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The map label for this gene is yecS [H]

Identifier: 170746805

GI number: 170746805

Start: 393967

End: 394620

Strand: Reverse

Name: yecS [H]

Synonym: Mrad2831_0359

Alternate gene names: 170746805

Gene position: 394620-393967 (Counterclockwise)

Preceding gene: 170746806

Following gene: 170746804

Centisome position: 6.49

GC content: 65.29

Gene sequence:

>654_bases
ATGCGCGAGTTCCTCGCCGACGCCCAGGACTACCTGCCGATCCTGCTGCAGGGCGTGCAGCTCACGATCCTGATCACGAT
CGCGTCCCTGGTGGTCTCGACGCTGCTGGGGCTGGTCTGGGCGGTGATGCGGGTCTCCGGCATCGCGATCCTGTCGGGCT
TCAGCGCGGTGATGATCAACATCCTGCGCGGCATCCCGATCATCGTGCAGTTGTTCTACATCTACTTCGTGATGCCCGAT
TTCGGCCTGTCGCTCACCGCCGTCCAGGCGGCGATCATCGGGCTCGGCATCGCCTACTCGGCCTATCAGGCCGAGAACTT
CCGCGCCGGCATCGAGGCGGTGGATCGCGGCCAGGTCGAGGCGGCGCTGTCGATCGGCATGGGCTGGGGCATGACCATGC
GGCGGGTGATCCTGCCGCAGGCGATCCGGATCGCGCTGCCGCCCTACGGCAACATCATGATCATGATGCTCAAGGACTCG
TCGCAGGCCTCGACCATCACGGTCGCCGAGCTGGCGCTCCAGGGAAAGCTGATCGCGTCGTCGACCTTCAAGAACACCAG
TGTCTACACGCTGGTGGCGCTGATGTACCTCGCGCTCAGCCTGCCGCTGATCCTGCTGGTCCGCCACTTCGAGGCGAAGG
GGCGGCACCGATGA

Upstream 100 bases:

>100_bases
AGATCGACGCGGCGCTCGCCAAGCTGAAAGCCGACGGGACGCTCCAGGCGATCCTCACCAAGTGGGGTCTGCCGCCGTCG
GCCGACCGGTCCTGACCTTC

Downstream 100 bases:

>100_bases
TCGTGCTGGAGGACGTCCGGAAGCATTACGGCGCGCTGGAGGTGATCAAGGGCGTCTCGGCCGAGGTCACGAAGGGCGAG
GTCGTCTGCATCATCGGGCC

Product: polar amino acid ABC transporter inner membrane protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 217; Mature: 217

Protein sequence:

>217_residues
MREFLADAQDYLPILLQGVQLTILITIASLVVSTLLGLVWAVMRVSGIAILSGFSAVMINILRGIPIIVQLFYIYFVMPD
FGLSLTAVQAAIIGLGIAYSAYQAENFRAGIEAVDRGQVEAALSIGMGWGMTMRRVILPQAIRIALPPYGNIMIMMLKDS
SQASTITVAELALQGKLIASSTFKNTSVYTLVALMYLALSLPLILLVRHFEAKGRHR

Sequences:

>Translated_217_residues
MREFLADAQDYLPILLQGVQLTILITIASLVVSTLLGLVWAVMRVSGIAILSGFSAVMINILRGIPIIVQLFYIYFVMPD
FGLSLTAVQAAIIGLGIAYSAYQAENFRAGIEAVDRGQVEAALSIGMGWGMTMRRVILPQAIRIALPPYGNIMIMMLKDS
SQASTITVAELALQGKLIASSTFKNTSVYTLVALMYLALSLPLILLVRHFEAKGRHR
>Mature_217_residues
MREFLADAQDYLPILLQGVQLTILITIASLVVSTLLGLVWAVMRVSGIAILSGFSAVMINILRGIPIIVQLFYIYFVMPD
FGLSLTAVQAAIIGLGIAYSAYQAENFRAGIEAVDRGQVEAALSIGMGWGMTMRRVILPQAIRIALPPYGNIMIMMLKDS
SQASTITVAELALQGKLIASSTFKNTSVYTLVALMYLALSLPLILLVRHFEAKGRHR

Specific function: Probably part of the binding-protein-dependent transport system yecCS for an amino acid; probably responsible for the translocation of the substrate across the membrane [H]

COG id: COG0765

COG function: function code E; ABC-type amino acid transport system, permease component

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 ABC transmembrane type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1788226, Length=213, Percent_Identity=43.1924882629108, Blast_Score=165, Evalue=2e-42,
Organism=Escherichia coli, GI1787030, Length=204, Percent_Identity=35.2941176470588, Blast_Score=117, Evalue=6e-28,
Organism=Escherichia coli, GI1786873, Length=210, Percent_Identity=30.4761904761905, Blast_Score=101, Evalue=3e-23,
Organism=Escherichia coli, GI1786874, Length=219, Percent_Identity=31.0502283105023, Blast_Score=98, Evalue=3e-22,
Organism=Escherichia coli, GI1788645, Length=208, Percent_Identity=31.25, Blast_Score=89, Evalue=2e-19,
Organism=Escherichia coli, GI1787087, Length=217, Percent_Identity=28.110599078341, Blast_Score=85, Evalue=4e-18,
Organism=Escherichia coli, GI1787086, Length=216, Percent_Identity=27.7777777777778, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI87082239, Length=202, Percent_Identity=29.7029702970297, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788646, Length=203, Percent_Identity=28.5714285714286, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI48994930, Length=125, Percent_Identity=33.6, Blast_Score=64, Evalue=5e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR010065
- InterPro:   IPR000515 [H]

Pfam domain/function: PF00528 BPD_transp_1 [H]

EC number: NA

Molecular weight: Translated: 23619; Mature: 23619

Theoretical pI: Translated: 9.80; Mature: 9.80

Prosite motif: PS50928 ABC_TM1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
5.1 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
5.1 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MREFLADAQDYLPILLQGVQLTILITIASLVVSTLLGLVWAVMRVSGIAILSGFSAVMIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILRGIPIIVQLFYIYFVMPDFGLSLTAVQAAIIGLGIAYSAYQAENFRAGIEAVDRGQVE
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AALSIGMGWGMTMRRVILPQAIRIALPPYGNIMIMMLKDSSQASTITVAELALQGKLIAS
HHHHHCCCCCHHHHHHHHHHHHEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHCHHHCC
STFKNTSVYTLVALMYLALSLPLILLVRHFEAKGRHR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
>Mature Secondary Structure
MREFLADAQDYLPILLQGVQLTILITIASLVVSTLLGLVWAVMRVSGIAILSGFSAVMIN
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ILRGIPIIVQLFYIYFVMPDFGLSLTAVQAAIIGLGIAYSAYQAENFRAGIEAVDRGQVE
HHCCHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHH
AALSIGMGWGMTMRRVILPQAIRIALPPYGNIMIMMLKDSSQASTITVAELALQGKLIAS
HHHHHCCCCCHHHHHHHHHHHHEEECCCCCCEEEEEEECCCCCHHHHHHHHHHHCHHHCC
STFKNTSVYTLVALMYLALSLPLILLVRHFEAKGRHR
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]