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The map label for this gene is gph1 [H]

Identifier: 170762233

GI number: 170762233

Start: 150877

End: 151557

Strand: Direct

Name: gph1 [H]

Synonym: UPA3_0120

Alternate gene names: 170762233

Gene position: 150877-151557 (Clockwise)

Preceding gene: 170761955

Following gene: 170762388

Centisome position: 20.07

GC content: 24.67

Gene sequence:

>681_bases
ATGACCAAAAAACTGATTGTTTTTGATTTTGATGGTACAATTATGCACACGCATACAACTATGAGCCTATCTATTATTGG
TGTTTTAGAATTTTATAATCATCATATACCAAGTTTAAAAGAAATGAACGATCTGTTAGGTAATCTTTCTATGGTAAATA
TTTTTAAAAAGTATGCTAAACACGATCTTTTAAATATCGAAATTGAAATGATGATTTCTAAATATTATGAAATATATGAA
TCTTCGCTTTTTATGATCCATAGTTATTTTTTTGATGGTATTTTAGACCTAATCAAAAAATTAAAATCACTTAATAATAA
TGTTAAATTAGCAATTTTATCAAATAAACGATCTTCTTTATTAGCAACAATGGTTGATTATTATAATTTACGACCTTATT
TTGATTATATTTTTGGTGCTGAAGATGTCGAACAAATGAAGCCAGATCCTAGTGGTTTACTAAAAATTATGAACAACTGT
AATGTTGATCATAAAAATACTTTATTGATTGGTGATAGTATAGCTGATTTAAAAGCAGCTATAAATGCTAATTGTCATTT
TATTTTAGTTAATTGAGAACCACAATATCAAAAGCACATGGAAACAATTATTAATTTAAAACCTCTTATTGTTAAAACAA
TTGATGAACTAGAAACACAAATTAACCACTTTTTATATTAA

Upstream 100 bases:

>100_bases
ATGAAAGTTGATTATAATAATTTTAATTTAGATAAACAAGATGTTTATGATAATTTTATTGTTAATTATTATTCAAATAA
GAAGGAAAAATAAAAGATTT

Downstream 100 bases:

>100_bases
TGAACAAAAATGGCACAAAAAAGACTAGTTTATTATATAATATATAAGTGCTAGTTGCAGATGTAGTTCAATGGTAGAAC
GCAACCTTGCCAAGGTCGAG

Product: phosphoglycolate phosphatase

Products: NA

Alternate protein names: PGP 1; PGPase 1 [H]

Number of amino acids: Translated: 226; Mature: 225

Protein sequence:

>226_residues
MTKKLIVFDFDGTIMHTHTTMSLSIIGVLEFYNHHIPSLKEMNDLLGNLSMVNIFKKYAKHDLLNIEIEMMISKYYEIYE
SSLFMIHSYFFDGILDLIKKLKSLNNNVKLAILSNKRSSLLATMVDYYNLRPYFDYIFGAEDVEQMKPDPSGLLKIMNNC
NVDHKNTLLIGDSIADLKAAINANCHFILVNWEPQYQKHMETIINLKPLIVKTIDELETQINHFLY

Sequences:

>Translated_226_residues
MTKKLIVFDFDGTIMHTHTTMSLSIIGVLEFYNHHIPSLKEMNDLLGNLSMVNIFKKYAKHDLLNIEIEMMISKYYEIYE
SSLFMIHSYFFDGILDLIKKLKSLNNNVKLAILSNKRSSLLATMVDYYNLRPYFDYIFGAEDVEQMKPDPSGLLKIMNNC
NVDHKNTLLIGDSIADLKAAINANCHFILVN*EPQYQKHMETIINLKPLIVKTIDELETQINHFLY
>Mature_225_residues
TKKLIVFDFDGTIMHTHTTMSLSIIGVLEFYNHHIPSLKEMNDLLGNLSMVNIFKKYAKHDLLNIEIEMMISKYYEIYES
SLFMIHSYFFDGILDLIKKLKSLNNNVKLAILSNKRSSLLATMVDYYNLRPYFDYIFGAEDVEQMKPDPSGLLKIMNNCN
VDHKNTLLIGDSIADLKAAINANCHFILVN*EPQYQKHMETIINLKPLIVKTIDELETQINHFLY

Specific function: Specifically catalyzes the dephosphorylation of 2- phosphoglycolate. Is involved in the dissimilation of the intracellular 2-phosphoglycolate formed during the DNA repair of 3'-phosphoglycolate ends, a major class of DNA lesions induced by oxidative stres

COG id: COG0546

COG function: function code R; Predicted phosphatases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the HAD-like hydrolase superfamily. CbbY/CbbZ/Gph/YieH family [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005834
- InterPro:   IPR023214
- InterPro:   IPR006439
- InterPro:   IPR006402
- InterPro:   IPR005833
- InterPro:   IPR006346
- InterPro:   IPR023198 [H]

Pfam domain/function: PF00702 Hydrolase [H]

EC number: =3.1.3.18 [H]

Molecular weight: Translated: 26102; Mature: 25971

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
5.3 %Met     (Translated Protein)
6.2 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.9 %Met     (Mature Protein)
5.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTKKLIVFDFDGTIMHTHTTMSLSIIGVLEFYNHHIPSLKEMNDLLGNLSMVNIFKKYAK
CCCEEEEEECCCEEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHH
HDLLNIEIEMMISKYYEIYESSLFMIHSYFFDGILDLIKKLKSLNNNVKLAILSNKRSSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHH
LATMVDYYNLRPYFDYIFGAEDVEQMKPDPSGLLKIMNNCNVDHKNTLLIGDSIADLKAA
HHHHHHHHCCCHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCCCCEEEECCCHHHHHHH
INANCHFILVNEPQYQKHMETIINLKPLIVKTIDELETQINHFLY
HCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure 
TKKLIVFDFDGTIMHTHTTMSLSIIGVLEFYNHHIPSLKEMNDLLGNLSMVNIFKKYAK
CCEEEEEECCCEEEEEEEEHHHHHHHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHH
HDLLNIEIEMMISKYYEIYESSLFMIHSYFFDGILDLIKKLKSLNNNVKLAILSNKRSSL
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCCHHHH
LATMVDYYNLRPYFDYIFGAEDVEQMKPDPSGLLKIMNNCNVDHKNTLLIGDSIADLKAA
HHHHHHHHCCCHHHHHHCCCHHHHHCCCCHHHHHHHHHCCCCCCCCEEEECCCHHHHHHH
INANCHFILVNEPQYQKHMETIINLKPLIVKTIDELETQINHFLY
HCCCEEEEEECCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]