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The map label for this gene is dgdR [H]

Identifier: 170746748

GI number: 170746748

Start: 326170

End: 327054

Strand: Reverse

Name: dgdR [H]

Synonym: Mrad2831_0301

Alternate gene names: 170746748

Gene position: 327054-326170 (Counterclockwise)

Preceding gene: 170746750

Following gene: 170746747

Centisome position: 5.38

GC content: 72.32

Gene sequence:

>885_bases
ATGGCCGCGCGCACCAATCTCGACATGGACGTGCTCAGAACCTTCGTGACCGGGTTCGAGCTCGGCAGCTTCGCCCGCGC
GGCCGAGCGGCTGGGACGGTCACAATCCGCCGTCAGCACCCAGCTCCGGAAGCTGGAGGAGCAGGTCGGGCAGCCGCTCG
TGCAGAAGGCCGGACGCGGCCTCGCGCTGACAGCCGCCGGCGAGAGCATGCTCGGCTACGCGAAGCGGCTTCTGGAGCTC
AACGACGAGGCGGTCGACCGACTGCGCGGAACGGAACTCGAAGGCTGGGCGCGGCTGGGCCTCGCGCAGGATTTCGCCGA
GAGCTGGCTCCCGGCGGTGCTCAAGCGGTTCTCGCGGGCCTATCCGAGGGTGCGCATCGAGGTGCAGGTCGGGCTCGGCG
CGCAGCTCATCGAGAAGGCCCTGAAGGACGAGCTCGACGTGGCGCTGGTCTGGGGCGACGGCGGCGGCGCCCCTCACGCG
CAGCGGGTTGCGGACGTGCCGATCCGCTGGATCGGCCCGCCGGACTGGCCGGGTCTCGCAGGTCTCGGGCGGGAACCCGT
TCCCCTCGCGGCCTTCGCCCCGCCGTGCACCTTCAGGTCCGCGGCCGTGTCTGCCCTGGACGCTCGCGGCCTGCCCTGGC
GGCTGGTCTTCACGAGCCCCAGCCTCTCGGGCCTCTGGGCCGCAGCCGAGGGTGGCCTCGGCATCACCGCGCGCACCGCG
GTCGGCCTGCCGAAGACGCTGAGCGTCCTCGACCCCGCCGCGACCGGCCTGCCACCCCTCCCGAACGCCGCTCTGACGCT
CCATCAGGCGGAAGCCGAGCTGTCGCCGGCCGTCGCGCGCTTGACCGATATCCTTCTCGAAACGATCGGCGCTCACGTGG
CGTGA

Upstream 100 bases:

>100_bases
TCTCGGCACGATCCGGCCGGCTTGACGCCTCCCCGATACCTGCCCATCATCGTCCGGAATATTTGAATATTCGAAATTGA
ACCTTCCGTAAAACCGAACG

Downstream 100 bases:

>100_bases
GGCGGAGACTTCCTTCGCTCAGTCCTCGCCGAGAATAGCGGCTGCTCCCGGGAAATCGGGAAGCGCCGTCGTGACGGGTG
TCAACGGAGAGACCGACCTT

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: 2,2-dialkylglycine decarboxylase repressor [H]

Number of amino acids: Translated: 294; Mature: 293

Protein sequence:

>294_residues
MAARTNLDMDVLRTFVTGFELGSFARAAERLGRSQSAVSTQLRKLEEQVGQPLVQKAGRGLALTAAGESMLGYAKRLLEL
NDEAVDRLRGTELEGWARLGLAQDFAESWLPAVLKRFSRAYPRVRIEVQVGLGAQLIEKALKDELDVALVWGDGGGAPHA
QRVADVPIRWIGPPDWPGLAGLGREPVPLAAFAPPCTFRSAAVSALDARGLPWRLVFTSPSLSGLWAAAEGGLGITARTA
VGLPKTLSVLDPAATGLPPLPNAALTLHQAEAELSPAVARLTDILLETIGAHVA

Sequences:

>Translated_294_residues
MAARTNLDMDVLRTFVTGFELGSFARAAERLGRSQSAVSTQLRKLEEQVGQPLVQKAGRGLALTAAGESMLGYAKRLLEL
NDEAVDRLRGTELEGWARLGLAQDFAESWLPAVLKRFSRAYPRVRIEVQVGLGAQLIEKALKDELDVALVWGDGGGAPHA
QRVADVPIRWIGPPDWPGLAGLGREPVPLAAFAPPCTFRSAAVSALDARGLPWRLVFTSPSLSGLWAAAEGGLGITARTA
VGLPKTLSVLDPAATGLPPLPNAALTLHQAEAELSPAVARLTDILLETIGAHVA
>Mature_293_residues
AARTNLDMDVLRTFVTGFELGSFARAAERLGRSQSAVSTQLRKLEEQVGQPLVQKAGRGLALTAAGESMLGYAKRLLELN
DEAVDRLRGTELEGWARLGLAQDFAESWLPAVLKRFSRAYPRVRIEVQVGLGAQLIEKALKDELDVALVWGDGGGAPHAQ
RVADVPIRWIGPPDWPGLAGLGREPVPLAAFAPPCTFRSAAVSALDARGLPWRLVFTSPSLSGLWAAAEGGLGITARTAV
GLPKTLSVLDPAATGLPPLPNAALTLHQAEAELSPAVARLTDILLETIGAHVA

Specific function: Not Known, Does Not Seem To Act On The Proton Translocating NADH Dehydrogenase Genes (Nuoa-N) Which Are Part Of The Lrha Operon. [C]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1788626, Length=262, Percent_Identity=36.2595419847328, Blast_Score=157, Evalue=6e-40,
Organism=Escherichia coli, GI1787806, Length=237, Percent_Identity=27.4261603375527, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI1789173, Length=147, Percent_Identity=33.3333333333333, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI87082132, Length=295, Percent_Identity=24.406779661017, Blast_Score=74, Evalue=8e-15,
Organism=Escherichia coli, GI1788887, Length=145, Percent_Identity=37.2413793103448, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1790208, Length=146, Percent_Identity=32.8767123287671, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI157672245, Length=149, Percent_Identity=32.2147651006711, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI1787601, Length=156, Percent_Identity=29.4871794871795, Blast_Score=69, Evalue=4e-13,
Organism=Escherichia coli, GI1788297, Length=230, Percent_Identity=27.3913043478261, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1787879, Length=196, Percent_Identity=31.1224489795918, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788706, Length=151, Percent_Identity=33.7748344370861, Blast_Score=65, Evalue=7e-12,
Organism=Escherichia coli, GI1788481, Length=295, Percent_Identity=26.4406779661017, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1788748, Length=151, Percent_Identity=31.1258278145695, Blast_Score=62, Evalue=3e-11,
Organism=Escherichia coli, GI1786401, Length=173, Percent_Identity=28.9017341040462, Blast_Score=62, Evalue=4e-11,
Organism=Escherichia coli, GI1787589, Length=181, Percent_Identity=27.6243093922652, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 31122; Mature: 30991

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.4 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.7 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAARTNLDMDVLRTFVTGFELGSFARAAERLGRSQSAVSTQLRKLEEQVGQPLVQKAGRG
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCC
LALTAAGESMLGYAKRLLELNDEAVDRLRGTELEGWARLGLAQDFAESWLPAVLKRFSRA
EEEEECCHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
YPRVRIEVQVGLGAQLIEKALKDELDVALVWGDGGGAPHAQRVADVPIRWIGPPDWPGLA
CCEEEEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCCCEEECCCCCCCCCC
GLGREPVPLAAFAPPCTFRSAAVSALDARGLPWRLVFTSPSLSGLWAAAEGGLGITARTA
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCCEEEHHH
VGLPKTLSVLDPAATGLPPLPNAALTLHQAEAELSPAVARLTDILLETIGAHVA
CCCCHHHHHHCCHHCCCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
AARTNLDMDVLRTFVTGFELGSFARAAERLGRSQSAVSTQLRKLEEQVGQPLVQKAGRG
CCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCHHHHHCCCC
LALTAAGESMLGYAKRLLELNDEAVDRLRGTELEGWARLGLAQDFAESWLPAVLKRFSRA
EEEEECCHHHHHHHHHHHHCCHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHC
YPRVRIEVQVGLGAQLIEKALKDELDVALVWGDGGGAPHAQRVADVPIRWIGPPDWPGLA
CCEEEEEEEECCCHHHHHHHHHCCCCEEEEEECCCCCCHHHHHHCCCEEECCCCCCCCCC
GLGREPVPLAAFAPPCTFRSAAVSALDARGLPWRLVFTSPSLSGLWAAAEGGLGITARTA
CCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCEEEEEECCCCCCEEEECCCCCCEEEHHH
VGLPKTLSVLDPAATGLPPLPNAALTLHQAEAELSPAVARLTDILLETIGAHVA
CCCCHHHHHHCCHHCCCCCCCCHHEEEEHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2180928 [H]