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The map label for this gene is kbaY [H]

Identifier: 170683929

GI number: 170683929

Start: 4072681

End: 4073532

Strand: Reverse

Name: kbaY [H]

Synonym: EcSMS35_3994

Alternate gene names: 170683929

Gene position: 4073532-4072681 (Counterclockwise)

Preceding gene: 170683316

Following gene: 170682060

Centisome position: 80.37

GC content: 55.75

Gene sequence:

>852_bases
ATGTTTGCCGATATGAAAAGTATGGTGATGAAAGCCTGGCATGAACATTACGCCTTACTGGCGATCAACTGTATGAATCT
GGAAAGTGCTCACGCAGCTATCCGCGTGGCGGAGAAGAATCGCGCTCCGATCATTCTCAATCTCTATCAGGGGCATCTGG
CGCATTTTCCAGCACCCGTCGCGGCGGCAGTGGTTAAAACGCTCGCGGAATCTGCCTCAGTACCGGTCGCTCTGGCGCTT
GATCATGGCAAAAATCCGGACTGTATTCGTCAGGCGTTTCGTGCTGGTTTCAGCGGATTAATGATTGATGCTTCTGCTTT
TCCCCTGGAGGAAAACGTGCGCCAGACCAGGGCGGTGGTGGAACTCGCCGCCAGCGCGCAGCTCTGCGTGGAAGGCGAAC
TGGGCCATCTGGCAGATGCGCCGCGTTACGACCAGGCCGCCAATGCAGACCTGATGACGCAACCCACTGATGTGGAAACG
TTTATCGCGCAGACAGGCATTGATCTACTGGCCGTCTCGGTAGGCACGGCGCACGGCATGTACGCGCCTGGTGTTGTACC
TGCTATTGATTTTCAGCGTCTGGCGGAGATTTTCCACTGCTCGAGCGTGCCTCTGGCATTACATGGCGGTAGCGGTACGC
CGTTCGATCAGCTCCAGCTCTGTACGACGCTGGGGGTAGCAAAAATCAACGTGGGGGCGGCCATTTTTGAACGGGGGAAA
TCCGCGCTCCTGCATACCCTCTGTCACGATATATCCATTGAACTGGTGGACGCGCTGAAAGCTATGGAACTGGCCTTCGA
AGAAGCGATTACACCGTATTTACAGGCGAGCGGCTCTATCGGCAAAGCCTGA

Upstream 100 bases:

>100_bases
AGAAACCGGTAACGGAACGCGACGAAGAGTTTGACGAACTGAGCGATCAAAAGCTGAAAGATGAAGAGATCACTTTCACC
CTCGAATAACCGGAGGCCCT

Downstream 100 bases:

>100_bases
TTCATTTTCTGTCATGGCCTTTATGCCAGTGCAATAACGCACCGGCAGGGCGGACTACACGCTGAAACTGGAGATTTAAC
ATGTTAGTTTCGATGAAAGA

Product: fructose-bisphosphate aldolase, class II

Products: NA

Alternate protein names: TBPA; TagBP aldolase; D-tagatose-bisphosphate aldolase class II; Ketose 1,6-bisphosphate aldolase class II; Tagatose-bisphosphate aldolase [H]

Number of amino acids: Translated: 283; Mature: 283

Protein sequence:

>283_residues
MFADMKSMVMKAWHEHYALLAINCMNLESAHAAIRVAEKNRAPIILNLYQGHLAHFPAPVAAAVVKTLAESASVPVALAL
DHGKNPDCIRQAFRAGFSGLMIDASAFPLEENVRQTRAVVELAASAQLCVEGELGHLADAPRYDQAANADLMTQPTDVET
FIAQTGIDLLAVSVGTAHGMYAPGVVPAIDFQRLAEIFHCSSVPLALHGGSGTPFDQLQLCTTLGVAKINVGAAIFERGK
SALLHTLCHDISIELVDALKAMELAFEEAITPYLQASGSIGKA

Sequences:

>Translated_283_residues
MFADMKSMVMKAWHEHYALLAINCMNLESAHAAIRVAEKNRAPIILNLYQGHLAHFPAPVAAAVVKTLAESASVPVALAL
DHGKNPDCIRQAFRAGFSGLMIDASAFPLEENVRQTRAVVELAASAQLCVEGELGHLADAPRYDQAANADLMTQPTDVET
FIAQTGIDLLAVSVGTAHGMYAPGVVPAIDFQRLAEIFHCSSVPLALHGGSGTPFDQLQLCTTLGVAKINVGAAIFERGK
SALLHTLCHDISIELVDALKAMELAFEEAITPYLQASGSIGKA
>Mature_283_residues
MFADMKSMVMKAWHEHYALLAINCMNLESAHAAIRVAEKNRAPIILNLYQGHLAHFPAPVAAAVVKTLAESASVPVALAL
DHGKNPDCIRQAFRAGFSGLMIDASAFPLEENVRQTRAVVELAASAQLCVEGELGHLADAPRYDQAANADLMTQPTDVET
FIAQTGIDLLAVSVGTAHGMYAPGVVPAIDFQRLAEIFHCSSVPLALHGGSGTPFDQLQLCTTLGVAKINVGAAIFERGK
SALLHTLCHDISIELVDALKAMELAFEEAITPYLQASGSIGKA

Specific function: Catalytic subunit of the tagatose-1,6-bisphosphate aldolase KbaYZ, which catalyzes the reversible aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to produce tagatose 1,6- bisphosphate (T

COG id: COG0191

COG function: function code G; Fructose/tagatose bisphosphate aldolase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class II fructose-bisphosphate aldolase family. TagBP aldolase KbaY subfamily [H]

Homologues:

Organism=Escherichia coli, GI1789526, Length=232, Percent_Identity=37.5, Blast_Score=149, Evalue=3e-37,
Organism=Escherichia coli, GI87082041, Length=280, Percent_Identity=34.6428571428571, Blast_Score=147, Evalue=1e-36,
Organism=Escherichia coli, GI1788072, Length=231, Percent_Identity=33.7662337662338, Blast_Score=144, Evalue=6e-36,
Organism=Escherichia coli, GI1789293, Length=276, Percent_Identity=29.3478260869565, Blast_Score=77, Evalue=2e-15,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013785
- InterPro:   IPR000771
- InterPro:   IPR011288 [H]

Pfam domain/function: PF01116 F_bP_aldolase [H]

EC number: =4.1.2.40 [H]

Molecular weight: Translated: 30050; Mature: 30050

Theoretical pI: Translated: 5.69; Mature: 5.69

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
5.3 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
5.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFADMKSMVMKAWHEHYALLAINCMNLESAHAAIRVAEKNRAPIILNLYQGHLAHFPAPV
CCCCHHHHHHHHHHHCEEEEEEEECCCHHHHHHEEEECCCCCCEEEEECCCHHHHCCHHH
AAAVVKTLAESASVPVALALDHGKNPDCIRQAFRAGFSGLMIDASAFPLEENVRQTRAVV
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHH
ELAASAQLCVEGELGHLADAPRYDQAANADLMTQPTDVETFIAQTGIDLLAVSVGTAHGM
HHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHEEEECCCCCCC
YAPGVVPAIDFQRLAEIFHCSSVPLALHGGSGTPFDQLQLCTTLGVAKINVGAAIFERGK
CCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHH
SALLHTLCHDISIELVDALKAMELAFEEAITPYLQASGSIGKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure
MFADMKSMVMKAWHEHYALLAINCMNLESAHAAIRVAEKNRAPIILNLYQGHLAHFPAPV
CCCCHHHHHHHHHHHCEEEEEEEECCCHHHHHHEEEECCCCCCEEEEECCCHHHHCCHHH
AAAVVKTLAESASVPVALALDHGKNPDCIRQAFRAGFSGLMIDASAFPLEENVRQTRAVV
HHHHHHHHHHCCCCCEEEEECCCCCHHHHHHHHHCCCCCEEEECCCCCHHHHHHHHHHHH
ELAASAQLCVEGELGHLADAPRYDQAANADLMTQPTDVETFIAQTGIDLLAVSVGTAHGM
HHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHCCHHHEEEECCCCCCC
YAPGVVPAIDFQRLAEIFHCSSVPLALHGGSGTPFDQLQLCTTLGVAKINVGAAIFERGK
CCCCCCCCCCHHHHHHHHHCCCCCEEEECCCCCCHHHHHHHHHHCHHHHHHHHHHHHHHH
SALLHTLCHDISIELVDALKAMELAFEEAITPYLQASGSIGKA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA