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The map label for this gene is ytfL [C]

Identifier: 170746742

GI number: 170746742

Start: 318491

End: 319822

Strand: Reverse

Name: ytfL [C]

Synonym: Mrad2831_0295

Alternate gene names: 170746742

Gene position: 319822-318491 (Counterclockwise)

Preceding gene: 170746743

Following gene: 170746740

Centisome position: 5.26

GC content: 69.89

Gene sequence:

>1332_bases
TTGGACGACGGTTGGGCGACTGCCTTAGGGTTGTTTGCCGTCCTCGCCCTGGTTCTGGCGAACGGCTTCTTCGTGGCAGC
GGAATTCGCCCTGGTCGCGGTGCGCAGGAGCCGCGTGGCCGAACTCGTCGCCGAGCGGCGCGTGAACGCGAAGGCGCTGC
TCTGGGCCACGGACCACCTCGACGCCCACCTCGCGGCGACTCAGCTCGGCATCACCATCTCGTCCCTCGCGCTGGGCTGG
GTCGGCGAGCCGGCGCTGGCCCACCTGATCTTGCCCGCCCTGACGTGGCTGCCGGACATGCTCTCCACGGCGGCCGCGCA
CACGGTCGCGGTGGTGATCTCGTTCGTCATCATAACGGCGCTGCACATCGTGCTGGGTGAGCTGGCACCGAAGAGCCTCG
CGCTCCAGCGCAGCGAGCGCACGGCCCTCGCGGTGATCCGCCCGCTCAGCGTATTCCTGTTCGTGTTCCGCCCGGCCATC
CTGTTCCTGAACGGCCTCGGCAACGGCGTCCTGCGCCTCTGCGGATTGCAGCCCGGCCACGGCGAAGGTGGGCACCATTC
GACGGCGGAGCTCAATCTTCTGGTCGAGGCGAGCCGCGAGGCCGGCCTCATCCGCGAGGCGCAGCAGGAAGCGGTCGAGC
GCATCTTCCGATTGGGAGATCGGCGGGTCCGCGAGATCATGACGCCGCGCCACGAGGTCGAGTGGGTCGACCTCGACGGA
TCGCCCGAGGAGATCACGCGGGCGGTCCGCGCCTGCAGCCACGCCCATGTCTTGGTGAGCCGCGGCGGCATCGACGAGGT
CGTCGGCGTGCTGCGCAAGCAGGATCTGCTCGATCAGATCCTCGACGGGCAGCCCCTCGACATCGCCGCCGCCATGCGGC
CGCCGAACGTCGTCCACGAGGGCATGACGGTCCTCACGGCGCTGGAGAGCTTCCAGCGCAACCCCGTGCAGCTGGCGGTG
ATCGTCGACGAGTACGGCAGCCTGGAGGGGCTCGTCACGCAGACGGATCTCCTCGAGGCCATCGCGGGCGACATTCCCGA
GATCGGGGAGGATCCGGCCGTGGTCGAGCGCGAGGACGGCTCGCTCCTCATCGACGGCATGATGCCGGCCGAGGACGCGT
TCGAGCGCCTCGCCTTCACCGACCCGCCCGACACGGACGACTACACGACGCTGGCCGGCTACGTCATCTTCCAGCTCGGC
CGCATCCCGGCGGCGGGCGACGCCCTCGTCGCGGAGGGTTGGCGCCTCGAGGTGGTCGATATGGACGGCCGTCGCATCGA
CAAGGTCCTGGCCACCCGATTGCCGGGGCGGGCGCTGACCGGGACGGCGTGA

Upstream 100 bases:

>100_bases
GAGGCCGCTCGGGCCCGGAAGCCCGTAGGCCGCGCGGCTTCTCTCCTGTACAGACCGTCGGGACGCTGGCGGCACGATGG
CCACAAGGGAGGTGTCGATT

Downstream 100 bases:

>100_bases
GCGCGGGTCGTCGGGTTGAGGAGGGTGCGGCGCTCGCCCCGTTAGTCCACCCGGCCGTCGCCTGACGATCAGCCGATCAT
CCGCTCCAAGACGCGCATCC

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 443; Mature: 443

Protein sequence:

>443_residues
MDDGWATALGLFAVLALVLANGFFVAAEFALVAVRRSRVAELVAERRVNAKALLWATDHLDAHLAATQLGITISSLALGW
VGEPALAHLILPALTWLPDMLSTAAAHTVAVVISFVIITALHIVLGELAPKSLALQRSERTALAVIRPLSVFLFVFRPAI
LFLNGLGNGVLRLCGLQPGHGEGGHHSTAELNLLVEASREAGLIREAQQEAVERIFRLGDRRVREIMTPRHEVEWVDLDG
SPEEITRAVRACSHAHVLVSRGGIDEVVGVLRKQDLLDQILDGQPLDIAAAMRPPNVVHEGMTVLTALESFQRNPVQLAV
IVDEYGSLEGLVTQTDLLEAIAGDIPEIGEDPAVVEREDGSLLIDGMMPAEDAFERLAFTDPPDTDDYTTLAGYVIFQLG
RIPAAGDALVAEGWRLEVVDMDGRRIDKVLATRLPGRALTGTA

Sequences:

>Translated_443_residues
MDDGWATALGLFAVLALVLANGFFVAAEFALVAVRRSRVAELVAERRVNAKALLWATDHLDAHLAATQLGITISSLALGW
VGEPALAHLILPALTWLPDMLSTAAAHTVAVVISFVIITALHIVLGELAPKSLALQRSERTALAVIRPLSVFLFVFRPAI
LFLNGLGNGVLRLCGLQPGHGEGGHHSTAELNLLVEASREAGLIREAQQEAVERIFRLGDRRVREIMTPRHEVEWVDLDG
SPEEITRAVRACSHAHVLVSRGGIDEVVGVLRKQDLLDQILDGQPLDIAAAMRPPNVVHEGMTVLTALESFQRNPVQLAV
IVDEYGSLEGLVTQTDLLEAIAGDIPEIGEDPAVVEREDGSLLIDGMMPAEDAFERLAFTDPPDTDDYTTLAGYVIFQLG
RIPAAGDALVAEGWRLEVVDMDGRRIDKVLATRLPGRALTGTA
>Mature_443_residues
MDDGWATALGLFAVLALVLANGFFVAAEFALVAVRRSRVAELVAERRVNAKALLWATDHLDAHLAATQLGITISSLALGW
VGEPALAHLILPALTWLPDMLSTAAAHTVAVVISFVIITALHIVLGELAPKSLALQRSERTALAVIRPLSVFLFVFRPAI
LFLNGLGNGVLRLCGLQPGHGEGGHHSTAELNLLVEASREAGLIREAQQEAVERIFRLGDRRVREIMTPRHEVEWVDLDG
SPEEITRAVRACSHAHVLVSRGGIDEVVGVLRKQDLLDQILDGQPLDIAAAMRPPNVVHEGMTVLTALESFQRNPVQLAV
IVDEYGSLEGLVTQTDLLEAIAGDIPEIGEDPAVVEREDGSLLIDGMMPAEDAFERLAFTDPPDTDDYTTLAGYVIFQLG
RIPAAGDALVAEGWRLEVVDMDGRRIDKVLATRLPGRALTGTA

Specific function: Unknown

COG id: COG1253

COG function: function code R; Hemolysins and related proteins containing CBS domains

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 CBS domains [H]

Homologues:

Organism=Homo sapiens, GI310128564, Length=378, Percent_Identity=32.010582010582, Blast_Score=208, Evalue=8e-54,
Organism=Escherichia coli, GI1790664, Length=432, Percent_Identity=29.6296296296296, Blast_Score=224, Evalue=7e-60,
Organism=Escherichia coli, GI87082033, Length=267, Percent_Identity=32.2097378277154, Blast_Score=134, Evalue=1e-32,
Organism=Escherichia coli, GI145693175, Length=330, Percent_Identity=26.0606060606061, Blast_Score=115, Evalue=4e-27,
Organism=Escherichia coli, GI1788119, Length=233, Percent_Identity=31.7596566523605, Blast_Score=108, Evalue=7e-25,
Organism=Escherichia coli, GI1786879, Length=266, Percent_Identity=27.0676691729323, Blast_Score=81, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR016169
- InterPro:   IPR000644
- InterPro:   IPR002550
- InterPro:   IPR005170 [H]

Pfam domain/function: PF00571 CBS; PF03471 CorC_HlyC; PF01595 DUF21 [H]

EC number: NA

Molecular weight: Translated: 47734; Mature: 47734

Theoretical pI: Translated: 4.61; Mature: 4.61

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDDGWATALGLFAVLALVLANGFFVAAEFALVAVRRSRVAELVAERRVNAKALLWATDHL
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
DAHLAATQLGITISSLALGWVGEPALAHLILPALTWLPDMLSTAAAHTVAVVISFVIITA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHIVLGELAPKSLALQRSERTALAVIRPLSVFLFVFRPAILFLNGLGNGVLRLCGLQPGH
HHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
GEGGHHSTAELNLLVEASREAGLIREAQQEAVERIFRLGDRRVREIMTPRHEVEWVDLDG
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
SPEEITRAVRACSHAHVLVSRGGIDEVVGVLRKQDLLDQILDGQPLDIAAAMRPPNVVHE
CHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHH
GMTVLTALESFQRNPVQLAVIVDEYGSLEGLVTQTDLLEAIAGDIPEIGEDPAVVEREDG
HHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
SLLIDGMMPAEDAFERLAFTDPPDTDDYTTLAGYVIFQLGRIPAAGDALVAEGWRLEVVD
CEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHEECCCEEEEEE
MDGRRIDKVLATRLPGRALTGTA
CCCHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure
MDDGWATALGLFAVLALVLANGFFVAAEFALVAVRRSRVAELVAERRVNAKALLWATDHL
CCCHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCC
DAHLAATQLGITISSLALGWVGEPALAHLILPALTWLPDMLSTAAAHTVAVVISFVIITA
HHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LHIVLGELAPKSLALQRSERTALAVIRPLSVFLFVFRPAILFLNGLGNGVLRLCGLQPGH
HHHHHHHCCCHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHCCCCCC
GEGGHHSTAELNLLVEASREAGLIREAQQEAVERIFRLGDRRVREIMTPRHEVEWVDLDG
CCCCCCCCCEEEEEEECCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEEECCC
SPEEITRAVRACSHAHVLVSRGGIDEVVGVLRKQDLLDQILDGQPLDIAAAMRPPNVVHE
CHHHHHHHHHHHHHHEEEEECCCHHHHHHHHHHHHHHHHHHCCCCCEEEECCCCCHHHHH
GMTVLTALESFQRNPVQLAVIVDEYGSLEGLVTQTDLLEAIAGDIPEIGEDPAVVEREDG
HHHHHHHHHHHCCCCEEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCCEEEECCC
SLLIDGMMPAEDAFERLAFTDPPDTDDYTTLAGYVIFQLGRIPAAGDALVAEGWRLEVVD
CEEEECCCCHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHCCCCCCCCHHEECCCEEEEEE
MDGRRIDKVLATRLPGRALTGTA
CCCHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905231 [H]