATVFSYEPASDSFV
HHHHHHHCCCCCCCCCCEEEEECCCCCCCCCCCCCHHHHHHHCCCEEEEEECCCCCCHHH
RRQTTVRREDGTRAVGTALAADSPAQAAIRAGRTYEGPAALFGRRYYTVYHPTVDTTGKV
HHHHHHHHCCCCHHHHHHHHCCCCHHHHHHCCCCCCCHHHHHCCEEEEEECCCCCCCCCC
NGILFVGLPIEMYFDAHAQTMTSLSVAALVIAVLACALVGLAAARLFRPFATIAARIEAL
CEEEEEECCCEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AAGDLDSAIPHAGRGDEIGTVARALEVLRVAGLRTRELESLQSAGAADETRRRAALDRAI
HCCCCHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHHHHHHCCCCHHHHHHHHHHHHH
EAFRGQVVRLKDALTASTGAMRARAGEMAASSAEAEVAVAETERGSHETSASVQTVASAA
HHHCCCEEEEHHHHHHCHHHHHHHHHHHHHCCCCCEEEEEECCCCCCHHHHHHHHHHHHH
EELSASIAEIGTQLDQAEALVATTAAESDAMNAEIGELAEAAGRIGAVVGLIRQIAEQTN
HHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
LLALNATIESARAGAAGKGFAVVAAEVKALASQTAKATEEIGSQIAGVQASTTAAVAAIG
EEEEECCHHHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHH
RMGERMRAVSATTGGIASAVSAQGAATAEISRNVADTAGATEAIAGGLTTVAGAARRSAR
HHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHCCCHHHHHCCHHHHHHHHHHHHH
MAATVTDAAQTVDTVAADLEAEIERFLGQVAA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1577276; 11259647 [H]