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The map label for this gene is exoP [H]

Identifier: 170746630

GI number: 170746630

Start: 179732

End: 181927

Strand: Reverse

Name: exoP [H]

Synonym: Mrad2831_0181

Alternate gene names: 170746630

Gene position: 181927-179732 (Counterclockwise)

Preceding gene: 170746631

Following gene: 170746629

Centisome position: 2.99

GC content: 72.45

Gene sequence:

>2196_bases
ATGTCCTTCCTGACTGTCGATCTGGCCGACCGGGCGCCGGTCCGGGCCCTCCCCCAGGAGCCGGCGCGCGGCGGTCCGCT
GGCCGCCGCCCTCGCGCGGATCTGGCATCGCCGGACCCTGTTCCTGGCGGTGTTCGCCGCGGTCCTCGGCCTCGCCGTCA
CCGCGCTGCTGATGATCCAGCCGCAATACGTGGCGAGCGGCTCGGTGATCGTCGCCGAGGCCGAGCCGGGCGCCAACAAC
GCCTCGATGGCCTGGATCCAGAAGATCGGCGACCCGGCGGACATCGAGAGCCAGATCCTGGTGATCCGCTCGCCACGGCT
CCTGCGCCTCGCCATCGACGACAACCTCGTCGCCGCGGTCCTCGCCGAGTGCCGCTACGCGGCGACCGGCGGTCATCCCG
ACCGGATCAGCGACAAGAAGGACGCCGCCTGCACGAAGCTCACGACCGACCGCAACGCGCTCGTCGAGTATCTGCAGAGG
CGCTACACGGTCCTGAGCTCCGGCCGCTCGCGCATCATCACCATCGGCTACAAGTCGCCGCTGCCCGAGACGGCGCAGAC
CATGGCCAACGGCCTGATCAACGCCTTCCTGGAAGACCAGCGCGAGGCGCAGGCCTCGAGCCGCAAGGCGGCGGCCGACT
GGCTGCACACCGAGATTAGCCAGCTGGACGCGTCGATCCGGGCCGACGAGACCCGCATCCAAACGTTCCGGCGCCGCAAG
GGCCTGCTGAAGGGCTCGCTGGCCCCGATCAGCGCCGAGCGGCTCACCAGCATCAGCCAGCAGCTCGCCGCGGCCGAGAC
CGCCAAAGCGGACGCCGCCGCGCGGCTGAGCGAGATCGAGGCCAGGGGCACCCGCGGCGCCGACAGCGCCCCGGCCGTCC
TGGCGAGCCCGACCATCGTCTCGCTGAAGCAGCAGCTCAGCGGTGTCAGCGCGCAGCTCGCCAACCAGAGCACCCTGCTG
GGCGCGAACCATCCGGTCATCCGGGCGCTCGAGACCGAGCAGGCGAGCCTGCGCGCGCGGATCGAGCAGGAGATCGGGAA
CGTCGCGCGGGGCCTGCGCAAGTCCTACGAGGCCTCGAGCACCCTCGCCAAGTCGCTGCGCGCCCAACTCGAGACCGCGA
AGACGGACGCCGCCGCCGCCATGGACGACGAGGCCTCGATCGAGGGCATGGTGCGCAACGCCGAGATCAAGCGCACCCGC
TACGCCGATCTGGTGAAGCGCGCGGGCGAGCTCGAGACCGAGCGGCGGATCCTGACCGGCAGCACGCGGCTGGTCAGCCT
CGCCGAGTTGCCGCAGGAGCCGTTCTCGCCCAAGGCCGTGCCGTTCCTGGCGGGCGGCCTCGTGCTCGCCGGCGTGCTCG
CCGCCGCCGCCGCGCTGCTGCGCGACTACACCGACCGGCGCGTGCGCACCTCGGCGCAGCTGATGGCGGGCACCGGCGCA
CCGGTCTTCGCGCAATTGCCGAGCCTGGAGACCGCCGGCCTCGTCGGCCGCTTCTCCGAGCGCCAGCGCGAGCTCGACCT
CGCGGAGGCCCTGGCGCGGGCGCGGGTTTATCCGGTGATGCAGAACGTCCTGCGCAACCTGCACGCCCATCTCGTGCTGG
CCGGCGCCGGCAAGTCCCGCGTCATCCTGGTCACCTCGGCGAAGCCGCGGGAGGGCAAATCCTTCACGGCCTTCGCGCTC
GCCGGGATCGGCGCCGCAAGCGGCCGACGGGTGCTCGTGGTCGAGTGCGACCTGCGGCGCCCGAACTTCGAGGCCTCCCT
CGGGCTCGGCCGCGGCGCGGGCCTCGGCGGCGTGCTCCGCGGCGAGATCGACCCGGCCGAGGCCGTTGTCCGGGCCGGAC
GCTTCGACGTCATCCCCGCGGGAACGCCGACGGCCGACTCGACCGAGCTCCTGATGGGCGACCGGATGGCGGACTTCCTC
AAGTGGAGCCGCCGCTACGACCTCGTCCTCCTCGACACGCCGCCCACGAGTCTCCTGATGGACGCGCCGATGCTCGCCCG
CCAGGTCGACGGCGTGCTCTGCTGCGCCCGCTACGGCCGCTCGCAGCTCTCCGACACCGTCGAGACCGTGGCGAACCTGC
GCCGCGCCGGCGGACACGTCCTCGGGATCGCCATGACCATGGTCCGCCCGGGTATCCAGTCGACCTACGACGTGATGCCG
CTTCCCGATCCCCGGGCGGCCGCGAGCGCGCGATGA

Upstream 100 bases:

>100_bases
CGAACTTCGTCGATGACCAGATGGCCCTGCACCGGGCCGCCTGCGAGACGCGCCCGCGGATCGTGCCGCGCCTCGAAGCC
GTCGGCTGAGGGCAGATCGC

Downstream 100 bases:

>100_bases
ACGACGTGCTTCCCGCCGAAGCGCTCGCCGAGCGCGGCCTCCTTGACCGGGTGCGGGCCACCCGCTCCGACGTCGCCGCT
CGGCCGCGCGTCCTGTTCGT

Product: non-specific protein-tyrosine kinase

Products: ADP; protein tyrosine phosphate [C]

Alternate protein names: NA

Number of amino acids: Translated: 731; Mature: 730

Protein sequence:

>731_residues
MSFLTVDLADRAPVRALPQEPARGGPLAAALARIWHRRTLFLAVFAAVLGLAVTALLMIQPQYVASGSVIVAEAEPGANN
ASMAWIQKIGDPADIESQILVIRSPRLLRLAIDDNLVAAVLAECRYAATGGHPDRISDKKDAACTKLTTDRNALVEYLQR
RYTVLSSGRSRIITIGYKSPLPETAQTMANGLINAFLEDQREAQASSRKAAADWLHTEISQLDASIRADETRIQTFRRRK
GLLKGSLAPISAERLTSISQQLAAAETAKADAAARLSEIEARGTRGADSAPAVLASPTIVSLKQQLSGVSAQLANQSTLL
GANHPVIRALETEQASLRARIEQEIGNVARGLRKSYEASSTLAKSLRAQLETAKTDAAAAMDDEASIEGMVRNAEIKRTR
YADLVKRAGELETERRILTGSTRLVSLAELPQEPFSPKAVPFLAGGLVLAGVLAAAAALLRDYTDRRVRTSAQLMAGTGA
PVFAQLPSLETAGLVGRFSERQRELDLAEALARARVYPVMQNVLRNLHAHLVLAGAGKSRVILVTSAKPREGKSFTAFAL
AGIGAASGRRVLVVECDLRRPNFEASLGLGRGAGLGGVLRGEIDPAEAVVRAGRFDVIPAGTPTADSTELLMGDRMADFL
KWSRRYDLVLLDTPPTSLLMDAPMLARQVDGVLCCARYGRSQLSDTVETVANLRRAGGHVLGIAMTMVRPGIQSTYDVMP
LPDPRAAASAR

Sequences:

>Translated_731_residues
MSFLTVDLADRAPVRALPQEPARGGPLAAALARIWHRRTLFLAVFAAVLGLAVTALLMIQPQYVASGSVIVAEAEPGANN
ASMAWIQKIGDPADIESQILVIRSPRLLRLAIDDNLVAAVLAECRYAATGGHPDRISDKKDAACTKLTTDRNALVEYLQR
RYTVLSSGRSRIITIGYKSPLPETAQTMANGLINAFLEDQREAQASSRKAAADWLHTEISQLDASIRADETRIQTFRRRK
GLLKGSLAPISAERLTSISQQLAAAETAKADAAARLSEIEARGTRGADSAPAVLASPTIVSLKQQLSGVSAQLANQSTLL
GANHPVIRALETEQASLRARIEQEIGNVARGLRKSYEASSTLAKSLRAQLETAKTDAAAAMDDEASIEGMVRNAEIKRTR
YADLVKRAGELETERRILTGSTRLVSLAELPQEPFSPKAVPFLAGGLVLAGVLAAAAALLRDYTDRRVRTSAQLMAGTGA
PVFAQLPSLETAGLVGRFSERQRELDLAEALARARVYPVMQNVLRNLHAHLVLAGAGKSRVILVTSAKPREGKSFTAFAL
AGIGAASGRRVLVVECDLRRPNFEASLGLGRGAGLGGVLRGEIDPAEAVVRAGRFDVIPAGTPTADSTELLMGDRMADFL
KWSRRYDLVLLDTPPTSLLMDAPMLARQVDGVLCCARYGRSQLSDTVETVANLRRAGGHVLGIAMTMVRPGIQSTYDVMP
LPDPRAAASAR
>Mature_730_residues
SFLTVDLADRAPVRALPQEPARGGPLAAALARIWHRRTLFLAVFAAVLGLAVTALLMIQPQYVASGSVIVAEAEPGANNA
SMAWIQKIGDPADIESQILVIRSPRLLRLAIDDNLVAAVLAECRYAATGGHPDRISDKKDAACTKLTTDRNALVEYLQRR
YTVLSSGRSRIITIGYKSPLPETAQTMANGLINAFLEDQREAQASSRKAAADWLHTEISQLDASIRADETRIQTFRRRKG
LLKGSLAPISAERLTSISQQLAAAETAKADAAARLSEIEARGTRGADSAPAVLASPTIVSLKQQLSGVSAQLANQSTLLG
ANHPVIRALETEQASLRARIEQEIGNVARGLRKSYEASSTLAKSLRAQLETAKTDAAAAMDDEASIEGMVRNAEIKRTRY
ADLVKRAGELETERRILTGSTRLVSLAELPQEPFSPKAVPFLAGGLVLAGVLAAAAALLRDYTDRRVRTSAQLMAGTGAP
VFAQLPSLETAGLVGRFSERQRELDLAEALARARVYPVMQNVLRNLHAHLVLAGAGKSRVILVTSAKPREGKSFTAFALA
GIGAASGRRVLVVECDLRRPNFEASLGLGRGAGLGGVLRGEIDPAEAVVRAGRFDVIPAGTPTADSTELLMGDRMADFLK
WSRRYDLVLLDTPPTSLLMDAPMLARQVDGVLCCARYGRSQLSDTVETVANLRRAGGHVLGIAMTMVRPGIQSTYDVMPL
PDPRAAASAR

Specific function: Required For The Extracellular Polysaccharide Colanic Acid Synthesis. The Autophosphorylated Form Is Inactive. Probably Involved In The Export Of Colanic Acid From The Cell To Medium. [C]

COG id: COG3206

COG function: function code M; Uncharacterized protein involved in exopolysaccharide biosynthesis

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Probable) [H]

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: To B.solanacearum epsB [H]

Homologues:

Organism=Escherichia coli, GI87082032, Length=444, Percent_Identity=26.3513513513513, Blast_Score=131, Evalue=2e-31,
Organism=Escherichia coli, GI1787216, Length=427, Percent_Identity=28.1030444964871, Blast_Score=122, Evalue=1e-28,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002586
- InterPro:   IPR005702
- InterPro:   IPR005700
- InterPro:   IPR003856 [H]

Pfam domain/function: PF01656 CbiA; PF02706 Wzz [H]

EC number: 2.7.1.112 [C]

Molecular weight: Translated: 78135; Mature: 78004

Theoretical pI: Translated: 10.07; Mature: 10.07

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
2.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFLTVDLADRAPVRALPQEPARGGPLAAALARIWHRRTLFLAVFAAVLGLAVTALLMIQ
CCEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PQYVASGSVIVAEAEPGANNASMAWIQKIGDPADIESQILVIRSPRLLRLAIDDNLVAAV
CHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCHHHHHH
LAECRYAATGGHPDRISDKKDAACTKLTTDRNALVEYLQRRYTVLSSGRSRIITIGYKSP
HHHHHHHCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
LPETAQTMANGLINAFLEDQREAQASSRKAAADWLHTEISQLDASIRADETRIQTFRRRK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GLLKGSLAPISAERLTSISQQLAAAETAKADAAARLSEIEARGTRGADSAPAVLASPTIV
CHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHH
SLKQQLSGVSAQLANQSTLLGANHPVIRALETEQASLRARIEQEIGNVARGLRKSYEASS
HHHHHHCCHHHHHCCCCEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLAKSLRAQLETAKTDAAAAMDDEASIEGMVRNAEIKRTRYADLVKRAGELETERRILTG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHCEEECC
STRLVSLAELPQEPFSPKAVPFLAGGLVLAGVLAAAAALLRDYTDRRVRTSAQLMAGTGA
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVFAQLPSLETAGLVGRFSERQRELDLAEALARARVYPVMQNVLRNLHAHLVLAGAGKSR
CHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCE
VILVTSAKPREGKSFTAFALAGIGAASGRRVLVVECDLRRPNFEASLGLGRGAGLGGVLR
EEEEECCCCCCCCCEEEHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEE
GEIDPAEAVVRAGRFDVIPAGTPTADSTELLMGDRMADFLKWSRRYDLVLLDTPPTSLLM
CCCCHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHH
DAPMLARQVDGVLCCARYGRSQLSDTVETVANLRRAGGHVLGIAMTMVRPGIQSTYDVMP
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCC
LPDPRAAASAR
CCCCCCCCCCC
>Mature Secondary Structure 
SFLTVDLADRAPVRALPQEPARGGPLAAALARIWHRRTLFLAVFAAVLGLAVTALLMIQ
CEEEEECCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
PQYVASGSVIVAEAEPGANNASMAWIQKIGDPADIESQILVIRSPRLLRLAIDDNLVAAV
CHHCCCCCEEEEECCCCCCCCHHHHHHHCCCCCCCCCCEEEEECCCEEEEEECCHHHHHH
LAECRYAATGGHPDRISDKKDAACTKLTTDRNALVEYLQRRYTVLSSGRSRIITIGYKSP
HHHHHHHCCCCCCCCCCCCCCHHHHHCCCCHHHHHHHHHHHHHHHHCCCCEEEEEECCCC
LPETAQTMANGLINAFLEDQREAQASSRKAAADWLHTEISQLDASIRADETRIQTFRRRK
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHH
GLLKGSLAPISAERLTSISQQLAAAETAKADAAARLSEIEARGTRGADSAPAVLASPTIV
CHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCCHHH
SLKQQLSGVSAQLANQSTLLGANHPVIRALETEQASLRARIEQEIGNVARGLRKSYEASS
HHHHHHCCHHHHHCCCCEEECCCCCEEEEECHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
TLAKSLRAQLETAKTDAAAAMDDEASIEGMVRNAEIKRTRYADLVKRAGELETERRILTG
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHCCHHHHHHHHHHHHHHCCHHHHCEEECC
STRLVSLAELPQEPFSPKAVPFLAGGLVLAGVLAAAAALLRDYTDRRVRTSAQLMAGTGA
CHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
PVFAQLPSLETAGLVGRFSERQRELDLAEALARARVYPVMQNVLRNLHAHLVLAGAGKSR
CHHHCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEEEECCCCE
VILVTSAKPREGKSFTAFALAGIGAASGRRVLVVECDLRRPNFEASLGLGRGAGLGGVLR
EEEEECCCCCCCCCEEEHHHHHCCCCCCCEEEEEEECCCCCCCCCCCCCCCCCCCCCEEE
GEIDPAEAVVRAGRFDVIPAGTPTADSTELLMGDRMADFLKWSRRYDLVLLDTPPTSLLM
CCCCHHHHHHHCCCEEEECCCCCCCCCHHHHHHHHHHHHHHHHCCCCEEEECCCCHHHHH
DAPMLARQVDGVLCCARYGRSQLSDTVETVANLRRAGGHVLGIAMTMVRPGIQSTYDVMP
CCHHHHHHHHHHHHHHHHCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCC
LPDPRAAASAR
CCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: ATP; a protein tyrosine [C]

Specific reaction: ATP + a protein tyrosine = ADP + protein tyrosine phosphate [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8226645; 8226646; 8246891; 11481431 [H]