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The map label for this gene is ctaC [H]

Identifier: 170746483

GI number: 170746483

Start: 34731

End: 35570

Strand: Reverse

Name: ctaC [H]

Synonym: Mrad2831_0033

Alternate gene names: 170746483

Gene position: 35570-34731 (Counterclockwise)

Preceding gene: 170746485

Following gene: 170746482

Centisome position: 0.59

GC content: 65.95

Gene sequence:

>840_bases
ATGCGGACGGTGCGGACGATCAACCGGTCACTCTGGAGCCTCGCCGCTCTCGGCGCCCTGCTCTTCCCGATATCCGGCGC
GCAGGCCGCGGGCTTCGGTCAGCCCGTGCCGTGGGAGATGGACCGGCAGATCCCGGTCACCGAGAACGCGCGCGACATCC
TGAACTTCGAGATCGGACTGCACTGGCTGTCCCTTGCCATCTCGGTCTTCGTCCTCGGACTCATCCTCTGGTGCGTCTAC
CGCTTCGGCGAGAAGCGGAACCCGACGCCCTCGCGGACCACGCACAACACCGCCATCGAGATCGCCTGGACGATCGTGCC
GGTGCTGATCCTAGTCGCCGTGGCGATCCCGTCCTTCCGCCTGCTGCGCACGCAGCTCTCGGATCCGAAGGCCGACATGA
TCGTCAAGGTCATCGGCCATGCCTGGTACTGGTCGTACGAGTACCCGCAGACGGAGGCCGGCGGCGGCTTCACGTTCGAT
GCCAACCTCGACGAGGACAAGCAGCCGCGCCTGCTCCAGACCGACAACGAGATGGTCGTTCCGGTCAACAAGATCGTGAA
GATCCAGGTCACCGCCGCCGACGTGCTGCATTCCTGGGCGATGCCGGCCTTCGGCTTCAAGATCGACGCCGTCCCAGGCC
GGCTGAACCAGATGTGGTTCAAGGCCGACAAGGAGGGCACGTTCCACGGCCAGTGCTCGGAGCTGTGCGGACAGCGCCAC
GCCTACATGCCGATCGTGGTTCGCGTGGTCAGCGAGCAGGCCTACGCCGACTGGCTGAAGGAGGCGAAGACCAAGTACGC
CCGCATCGACACCGGCACGAGCGTCGCCGAGGCGCGCTGA

Upstream 100 bases:

>100_bases
AACACAACCGGTACTCCGTCACGTCGGTACAATCCCGCACGCGGTCAAGACGGGAAGGTCCGGCGGCAGCCAGATAGTTC
AGGGGAGCCACGAGAGGCAG

Downstream 100 bases:

>100_bases
GCCCCGGCTGACCGACCCGAACCCATCAGATCCACAAGGCATCCGAATCCATGGCTACAGCCGCAGCCCATGCAGAGGCC
CACGAGGTCCACGACCATAA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 279; Mature: 279

Protein sequence:

>279_residues
MRTVRTINRSLWSLAALGALLFPISGAQAAGFGQPVPWEMDRQIPVTENARDILNFEIGLHWLSLAISVFVLGLILWCVY
RFGEKRNPTPSRTTHNTAIEIAWTIVPVLILVAVAIPSFRLLRTQLSDPKADMIVKVIGHAWYWSYEYPQTEAGGGFTFD
ANLDEDKQPRLLQTDNEMVVPVNKIVKIQVTAADVLHSWAMPAFGFKIDAVPGRLNQMWFKADKEGTFHGQCSELCGQRH
AYMPIVVRVVSEQAYADWLKEAKTKYARIDTGTSVAEAR

Sequences:

>Translated_279_residues
MRTVRTINRSLWSLAALGALLFPISGAQAAGFGQPVPWEMDRQIPVTENARDILNFEIGLHWLSLAISVFVLGLILWCVY
RFGEKRNPTPSRTTHNTAIEIAWTIVPVLILVAVAIPSFRLLRTQLSDPKADMIVKVIGHAWYWSYEYPQTEAGGGFTFD
ANLDEDKQPRLLQTDNEMVVPVNKIVKIQVTAADVLHSWAMPAFGFKIDAVPGRLNQMWFKADKEGTFHGQCSELCGQRH
AYMPIVVRVVSEQAYADWLKEAKTKYARIDTGTSVAEAR
>Mature_279_residues
MRTVRTINRSLWSLAALGALLFPISGAQAAGFGQPVPWEMDRQIPVTENARDILNFEIGLHWLSLAISVFVLGLILWCVY
RFGEKRNPTPSRTTHNTAIEIAWTIVPVLILVAVAIPSFRLLRTQLSDPKADMIVKVIGHAWYWSYEYPQTEAGGGFTFD
ANLDEDKQPRLLQTDNEMVVPVNKIVKIQVTAADVLHSWAMPAFGFKIDAVPGRLNQMWFKADKEGTFHGQCSELCGQRH
AYMPIVVRVVSEQAYADWLKEAKTKYARIDTGTSVAEAR

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=164, Percent_Identity=42.6829268292683, Blast_Score=152, Evalue=3e-37,
Organism=Saccharomyces cerevisiae, GI6226540, Length=237, Percent_Identity=40.084388185654, Blast_Score=167, Evalue=1e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 31329; Mature: 31329

Theoretical pI: Translated: 8.08; Mature: 8.08

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTVRTINRSLWSLAALGALLFPISGAQAAGFGQPVPWEMDRQIPVTENARDILNFEIGL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
HWLSLAISVFVLGLILWCVYRFGEKRNPTPSRTTHNTAIEIAWTIVPVLILVAVAIPSFR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
LLRTQLSDPKADMIVKVIGHAWYWSYEYPQTEAGGGFTFDANLDEDKQPRLLQTDNEMVV
HHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCEEEECCCCCCCCCCEEECCCCEEE
PVNKIVKIQVTAADVLHSWAMPAFGFKIDAVPGRLNQMWFKADKEGTFHGQCSELCGQRH
ECCCEEEEEEHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCHHHHHCCCCC
AYMPIVVRVVSEQAYADWLKEAKTKYARIDTGTSVAEAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCC
>Mature Secondary Structure
MRTVRTINRSLWSLAALGALLFPISGAQAAGFGQPVPWEMDRQIPVTENARDILNFEIGL
CCCHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHH
HWLSLAISVFVLGLILWCVYRFGEKRNPTPSRTTHNTAIEIAWTIVPVLILVAVAIPSFR
HHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHCCHHH
LLRTQLSDPKADMIVKVIGHAWYWSYEYPQTEAGGGFTFDANLDEDKQPRLLQTDNEMVV
HHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCCCEEEECCCCCCCCCCEEECCCCEEE
PVNKIVKIQVTAADVLHSWAMPAFGFKIDAVPGRLNQMWFKADKEGTFHGQCSELCGQRH
ECCCEEEEEEHHHHHHHHHCCCCCCEEEECCCCHHHHHHHCCCCCCCCCCHHHHHCCCCC
AYMPIVVRVVSEQAYADWLKEAKTKYARIDTGTSVAEAR
CHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 1648008 [H]