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The map label for this gene is kdpE [H]

Identifier: 170746653

GI number: 170746653

Start: 211617

End: 212345

Strand: Reverse

Name: kdpE [H]

Synonym: Mrad2831_0204

Alternate gene names: 170746653

Gene position: 212345-211617 (Counterclockwise)

Preceding gene: 170746654

Following gene: 170746652

Centisome position: 3.49

GC content: 72.7

Gene sequence:

>729_bases
ATGAGCCCCGCCGTCCTGGTCGTCGACGACGAGCCGCCGATCCGCAAGCTCCTGCGCATGGGCCTGGCCACCCAGGGCTA
CGCCGTCCTGGAGGCGCCCGATGCGCGAACCGCCCTGGCGCTGCTCGGCCGCGAGGGGGTGGATCTCGTCATCCTCGACC
TCGGACTGCCCGACATGCGCGGCCACGACCTGCTGCGGTCGGTGCGGGCGAGCCATCCGGACCTCCCCGTGGTCGTCCTG
TCGAGCCGCGACGACGAGGGCGGCAAGGTCGAGGCGCTCGATCTCGGCGCCAACGACTACGTGACCAAGCCGTTCGGCAT
GGCGGAGCTGCTGGCGCGCCTGCGGGCCGCCATGCGACACCAGCTCGCCGCGCGGGGCGAGCGGCCGATCTTCCGCGTCG
ACAACCTGTCGGTCGATCTGGTCCGCCGGATCGTGAAGGTCGACGAGGCCGAGGTGAAGCTCACGCCGCGCGAGTACGAC
TTCCTGCGCGTCCTGGTCCTGCACGCCGGCAAGGTGCTGACCCACGCGCAGCTGATGCGCTCCGTGCCGTCCTCGTCCGA
CCCGCAATACCTGCGCGTCTACGTGCGCCAGCTCCGCCAGAAGCTGGAGGCGGATCCCGAGCGGCCGCGGATCTTGCTGA
CCGAGACCGGCGTCGGCTACCGCCTGCGCGCGCCGGACGACGAGCCGGCCCCGCATTCCCGCGGCGCCGACGGCGCGACC
GCCCCCTGA

Upstream 100 bases:

>100_bases
GCGGCACCGTCACGGCCGAGAATCGCCGCGACCGCGGCGGGGCCTGCTTCACCGTGAGCCTGCCGGTTCCGGCCCGGAAT
GCACCCAGGGACATCGCCGC

Downstream 100 bases:

>100_bases
TTCCGAGGACGAGTTGATGCTTCGCAGCGCCCGCGATCCCGCGCGATGACGATAGATCGGATCCTCGCGCCCGCCGACGT
ACTCGTCGGCCTGCGCGCCG

Product: two component transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 242; Mature: 241

Protein sequence:

>242_residues
MSPAVLVVDDEPPIRKLLRMGLATQGYAVLEAPDARTALALLGREGVDLVILDLGLPDMRGHDLLRSVRASHPDLPVVVL
SSRDDEGGKVEALDLGANDYVTKPFGMAELLARLRAAMRHQLAARGERPIFRVDNLSVDLVRRIVKVDEAEVKLTPREYD
FLRVLVLHAGKVLTHAQLMRSVPSSSDPQYLRVYVRQLRQKLEADPERPRILLTETGVGYRLRAPDDEPAPHSRGADGAT
AP

Sequences:

>Translated_242_residues
MSPAVLVVDDEPPIRKLLRMGLATQGYAVLEAPDARTALALLGREGVDLVILDLGLPDMRGHDLLRSVRASHPDLPVVVL
SSRDDEGGKVEALDLGANDYVTKPFGMAELLARLRAAMRHQLAARGERPIFRVDNLSVDLVRRIVKVDEAEVKLTPREYD
FLRVLVLHAGKVLTHAQLMRSVPSSSDPQYLRVYVRQLRQKLEADPERPRILLTETGVGYRLRAPDDEPAPHSRGADGAT
AP
>Mature_241_residues
SPAVLVVDDEPPIRKLLRMGLATQGYAVLEAPDARTALALLGREGVDLVILDLGLPDMRGHDLLRSVRASHPDLPVVVLS
SRDDEGGKVEALDLGANDYVTKPFGMAELLARLRAAMRHQLAARGERPIFRVDNLSVDLVRRIVKVDEAEVKLTPREYDF
LRVLVLHAGKVLTHAQLMRSVPSSSDPQYLRVYVRQLRQKLEADPERPRILLTETGVGYRLRAPDDEPAPHSRGADGATA
P

Specific function: Member of the two-component regulatory system kdpD/kdpE involved in the regulation of the kdp operon [H]

COG id: COG0745

COG function: function code TK; Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain

Gene ontology:

Cell location: Cytoplasmic [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI1786911, Length=221, Percent_Identity=46.606334841629, Blast_Score=183, Evalue=1e-47,
Organism=Escherichia coli, GI1786784, Length=227, Percent_Identity=35.6828193832599, Blast_Score=128, Evalue=3e-31,
Organism=Escherichia coli, GI1787375, Length=220, Percent_Identity=35, Blast_Score=116, Evalue=1e-27,
Organism=Escherichia coli, GI87082012, Length=223, Percent_Identity=32.2869955156951, Blast_Score=115, Evalue=3e-27,
Organism=Escherichia coli, GI1786599, Length=227, Percent_Identity=31.7180616740088, Blast_Score=114, Evalue=7e-27,
Organism=Escherichia coli, GI1790552, Length=227, Percent_Identity=35.2422907488987, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1789809, Length=224, Percent_Identity=32.5892857142857, Blast_Score=110, Evalue=6e-26,
Organism=Escherichia coli, GI1790860, Length=224, Percent_Identity=32.1428571428571, Blast_Score=106, Evalue=2e-24,
Organism=Escherichia coli, GI1789402, Length=221, Percent_Identity=33.0316742081448, Blast_Score=102, Evalue=2e-23,
Organism=Escherichia coli, GI1790863, Length=231, Percent_Identity=29.004329004329, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1787229, Length=233, Percent_Identity=29.1845493562232, Blast_Score=101, Evalue=5e-23,
Organism=Escherichia coli, GI1788394, Length=229, Percent_Identity=28.3842794759825, Blast_Score=86, Evalue=3e-18,
Organism=Escherichia coli, GI2367329, Length=207, Percent_Identity=31.4009661835749, Blast_Score=80, Evalue=9e-17,
Organism=Escherichia coli, GI1788550, Length=117, Percent_Identity=35.8974358974359, Blast_Score=78, Evalue=7e-16,
Organism=Escherichia coli, GI1790299, Length=116, Percent_Identity=33.6206896551724, Blast_Score=70, Evalue=1e-13,
Organism=Escherichia coli, GI145693140, Length=243, Percent_Identity=25.9259259259259, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI1790437, Length=125, Percent_Identity=33.6, Blast_Score=68, Evalue=7e-13,
Organism=Escherichia coli, GI1788905, Length=124, Percent_Identity=33.8709677419355, Blast_Score=62, Evalue=4e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR011006
- InterPro:   IPR001867
- InterPro:   IPR001789
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00072 Response_reg; PF00486 Trans_reg_C [H]

EC number: NA

Molecular weight: Translated: 26707; Mature: 26576

Theoretical pI: Translated: 7.19; Mature: 7.19

Prosite motif: PS50110 RESPONSE_REGULATORY

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSPAVLVVDDEPPIRKLLRMGLATQGYAVLEAPDARTALALLGREGVDLVILDLGLPDMR
CCCCEEEECCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCC
GHDLLRSVRASHPDLPVVVLSSRDDEGGKVEALDLGANDYVTKPFGMAELLARLRAAMRH
HHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
QLAARGERPIFRVDNLSVDLVRRIVKVDEAEVKLTPREYDFLRVLVLHAGKVLTHAQLMR
HHHHCCCCCEEEECCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCHHHHHHHHHH
SVPSSSDPQYLRVYVRQLRQKLEADPERPRILLTETGVGYRLRAPDDEPAPHSRGADGAT
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCC
AP
CC
>Mature Secondary Structure 
SPAVLVVDDEPPIRKLLRMGLATQGYAVLEAPDARTALALLGREGVDLVILDLGLPDMR
CCCEEEECCCCHHHHHHHHCCCCCCEEEEECCCHHHHHHHHCCCCCEEEEEECCCCCCC
GHDLLRSVRASHPDLPVVVLSSRDDEGGKVEALDLGANDYVTKPFGMAELLARLRAAMRH
HHHHHHHHHHCCCCCCEEEEECCCCCCCEEEEEEECCCCCCCCCCCHHHHHHHHHHHHHH
QLAARGERPIFRVDNLSVDLVRRIVKVDEAEVKLTPREYDFLRVLVLHAGKVLTHAQLMR
HHHHCCCCCEEEECCCCHHHHHHHHHCCCCEEEECCCHHHHHHHHHHHHCHHHHHHHHHH
SVPSSSDPQYLRVYVRQLRQKLEADPERPRILLTETGVGYRLRAPDDEPAPHSRGADGAT
HCCCCCCHHHHHHHHHHHHHHHHCCCCCCEEEEEECCCCEEEECCCCCCCCCCCCCCCCC
AP
CC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 1532388; 8905232; 9278503 [H]