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The map label for this gene is arsR [C]

Identifier: 170748543

GI number: 170748543

Start: 2265289

End: 2266308

Strand: Reverse

Name: arsR [C]

Synonym: Mrad2831_2125

Alternate gene names: 170748543

Gene position: 2266308-2265289 (Counterclockwise)

Preceding gene: 170748545

Following gene: 170748542

Centisome position: 37.29

GC content: 74.22

Gene sequence:

>1020_bases
ATGTCTATCGAACGCAGGCAAGAGGCGGGGTCGATCCCCTTTCCGGAAGCCCTGGGCGTCCTGCGTGCGGCCGCGGAGGA
GACGCGCCTGCGCATCCTGGCGCTCCTCGTCGAGGGTGAGCTGTCGGTCTCCGACCTCACCGACATCCTCGGCCAGTCCC
AGCCGCGGATCTCCCGCCACCTTAAGCTCCTGGTGGAGGCAGGGCTGGTCGAGCGCCACCGCGAGGGGGCCTGGGCGTTC
TTCCGGCTGTCCGACGCCCGCGCCGGCCTGGCGGACCCGCTGCTGTCCGGGCTCGACCGGACCGCGCCGCCGCTCTCGGA
GGACCGCGCGCGGCTCGACGCCGTCCGGGCGCAGCGGGCCGAGGCGGCCACGACCTTCTTCGCCCGGCTGGCTCCCAAAT
GGGACGAGCTGCGCTGCCTGCACGTGCCCGAGGCGATCGTGGAGGCCGCGGTGCTCGACGCCCTGGGCGACCGCCCGATC
GGCAGCCTGATCGATCTCGGGACCGGCACCGGCCGGATGCTCGGCCTCCTGGCGCCCCGGGCCAGCCGGGCCACCGGCCT
CGATTCGAGCCACGCCATGCTGTCCGTCGCCCGGGCCAACCTGGAGCGCCAGGGCCTCGCGCGGGTCGATCTGCGGCAGG
GCGACATTCACGCGCCGCCCTTCGCGCGGGCGAGTTTCGACCTCGTCGTGGTCCATCAGGTGCTGCATTATCTCGACGAC
CCGGCCCGGGCGCTCCGCGGCGCCGCGCGGCTTGTGGCGCCGGGCGGCCGCCTGCTGGTGGTGGATTTCGCGCCGCACGA
TCTGGAGTTCCTGCGCACCGGACAGGCCCACCGGCGCCTCGGCTTCTCGGCCGACCAGGTCTCCGGCTGGCTCGCCGAGG
CCGGCCTCGCCACGGTCGCCACCCGCGATCTGGCGCCGCGCGAGTCCGGCCAGCTCACCGTCACCCTCTGGCTGGCCCAG
GACGGGCTGGCCCAAGACGGGCTGACCGACACAGAACAGCCTCAGCGCGCCGTCGCCTGA

Upstream 100 bases:

>100_bases
GCGGCCGCCGCGCTACCGTCTCATCGGCTCGGCACGATCGCCTCAGGCCGATTCAAGATCGCGCTTGCGTCCGCGTCGAA
ACGGACATAAACATATCTTT

Downstream 100 bases:

>100_bases
GACACCGAACTCCGCAGACTTCGTCTGAACCGACCGACATAGAGGACGAGACCCCGATGCGCCGCTCCACCCACCGCGCC
AGCCGCGACGGCTACCACCC

Product: ArsR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 339; Mature: 338

Protein sequence:

>339_residues
MSIERRQEAGSIPFPEALGVLRAAAEETRLRILALLVEGELSVSDLTDILGQSQPRISRHLKLLVEAGLVERHREGAWAF
FRLSDARAGLADPLLSGLDRTAPPLSEDRARLDAVRAQRAEAATTFFARLAPKWDELRCLHVPEAIVEAAVLDALGDRPI
GSLIDLGTGTGRMLGLLAPRASRATGLDSSHAMLSVARANLERQGLARVDLRQGDIHAPPFARASFDLVVVHQVLHYLDD
PARALRGAARLVAPGGRLLVVDFAPHDLEFLRTGQAHRRLGFSADQVSGWLAEAGLATVATRDLAPRESGQLTVTLWLAQ
DGLAQDGLTDTEQPQRAVA

Sequences:

>Translated_339_residues
MSIERRQEAGSIPFPEALGVLRAAAEETRLRILALLVEGELSVSDLTDILGQSQPRISRHLKLLVEAGLVERHREGAWAF
FRLSDARAGLADPLLSGLDRTAPPLSEDRARLDAVRAQRAEAATTFFARLAPKWDELRCLHVPEAIVEAAVLDALGDRPI
GSLIDLGTGTGRMLGLLAPRASRATGLDSSHAMLSVARANLERQGLARVDLRQGDIHAPPFARASFDLVVVHQVLHYLDD
PARALRGAARLVAPGGRLLVVDFAPHDLEFLRTGQAHRRLGFSADQVSGWLAEAGLATVATRDLAPRESGQLTVTLWLAQ
DGLAQDGLTDTEQPQRAVA
>Mature_338_residues
SIERRQEAGSIPFPEALGVLRAAAEETRLRILALLVEGELSVSDLTDILGQSQPRISRHLKLLVEAGLVERHREGAWAFF
RLSDARAGLADPLLSGLDRTAPPLSEDRARLDAVRAQRAEAATTFFARLAPKWDELRCLHVPEAIVEAAVLDALGDRPIG
SLIDLGTGTGRMLGLLAPRASRATGLDSSHAMLSVARANLERQGLARVDLRQGDIHAPPFARASFDLVVVHQVLHYLDDP
ARALRGAARLVAPGGRLLVVDFAPHDLEFLRTGQAHRRLGFSADQVSGWLAEAGLATVATRDLAPRESGQLTVTLWLAQD
GLAQDGLTDTEQPQRAVA

Specific function: Transcriptional Repressor For The Arsefg Operon. Arse Is A Trans-Acting Regulatory Protein Which Controls Its Own Expression. The Repressive Effect Of Arse Is Alleviated By Oxyions Of +III Oxidation State Of Arsenic, Antimony, And Bismuth, As Well As Arse

COG id: COG0500

COG function: function code QR; SAM-dependent methyltransferases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the methyltransferase superfamily [H]

Homologues:

Organism=Escherichia coli, GI1789916, Length=74, Percent_Identity=48.6486486486487, Blast_Score=65, Evalue=4e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013216
- InterPro:   IPR005149
- InterPro:   IPR011991 [H]

Pfam domain/function: PF08241 Methyltransf_11; PF03551 PadR [H]

EC number: NA

Molecular weight: Translated: 36585; Mature: 36454

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS00012 PHOSPHOPANTETHEINE ; PS50987 HTH_ARSR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.9 %Met     (Translated Protein)
1.2 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.6 %Met     (Mature Protein)
0.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIERRQEAGSIPFPEALGVLRAAAEETRLRILALLVEGELSVSDLTDILGQSQPRISRH
CCCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHEEHHCCCCCHHHHHHHHCCCCHHHHHH
LKLLVEAGLVERHREGAWAFFRLSDARAGLADPLLSGLDRTAPPLSEDRARLDAVRAQRA
HHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
EAATTFFARLAPKWDELRCLHVPEAIVEAAVLDALGDRPIGSLIDLGTGTGRMLGLLAPR
HHHHHHHHHHCCCHHHEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHCCC
ASRATGLDSSHAMLSVARANLERQGLARVDLRQGDIHAPPFARASFDLVVVHQVLHYLDD
CHHCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PARALRGAARLVAPGGRLLVVDFAPHDLEFLRTGQAHRRLGFSADQVSGWLAEAGLATVA
HHHHHHHHHHEECCCCCEEEEECCCCCHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHH
TRDLAPRESGQLTVTLWLAQDGLAQDGLTDTEQPQRAVA
HHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHCCC
>Mature Secondary Structure 
SIERRQEAGSIPFPEALGVLRAAAEETRLRILALLVEGELSVSDLTDILGQSQPRISRH
CCCCCHHCCCCCCHHHHHHHHHHHHHHHHHHHEEHHCCCCCHHHHHHHHCCCCHHHHHH
LKLLVEAGLVERHREGAWAFFRLSDARAGLADPLLSGLDRTAPPLSEDRARLDAVRAQRA
HHHHHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHH
EAATTFFARLAPKWDELRCLHVPEAIVEAAVLDALGDRPIGSLIDLGTGTGRMLGLLAPR
HHHHHHHHHHCCCHHHEEEEECCHHHHHHHHHHHHCCCCCHHHHHCCCCCCHHHHHHCCC
ASRATGLDSSHAMLSVARANLERQGLARVDLRQGDIHAPPFARASFDLVVVHQVLHYLDD
CHHCCCCCCHHHHHHHHHHHHHHCCCEEEECCCCCCCCCCCCCCCHHHHHHHHHHHHHCC
PARALRGAARLVAPGGRLLVVDFAPHDLEFLRTGQAHRRLGFSADQVSGWLAEAGLATVA
HHHHHHHHHHEECCCCCEEEEECCCCCHHHHHCCHHHHHCCCCHHHHHHHHHHHHHHHHH
TRDLAPRESGQLTVTLWLAQDGLAQDGLTDTEQPQRAVA
HHCCCCCCCCCEEEEEEEECCCCCCCCCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2155856 [H]