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The map label for this gene is nhoA [H]

Identifier: 170681423

GI number: 170681423

Start: 1719125

End: 1719970

Strand: Reverse

Name: nhoA [H]

Synonym: EcSMS35_1711

Alternate gene names: 170681423

Gene position: 1719970-1719125 (Counterclockwise)

Preceding gene: 170679957

Following gene: 170684244

Centisome position: 33.94

GC content: 51.18

Gene sequence:

>846_bases
ATGACGCCCATTCTGAATCATTATTTTGCCCGTATTAACTGGTCGGGAGCTGCTGCGGCCAATATTGATACGCTGCGTGC
ATTGCACCTGAAACACAATTGCACCATTCCATTTGAAAACCTCGACGTTTTGCTGCCAAGGGAAATACAGCTTGATGATC
AATCGCTGGAAGAGAAACTGGTGACAGCCCGTCGTGGCGGTTACTGTTTTGAGCAGAATGGCGTGTTTGAGCGTGTGTTA
CGCGAGCTGGGGTTTAACGTTCGCAGCTTGTTAGGGCGCGTAGTGTTATCAAATCCGCCAGCATTACCGCCGCGCACCCA
TCGTTTGTTGTTGGTGGAACTGGAAGGGGAAAAATGGATTGCTGATGTCGGTTTCGGTGGACAGACGCTAACCGCGCCGA
TTCGGTTAGTTCCCGAGCTCGTGCAGACCACGCCACACGGAGAGTATCGGTTGTTGCAGGAGGGTGATGATTGGGTGTTG
CAGTTTAATCATCATCAGCACTGGCAGTCGATGTACCGTTTTGATCTCTGCGAGCAGCAACAAAGCGATTATGTGATGGG
CAATTTCTGGTCGGCGCATTGGCCGCAGTCGCATTTTCGCCATCATTTGCTGATGTGCCGCCATTTACCGGACGGCGGCA
AGCTGACACTGACCAATTTTCATTTTACCCATTATGAAAATGGGCACGCAGTTGAGCAGCGAAATCTACCAGATGTGGCG
TCGTTATATGCCGTGATGCAGGAACAGTTTGGTCTGGGCGTAGATGATGCGAAACATGGCTTTACTGTGGATGAGTTAGC
GCTGGTGATGGCGGCGTTTGATACGCACCCGGAGGCGGGAAAATAA

Upstream 100 bases:

>100_bases
GCGATTTGCGAACGTGATGCATGTCCGCGATCGCACAAAATAGCCGGTGCAGCGTCTATTCCAGGTTATAAGTTGAGAAA
ACCACTAAGGGAAACGCCTG

Downstream 100 bases:

>100_bases
TTTATGTCAGGTTGCCGGATGTGGCGTAAATGCCTAATCCGGCATACATTAGTCCGGTTGTAGGCCTGATAAGCGAAGCG
CATCAGGCAACGGTTTCAGA

Product: N-hydroxyarylamine O-acetyltransferase

Products: NA

Alternate protein names: Arylamine N-acetyltransferase; Arylhydroxamate N,O-acetyltransferase; NAT102 [H]

Number of amino acids: Translated: 281; Mature: 280

Protein sequence:

>281_residues
MTPILNHYFARINWSGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEEKLVTARRGGYCFEQNGVFERVL
RELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLVPELVQTTPHGEYRLLQEGDDWVL
QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK

Sequences:

>Translated_281_residues
MTPILNHYFARINWSGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEEKLVTARRGGYCFEQNGVFERVL
RELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLVPELVQTTPHGEYRLLQEGDDWVL
QFNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
>Mature_280_residues
TPILNHYFARINWSGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEEKLVTARRGGYCFEQNGVFERVLR
ELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWIADVGFGGQTLTAPIRLVPELVQTTPHGEYRLLQEGDDWVLQ
FNHHQHWQSMYRFDLCEQQQSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVAS
LYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK

Specific function: Unknown

COG id: COG2162

COG function: function code Q; Arylamine N-acetyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the arylamine N-acetyltransferase family [H]

Homologues:

Organism=Homo sapiens, GI237649128, Length=285, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649126, Length=285, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649124, Length=285, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649122, Length=285, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649119, Length=285, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI42741671, Length=285, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649009, Length=285, Percent_Identity=24.5614035087719, Blast_Score=69, Evalue=4e-12,
Organism=Homo sapiens, GI237649132, Length=290, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=5e-12,
Organism=Homo sapiens, GI237649130, Length=290, Percent_Identity=24.1379310344828, Blast_Score=69, Evalue=5e-12,
Organism=Escherichia coli, GI1787736, Length=281, Percent_Identity=97.508896797153, Blast_Score=553, Evalue=1e-159,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001447 [H]

Pfam domain/function: PF00797 Acetyltransf_2 [H]

EC number: =2.3.1.118 [H]

Molecular weight: Translated: 32204; Mature: 32073

Theoretical pI: Translated: 6.32; Mature: 6.32

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPILNHYFARINWSGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEEKL
CCCHHCCCEEEEECCCCCCCCHHHHHEEEECCCCCCCCCCCCEECCCEECCCHHHHHHHH
VTARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWI
HHHHCCCEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEE
ADVGFGGQTLTAPIRLVPELVQTTPHGEYRLLQEGDDWVLQFNHHQHWQSMYRFDLCEQQ
EECCCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
QSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
CCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHH
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC
>Mature Secondary Structure 
TPILNHYFARINWSGAAAANIDTLRALHLKHNCTIPFENLDVLLPREIQLDDQSLEEKL
CCHHCCCEEEEECCCCCCCCHHHHHEEEECCCCCCCCCCCCEECCCEECCCHHHHHHHH
VTARRGGYCFEQNGVFERVLRELGFNVRSLLGRVVLSNPPALPPRTHRLLLVELEGEKWI
HHHHCCCEEECCCCHHHHHHHHHCCCHHHHHHHHHHCCCCCCCCCCCEEEEEEECCCEEE
ADVGFGGQTLTAPIRLVPELVQTTPHGEYRLLQEGDDWVLQFNHHQHWQSMYRFDLCEQQ
EECCCCCCEEHHHHHHHHHHHHCCCCCCEEEEECCCCEEEEECCHHHHHHHHHHHHHHHH
QSDYVMGNFWSAHWPQSHFRHHLLMCRHLPDGGKLTLTNFHFTHYENGHAVEQRNLPDVA
CCCEEEECCCCCCCCHHHHHHHHHHHHCCCCCCEEEEEEEEEEEECCCCCCCCCCCCHHH
SLYAVMQEQFGLGVDDAKHGFTVDELALVMAAFDTHPEAGK
HHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503 [H]