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The map label for this gene is xerD [H]

Identifier: 170747111

GI number: 170747111

Start: 722043

End: 722918

Strand: Reverse

Name: xerD [H]

Synonym: Mrad2831_0677

Alternate gene names: 170747111

Gene position: 722918-722043 (Counterclockwise)

Preceding gene: 170747112

Following gene: 170747110

Centisome position: 11.89

GC content: 73.17

Gene sequence:

>876_bases
ATGCTGGCCGCCGAACGCGGGGCCGGCCTCAACACCCTGAGCGCCTACCGGCGGGACCTCGACGACTACCTCGGTTATCT
CGCGCGCTCGGGCACGGCGCTCGGCGACGTGGATGCCGGCACGCTGCGAGCCTTCCTCATCGACCTCGAGACGCGGGGCC
TGAAGGCGTCCTCGGCGGCGCGGCGCCTGTCCTGCGTCCGCGGTTTCCACAAGTTCCTGTACGCCGAGGGCGGTGCCGAG
AGCGATCCGAGCGTCGCGGTGTCCGGTCCGCGCCGGGGACGCGCGCTCCCCAAGGTGCTGTCGATCGCGGAGGTCGACCG
GCTGCTCGCCACGGCGCAGGCCGCCGCCGGCGCCGACCAGCCTCCGGGCCCGGCCCGCCGGGCGCGCCGGATGGTGTGCC
TGCTCGAGCTGCTCTACGCCACGGGCCTGCGCGTCTCGGAACTGGTCGCCCTGCCCCGCACGGCGGGCGCGAGTCGCGAG
CGCTACCTGATCGTCAGGGGCAAGGGCGGCCGCGAGCGCCTCGTGCCCCTGACCGAGGCGGCCCGCGCCGCCATGGCGGC
GCATCTTCCGGCCGTGCCGGAGGATTCCCCGTGGCTGTTTCCCGCCGACAGCGACAGCGGCTACCTCACCCGGCAGGCCT
TCGCCCGCGATCTCAAGGTGCTGGCCGCGGCGGCCGGTCTCCACCCGGACCGCGTGAGCCCCCACGTGCTCCGCCACGCC
TTCGCCAGTCACCTCCTGCAGAACGGCGCCGACCTGCGCATCGTCCAAGAGCTTCTCGGCCATGCCGACATCTCGACGAC
GCAGATCTACACGCACGTGCTCGACGAGCGCCTGAAGGCGATGGTCCGCGATCTGCATCCGCTGATGGATCGCTGA

Upstream 100 bases:

>100_bases
TCCCCGCCTCGAAGCTGCAGCCGGGCAACCGTTGAGCGGGTCTGAGAGCGGCGGCGACGCCGCCCGGGCACCCCGTCCCG
AGGTCGCCGAGTACCTCGAC

Downstream 100 bases:

>100_bases
GCGGTCCCGCGCGGAACGCCTGGCAACTCCTGGTGGGTCGCCCCAATTGTATAGGTTTAGCGAACTGCCTAAGAGTAGCC
CCTCGCCATACCGGTACGCG

Product: integrase family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 291; Mature: 291

Protein sequence:

>291_residues
MLAAERGAGLNTLSAYRRDLDDYLGYLARSGTALGDVDAGTLRAFLIDLETRGLKASSAARRLSCVRGFHKFLYAEGGAE
SDPSVAVSGPRRGRALPKVLSIAEVDRLLATAQAAAGADQPPGPARRARRMVCLLELLYATGLRVSELVALPRTAGASRE
RYLIVRGKGGRERLVPLTEAARAAMAAHLPAVPEDSPWLFPADSDSGYLTRQAFARDLKVLAAAAGLHPDRVSPHVLRHA
FASHLLQNGADLRIVQELLGHADISTTQIYTHVLDERLKAMVRDLHPLMDR

Sequences:

>Translated_291_residues
MLAAERGAGLNTLSAYRRDLDDYLGYLARSGTALGDVDAGTLRAFLIDLETRGLKASSAARRLSCVRGFHKFLYAEGGAE
SDPSVAVSGPRRGRALPKVLSIAEVDRLLATAQAAAGADQPPGPARRARRMVCLLELLYATGLRVSELVALPRTAGASRE
RYLIVRGKGGRERLVPLTEAARAAMAAHLPAVPEDSPWLFPADSDSGYLTRQAFARDLKVLAAAAGLHPDRVSPHVLRHA
FASHLLQNGADLRIVQELLGHADISTTQIYTHVLDERLKAMVRDLHPLMDR
>Mature_291_residues
MLAAERGAGLNTLSAYRRDLDDYLGYLARSGTALGDVDAGTLRAFLIDLETRGLKASSAARRLSCVRGFHKFLYAEGGAE
SDPSVAVSGPRRGRALPKVLSIAEVDRLLATAQAAAGADQPPGPARRARRMVCLLELLYATGLRVSELVALPRTAGASRE
RYLIVRGKGGRERLVPLTEAARAAMAAHLPAVPEDSPWLFPADSDSGYLTRQAFARDLKVLAAAAGLHPDRVSPHVLRHA
FASHLLQNGADLRIVQELLGHADISTTQIYTHVLDERLKAMVRDLHPLMDR

Specific function: Site-specific tyrosine recombinase, which acts by catalyzing the cutting and rejoining of the recombining DNA molecules. The xerC-xerD complex is essential to convert dimers of the bacterial chromosome into monomers to permit their segregation at cell div

COG id: COG4974

COG function: function code L; Site-specific recombinase XerD

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 'phage' integrase family. XerD subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789261, Length=295, Percent_Identity=44.4067796610169, Blast_Score=208, Evalue=3e-55,
Organism=Escherichia coli, GI1790244, Length=293, Percent_Identity=33.7883959044369, Blast_Score=140, Evalue=8e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011010
- InterPro:   IPR013762
- InterPro:   IPR002104
- InterPro:   IPR010998
- InterPro:   IPR023109
- InterPro:   IPR004107
- InterPro:   IPR011932 [H]

Pfam domain/function: PF02899 Phage_integr_N; PF00589 Phage_integrase [H]

EC number: NA

Molecular weight: Translated: 31407; Mature: 31407

Theoretical pI: Translated: 9.94; Mature: 9.94

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.7 %Met     (Mature Protein)
2.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLAAERGAGLNTLSAYRRDLDDYLGYLARSGTALGDVDAGTLRAFLIDLETRGLKASSAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHH
RRLSCVRGFHKFLYAEGGAESDPSVAVSGPRRGRALPKVLSIAEVDRLLATAQAAAGADQ
HHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PPGPARRARRMVCLLELLYATGLRVSELVALPRTAGASRERYLIVRGKGGRERLVPLTEA
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHH
ARAAMAAHLPAVPEDSPWLFPADSDSGYLTRQAFARDLKVLAAAAGLHPDRVSPHVLRHA
HHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FASHLLQNGADLRIVQELLGHADISTTQIYTHVLDERLKAMVRDLHPLMDR
HHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MLAAERGAGLNTLSAYRRDLDDYLGYLARSGTALGDVDAGTLRAFLIDLETRGLKASSAA
CCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHCCCCHHHHH
RRLSCVRGFHKFLYAEGGAESDPSVAVSGPRRGRALPKVLSIAEVDRLLATAQAAAGADQ
HHHHHHHHHHHHHHHCCCCCCCCCEEECCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCC
PPGPARRARRMVCLLELLYATGLRVSELVALPRTAGASRERYLIVRGKGGRERLVPLTEA
CCCHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCCCCCCCEEEEECCCCCCCCCCHHHH
ARAAMAAHLPAVPEDSPWLFPADSDSGYLTRQAFARDLKVLAAAAGLHPDRVSPHVLRHA
HHHHHHHHCCCCCCCCCEEEECCCCCCHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHH
FASHLLQNGADLRIVQELLGHADISTTQIYTHVLDERLKAMVRDLHPLMDR
HHHHHHHCCCHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 12597275 [H]