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The map label for this gene is hprK

Identifier: 170762340

GI number: 170762340

Start: 92929

End: 93855

Strand: Reverse

Name: hprK

Synonym: UPA3_0075

Alternate gene names: 170762340

Gene position: 93855-92929 (Counterclockwise)

Preceding gene: 170761927

Following gene: 170762410

Centisome position: 12.49

GC content: 26.75

Gene sequence:

>927_bases
ATGGAAATTCGTGGTAAATTATTTGTTAGTCAAGTTGTTAGAAAGTTTAATTTAAACGTTGTTGCAAATTCTGACTATAT
TGATCGTGAGATTTCTACAACAGGAATTACACGTGTTGGATTTGAATTAGCTGGCGAAATTTTGTTTAAAGAGATTTGAA
ATATTGTTTATTTTGGTTCAAAAGAAAGCAATTATTTTAATAAATTTTCAGAAACGATCATTTCTAAAAAATTAGGAAAA
ATTTTAGATTTAAATCCACCATTAATTATTTTTGGTAAAAATTTTAAACATGCTGGAATTTTGTTAAAATTAGCAGAGCG
CTATAAAATTCCAATTGTAGAGGTTAAATATAGTTTTTATGAATTAAATTTTACAATTAATAGTTACATTAGTCAAAAAC
TTTCACACCAATCATTAGTTCACGGAACATTATTATCTGTTTTTGGAATCGGCGTTATTTTAATGGGGGAATCAGGTGTT
GGTAAATCTGAGTTAGCAATTGAATTAGTTAAAAAAGGTCATATTTTTGTAGGTGATGATGCTATTTTAGTTAATAGAAT
TGGAGGTAATCTATATGGAAGAGCTGAAGATTCGACTAAAGATTTTATTGAAATTAGAGGTTTAGGTATTATGAATTTTT
CACGTTCTTTCGGTATTGAACGAATGATTGAATCAACAAAAATTGAAATAGTTATTGAATTAATAAAACCAGCTAAACAT
GAAAAAATCAAGTTTGAACGTTTTGGTCGTGAAATTCAACACAAAGAATTTTTAGAAACAAAAATAGCCCATTATTATAT
TCCGGTTATCGAAGGAAGAAGTATTTCAGATATCATTGAGACAGCCATTACTGATTATAAATTAAAAACATCAGGTTATA
ATTCAGCTGAAGAATTTATTTTACAAATTAATAAAAAGGGGATTTAA

Upstream 100 bases:

>100_bases
TTAGTTTAATATCATACAATAAAAGCGATAATATTAGCAACTCTAATGTTGATATTATCGATGATCATAATGTTATTGAG
AAATAGGTAGATAATAATTA

Downstream 100 bases:

>100_bases
ATGCAATTAGAAATTATTAATCCAGAAAGCACATTAGTTAATGATGTTGTTGCACATCGAGTAGCTTTTAGTATTGGTAG
CAATTTTAATATATATTGAT

Product: HPr kinase/phosphorylase

Products: NA

Alternate protein names: HPrK/P; HPr(Ser) kinase/phosphorylase [H]

Number of amino acids: Translated: 308; Mature: 308

Protein sequence:

>308_residues
MEIRGKLFVSQVVRKFNLNVVANSDYIDREISTTGITRVGFELAGEILFKEIWNIVYFGSKESNYFNKFSETIISKKLGK
ILDLNPPLIIFGKNFKHAGILLKLAERYKIPIVEVKYSFYELNFTINSYISQKLSHQSLVHGTLLSVFGIGVILMGESGV
GKSELAIELVKKGHIFVGDDAILVNRIGGNLYGRAEDSTKDFIEIRGLGIMNFSRSFGIERMIESTKIEIVIELIKPAKH
EKIKFERFGREIQHKEFLETKIAHYYIPVIEGRSISDIIETAITDYKLKTSGYNSAEEFILQINKKGI

Sequences:

>Translated_308_residues
MEIRGKLFVSQVVRKFNLNVVANSDYIDREISTTGITRVGFELAGEILFKEI*NIVYFGSKESNYFNKFSETIISKKLGK
ILDLNPPLIIFGKNFKHAGILLKLAERYKIPIVEVKYSFYELNFTINSYISQKLSHQSLVHGTLLSVFGIGVILMGESGV
GKSELAIELVKKGHIFVGDDAILVNRIGGNLYGRAEDSTKDFIEIRGLGIMNFSRSFGIERMIESTKIEIVIELIKPAKH
EKIKFERFGREIQHKEFLETKIAHYYIPVIEGRSISDIIETAITDYKLKTSGYNSAEEFILQINKKGI
>Mature_308_residues
MEIRGKLFVSQVVRKFNLNVVANSDYIDREISTTGITRVGFELAGEILFKEI*NIVYFGSKESNYFNKFSETIISKKLGK
ILDLNPPLIIFGKNFKHAGILLKLAERYKIPIVEVKYSFYELNFTINSYISQKLSHQSLVHGTLLSVFGIGVILMGESGV
GKSELAIELVKKGHIFVGDDAILVNRIGGNLYGRAEDSTKDFIEIRGLGIMNFSRSFGIERMIESTKIEIVIELIKPAKH
EKIKFERFGREIQHKEFLETKIAHYYIPVIEGRSISDIIETAITDYKLKTSGYNSAEEFILQINKKGI

Specific function: Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-pr

COG id: COG1493

COG function: function code T; Serine kinase of the HPr protein, regulates carbohydrate metabolism

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HPrK/P family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002078
- InterPro:   IPR003755
- InterPro:   IPR011104
- InterPro:   IPR011126 [H]

Pfam domain/function: PF07475 Hpr_kinase_C; PF02603 Hpr_kinase_N [H]

EC number: NA

Molecular weight: Translated: 34810; Mature: 34810

Theoretical pI: Translated: 9.54; Mature: 9.54

Prosite motif: PS00675 SIGMA54_INTERACT_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.3 %Met     (Translated Protein)
1.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEIRGKLFVSQVVRKFNLNVVANSDYIDREISTTGITRVGFELAGEILFKEINIVYFGSK
CCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCC
ESNYFNKFSETIISKKLGKILDLNPPLIIFGKNFKHAGILLKLAERYKIPIVEVKYSFYE
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHEEHHHHCCCEEEEEEEEEE
LNFTINSYISQKLSHQSLVHGTLLSVFGIGVILMGESGVGKSELAIELVKKGHIFVGDDA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHCCCEEECCCE
ILVNRIGGNLYGRAEDSTKDFIEIRGLGIMNFSRSFGIERMIESTKIEIVIELIKPAKHE
EEEEECCCCEEECCCCCCHHHHEEECCEEEECHHHCCHHHHHHHHHHHHHEEECCCCCCC
KIKFERFGREIQHKEFLETKIAHYYIPVIEGRSISDIIETAITDYKLKTSGYNSAEEFIL
CCHHHHHCHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHCEEEECCCCCHHHHHHE
QINKKGI
EECCCCC
>Mature Secondary Structure
MEIRGKLFVSQVVRKFNLNVVANSDYIDREISTTGITRVGFELAGEILFKEINIVYFGSK
CCCCHHHHHHHHHHHHCCEEEECCCCCCCCCCCCCHHHHHHHHHHHHHEEEEEEEEECCC
ESNYFNKFSETIISKKLGKILDLNPPLIIFGKNFKHAGILLKLAERYKIPIVEVKYSFYE
CCHHHHHHHHHHHHHHHHHHCCCCCCEEEEECCCCCHHHHHEEHHHHCCCEEEEEEEEEE
LNFTINSYISQKLSHQSLVHGTLLSVFGIGVILMGESGVGKSELAIELVKKGHIFVGDDA
EEEEHHHHHHHHHHHHHHHHHHHHHHHHCEEEEECCCCCCHHHHHHHHHHCCCEEECCCE
ILVNRIGGNLYGRAEDSTKDFIEIRGLGIMNFSRSFGIERMIESTKIEIVIELIKPAKHE
EEEEECCCCEEECCCCCCHHHHEEECCEEEECHHHCCHHHHHHHHHHHHHEEECCCCCCC
KIKFERFGREIQHKEFLETKIAHYYIPVIEGRSISDIIETAITDYKLKTSGYNSAEEFIL
CCHHHHHCHHHHHHHHHHHHHHHEEEEEECCCCHHHHHHHHHHCEEEECCCCCHHHHHHE
QINKKGI
EECCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11048724 [H]