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The map label for this gene is abgR [H]

Identifier: 170682963

GI number: 170682963

Start: 1800805

End: 1801713

Strand: Reverse

Name: abgR [H]

Synonym: EcSMS35_1783

Alternate gene names: 170682963

Gene position: 1801713-1800805 (Counterclockwise)

Preceding gene: 170681889

Following gene: 170680790

Centisome position: 35.55

GC content: 49.5

Gene sequence:

>909_bases
ATGGCTTTTCAGGTAAAAATTCATCAAATTCGGGCTTTTGTTGAAGTGGCTCGTCAGGGCAGCATTCGCGGAGCGAGCCG
AATGTTGAATATGTCGCAACCGGCACTGAGTAAATCTATTCAGGAACTGGAAGAAGGGTTGGCGGCACAACTCTTTTTTC
GCCGTAGTAAAGGCGTGACGTTAACTGATGCCGGTGAAAGTTTTTATCAGCACGCCAGTCTTATTCTTGAAGAGCTGCGC
GCAGCGCAAGAGGATATTCGCCAACGACAAGGGCAACTGGCAGGGCAAATTAATATCGGCATGGGGGCCAGTATTTCCCG
CAGTCTGATGCCAGCTGTCATATCTCGTTTTCATCAGCAGCATCCGCAGGTAAAAGTACGCATTATGGAAGGGCAACTGG
TGTCGATGATTAATGAATTGCGCCAGGGAGAACTGGATTTCACCATCAATACCTATTATCAGGGACCCTACGACCACGAA
TTTACTTTTGAGAAATTACTGGAAAAGCAATTCGCGATCTTTTGCCGCCCGGGACATCCCGCCATTGGTGCCCGTTCGAT
CAAACAGTTACTGGACTACAGCTGGACAATGCCGACGCCACACGGCAGCTACTACAAACAGTTGAGTGAATTGCTTGACG
ATCAGGCGCAAACGCCACAGGTCGGCGTAGTCTGCGAGACGTTCTCAGCCTGTATCAGTCTGGTGGCAAAAAGCGATTTT
CTCAGCATACTACCTGAAGAAATGGGCTGCGATCCCTTGCACGGACAGGGGCTGGTGATGTTGCCGGTTAGCGAAATTTT
ACCGAAAGCGACCTATTATTTGATTCAGCGGCGTGATAGTCGCCAGACACCACTGACCGCGTCATTAATCACGCAATTTC
GGCGAGAATGCGGCTATCTGCAAAGTTAA

Upstream 100 bases:

>100_bases
TCACAGTTTTAACCGTTCATAAATTACCCTGACACAATCATCTGCATTAAAGTAGATGCCAGTTTCTTTGGTCTGATAAA
TAACGGTTATCGGTGGCGTC

Downstream 100 bases:

>100_bases
AACTGCATAAAAAAAATAGAGTCTGTCGACATCCGCCAGACTCTACAGTACACACAGCAGTGCATCCGCGTCTTAAATCC
GGCATGGTCTCCTCTGCGCC

Product: putative DNA-binding transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 302; Mature: 301

Protein sequence:

>302_residues
MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELEEGLAAQLFFRRSKGVTLTDAGESFYQHASLILEELR
AAQEDIRQRQGQLAGQINIGMGASISRSLMPAVISRFHQQHPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHE
FTFEKLLEKQFAIFCRPGHPAIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQTPQVGVVCETFSACISLVAKSDF
LSILPEEMGCDPLHGQGLVMLPVSEILPKATYYLIQRRDSRQTPLTASLITQFRRECGYLQS

Sequences:

>Translated_302_residues
MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELEEGLAAQLFFRRSKGVTLTDAGESFYQHASLILEELR
AAQEDIRQRQGQLAGQINIGMGASISRSLMPAVISRFHQQHPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHE
FTFEKLLEKQFAIFCRPGHPAIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQTPQVGVVCETFSACISLVAKSDF
LSILPEEMGCDPLHGQGLVMLPVSEILPKATYYLIQRRDSRQTPLTASLITQFRRECGYLQS
>Mature_301_residues
AFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELEEGLAAQLFFRRSKGVTLTDAGESFYQHASLILEELRA
AQEDIRQRQGQLAGQINIGMGASISRSLMPAVISRFHQQHPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHEF
TFEKLLEKQFAIFCRPGHPAIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQTPQVGVVCETFSACISLVAKSDFL
SILPEEMGCDPLHGQGLVMLPVSEILPKATYYLIQRRDSRQTPLTASLITQFRRECGYLQS

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=302, Percent_Identity=99.3377483443709, Blast_Score=618, Evalue=1e-178,
Organism=Escherichia coli, GI1789506, Length=291, Percent_Identity=27.1477663230241, Blast_Score=137, Evalue=1e-33,
Organism=Escherichia coli, GI87081904, Length=264, Percent_Identity=29.1666666666667, Blast_Score=117, Evalue=1e-27,
Organism=Escherichia coli, GI157672245, Length=294, Percent_Identity=25.1700680272109, Blast_Score=96, Evalue=2e-21,
Organism=Escherichia coli, GI145693105, Length=287, Percent_Identity=25.7839721254355, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788481, Length=198, Percent_Identity=29.2929292929293, Blast_Score=88, Evalue=7e-19,
Organism=Escherichia coli, GI1788297, Length=257, Percent_Identity=26.0700389105058, Blast_Score=79, Evalue=3e-16,
Organism=Escherichia coli, GI1788887, Length=255, Percent_Identity=27.0588235294118, Blast_Score=78, Evalue=8e-16,
Organism=Escherichia coli, GI1788748, Length=169, Percent_Identity=28.9940828402367, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1790208, Length=145, Percent_Identity=28.2758620689655, Blast_Score=76, Evalue=3e-15,
Organism=Escherichia coli, GI1787530, Length=280, Percent_Identity=23.9285714285714, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1790399, Length=145, Percent_Identity=28.9655172413793, Blast_Score=74, Evalue=1e-14,
Organism=Escherichia coli, GI1789440, Length=166, Percent_Identity=28.3132530120482, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI2367136, Length=248, Percent_Identity=27.8225806451613, Blast_Score=70, Evalue=2e-13,
Organism=Escherichia coli, GI87082024, Length=165, Percent_Identity=26.6666666666667, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1789639, Length=126, Percent_Identity=23.8095238095238, Blast_Score=65, Evalue=8e-12,
Organism=Escherichia coli, GI1787806, Length=286, Percent_Identity=21.3286713286713, Blast_Score=64, Evalue=1e-11,
Organism=Escherichia coli, GI1787128, Length=140, Percent_Identity=25.7142857142857, Blast_Score=64, Evalue=2e-11,
Organism=Escherichia coli, GI87081766, Length=245, Percent_Identity=22.8571428571429, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI1787879, Length=292, Percent_Identity=26.027397260274, Blast_Score=63, Evalue=2e-11,
Organism=Escherichia coli, GI48994962, Length=158, Percent_Identity=27.2151898734177, Blast_Score=61, Evalue=9e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 34074; Mature: 33942

Theoretical pI: Translated: 7.57; Mature: 7.57

Prosite motif: PS00041 HTH_ARAC_FAMILY_1 ; PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.7 %Cys     (Translated Protein)
3.3 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
1.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELEEGLAAQLFFRRSKGVT
CCEEHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTDAGESFYQHASLILEELRAAQEDIRQRQGQLAGQINIGMGASISRSLMPAVISRFHQQ
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHH
HPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHEFTFEKLLEKQFAIFCRPGHP
CCCEEEEEECCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHEEEECCCCC
AIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQTPQVGVVCETFSACISLVAKSDF
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LSILPEEMGCDPLHGQGLVMLPVSEILPKATYYLIQRRDSRQTPLTASLITQFRRECGYL
HHHCHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCC
QS
CC
>Mature Secondary Structure 
AFQVKIHQIRAFVEVARQGSIRGASRMLNMSQPALSKSIQELEEGLAAQLFFRRSKGVT
CEEHHHHHHHHHHHHHHCCCCHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCE
LTDAGESFYQHASLILEELRAAQEDIRQRQGQLAGQINIGMGASISRSLMPAVISRFHQQ
EECCHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCHHHHHHHHHHHHHHHHH
HPQVKVRIMEGQLVSMINELRQGELDFTINTYYQGPYDHEFTFEKLLEKQFAIFCRPGHP
CCCEEEEEECCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHHHHHHHEEEECCCCC
AIGARSIKQLLDYSWTMPTPHGSYYKQLSELLDDQAQTPQVGVVCETFSACISLVAKSDF
CCCHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
LSILPEEMGCDPLHGQGLVMLPVSEILPKATYYLIQRRDSRQTPLTASLITQFRRECGYL
HHHCHHHHCCCCCCCCCEEEECHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHCCCC
QS
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]