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The map label for this gene is yidJ [H]

Identifier: 170681583

GI number: 170681583

Start: 4133168

End: 4134661

Strand: Reverse

Name: yidJ [H]

Synonym: EcSMS35_4043

Alternate gene names: 170681583

Gene position: 4134661-4133168 (Counterclockwise)

Preceding gene: 170680795

Following gene: 170680912

Centisome position: 81.58

GC content: 51.94

Gene sequence:

>1494_bases
ATGAAACGCCCCAATTTTCTGTTCATCATGACCGATACCCAGGCCACCAATATGGTCGGTTGCTATAGCGGTAAGCCGCT
GAATACGCAAAATATTGATAGTCTGGCGGCGGAAAGTATTCGCTTTAATTCCGCCTATACCTGTTCACCGGTTTGTACAC
CAGCGCGCGCCGGGCTGTTTACCGGTATCTACGCTAACCAGTCCGGCCCGTGGACCAACAACGTCGCGCCGGGCAAAAAC
ATCTCCACTATGGGACGCTACTTTAAGGATGCGGGCTATCACACCTGTTACATCGGCAAATGGCATCTCGACGGTCATGA
CTATTTCGGCACTGGCGAGTGTCCGCCGGAGTGGGACGCTGATTACTGGTTCGATGGGGCGAACTACCTTAGCGAACTGA
CGGAAAAAGAGATCAGCCTGTGGCGCAATGGCCTAAACAGCGTTGAGGATTTACAGGCGAACCATATCGACGAAACCTTC
ACCTGGGCGCATCGCATCAGCAATCGGGCGGTAGATTTTCTGCAACAGCCCGCGCGCGCCGAGGAACCCTTCCTGATGGT
GGTTTCGTATGATGAGCCGCATCACCCGTTCACCTGTCCGGTGGAGTATTTAGAGAAATACGCTGATTTTTACTACGAAC
TTGGCGAGAAATCACAGGATGACCTGGCGAACAAACCGGAACATCACCGCTTATGGGCGCAGGCGATGCCATCGCCAGTC
GGTGATGACGGGCTTTATCACCATCCGCTCTATTTTGCCTGCAATGACTTTGTTGATGACCAAATCGGACGGGTCATCAA
TGCCTTAACGCCAGAGCAACGTGAAAATACGTGGGTCATTTATACCTCCGATCACGGTGAAATGATGGGCGCACATAAGT
TGATCAGTAAAGGAGCGGCGATGTATGACGACATCACCCGTATTCCGCTGATCATCCGTTCGCCGCAAGGGGAGCGGCGG
CAGGTCGATACGCCAGTCAGTCATATCGATTTACTGCCGACAATGATGGCGCTGGCAGATATTGAAAAACCAGAGATTCT
GCCGGGGGAAAATATCCTTGCCGTGAAAGAGCCACGCGGCGTAATGGTGGAATTTAACCGCTACGAGATTGAGCATGACA
GCTTTGGCGGTTTTATTCCGGTGCGTTGCTGGGTGACGGATGACTTTAAACTGGTACTCAACCTCTTCACCAGTGATGAA
CTTTACGATCGCCGTAATGACCTAAATGAAATGCATAATCTGATCGATGATATCCGTTTTGCCGACGTTCGCCGCAAAAT
GCATGACGCCTTATTGGATTACATGGATAAAATTCGCGATCCGTTCCGCAGTTACCAATGGAGTCTGCGTCCGTGGCGTA
AAGATGCACGACCGCGCTGGATGGGGGCGTTTCGTCCACGCCCACAAGATGGCTATTCGCCAGTGGTACGCGACTATGAC
ACCGGCCTACCGACACAAGGGGTGAAGGTGGAAGAGAAAAAACAGAAGTTCTGA

Upstream 100 bases:

>100_bases
ATTTCATCGCTGCCGTAGTGATTGTCTACCTGATTTTTGACAGCTGGCGGCATCGTCACGACCCAGCCGTAACCTTTACT
CCCGACGCGAAGGATAGCCT

Downstream 100 bases:

>100_bases
TGCATTATTGCTGTTCCTGGCCTACTTTTTCGGCGAGGAACAGTTTACAAGGAGCAACAATGAAAATTTCCCGCCTCGGA
GAAGCGCCCGATTACCGCTT

Product: sulfatase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 497; Mature: 497

Protein sequence:

>497_residues
MKRPNFLFIMTDTQATNMVGCYSGKPLNTQNIDSLAAESIRFNSAYTCSPVCTPARAGLFTGIYANQSGPWTNNVAPGKN
ISTMGRYFKDAGYHTCYIGKWHLDGHDYFGTGECPPEWDADYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETF
TWAHRISNRAVDFLQQPARAEEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKSQDDLANKPEHHRLWAQAMPSPV
GDDGLYHHPLYFACNDFVDDQIGRVINALTPEQRENTWVIYTSDHGEMMGAHKLISKGAAMYDDITRIPLIIRSPQGERR
QVDTPVSHIDLLPTMMALADIEKPEILPGENILAVKEPRGVMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLVLNLFTSDE
LYDRRNDLNEMHNLIDDIRFADVRRKMHDALLDYMDKIRDPFRSYQWSLRPWRKDARPRWMGAFRPRPQDGYSPVVRDYD
TGLPTQGVKVEEKKQKF

Sequences:

>Translated_497_residues
MKRPNFLFIMTDTQATNMVGCYSGKPLNTQNIDSLAAESIRFNSAYTCSPVCTPARAGLFTGIYANQSGPWTNNVAPGKN
ISTMGRYFKDAGYHTCYIGKWHLDGHDYFGTGECPPEWDADYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETF
TWAHRISNRAVDFLQQPARAEEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKSQDDLANKPEHHRLWAQAMPSPV
GDDGLYHHPLYFACNDFVDDQIGRVINALTPEQRENTWVIYTSDHGEMMGAHKLISKGAAMYDDITRIPLIIRSPQGERR
QVDTPVSHIDLLPTMMALADIEKPEILPGENILAVKEPRGVMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLVLNLFTSDE
LYDRRNDLNEMHNLIDDIRFADVRRKMHDALLDYMDKIRDPFRSYQWSLRPWRKDARPRWMGAFRPRPQDGYSPVVRDYD
TGLPTQGVKVEEKKQKF
>Mature_497_residues
MKRPNFLFIMTDTQATNMVGCYSGKPLNTQNIDSLAAESIRFNSAYTCSPVCTPARAGLFTGIYANQSGPWTNNVAPGKN
ISTMGRYFKDAGYHTCYIGKWHLDGHDYFGTGECPPEWDADYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETF
TWAHRISNRAVDFLQQPARAEEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKSQDDLANKPEHHRLWAQAMPSPV
GDDGLYHHPLYFACNDFVDDQIGRVINALTPEQRENTWVIYTSDHGEMMGAHKLISKGAAMYDDITRIPLIIRSPQGERR
QVDTPVSHIDLLPTMMALADIEKPEILPGENILAVKEPRGVMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLVLNLFTSDE
LYDRRNDLNEMHNLIDDIRFADVRRKMHDALLDYMDKIRDPFRSYQWSLRPWRKDARPRWMGAFRPRPQDGYSPVVRDYD
TGLPTQGVKVEEKKQKF

Specific function: Unknown

COG id: COG3119

COG function: function code P; Arylsulfatase A and related enzymes

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the sulfatase family [H]

Homologues:

Organism=Homo sapiens, GI4557659, Length=421, Percent_Identity=26.3657957244656, Blast_Score=109, Evalue=7e-24,
Organism=Homo sapiens, GI189571643, Length=384, Percent_Identity=24.4791666666667, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI189571641, Length=384, Percent_Identity=24.4791666666667, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI189571638, Length=384, Percent_Identity=24.4791666666667, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI189571636, Length=384, Percent_Identity=24.4791666666667, Blast_Score=100, Evalue=3e-21,
Organism=Homo sapiens, GI53831991, Length=410, Percent_Identity=24.6341463414634, Blast_Score=96, Evalue=7e-20,
Organism=Homo sapiens, GI5360208, Length=307, Percent_Identity=28.3387622149837, Blast_Score=95, Evalue=1e-19,
Organism=Homo sapiens, GI240255483, Length=376, Percent_Identity=24.7340425531915, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI29789100, Length=376, Percent_Identity=24.7340425531915, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI240255478, Length=376, Percent_Identity=24.7340425531915, Blast_Score=94, Evalue=2e-19,
Organism=Homo sapiens, GI71852584, Length=437, Percent_Identity=24.9427917620137, Blast_Score=82, Evalue=1e-15,
Organism=Homo sapiens, GI71852586, Length=113, Percent_Identity=38.0530973451327, Blast_Score=77, Evalue=5e-14,
Organism=Homo sapiens, GI157266309, Length=162, Percent_Identity=31.4814814814815, Blast_Score=74, Evalue=2e-13,
Organism=Homo sapiens, GI45430057, Length=395, Percent_Identity=23.7974683544304, Blast_Score=72, Evalue=1e-12,
Organism=Homo sapiens, GI109389362, Length=217, Percent_Identity=27.6497695852535, Blast_Score=71, Evalue=3e-12,
Organism=Homo sapiens, GI59797060, Length=217, Percent_Identity=27.6497695852535, Blast_Score=70, Evalue=7e-12,
Organism=Homo sapiens, GI58743319, Length=113, Percent_Identity=32.7433628318584, Blast_Score=68, Evalue=2e-11,
Organism=Homo sapiens, GI31742482, Length=111, Percent_Identity=32.4324324324324, Blast_Score=67, Evalue=4e-11,
Organism=Homo sapiens, GI4503899, Length=384, Percent_Identity=23.4375, Blast_Score=67, Evalue=5e-11,
Organism=Escherichia coli, GI1790112, Length=497, Percent_Identity=98.7927565392354, Blast_Score=1035, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17568795, Length=371, Percent_Identity=26.6846361185984, Blast_Score=107, Evalue=2e-23,
Organism=Drosophila melanogaster, GI19922168, Length=362, Percent_Identity=27.0718232044199, Blast_Score=118, Evalue=9e-27,
Organism=Drosophila melanogaster, GI24653364, Length=362, Percent_Identity=27.3480662983425, Blast_Score=118, Evalue=1e-26,
Organism=Drosophila melanogaster, GI24647401, Length=395, Percent_Identity=24.3037974683544, Blast_Score=104, Evalue=2e-22,
Organism=Drosophila melanogaster, GI24666109, Length=306, Percent_Identity=23.8562091503268, Blast_Score=81, Evalue=1e-15,
Organism=Drosophila melanogaster, GI281366397, Length=368, Percent_Identity=23.6413043478261, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI281366395, Length=368, Percent_Identity=23.6413043478261, Blast_Score=73, Evalue=5e-13,
Organism=Drosophila melanogaster, GI24666163, Length=368, Percent_Identity=23.6413043478261, Blast_Score=73, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017849
- InterPro:   IPR017850
- InterPro:   IPR000917 [H]

Pfam domain/function: PF00884 Sulfatase [H]

EC number: 3.1.6.- [C]

Molecular weight: Translated: 57455; Mature: 57455

Theoretical pI: Translated: 5.16; Mature: 5.16

Prosite motif: PS00523 SULFATASE_1 ; PS00149 SULFATASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
4.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
3.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKRPNFLFIMTDTQATNMVGCYSGKPLNTQNIDSLAAESIRFNSAYTCSPVCTPARAGLF
CCCCCEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHEECCCCEECCCCCCCHHHHHE
TGIYANQSGPWTNNVAPGKNISTMGRYFKDAGYHTCYIGKWHLDGHDYFGTGECPPEWDA
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCC
DYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETFTWAHRISNRAVDFLQQPARA
CCEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
EEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKSQDDLANKPEHHRLWAQAMPSPV
CCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCCCCC
GDDGLYHHPLYFACNDFVDDQIGRVINALTPEQRENTWVIYTSDHGEMMGAHKLISKGAA
CCCCCEECCHHEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCH
MYDDITRIPLIIRSPQGERRQVDTPVSHIDLLPTMMALADIEKPEILPGENILAVKEPRG
HHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCC
VMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLVLNLFTSDELYDRRNDLNEMHNLIDDIRF
EEEEEEEEEECCCCCCCEEEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ADVRRKMHDALLDYMDKIRDPFRSYQWSLRPWRKDARPRWMGAFRPRPQDGYSPVVRDYD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHCC
TGLPTQGVKVEEKKQKF
CCCCCCCCCCCHHHCCC
>Mature Secondary Structure
MKRPNFLFIMTDTQATNMVGCYSGKPLNTQNIDSLAAESIRFNSAYTCSPVCTPARAGLF
CCCCCEEEEEECCCCCCEEEECCCCCCCCCCHHHHHHHHEECCCCEECCCCCCCHHHHHE
TGIYANQSGPWTNNVAPGKNISTMGRYFKDAGYHTCYIGKWHLDGHDYFGTGECPPEWDA
EEEEECCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEEEEEEECCCCCCCCCCCCCCCCC
DYWFDGANYLSELTEKEISLWRNGLNSVEDLQANHIDETFTWAHRISNRAVDFLQQPARA
CCEECHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHCCCCC
EEPFLMVVSYDEPHHPFTCPVEYLEKYADFYYELGEKSQDDLANKPEHHRLWAQAMPSPV
CCCEEEEEECCCCCCCEECCHHHHHHHHHHHHHHCCCCHHHHCCCCHHHHHHHHHCCCCC
GDDGLYHHPLYFACNDFVDDQIGRVINALTPEQRENTWVIYTSDHGEMMGAHKLISKGAA
CCCCCEECCHHEEHHHHHHHHHHHHHHHCCCCCCCCEEEEEECCCCCHHHHHHHHHCCCH
MYDDITRIPLIIRSPQGERRQVDTPVSHIDLLPTMMALADIEKPEILPGENILAVKEPRG
HHHHHHHCCEEEECCCCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCEEEEECCCC
VMVEFNRYEIEHDSFGGFIPVRCWVTDDFKLVLNLFTSDELYDRRNDLNEMHNLIDDIRF
EEEEEEEEEECCCCCCCEEEEEEEECCCHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHH
ADVRRKMHDALLDYMDKIRDPFRSYQWSLRPWRKDARPRWMGAFRPRPQDGYSPVVRDYD
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCHHCCCCCCCCCCCCCCCCCCCCCHHHHCC
TGLPTQGVKVEEKKQKF
CCCCCCCCCCCHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on ester bonds; Sulfuric ester hydrolases [C]

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7686882; 9278503 [H]